Skip to main content

Induced pluripotent stem cell-based therapy for spinal regeneration

Project description

Novel treatment for intervertebral disc degeneration

The EU-funded iPSpine project is leading the research efforts to develop an advanced therapy medicinal product (ATMP), based on a radically new strategy that employs induced pluripotent stem cells and smart biomaterials. iPSpine aims to improve outcome and quality of life for millions of patients with disc-related lower back pain, through effective regeneration of the diseased disc with restored biomechanical function, and long-lasting reduction of pain. The outcomes of the iPSpine project include platforms of knowledge, testing, and exploitation with broad applicability. iPSpine will make a significant contribution to the field, reducing translational bottlenecks through open innovation and cementing European leadership in the development of ATMPs for treatment of large patient groups.

Call for proposal

H2020-SC1-BHC-2018-2020

See other projects for this call

Sub call

H2020-SC1-2018-Single-Stage-RTD

Coordinator

UNIVERSITEIT UTRECHT
Net EU contribution
€ 3 303 164,75
Address
Heidelberglaan 8
3584 CS Utrecht
Netherlands

See on map

Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (23)

TECHNISCHE UNIVERSITEIT EINDHOVEN
Netherlands
Net EU contribution
€ 1 306 771,25
Address
Groene Loper 3
5612 AE Eindhoven

See on map

Region
Noord-Brabant Zuidoost-Noord-Brabant
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
NANTES UNIVERSITE
France
Net EU contribution
€ 1 093 856,25
Address
1 Quai De Tourville
44000 Nantes

See on map

Region
Pays de la Loire Pays de la Loire Loire-Atlantique
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

CAPACITES
France
Net EU contribution
€ 77 081,25
Address
1 Quai De Tourville
44000 Nantes

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Pays de la Loire Pays de la Loire Loire-Atlantique
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

ECOLE NATIONALE VETERINAIRE, AGROALIMENTAIRE ET DE L'ALIMENTATION NANTES ATLANTIQUE
France
Net EU contribution
€ 79 375,00
Address
Site De La Chantrerie, Route De Gachet
44307 Nantes

See on map

Region
Pays de la Loire Pays de la Loire Loire-Atlantique
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 708 710,00
Address
Heidelberglaan 100
3584 CX Utrecht

See on map

Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
NATIONAL UNIVERSITY OF IRELAND GALWAY
Ireland
Net EU contribution
€ 671 935,00
Address
University Road
H91 Galway

See on map

Region
Ireland Eastern and Midland Dublin
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAET ULM
Germany
Net EU contribution
€ 501 583,75
Address
Helmholtzstrasse 16
89081 Ulm

See on map

Region
Baden-Württemberg Tübingen Ulm, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAET BERN
Switzerland
Net EU contribution
€ 419 000,00
Address
Hochschulstrasse 6
3012 Bern

See on map

Region
Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 826 617,50
Address
Rue De Tolbiac 101
75654 Paris

See on map

Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN
Germany
Net EU contribution
€ 667 156,25
Address
Markwiesenstrasse 55
72770 Reutlingen

See on map

Region
Baden-Württemberg Tübingen Reutlingen
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

EBERHARD KARLS UNIVERSITAET TUEBINGEN
Germany
Net EU contribution
€ 200 000,00
Address
Geschwister-scholl-platz
72074 Tuebingen

See on map

Region
Baden-Württemberg Tübingen Tübingen, Landkreis
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
AO-FORSCHUNGSINSTITUT DAVOS
Switzerland
Net EU contribution
€ 491 250,00
Address
Clavadelerstrasse 8
7270 Davos Platz

See on map

Region
Schweiz/Suisse/Svizzera Ostschweiz Graubünden / Grigioni / Grischun
Activity type
Research Organisations
Non-EU contribution
€ 0,00
SHEFFIELD HALLAM UNIVERSITY
United Kingdom
Net EU contribution
€ 1 126 572,50
Address
Howard Street City Campus
S1 1WB Sheffield

See on map

Region
Yorkshire and the Humber South Yorkshire Sheffield
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITA CAMPUS BIO MEDICO DI ROMA
Italy
Net EU contribution
€ 557 975,00
Address
Via Alvaro Del Portillo 21
00128 Roma

See on map

Region
Centro (IT) Lazio Roma
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
NTRANS TECHNOLOGIES BV
Netherlands
Net EU contribution
€ 770 625,00
Address
J.h. Oortweg 19
2333 CH Leiden

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITE DE MONTPELLIER
France
Net EU contribution
€ 364 903,75
Address
163 Rue Auguste Broussonnet
34090 Montpellier

See on map

Region
Occitanie Languedoc-Roussillon Hérault
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITY OF MIAMI
United States
Net EU contribution
€ 250 175,00
Address
1320 South Dixie Highway, Suite 1200
33146 Coral Gables Miami

See on map

Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
SPINESERV GMBH & CO.KG
Germany
Net EU contribution
€ 321 250,00
Address
Soeflinger Strasse 100
89077 Ulm

See on map

Region
Baden-Württemberg Tübingen Ulm, Stadtkreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
THE UNIVERSITY OF HONG KONG
Hong Kong
Net EU contribution
€ 0,00
Non-EU contribution
€ 436 250,00
PHARMALEX GMBH
Germany
Net EU contribution
€ 676 381,25
Address
Bahnstrasse 42-46
61381 Friedrichsdorf

See on map

Region
Darmstadt Hochtaunuskreis
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Catalyze B.V.
Netherlands
Net EU contribution
€ 274 036,54
Address
Joop-geesinkweg 167
1114 AB Amsterdam-duivendrecht

See on map

SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Stichting ReumaNederland
Netherlands
Net EU contribution
€ 52 213,46
Address
Dr J Van Breemenstraat 4
1056 AB Amsterdam

See on map

Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Other
Non-EU contribution
€ 0,00
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
Net EU contribution
€ 219 147,75
Address
Albinusdreef 2
2333 ZA Leiden

See on map

Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00