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CORDIS

BIOPRINTING BY LIGHT-SHEET LITHOGRAPHY: ENGINEERING COMPLEX TISSUES WITH HIGH RESOLUTION AT HIGH SPEED

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

BRIGHTER web site and logo (opens in new window)

It will include basic project information, logo, news and events, downloadable e-newsletters, and links to social media accounts (tweeter, Facebook and LinkedIn). It is a living document.

Characterization of first batch of hydrogels (opens in new window)

Calibration of the crosslinking density and stiffness of hydrogels formed by light-sheet illumination as a function of the exposure dose.

Initial specifications of the pattern generator (opens in new window)

Description of the requirements and technical specifications of the pattern generator to be applied to the light-sheet bioprinting system

Photopolymerizable polymers biocompatibility (opens in new window)

Experimental procedure and characterization of the functionalization of the photopolymerizable polymers to promote cell adhesion. Evaluation of biocompatibility.

Reconstitution of epidermis and dermis (opens in new window)

Development and characterization of a skin samples composed of dermis and epidermis layers including the rete ridge 3D structures

Characterization of reversible crosslinked IPNs hydrogels (opens in new window)

Calibration of the crosslinking density and stiffness of reversible crosslinkable and IPNs hydrogels formed by lightsheet illumination as a function of the exposure dose

Report on the light-sheet bioprinter process characteristics (opens in new window)

Description of the technical parameters to produce crosslinked hydrogels with the lightsheet illumination set up

Report on networking activities (opens in new window)

Framework document for project networking activities. It will outline the connections and initiatives where the project partners are involved to maximize the project results.

Cell viability on IPNs cell-laden hydrogels (opens in new window)

Cell viability on cellladen IPNs hydrogels polymerized under lightsheet illumination within the dedicated bioprinting chambers

Cell viability on cell-laden hydrogels (opens in new window)

Cell viability on cellladen hydrogels polymerized under lightsheet illumination within the dedicated bioprinting chambers

Report of kick-off meeting (opens in new window)

Minutes of the kick-off meeting including the agenda, list of participants with their affiliations and roles, and presentations of participants

Protocols to isolate, culture and characterize relevant skin cells (opens in new window)

Protocols describing specific cell preparation to be used in combination with BRIGHTER polymers and device

Project Workshop (opens in new window)

Organization of a project workshop, to promote the exchange of PhD students among the consortium members

Publications

A dynamic acousto-optic lithographic patterning technique for bioprinting

Author(s): Rosemarie Ohanyan
Published in: 2022
Publisher: KTH Royal Institute of Technology

Evaluation of optical methods for 3D-printing of tissue

Author(s): Jim Larsson
Published in: 2020
Publisher: KTH Royal Institute of Technology

Ephrin Micropatterns Exogenously Modulate Cell Organization in Organoid-Derived Intestinal Epithelial Monolayers (opens in new window)

Author(s): Enara Larrañaga, Vanesa Fernández-Majada, Samuel Ojosnegros, Jordi Comelles,* and Elena Martinez
Published in: Adv. Mater. Interfaces, 2022, ISSN 2196-7350
Publisher: Weinheim, Germany : Wiley-VCH, 2014-
DOI: 10.1002/admi.202201301

Stem cell responses to stretch and strain (opens in new window)

Author(s): Swarnabh Bhattacharya , Haguy Wolfenson , Ramesh Shivdasani , Ruby Shalom-Feuerstein 
Published in: Trends in Cell Biology, 2022, ISSN 1879-3088
Publisher: Cambridge, UK : Elsevier Science Publishers, c1991-
DOI: 10.1016/j.tcb.2021.10.007

Multi-Modal and Molecular Imaging of Cellular Microenvironment and Tissue Development (opens in new window)

Author(s): Francesco Pampaloni
Published in: International Journal of Molecular Sciences, 2022, ISSN 2572-1100
Publisher: Juniper Publishers
DOI: 10.3390/ijms23137113

Upgrading a Consumer Stereolithographic 3D Printer to Produce a Physiologically Relevant Model with Human Liver Cancer Organoids (opens in new window)

Author(s): Louise Breideband, Kaja N Wächtershäuser, Levin Hafa, Konstantin Wieland, Achilleas S Frangakis, Ernst HK Stelzer, Francesco Pampaloni
Published in: Advanced Materials Technologies, 2022, ISSN 2365-709X
Publisher: Wiley Blackwell
DOI: 10.1002/admt.202200029

Spotlighting adult stem cells: advances, pitfalls, and challenges (opens in new window)

Author(s): Anna Altshuler, Sara A Wickström, Ruby Shalom-Feuerstein 
Published in: Trends in Cell Biology, 2022, ISSN 1879-3088
Publisher: Cambridge, UK : Elsevier Science Publishers
DOI: 10.1016/j.tcb.2022.09.007

MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity (opens in new window)

Author(s): Arne Peirsman, Eva Blondeel, Tasdiq Ahmed, Jasper Anckaert, Dominique Audenaert, Tom Boterberg, Krisztina Buzas, Neil Carragher, Gastone Castellani, Flávia Castro, Virginie Dangles-Marie, John Dawson, Pascal De Tullio, Elly De Vlieghere, Sándor Dedeyne, Herman Depypere, Akos Diosdi, Ruslan I. Dmitriev, Helmut Dolznig, Suzanne Fischer, Christian Gespach, Vera Goossens, Jyrki Heino, An Hendrix, Pe
Published in: Nature Methods, 2021, ISSN 1548-7105
Publisher: New York, NY : Nature Pub. Group, c2004-
DOI: 10.1038/s41592-021-01291-4

Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis (opens in new window)

Author(s): Lotta Hof, Till Moreth, Michael Koch, Tim Liebisch, Marina Kurtz, Julia Tarnick, Susanna M. Lissek, Monique M. A. Verstegen, Luc J. W. van der Laan, Meritxell Huch, Franziska Matthäus, Ernst H. K. Stelzer & Francesco Pampaloni
Published in: BMC Biology, 2021, ISSN 1741-7007
Publisher: BioMed Central
DOI: 10.1186/s12915-021-00958-w

Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing (opens in new window)

Author(s): Anna Altshuler, Aya Amitai-Lange, Noam Tarazi, Sunanda Dey, Lior Strinkovsky, Shira Hadad-Porat, Swarnabh Bhattacharya, Waseem Nasser, Jusuf Imeri, Gil Ben-David, Ghada Abboud-Jarrous, Beatrice Tiosano, Eran Berkowitz, Nathan Karin, Yonatan Savir, Ruby Shalom-Feuerstein
Published in: Cell Stem Cell, 2022, ISSN 1875-9777
Publisher: Elsevier
DOI: 10.1016/j.stem.2021.04.003

Capturing limbal epithelial stem cell population dynamics, signature, and their niche (opens in new window)

Author(s): Anna Altshuler , Aya Amitai-Lange , Noam Tarazi, Sunanda Dey, Lior Strinkovsky, Swarnabh Bhattacharya, Shira Hadad-Porat, Waseem Nasser, Jusuf Imeri, Gil Ben-David, Beatrice Tiosano, Eran Berkowitz, Nathan Karin, Yonatan Savir, Ruby Shalom-Feuerstein
Published in: bioRxiv, 2020, ISSN 2692-8205
Publisher: COLD SPRING HARBOR LABORATORY
DOI: 10.1101/2020.06.30.179754

Intellectual Property Rights

DEVICE AND METHOD FOR STEREOLITHOGRAPHIC THREE DIMENSIONAL PRINTING

Application/Publication number: PCT EP2021/072200
Date: 2021-08-09
Applicant(s): JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN

DEVICE AND METHOD FOR STEREOLITHOGRAPHIC THREE DIMENSIONAL PRINTING

Application/Publication number: PCT EP2021/072200
Date: 2021-08-09
Applicant(s): UNIVERSITAT DE BARCELONA

DEVICE AND METHOD FOR STEREOLITHOGRAPHIC THREE DIMENSIONAL PRINTING

Application/Publication number: PCT EP2021/072200
Date: 2021-08-09
Applicant(s): MYCRONIC AB

DEVICE AND METHOD FOR STEREOLITHOGRAPHIC THREE DIMENSIONAL PRINTING

Application/Publication number: PCT EP2021/072200
Date: 2021-08-09
Applicant(s): FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA

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