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Exploiting the Tumor Proteome Activity Status for Future Cancer Therapies

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Publications

Proteome activity landscapes of tumor cell lines determine drug responses

Author(s): Martin Frejno, Chen Meng, Benjamin Ruprecht, Thomas Oellerich, Sebastian Scheich, Karin Kleigrewe, Enken Drecoll, Patroklos Samaras, Alexander Hogrebe, Dominic Helm, Julia Mergner, Jana Zecha, Stephanie Heinzlmeir, Mathias Wilhelm, Julia Dorn, Hans-Michael Kvasnicka, Hubert Serve, Wilko Weichert, Bernhard Kuster
Published in: Nature Communications, 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-17336-9

Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing

Author(s): Jana Zecha, Chien-Yun Lee, Florian P. Bayer, Chen Meng, Vincent Grass, Johannes Zerweck, Karsten Schnatbaum, Thomas Michler, Andreas Pichlmair, Christina Ludwig, Bernhard Kuster
Published in: Molecular & Cellular Proteomics, 19/9, 2020, Page(s) 1503-1522, ISSN 1535-9476
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.ra120.002164

Evaluation of Disposable Trap Column nanoLC-FAIMS-MS/MS for the Proteomic Analysis of FFPE Tissue

Author(s): Stephan Eckert, Yun-Chien Chang, Florian P Bayer, Matthew The, Peer-Hendrik Kuhn, Wilko Weichert, Bernhard Kuster
Published in: Journal of Proteome Research, 20(12), 2021, Page(s) 5402-5411, ISSN 1535-3893
Publisher: American Chemical Society
DOI: 10.1021/acs.jproteome.1c00695

Identification of 7 000-9 000 Proteins from Cell Lines and Tissues by Single-Shot Microflow LC-MS/MS.

Author(s): Yangyang Bian; Yangyang Bian; Piero Giansanti; Julia Mergner; Runsheng Zheng; Mathias Wilhelm; Alexander Boychenko; Bernhard Kuster
Published in: Analytical Chemistry, 93(25), 2021, Page(s) 8687-8692, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.1c00738

Defining the carrier proteome limit for single-cell proteomics

Author(s): Tommy K Cheung, Chien-Yun Lee, Florian P Bayer, Atticus McCoy, Bernhard Kuster, Christopher M Rose
Published in: Nature Methods, 18(1), 2021, Page(s) 76-83, ISSN 1548-7091
Publisher: Nature Publishing Group
DOI: 10.1038/s41592-020-01002-5

Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling

Author(s): Jana Zecha, Wassim Gabriel, Ria Spalek, Yun-Chien Chang, Julia Mergner, Mathias Wilhelm, Florian Bassermann, Bernhard Kuster
Published in: Nature communications, 13(1), 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27639-0

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS

Author(s): Yangyang Bian, Runsheng Zheng, Florian P. Bayer, Cassandra Wong, Yun-Chien Chang, Chen Meng, Daniel P. Zolg, Maria Reinecke,Jana Zecha, Svenja Wiechmann, Stephanie Heinzlmeir, Johannes Scherr, Bernhard Hemmer,Mike Baynham, Anne-Claude Gingras, Oleksandr Boychenko, and Bernhard Kuster
Published in: Nature communications, 11(1), 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-019-13973-x