Exploiting the Tumor Proteome Activity Status for Future Cancer Therapies

Publikacje

Proteome activity landscapes of tumor cell lines determine drug responses

Autorzy: Martin Frejno, Chen Meng, Benjamin Ruprecht, Thomas Oellerich, Sebastian Scheich, Karin Kleigrewe, Enken Drecoll, Patroklos Samaras, Alexander Hogrebe, Dominic Helm, Julia Mergner, Jana Zecha, Stephanie Heinzlmeir, Mathias Wilhelm, Julia Dorn, Hans-Michael Kvasnicka, Hubert Serve, Wilko Weichert, Bernhard Kuster
Opublikowane w: Nature Communications, Numer 11/1, 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-020-17336-9

Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing

Autorzy: Jana Zecha, Chien-Yun Lee, Florian P. Bayer, Chen Meng, Vincent Grass, Johannes Zerweck, Karsten Schnatbaum, Thomas Michler, Andreas Pichlmair, Christina Ludwig, Bernhard Kuster
Opublikowane w: Molecular & Cellular Proteomics, Numer 19/9, 2020, Strona(/y) 1503-1522, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/mcp.ra120.002164

CurveCurator: a recalibrated F-statistic to assess, classify, and explore significance of dose-response curves

Autorzy: Bayer FP, Gander M, Kuster B, The M
Opublikowane w: Nature Communications, Numer 14(1), 2023, Strona(/y) 7902, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-023-43696-z

Evaluation of Disposable Trap Column nanoLC-FAIMS-MS/MS for the Proteomic Analysis of FFPE Tissue

Autorzy: Stephan Eckert, Yun-Chien Chang, Florian P Bayer, Matthew The, Peer-Hendrik Kuhn, Wilko Weichert, Bernhard Kuster
Opublikowane w: Journal of Proteome Research, Numer 20(12), 2021, Strona(/y) 5402-5411, ISSN 1535-3893
Wydawca: American Chemical Society
DOI: 10.1021/acs.jproteome.1c00695

Identification of 7 000-9 000 Proteins from Cell Lines and Tissues by Single-Shot Microflow LC-MS/MS.

Autorzy: Yangyang Bian; Yangyang Bian; Piero Giansanti; Julia Mergner; Runsheng Zheng; Mathias Wilhelm; Alexander Boychenko; Bernhard Kuster
Opublikowane w: Analytical Chemistry, Numer 93(25), 2021, Strona(/y) 8687-8692, ISSN 0003-2700
Wydawca: American Chemical Society
DOI: 10.1021/acs.analchem.1c00738

Defining the carrier proteome limit for single-cell proteomics

Autorzy: Tommy K Cheung, Chien-Yun Lee, Florian P Bayer, Atticus McCoy, Bernhard Kuster, Christopher M Rose
Opublikowane w: Nature Methods, Numer 18(1), 2021, Strona(/y) 76-83, ISSN 1548-7091
Wydawca: Nature Publishing Group
DOI: 10.1038/s41592-020-01002-5

SIMSI-Transfer: Software-Assisted Reduction of Missing Values in Phosphoproteomic and Proteomic Isobaric Labeling Data Using Tandem Mass Spectrum Clustering

Autorzy: Firas Hamood, Florian P Bayer, Mathias Wilhelm, Bernhard Kuster, Matthew The
Opublikowane w: Molecular & Cellular Proteomics, Numer 21(8), 2022, Strona(/y) 100238, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100238

Decrypting drug actions and protein modifications by dose- and time-resolved proteomics

Autorzy: Zecha J, Bayer FP, Wiechmann S, Woortman J, Berner N, Müller J, Schneider A, Kramer K, Abril-Gil M, Hopf T, Reichart L, Chen L, Hansen FM, Lechner S, Samaras P, Eckert S, Lautenbacher L, Reinecke M, Hamood F, Prokofeva P, Vornholz L, Falcomatà C, Dorsch M, Schröder A, Venhuizen A, Wilhelm S, Médard G, Stoehr G, Ruland J, Grüner BM, Saur D, Buchner M, Ruprecht B, Hahne H, The M, Wilhelm M, Kus
Opublikowane w: Science, Numer 380(6640), 2023, Strona(/y) 93–101, ISSN 0036-8075
Wydawca: American Association for the Advancement of Science
DOI: 10.1126/science.ade3925

Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics

Autorzy: Lee CY, The M, Meng C, Bayer FP, Putzker K, Müller J, Streubel J, Woortman J, Sakhteman A, Resch M, Schneider A, Wilhelm S, Kuster B
Opublikowane w: Molecular Systems Biology, Numer 20(1), 2023, Strona(/y) 28-55, ISSN 1744-4292
Wydawca: Nature Publishing Group
DOI: 10.1038/s44320-023-00004-7

Reanalysis of ProteomicsDB Using an Accurate, Sensitive, and Scalable False Discovery Rate Estimation Approach for Protein Groups

Autorzy: Matthew The, Patroklos Samaras, Bernhard Kuster, Mathias Wilhelm
Opublikowane w: Molecular & Cellular Proteomics, Numer 21(12), 2022, Strona(/y) 100437, ISSN 1535-9476
Wydawca: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.mcpro.2022.100437

Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling

Autorzy: Jana Zecha, Wassim Gabriel, Ria Spalek, Yun-Chien Chang, Julia Mergner, Mathias Wilhelm, Florian Bassermann, Bernhard Kuster
Opublikowane w: Nature communications, Numer 13(1), 2022, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-021-27639-0

Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC-MS/MS

Autorzy: Yangyang Bian, Runsheng Zheng, Florian P. Bayer, Cassandra Wong, Yun-Chien Chang, Chen Meng, Daniel P. Zolg, Maria Reinecke,Jana Zecha, Svenja Wiechmann, Stephanie Heinzlmeir, Johannes Scherr, Bernhard Hemmer,Mike Baynham, Anne-Claude Gingras, Oleksandr Boychenko, and Bernhard Kuster
Opublikowane w: Nature communications, Numer 11(1), 2020, ISSN 2041-1723
Wydawca: Nature Publishing Group
DOI: 10.1038/s41467-019-13973-x

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