Predicting Routes Of Tumour Evolution driven by Unstable genomes and Selection

Pubblicazioni

Induction of APOBEC3 Exacerbates DNA Replication Stress and Chromosomal Instability in Early Breast and Lung Cancer Evolution

Autori: Subramanian Venkatesan, Mihaela Angelova, Clare Puttick, Haoran Zhai, Deborah R. Caswell, Wei-Ting Lu, Michelle Dietzen, Panagiotis Galanos, Konstantinos Evangelou, Roberto Bellelli, Emilia L. Lim, Thomas B.K. Watkins, Andrew Rowan, Vitor H. Teixeira, Yue Zhao, Haiquan Chen, Bryan Ngo, Lykourgos-Panagiotis Zalmas, Maise Al Bakir, Sebastijan Hobor, Eva Grönroos, Adam Pennycuick, Ersilia Nigro, Bri
Pubblicato in: Cancer Discovery, 2020, ISSN 2159-8274
Editore: American Association for Cancer Research Inc.
DOI: 10.1158/2159-8290.cd-20-0725

Pervasive chromosomal instability and karyotype order in tumour evolution

Autori: Thomas B. K. Watkins, Emilia L. Lim, Marina Petkovic, Sergi Elizalde, Nicolai J. Birkbak, Gareth A. Wilson, David A. Moore, Eva Grönroos, Andrew Rowan, Sally M. Dewhurst, Jonas Demeulemeester, Stefan C. Dentro, Stuart Horswell, Lewis Au, Kerstin Haase, Mickael Escudero, Rachel Rosenthal, Maise Al Bakir, Hang Xu, Kevin Litchfield, Wei Ting Lu, Thanos P. Mourikis, Michelle Dietzen, Lavinia Spain, G
Pubblicato in: Nature, 2020, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-020-2698-6

Capturing cancer evolution using genetically engineered mouse models (GEMMs)

Autori: William Hill, Deborah R.Caswell, Charles Swanton
Pubblicato in: Trends in Cell Biology, 2021, ISSN 0962-8924
Editore: Elsevier BV
DOI: 10.1016/j.tcb.2021.07.003

Impact of risk factors on early cancer evolution

Autori: Clare E. Weeden, William Hill, Emilia L. Lim, Eva Grönroos, Charles Swanton
Pubblicato in: Cell, 2023, ISSN 0092-8674
Editore: Cell Press
DOI: 10.1016/j.cell.2023.03.013

Lung adenocarcinoma promotion by air pollutants

Autori: William Hill, Emilia L Lim, Clare E Weeden, Claudia Lee, Marcellus Augustine, Kezhong Chen, Feng-Che Kuan, Fabio Marongiu, Edward J Evans Jr, David A Moore, Felipe S Rodrigues, Oriol Pich, Bjorn Bakker, Hongui Cha, Renelle Myers, Febe van Maldegem, Jesse Boumelha, Selvaraju Veeriah, Andrew Rowan, Cristina Naceur-Lombardelli, Takahiro Karasaki, Monica Sivakumar, Swapnanil De, Deborah R Caswell, Ai
Pubblicato in: Nature, 2023, ISSN 0028-0836
Editore: Nature Publishing Group
DOI: 10.1038/s41586-023-05874-3

A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer

Autori: Hongchen Cai; Su Kit Chew; Chuan Li; Min K. Tsai; Laura Andrejka; Christopher W. Murray; Nicholas W. Hughes; Emily G. Shuldiner; Emily L. Ashkin; Rui Tang; King L. Hung; Leo C Chen; Shi Ya C. Lee; Maryam Yousefi; Wen-Yang Lin; Christian A. Kunder; Le Cong; Christopher D. McFarland; Dmitri A. Petrov; Charles Swanton; Monte M. Winslow
Pubblicato in: Cancer Discovery, vol 11, iss 7, Numero 1, 2021, Pagina/e 1754–1773, ISSN 2159-8290
Editore: AACR
DOI: 10.1158/2159-8290.cd-20-1325

ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis

Autori: Marc Hennequart; Steven E. Pilley; Christiaan F. Labuschagne; Jack Coomes; Loic Mervant; Paul C. Driscoll; Nathalie M. Legrave; Younghwan Lee; Peter Kreuzaler; Benedict Macintyre; Yulia Panina; Julianna Blagih; David Stevenson; Douglas Strathdee; Deborah Schneider-Luftman; Eva Grönroos; Eric C. Cheung; Mariia Yuneva; Charles Swanton; Karen H. Vousden
Pubblicato in: Crossref, Numero 3, 2023, Pagina/e 1-18, ISSN 2211-1247
Editore: Cell Press
DOI: 10.1016/j.celrep.2023.112562

Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

Autori: Robert E. Hynds, Kristopher K. Frese, David R. Pearce, Eva Grönroos, Caroline Dive, Charles Swanton
Pubblicato in: Open Biology, 2021, ISSN 2046-2441
Editore: Royal Society Publishing
DOI: 10.1098/rsob.200247

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