Periodic Reporting for period 1 - INCYPRO (A Technology for the Generation of Stable Enzymes)
Reporting period: 2019-02-01 to 2020-07-31
The general awareness towards a sustainable life style is growing in society. This translates into a growing market for services and products that involve environment-friendly chemistry and material loops. Biotechnology will be one the key drivers when aiming for a circular economy, as it facilitates green chemistry and efficient recycling processes. A central component of most biotechnological processes are biocatalytic proteins (so-called enzymes). However, enzymes are intrinsically vulnerable to unnatural microenvironments hampering their wide-spread use in production processes and consumer products. The stabilization of enzymes via small-molecular crosslinkers (INCYPRO), developed in the Grossmann lab, increases the robustness of enzymes towards conditions required for biotechnological applications. INCYPRO has the potential to improve current biotechnological processes and to allow completely new applications. As the method allows straight-forward and broad application, it is suitable for further valorization. Within this project, we will developed INCYPRO from its current method state into an validated technology and developed a market valorization strategy.