A Technology for the Generation of Stable Enzymes

Informations projet

INCYPRO

N° de convention de subvention: 839088

DOI

10.3030/839088

Projet clôturé

Date de signature de la CE 16 Janvier 2019

Date de début 1 Février 2019

Date de fin 31 Juillet 2020

Financé au titre de

• EXCELLENT SCIENCE - European Research Council (ERC)

Coût total

€ 150 000,00

Contribution de l’UE

€ 150 000,00

Coordonné par

STICHTING VU
Netherlands

Periodic Reporting for period 1 - INCYPRO (A Technology for the Generation of Stable Enzymes)

Période du rapport: 2019-02-01 au 2020-07-31

Résumé du contexte et des objectifs généraux du projet

The general awareness towards a sustainable life style is growing in society. This translates into a growing market for services and products that involve environment-friendly chemistry and material loops. Biotechnology will be one the key drivers when aiming for a circular economy, as it facilitates green chemistry and efficient recycling processes. A central component of most biotechnological processes are biocatalytic proteins (so-called enzymes). However, enzymes are intrinsically vulnerable to unnatural microenvironments hampering their wide-spread use in production processes and consumer products. The stabilization of enzymes via small-molecular crosslinkers (INCYPRO), developed in the Grossmann lab, increases the robustness of enzymes towards conditions required for biotechnological applications. INCYPRO has the potential to improve current biotechnological processes and to allow completely new applications. As the method allows straight-forward and broad application, it is suitable for further valorization. Within this project, we will developed INCYPRO from its current method state into an validated technology and developed a market valorization strategy.