Novel molecular targets against Mycobacteria
Antimicrobial resistance is increasing in prevalence affecting various bacteria, including Mycobacterium tuberculosis. Profoundly, this necessitates the development of novel effective drugs. The project deCrYPtion, funded by the EU, proposes to target the cytochrome P450 (CYP) family of proteins as a treatment strategy. The main goal is to provide physiological information on a number of CYPs that have yet to be functionally characterised. Scientists will analyse the CYPs encoded by Mycobacterium species and link their function to specific biological pathways. deCrYPtion results will lead to the identification of novel drug targets against the Mycobacterium genus.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health sciencesclinical medicinepneumologytuberculosis
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsantibiotics
- agricultural sciencesanimal and dairy sciencedomestic animalsanimal husbandry
- medical and health sciencesbasic medicinepharmacology and pharmacydrug resistanceantibiotic resistance