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Decrypting Mycobacterium cytochrome P450 (CYP) physiological functions by testing hypotheses emitted form large-scale comparative genomics analysis

Project description

Novel molecular targets against Mycobacteria

Antimicrobial resistance is increasing in prevalence affecting various bacteria, including Mycobacterium tuberculosis. Profoundly, this necessitates the development of novel effective drugs. The project deCrYPtion, funded by the EU, proposes to target the cytochrome P450 (CYP) family of proteins as a treatment strategy. The main goal is to provide physiological information on a number of CYPs that have yet to be functionally characterised. Scientists will analyse the CYPs encoded by Mycobacterium species and link their function to specific biological pathways. deCrYPtion results will lead to the identification of novel drug targets against the Mycobacterium genus.

Call for proposal

H2020-MSCA-IF-2018
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Coordinator

SWANSEA UNIVERSITY
Address
Singleton Park
SA2 8PP Swansea
United Kingdom

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Activity type
Higher or Secondary Education Establishments
EU contribution
€ 212 933,76