The objective of the DIFFUSION project was to develop an easy-to-use device to analyse diffusion processes within thin solvated films. Such a new analytical tool overcomes a current bottleneck in the development of functional coatings for a wide range of applications, from fundamental research in biophysics and microbiology to real-life applications in biomaterials and paints.
There is a broad need for the analysis and quantification of diffusion processes within thin polymer films; however, until now this has been challenging when the film is immersed in a solvent phase. The DIFFUSION technology overcomes this technological bottleneck. It was originally conceived during the ERC Starting Grant project JELLY, for the analysis of molecular diffusion in thin biopolymer hydrogel films. Quickly was it realised, however, that the technology adds value to many other areas of research and development in industry and academia – in material sciences and engineering, physics, chemistry and biology – wherever functional thin films/coatings are developed or used.
This project successfully developed a second-generation prototype device of the DIFFUSION technology. It comes as a modular add-on device that enhances the capabilities of the users' existing microscopy setups. Its cost-effectiveness and ease-of-use enhance the potential of rapid adoption by a wide range of users. The added value has been demonstrated with selected application examples covering target research and development areas, including biophysics and biology as well as polymer science and technology. A commercialisation plan has been developed, which identifies a partnership with industry is the most appropriate route to move the prototype to serial production and commercialisation.
Polymer coatings provide surfaces with new or enhanced functionalities. They are employed in a broad range of real-life applications including biomaterials, biosensors, nanomedicine, anti-fouling and anti-microbial coatings, food processing and paints. An important functional parameter of such coatings is how active substances (e.g. active synthetic molecules, proteins, nanoparticles) diffuse within them. Depending on the application, one may design ways to either enhance or delay such diffusion. The DIFFUSION technology provides the analytical means to monitor and fine-tune these processes.
