Skip to main content

Controllability of biological networks

Project description

New ways to control biological networks

Biological elements interact with others to form networks. The ability to control their dynamics is vital for scientific research, particularly for the pharmaceutical and medical industry. Despite advances in network science, the requisite computational approaches are still lacking. The NETCONTROLOGY project will explore how biological networks can be controlled with focus on two cutting-edge medical studies: to reprogram cancer networks (finding druggable vulnerabilities to improve anticancer therapeutics) and target the enzymatic sources of relevant oxidative stress to support neuroprotection in stroke. To do so, the project will develop nonlinear, quantitative and dynamic network models for biological networks with multiple regulatory mechanisms. It will also develop different measures to compare networks based on their controllability.

Call for proposal

H2020-MSCA-IF-2018
See other projects for this call

Funding Scheme

MSCA-IF-GF - Global Fellowships

Coordinator

UNIVERSITEIT MAASTRICHT
Address
Minderbroedersberg 4-6
6200 MD Maastricht
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 253 052,16

Partners (1)

NORTHEASTERN UNIVERSITY
United States
Address
Huntington Avenue 360 960 Rp
02115 Boston Ma
Activity type
Higher or Secondary Education Establishments