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Using the jellyfish Clytia hemisphaerica to explore the first steps of meiosis by live-imaging.

Project description

Visualisation of oogenesis

The EU-funded JOLI project will focus on oogenesis, the strictly regulated maturation and production of oocytes, which is a key process in development. Scientists will employ live imaging to monitor oogenesis in the hydrozoan Clytia hemisphaerica that possesses optically clear gonads. Visualisation of the entire process from stem cell to oocyte for the first time will provide important insight into the transition from the mitotic proliferation of germ cell precursors to meiosis. Moreover, JOLI will examine the role of specific molecules in oogenesis as well as in the process of meiosis and chromosome pairing. A better understanding of oogenesis will help determine the causes of female infertility.

Coordinator

COLLEGE DE FRANCE
Net EU contribution
€ 196 707,84
Address
Place Marcelin Berthelot 11
75005 Paris
France
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00