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Enzyme-powered DNA nanorobotic devices

Project description

Bringing biological robots a step closer to reality

Biocompatible microrobots capable of autonomous movement will find many biomedical applications, including drug delivery. Enzymes have emerged as attractive actuators of microrobot self-propulsion due to their ability to convert substrates into products. The EU-funded DNA-bots project is a nanotechnology-driven initiative that proposes to develop enzyme-powered nanorobots. These robots will further integrate DNA nanoswitches, sensors which undergo a predefined conformational change upon binding a target sequence. The idea is that these biocompatible and biodegradable nanorobotic devices will be able to respond specifically to certain stimuli with great efficacy and sensitivity and release their cargo.

Call for proposal

H2020-MSCA-IF-2018
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Coordinator

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Address
Via Cracovia 50
00133 Roma
Italy
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 183 473,28