Amsterdam Rheumatology Center for AutoImmune Diseases

Información del proyecto

ARCAID

Identificador del acuerdo de subvención: 847551

DOI

10.3030/847551

Proyecto cerrado

Fecha de la firma de la CE 4 Abril 2019

Fecha de inicio 1 Enero 2020

Fecha de finalización 31 Diciembre 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 339 200,00

Aportación de la UE

€ 2 169 600,00

Coordinado por

STICHTING AMSTERDAM UMC
Netherlands

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (1)

1ste Call: communication link to Euraxess

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement.

Publicaciones

Peer reviewed articles (37)

A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages.

Autores: Philippon EML, van Rooijen LJE, Khodadust F, van Hamburg JP, van der Laken CJ, Tas SW.
Publicado en: Front Immunol. 2023, Edición Jul 20;14:, 2023, Página(s) 1188835., ISSN 1664-3224
Editor: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1188835

In vitro immunity: an overview of immunocompetent organ-on-chip models.

Autores: Morrison AI, Sjoerds MJ, Vonk LA, Gibbs S, Koning JJ.
Publicado en: Front Immunol. 2024 May 21, Edición 15, 2024, Página(s) 1373186, ISSN 1664-3224
Editor: Frontiers Media S.A
DOI: 10.3389/fimmu.2024.1373186

An ultrasound negative for subclinical synovitis in arthralgia patients: is it helpful in identifying those not developing arthritis?

Autores: Rogier C, Frazzei G, Kortekaas MC, Verstappen M, Ohrndorf S, van Mulligen E, van Vollenhoven RF, van Schaardenburg D, de Jong PHP, van der Helm-van Mil AHM.
Publicado en: Rheumatology (Oxford)., Edición Nov 28;61(12), 2022, Página(s) 4892-4897, ISSN 1462-0332
Editor: Oxford University Press
DOI: 10.1093/rheumatology/keac239

A systematic literature review of preventive strategies in at-risk individuals

Autores: Frazzei, Giulia; Musters, Anne; de Vries, Niek; Tas, Sander W.; van Vollenhoven, Ronald F.
Publicado en: Frazzei , G , Musters , A , de Vries , N , Tas , S W & van Vollenhoven , R F 2022 , ' Prevention of rheumatoid arthritis : A systematic literature review of preventive strategies in at-risk individuals ' , Autoimmunity Reviews . https://doi.org/10.1016/j.autrev.2022.103217, Edición 2, 2023, ISSN 1568-9972
Editor: Elsevier BV
DOI: 10.1016/j.autrev.2022.103217

The effect of rituximab on patient reported outcomes in the preclinical phase of rheumatoid arthritis: 2 year data from the PRAIRI study

Autores: Giulia Frazzei, Sophie H M Cramer, Robert B M Landewé, Karen I Maijer, Danielle M Gerlag, Paul P Tak, Niek de Vries, Lisa G M van Baarsen, Ronald F van Vollenhoven, Sander W Tas
Publicado en: RMD Open, Edición 10, 2024, Página(s) e004622, ISSN 2056-5933
Editor: BMJ PUBLISHING GROUP
DOI: 10.1136/rmdopen-2024-004622

Targeting DORIS Remission and LLDAS in SLE: A Review.

Autores: Parra Sánchez AR, van Vollenhoven RF, Morand EF, Bruce IN, Kandane-Rathnayake R, Weiss G, Tummala R, Al-Mossawi H, Sorrentino A.
Publicado en: Rheumatol Ther, Edición Oct, 2023, ISSN 2198-6576
Editor: Springer Publishing
DOI: 10.1007/s40744-023-00601-w

Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition.

Autores: van den Ende T, Ezdoglian A, Baas LM, Bakker J, Lougheed SM, Harrasser M, Waasdorp C, van Berge Henegouwen MI, Hulshof MCCM, Haj Mohammad N, van Hillegersberg R, Mook S, van der Laken CJ, van Grieken NCT, Derks S, Bijlsma MF, van Laarhoven HWM, de Gruijl TD.
Publicado en: Oncoimmunology. 2023, Edición Jul 17;12(1), 2023, Página(s) 2233403, ISSN 2162-4011
Editor: Landes Bioscience
DOI: 10.1080/2162402x.2023.2233403

Web-based eHealth Clinical Decision Support System as a tool for the treat-to-target management of patients with systemic lupus erythematosus: development and initial usability evaluation.

Autores: Parra Sanchez AR, Grimberg MG, Hanssen M, Aben M, Jairth E, Dhoeme P, Tsang-A-Sjoe MWP, Voskuyl A, Jansen HJ, van Vollenhoven R.
Publicado en: BMJ Health Care Inform., Edición Sep;30(1), 2023, Página(s) e100811, ISSN 2632-1009
Editor: BMJ Journals
DOI: 10.1136/bmjhci-2023-100811

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

Autores: Chiara E Geyer, Hung-Jen Chen, Alexander P Bye, Xue D Manz, Denise Guerra, Tom G Caniels, Tom PL Bijl, Guillermo R Griffith, Willianne Hoepel, Steven W de Taeye, Jennifer Veth, Alexander PJ Vlaar, Amsterdam UMC COVID-19 Biobank, Gestur Vidarsson, Harm Jan Bogaard, Jurjan Aman, Jonathan M Gibbins, Marit J van Gils, Menno PJ de Winther, Jeroen den Dunnen
Publicado en: Life Science Alliance, Edición Sep 2023, 6 (11), 2023, Página(s) e202302106, ISSN 2575-1077
Editor: Rockefeller University Press
DOI: 10.26508/lsa.202302106

Understanding repertoire sequencing data through a multiscale computational model of the germinal center

Autores: Rodrigo García-Valiente; Elena Merino Tejero; Maria Stratigopoulou; Daria Balashova; Aldo Jongejan; Danial Lashgari; Aurélien Pélissier; Tom G. Caniels; Mathieu A. F. Claireaux; Anne Musters; Marit J. van Gils; María Rodríguez Martínez; Niek de Vries; Michael Meyer-Hermann; Jeroen E. J. Guikema; Huub Hoefsloot; Antoine H. C. van Kampen
Publicado en: systems biology and applications, volume 9(1), Edición 3, 2023, ISSN 2056-7189
Editor: United Kingdom Nature Publishing Group
DOI: 10.1038/s41540-023-00271-y

The Role of the Lymphatic System in the Pathogenesis and Treatment of Inflammatory Bowel Disease.

Autores: Nikolakis, D., de Voogd, F., Pruijt, M. J., Grootjans, J., van de Sande, M. G., & D'Haens, G. R.
Publicado en: International journal of molecular sciences, Edición 23(3),, 2022, Página(s) 1854., ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031854

Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy

Autores: Dimitrios Nikolakis; Panagiotis Garantziotis; George Sentis; Antonis Fanouriakis; George Bertsias; Eleni Frangou; Dionysis Nikolopoulos; Aggelos Banos; Dimitrios T Boumpas
Publicado en: BMC genomics 24(1), Edición 4, 2023, ISSN 1471-2164
Editor: BioMed Central
DOI: 10.1186/s12864-023-09275-8

The key role of the lymph node niche in the development of rheumatoid arthritis

Autores: Marina Jiménez-Martínez; Wendy Dankers; Lisa G.M. van Baarsen
Publicado en: Joint Bone Spine, Edición Volume 91, Edición 2, 2024, Página(s) 105661, ISSN 1297-319X
Editor: Elsevier Masson
DOI: 10.1016/j.jbspin.2023.105661

Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis

Autores: O'Byrne, Aoife M.; de Jong, Tineke A.; van Baarsen, Lisa G. M.
Publicado en: Frontiers in medicine rheumatology, Edición 1, 2022, ISSN 2296-858X
Editor: Frontiers
DOI: 10.3389/fmed.2021.820232

Synthesis and Characterization of Folic Acid-Conjugated Terbium Complexes as Luminescent Probes for Targeting Folate Receptor-Expressing Cells

Autores: Grace T. McMullon, Aiarpi Ezdoglian, Anna C. Booth, Pilar Jimenez-Royo, Philip S. Murphy, Gerrit Jansen, Conny J. van der Laken, Stephen Faulkner
Publicado en: Journal of Medicinal Chemistry, Edición 67, 2024, Página(s) 14062-14076, ISSN 0022-2623
Editor: American Chemical Society
DOI: 10.1021/acs.jmedchem.4c00919

Corrigendum: Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints

Autores: Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande, Lisa G. M. van Baarsen
Publicado en: Frontiers in Medicine, Edición 8, 2021, ISSN 2296-858X
Editor: Frontiers Media
DOI: 10.3389/fmed.2021.761410

Systematic evaluation of B-cell clonal family inference approaches

Autores: Daria Balashova, Barbera D. C. van Schaik, Maria Stratigopoulou, Jeroen E. J. Guikema, Tom G. Caniels, Mathieu Claireaux, Marit J. van Gils, Anne Musters, Dornatien C. Anang, Niek de Vries, Victor Greiff, Antoine H. C. van Kampen
Publicado en: BMC Immunology, Edición 25, 2024, ISSN 1471-2172
Editor: BioMed Central
DOI: 10.1186/s12865-024-00600-8

An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function

Autores: Andrew I. Morrison, Aleksandra M. Mikula, Sander W. Spiekstra, Michael de Kok, Alsya J. Affandi, Henk P. Roest, Luc J. W. van der Laan, Charlotte M. de Winde, Jasper J. Koning, Susan Gibbs, Reina E. Mebius
Publicado en: Tissue Engineering and Regenerative Medicine, Edición Dec 19, 2023, ISSN 1738-2696
Editor: Springer Science + Business Media
DOI: 10.1007/s13770-023-00609-x

Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis.

Autores: Khodadust F, Ezdoglian A, Steinz MM, van Beijnum JR, Zwezerijnen GJC, Jansen G, Tas SW, van der Laken CJ.
Publicado en: International Journal of Molecular Sciences. 2022, Edición 23(13), 2022, Página(s) 7071, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23137071

Lymph nodes as gatekeepers of autoimmune diseases

Autores: Aoife M O'Byrne, Lisa G M van Baarsen
Publicado en: RMD Open, Edición 10, 2024, Página(s) e004097, ISSN 2056-5933
Editor: BMJ Publishing Group
DOI: 10.1136/rmdopen-2024-004097

The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms

Autores: Frigerio, Sofía; Lartey, Dalia A.; D’Haens, Geert R.; Grootjans, Joep
Publicado en: Int. J. Mol. Sci., Edición 1, 2022, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222312739

Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis

Autores: Hammoura, Ihsan; Fiechter, Renee H.; Bryant, Shaughn H.; Westmoreland, Susan; Kingsbury, Gillian; Waegell, Wendy; Tas, Sander W.; Baeten, Dominique L.; van de Sande, Marleen G. H.; van Tok, Melissa N.; van Duivenvoorde, Leonie M.
Publicado en: Int. J. Mol. Sci., Edición 1, 2022, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23020859

Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins

Autores: Chiara Elisabeth Geyer, Lynn Mes, Melissa Newling, Jeroen den Dunnen, Willianne Hoepel
Publicado en: Cells, Edición 10/5, 2021, Página(s) 1175, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells10051175

B Lineage Cells in ANCA-Associated Vasculitis.

Autores: Ana Merino-Vico, Jan Piet van Hamburg and Sander W Tas.
Publicado en: Int. J. Mol. Sci., Edición 23(1), 2022, Página(s) 387, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23010387

Human lymph node fibroblastic reticular cells maintain heterogeneous characteristics in culture

Autores: Janna E.G. Roet, Andrew I. Morrison, Aleksandra M. Mikula, Michael de Kok, Daphne Panocha, Henk P. Roest, Luc J.W. van der Laan, Charlotte M. de Winde, Reina E. Mebius
Publicado en: iScience, Edición VOLUME 27, ISSUE 7, 2024, Página(s) 110179, ISSN 2589-0042
Editor: Cell Press (Elsevier)
DOI: 10.1016/j.isci.2024.110179

Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches.

Autores: Merino-Vico A, Frazzei G, van Hamburg JP, Tas SW.
Publicado en: Eur J Immunol, Edición Jan;53(1):, 2023, Página(s) e2149675, ISSN 0014-2980
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202149675

IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming

Autores: Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson, Jeroen den Dunnen
Publicado en: The Journal of Immunology, Edición 205/12, 2020, Página(s) 3400-3407, ISSN 0022-1767
Editor: American Association of Immunologists
DOI: 10.4049/jimmunol.2000263

Targeting NF-κB signaling in B cells as a potential new treatment modality for ANCA-associated vasculitis

Autores: Ana Merino-Vico; Jan Piet van Hamburg; Paul Tuijnenburg; Giulia Frazzei; Aram Al-Soudi; Carlo G. Bonasia; Boy Helder; Abraham Rutgers; Wayel H. Abdulahad; Coen A. Stegeman; Jan-Stephan Sanders; Laura Bergamaschi; Paul A. Lyons; Theo Bijma; Laura van Keep; Kirsten Wesenhagen; Aldo Jongejan; Henric Olsson; Niek de Vries; Taco W. Kuijpers; Peter Heeringa; Sander W. Tas
Publicado en: Journal of Autoimmunity vol 142, 2024, Página(s) 103133, ISSN 0896-8411
Editor: Academic Press
DOI: 10.1016/j.jaut.2023.103133

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Autores: Mads Delbo Larsen, Erik L. de Graaf, Myrthe E. Sonneveld, H. Rosina Plomp, Jan Nouta, Willianne Hoepel, Hung-Jen Chen, Federica Linty, Remco Visser, Maximilian Brinkhaus, Tonći Šuštić, Steven W. de Taeye, Arthur E. H. Bentlage, Suvi Toivonen, Carolien A. M. Koeleman, Susanna Sainio, Neeltje A. Kootstra, Philip J. M. Brouwer, Chiara Elisabeth Geyer, Ninotska I. L. Derksen, Gertjan Wolbink, Menn
Publicado en: Science, Edición 371/6532, 2021, Página(s) eabc8378, ISSN 0036-8075
Editor: American Association for the Advancement of Science
DOI: 10.1126/science.abc8378

Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis

Autores: Steinz MM, Ezdoglian A, Khodadust F, Molthoff CFM, Srinivasarao M, Low PS, Zwezerijnen GJC, Yaqub M, Beaino W, Windhorst AD, Tas SW, Jansen G, van der Laken CJ.
Publicado en: Front Immunol. 2022, Edición Feb 2;13:, 2022, Página(s) 819163., ISSN 1664-3224
Editor: Frontiers SA
DOI: 10.3389/fimmu.2022.819163

High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Autores: Willianne Hoepel, Hung-Jen Chen, Chiara E. Geyer, Sona Allahverdiyeva, Xue D. Manz, Steven W. de Taeye, Jurjan Aman, Lynn Mes, Maurice Steenhuis, Guillermo R. Griffith, Peter I. Bonta, Philip J.M. Brouwer, Tom G. Caniels, Karlijn van der Straten, Korneliusz Golebski, René E. Jonkers, Mads D. Larsen, Federica Linty, Jan Nouta, Cindy P.A.A. van Roomen, Frank E.H.P. van Baarle, Cornelis M. van Drune
Publicado en: Science Translational Medicine, Edición 13/596, 2021, Página(s) eabf8654, ISSN 1946-6234
Editor: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abf8654

Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells

Autores: Melis Asal; Mila Rep; Hetty J. Bontkes; Sandra J. van Vliet; Reina E. Mebius; Susan Gibbs
Publicado en: Tissue Engineering and Regenerative Medicine, Edición 21, 369–377, 2024, ISSN 2212-5469
Editor: Springer Link
DOI: 10.1007/s13770-023-00600-6

Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints.

Autores: Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande and Lisa G. M. van Baarsen.
Publicado en: Frontiers in Medicine, Edición 8, 2021, Página(s) 1270, ISSN 2296-858X
Editor: Frontiers Media SA
DOI: 10.3389/fmed.2021.711823

Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

Autores: Parra Sánchez, Agner R.; Voskuyl, Alexandre E.; van Vollenhoven, Ronald F.
Publicado en: Nature reviews rheumatology, Edición 1, 2022, ISSN 1759-4790
Editor: Nature Publishing Group
DOI: 10.1038/s41584-021-00739-3

ENCORE. A practical implementation to improve reproducibility and transparency of computational research.

Autores: Antoine van Kampen, Utkarsh Mahamune, Aldo Jongejan, Barbera van Schaik, Dasha Balashova, Danial Lashgari, Mia Pras-Raves, Eric Wever, Adrie Dane, Rodrigo Garcia Valiente, Perry Moerland
Publicado en: Nature Communications, Edición 15, 2024, Página(s) 8117, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.31222/osf.io/m9yqz

Preclinical Autoimmune Disease: a Comparison of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Multiple Sclerosis and Type 1 Diabetes

Autores: Giulia Frazzei, Ronald F van Vollenhoven, Brigit A de Jong, Sarah E Siegelaar, Dirkjan van Schaardenburg
Publicado en: Front Immunol., Edición Jun 30;13, 2022, Página(s) 899372, ISSN 1664-3224
Editor: Frontiers Media S.A
DOI: 10.3389/fimmu.2022.899372

Reactive Protein Controls IL-23 Production by Human Monocytes.

Autores: Geyer, C.E.; Newling, M.; Sritharan, L.; Griffith, G.R.; Chen, H.-J.; Baeten, D.L.P.; den Dunnen, J. C-
Publicado en: Int. J. Mol. Sci., Edición 22, 2021, Página(s) 11638, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222111638