Amsterdam Rheumatology Center for AutoImmune Diseases

Informazioni relative al progetto

ARCAID

ID dell’accordo di sovvenzione: 847551

DOI

10.3030/847551

Progetto chiuso

Data della firma CE 4 Aprile 2019

Data di avvio 1 Gennaio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 339 200,00

Contributo UE

€ 2 169 600,00

Coordinato da

STICHTING AMSTERDAM UMC
Netherlands

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (1)

1ste Call: communication link to Euraxess

Inform the Project Officer on publishing each call for proposals, by sending the link to the Euraxess website and a screen shot of the related call announcement.

Pubblicazioni

Peer reviewed articles (37)

A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages.

Autori: Philippon EML, van Rooijen LJE, Khodadust F, van Hamburg JP, van der Laken CJ, Tas SW.
Pubblicato in: Front Immunol. 2023, Numero Jul 20;14:, 2023, Pagina/e 1188835., ISSN 1664-3224
Editore: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1188835

In vitro immunity: an overview of immunocompetent organ-on-chip models.

Autori: Morrison AI, Sjoerds MJ, Vonk LA, Gibbs S, Koning JJ.
Pubblicato in: Front Immunol. 2024 May 21, Numero 15, 2024, Pagina/e 1373186, ISSN 1664-3224
Editore: Frontiers Media S.A
DOI: 10.3389/fimmu.2024.1373186

An ultrasound negative for subclinical synovitis in arthralgia patients: is it helpful in identifying those not developing arthritis?

Autori: Rogier C, Frazzei G, Kortekaas MC, Verstappen M, Ohrndorf S, van Mulligen E, van Vollenhoven RF, van Schaardenburg D, de Jong PHP, van der Helm-van Mil AHM.
Pubblicato in: Rheumatology (Oxford)., Numero Nov 28;61(12), 2022, Pagina/e 4892-4897, ISSN 1462-0332
Editore: Oxford University Press
DOI: 10.1093/rheumatology/keac239

A systematic literature review of preventive strategies in at-risk individuals

Autori: Frazzei, Giulia; Musters, Anne; de Vries, Niek; Tas, Sander W.; van Vollenhoven, Ronald F.
Pubblicato in: Frazzei , G , Musters , A , de Vries , N , Tas , S W & van Vollenhoven , R F 2022 , ' Prevention of rheumatoid arthritis : A systematic literature review of preventive strategies in at-risk individuals ' , Autoimmunity Reviews . https://doi.org/10.1016/j.autrev.2022.103217, Numero 2, 2023, ISSN 1568-9972
Editore: Elsevier BV
DOI: 10.1016/j.autrev.2022.103217

The effect of rituximab on patient reported outcomes in the preclinical phase of rheumatoid arthritis: 2 year data from the PRAIRI study

Autori: Giulia Frazzei, Sophie H M Cramer, Robert B M Landewé, Karen I Maijer, Danielle M Gerlag, Paul P Tak, Niek de Vries, Lisa G M van Baarsen, Ronald F van Vollenhoven, Sander W Tas
Pubblicato in: RMD Open, Numero 10, 2024, Pagina/e e004622, ISSN 2056-5933
Editore: BMJ PUBLISHING GROUP
DOI: 10.1136/rmdopen-2024-004622

Targeting DORIS Remission and LLDAS in SLE: A Review.

Autori: Parra Sánchez AR, van Vollenhoven RF, Morand EF, Bruce IN, Kandane-Rathnayake R, Weiss G, Tummala R, Al-Mossawi H, Sorrentino A.
Pubblicato in: Rheumatol Ther, Numero Oct, 2023, ISSN 2198-6576
Editore: Springer Publishing
DOI: 10.1007/s40744-023-00601-w

Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibition.

Autori: van den Ende T, Ezdoglian A, Baas LM, Bakker J, Lougheed SM, Harrasser M, Waasdorp C, van Berge Henegouwen MI, Hulshof MCCM, Haj Mohammad N, van Hillegersberg R, Mook S, van der Laken CJ, van Grieken NCT, Derks S, Bijlsma MF, van Laarhoven HWM, de Gruijl TD.
Pubblicato in: Oncoimmunology. 2023, Numero Jul 17;12(1), 2023, Pagina/e 2233403, ISSN 2162-4011
Editore: Landes Bioscience
DOI: 10.1080/2162402x.2023.2233403

Web-based eHealth Clinical Decision Support System as a tool for the treat-to-target management of patients with systemic lupus erythematosus: development and initial usability evaluation.

Autori: Parra Sanchez AR, Grimberg MG, Hanssen M, Aben M, Jairth E, Dhoeme P, Tsang-A-Sjoe MWP, Voskuyl A, Jansen HJ, van Vollenhoven R.
Pubblicato in: BMJ Health Care Inform., Numero Sep;30(1), 2023, Pagina/e e100811, ISSN 2632-1009
Editore: BMJ Journals
DOI: 10.1136/bmjhci-2023-100811

Identification of new drugs to counteract anti-spike IgG-induced hyperinflammation in severe COVID-19

Autori: Chiara E Geyer, Hung-Jen Chen, Alexander P Bye, Xue D Manz, Denise Guerra, Tom G Caniels, Tom PL Bijl, Guillermo R Griffith, Willianne Hoepel, Steven W de Taeye, Jennifer Veth, Alexander PJ Vlaar, Amsterdam UMC COVID-19 Biobank, Gestur Vidarsson, Harm Jan Bogaard, Jurjan Aman, Jonathan M Gibbins, Marit J van Gils, Menno PJ de Winther, Jeroen den Dunnen
Pubblicato in: Life Science Alliance, Numero Sep 2023, 6 (11), 2023, Pagina/e e202302106, ISSN 2575-1077
Editore: Rockefeller University Press
DOI: 10.26508/lsa.202302106

Understanding repertoire sequencing data through a multiscale computational model of the germinal center

Autori: Rodrigo García-Valiente; Elena Merino Tejero; Maria Stratigopoulou; Daria Balashova; Aldo Jongejan; Danial Lashgari; Aurélien Pélissier; Tom G. Caniels; Mathieu A. F. Claireaux; Anne Musters; Marit J. van Gils; María Rodríguez Martínez; Niek de Vries; Michael Meyer-Hermann; Jeroen E. J. Guikema; Huub Hoefsloot; Antoine H. C. van Kampen
Pubblicato in: systems biology and applications, volume 9(1), Numero 3, 2023, ISSN 2056-7189
Editore: United Kingdom Nature Publishing Group
DOI: 10.1038/s41540-023-00271-y

The Role of the Lymphatic System in the Pathogenesis and Treatment of Inflammatory Bowel Disease.

Autori: Nikolakis, D., de Voogd, F., Pruijt, M. J., Grootjans, J., van de Sande, M. G., & D'Haens, G. R.
Pubblicato in: International journal of molecular sciences, Numero 23(3),, 2022, Pagina/e 1854., ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031854

Restoration of aberrant gene expression of monocytes in systemic lupus erythematosus via a combined transcriptome-reversal and network-based drug repurposing strategy

Autori: Dimitrios Nikolakis; Panagiotis Garantziotis; George Sentis; Antonis Fanouriakis; George Bertsias; Eleni Frangou; Dionysis Nikolopoulos; Aggelos Banos; Dimitrios T Boumpas
Pubblicato in: BMC genomics 24(1), Numero 4, 2023, ISSN 1471-2164
Editore: BioMed Central
DOI: 10.1186/s12864-023-09275-8

The key role of the lymph node niche in the development of rheumatoid arthritis

Autori: Marina Jiménez-Martínez; Wendy Dankers; Lisa G.M. van Baarsen
Pubblicato in: Joint Bone Spine, Numero Volume 91, Numero 2, 2024, Pagina/e 105661, ISSN 1297-319X
Editore: Elsevier Masson
DOI: 10.1016/j.jbspin.2023.105661

Bridging Insights From Lymph Node and Synovium Studies in Early Rheumatoid Arthritis

Autori: O'Byrne, Aoife M.; de Jong, Tineke A.; van Baarsen, Lisa G. M.
Pubblicato in: Frontiers in medicine rheumatology, Numero 1, 2022, ISSN 2296-858X
Editore: Frontiers
DOI: 10.3389/fmed.2021.820232

Synthesis and Characterization of Folic Acid-Conjugated Terbium Complexes as Luminescent Probes for Targeting Folate Receptor-Expressing Cells

Autori: Grace T. McMullon, Aiarpi Ezdoglian, Anna C. Booth, Pilar Jimenez-Royo, Philip S. Murphy, Gerrit Jansen, Conny J. van der Laken, Stephen Faulkner
Pubblicato in: Journal of Medicinal Chemistry, Numero 67, 2024, Pagina/e 14062-14076, ISSN 0022-2623
Editore: American Chemical Society
DOI: 10.1021/acs.jmedchem.4c00919

Corrigendum: Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints

Autori: Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande, Lisa G. M. van Baarsen
Pubblicato in: Frontiers in Medicine, Numero 8, 2021, ISSN 2296-858X
Editore: Frontiers Media
DOI: 10.3389/fmed.2021.761410

Systematic evaluation of B-cell clonal family inference approaches

Autori: Daria Balashova, Barbera D. C. van Schaik, Maria Stratigopoulou, Jeroen E. J. Guikema, Tom G. Caniels, Mathieu Claireaux, Marit J. van Gils, Anne Musters, Dornatien C. Anang, Niek de Vries, Victor Greiff, Antoine H. C. van Kampen
Pubblicato in: BMC Immunology, Numero 25, 2024, ISSN 1471-2172
Editore: BioMed Central
DOI: 10.1186/s12865-024-00600-8

An Organotypic Human Lymph Node Model Reveals the Importance of Fibroblastic Reticular Cells for Dendritic Cell Function

Autori: Andrew I. Morrison, Aleksandra M. Mikula, Sander W. Spiekstra, Michael de Kok, Alsya J. Affandi, Henk P. Roest, Luc J. W. van der Laan, Charlotte M. de Winde, Jasper J. Koning, Susan Gibbs, Reina E. Mebius
Pubblicato in: Tissue Engineering and Regenerative Medicine, Numero Dec 19, 2023, ISSN 1738-2696
Editore: Springer Science + Business Media
DOI: 10.1007/s13770-023-00609-x

Systematic Review: Targeted Molecular Imaging of Angiogenesis and Its Mediators in Rheumatoid Arthritis.

Autori: Khodadust F, Ezdoglian A, Steinz MM, van Beijnum JR, Zwezerijnen GJC, Jansen G, Tas SW, van der Laken CJ.
Pubblicato in: International Journal of Molecular Sciences. 2022, Numero 23(13), 2022, Pagina/e 7071, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23137071

Lymph nodes as gatekeepers of autoimmune diseases

Autori: Aoife M O'Byrne, Lisa G M van Baarsen
Pubblicato in: RMD Open, Numero 10, 2024, Pagina/e e004097, ISSN 2056-5933
Editore: BMJ Publishing Group
DOI: 10.1136/rmdopen-2024-004097

The Role of the Immune System in IBD-Associated Colorectal Cancer: From Pro to Anti-Tumorigenic Mechanisms

Autori: Frigerio, Sofía; Lartey, Dalia A.; D’Haens, Geert R.; Grootjans, Joep
Pubblicato in: Int. J. Mol. Sci., Numero 1, 2022, ISSN 2078-2489
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222312739

Dual Blockade of TNF and IL-17A Inhibits Inflammation and Structural Damage in a Rat Model of Spondyloarthritis

Autori: Hammoura, Ihsan; Fiechter, Renee H.; Bryant, Shaughn H.; Westmoreland, Susan; Kingsbury, Gillian; Waegell, Wendy; Tas, Sander W.; Baeten, Dominique L.; van de Sande, Marleen G. H.; van Tok, Melissa N.; van Duivenvoorde, Leonie M.
Pubblicato in: Int. J. Mol. Sci., Numero 1, 2022, ISSN 2078-2489
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23020859

Physiological and Pathological Inflammation Induced by Antibodies and Pentraxins

Autori: Chiara Elisabeth Geyer, Lynn Mes, Melissa Newling, Jeroen den Dunnen, Willianne Hoepel
Pubblicato in: Cells, Numero 10/5, 2021, Pagina/e 1175, ISSN 2073-4409
Editore: MDPI
DOI: 10.3390/cells10051175

B Lineage Cells in ANCA-Associated Vasculitis.

Autori: Ana Merino-Vico, Jan Piet van Hamburg and Sander W Tas.
Pubblicato in: Int. J. Mol. Sci., Numero 23(1), 2022, Pagina/e 387, ISSN 2078-2489
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23010387

Human lymph node fibroblastic reticular cells maintain heterogeneous characteristics in culture

Autori: Janna E.G. Roet, Andrew I. Morrison, Aleksandra M. Mikula, Michael de Kok, Daphne Panocha, Henk P. Roest, Luc J.W. van der Laan, Charlotte M. de Winde, Reina E. Mebius
Pubblicato in: iScience, Numero VOLUME 27, ISSUE 7, 2024, Pagina/e 110179, ISSN 2589-0042
Editore: Cell Press (Elsevier)
DOI: 10.1016/j.isci.2024.110179

Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches.

Autori: Merino-Vico A, Frazzei G, van Hamburg JP, Tas SW.
Pubblicato in: Eur J Immunol, Numero Jan;53(1):, 2023, Pagina/e e2149675, ISSN 0014-2980
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202149675

IgG Subclasses Shape Cytokine Responses by Human Myeloid Immune Cells through Differential Metabolic Reprogramming

Autori: Willianne Hoepel, Sona Allahverdiyeva, Haneen Harbiye, Steven W. de Taeye, Alwin J. van der Ham, Leonie de Boer, Sebastiaan A. J. Zaat, Michel van Weeghel, Dominique L. P. Baeten, Riekelt H. Houtkooper, Bart Everts, Gestur Vidarsson, Jeroen den Dunnen
Pubblicato in: The Journal of Immunology, Numero 205/12, 2020, Pagina/e 3400-3407, ISSN 0022-1767
Editore: American Association of Immunologists
DOI: 10.4049/jimmunol.2000263

Targeting NF-κB signaling in B cells as a potential new treatment modality for ANCA-associated vasculitis

Autori: Ana Merino-Vico; Jan Piet van Hamburg; Paul Tuijnenburg; Giulia Frazzei; Aram Al-Soudi; Carlo G. Bonasia; Boy Helder; Abraham Rutgers; Wayel H. Abdulahad; Coen A. Stegeman; Jan-Stephan Sanders; Laura Bergamaschi; Paul A. Lyons; Theo Bijma; Laura van Keep; Kirsten Wesenhagen; Aldo Jongejan; Henric Olsson; Niek de Vries; Taco W. Kuijpers; Peter Heeringa; Sander W. Tas
Pubblicato in: Journal of Autoimmunity vol 142, 2024, Pagina/e 103133, ISSN 0896-8411
Editore: Academic Press
DOI: 10.1016/j.jaut.2023.103133

Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity

Autori: Mads Delbo Larsen, Erik L. de Graaf, Myrthe E. Sonneveld, H. Rosina Plomp, Jan Nouta, Willianne Hoepel, Hung-Jen Chen, Federica Linty, Remco Visser, Maximilian Brinkhaus, Tonći Šuštić, Steven W. de Taeye, Arthur E. H. Bentlage, Suvi Toivonen, Carolien A. M. Koeleman, Susanna Sainio, Neeltje A. Kootstra, Philip J. M. Brouwer, Chiara Elisabeth Geyer, Ninotska I. L. Derksen, Gertjan Wolbink, Menn
Pubblicato in: Science, Numero 371/6532, 2021, Pagina/e eabc8378, ISSN 0036-8075
Editore: American Association for the Advancement of Science
DOI: 10.1126/science.abc8378

Folate Receptor Beta for Macrophage Imaging in Rheumatoid Arthritis

Autori: Steinz MM, Ezdoglian A, Khodadust F, Molthoff CFM, Srinivasarao M, Low PS, Zwezerijnen GJC, Yaqub M, Beaino W, Windhorst AD, Tas SW, Jansen G, van der Laken CJ.
Pubblicato in: Front Immunol. 2022, Numero Feb 2;13:, 2022, Pagina/e 819163., ISSN 1664-3224
Editore: Frontiers SA
DOI: 10.3389/fimmu.2022.819163

High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages

Autori: Willianne Hoepel, Hung-Jen Chen, Chiara E. Geyer, Sona Allahverdiyeva, Xue D. Manz, Steven W. de Taeye, Jurjan Aman, Lynn Mes, Maurice Steenhuis, Guillermo R. Griffith, Peter I. Bonta, Philip J.M. Brouwer, Tom G. Caniels, Karlijn van der Straten, Korneliusz Golebski, René E. Jonkers, Mads D. Larsen, Federica Linty, Jan Nouta, Cindy P.A.A. van Roomen, Frank E.H.P. van Baarle, Cornelis M. van Drune
Pubblicato in: Science Translational Medicine, Numero 13/596, 2021, Pagina/e eabf8654, ISSN 1946-6234
Editore: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abf8654

Towards Full Thickness Small Intestinal Models: Incorporation of Stromal Cells

Autori: Melis Asal; Mila Rep; Hetty J. Bontkes; Sandra J. van Vliet; Reina E. Mebius; Susan Gibbs
Pubblicato in: Tissue Engineering and Regenerative Medicine, Numero 21, 369–377, 2024, ISSN 2212-5469
Editore: Springer Link
DOI: 10.1007/s13770-023-00600-6

Translational Research Studies Unraveling the Origins of Psoriatic Arthritis: Moving Beyond Skin and Joints.

Autori: Janne W. Bolt, Chaja M. J. van Ansenwoude, Ihsan Hammoura, Marleen G. van de Sande and Lisa G. M. van Baarsen.
Pubblicato in: Frontiers in Medicine, Numero 8, 2021, Pagina/e 1270, ISSN 2296-858X
Editore: Frontiers Media SA
DOI: 10.3389/fmed.2021.711823

Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

Autori: Parra Sánchez, Agner R.; Voskuyl, Alexandre E.; van Vollenhoven, Ronald F.
Pubblicato in: Nature reviews rheumatology, Numero 1, 2022, ISSN 1759-4790
Editore: Nature Publishing Group
DOI: 10.1038/s41584-021-00739-3

ENCORE. A practical implementation to improve reproducibility and transparency of computational research.

Autori: Antoine van Kampen, Utkarsh Mahamune, Aldo Jongejan, Barbera van Schaik, Dasha Balashova, Danial Lashgari, Mia Pras-Raves, Eric Wever, Adrie Dane, Rodrigo Garcia Valiente, Perry Moerland
Pubblicato in: Nature Communications, Numero 15, 2024, Pagina/e 8117, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.31222/osf.io/m9yqz

Preclinical Autoimmune Disease: a Comparison of Rheumatoid Arthritis, Systemic Lupus Erythematosus, Multiple Sclerosis and Type 1 Diabetes

Autori: Giulia Frazzei, Ronald F van Vollenhoven, Brigit A de Jong, Sarah E Siegelaar, Dirkjan van Schaardenburg
Pubblicato in: Front Immunol., Numero Jun 30;13, 2022, Pagina/e 899372, ISSN 1664-3224
Editore: Frontiers Media S.A
DOI: 10.3389/fimmu.2022.899372

Reactive Protein Controls IL-23 Production by Human Monocytes.

Autori: Geyer, C.E.; Newling, M.; Sritharan, L.; Griffith, G.R.; Chen, H.-J.; Baeten, D.L.P.; den Dunnen, J. C-
Pubblicato in: Int. J. Mol. Sci., Numero 22, 2021, Pagina/e 11638, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms222111638