The origin and evolution of Life in the universe

Resultado final

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Publicaciones

Quorum sensing communication between lipid-based artificial cells

Autores: Antoni Llopis-Lorente; Bastiaan C. Buddingh'; R. Martínez-Máñez; Jan C. M. van Hest; Loai K. E. Abdelmohsen
Publicado en: Chemical Communications, 59(5), 579 - 582. Royal Society of Chemistry, Edición Volume 59, Edición 5, 2022, Página(s) 579 - 582, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc05367e

An X-ray spectroscopy study of structural stability of superhydrogenated pyrene derivatives

Autores: Yining Huo, Mónica K Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: Monthly Notices of the Royal Astronomical Society, Edición 523, 2023, Página(s) 865-875, ISSN 0035-8711
Editor: Blackwell Publishing Inc.
DOI: 10.1093/mnras/stad1341

Enantioselective Self-Replicators

Autores: Shuo Yang, Yannick Geiger, Marc Geerts, Marcel J. Eleveld, Armin Kiani, Sijbren Otto
Publicado en: Journal of the American Chemical Society, Edición 145, 2023, Página(s) 16889-16898, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c05472

Impact of ancestral sequence reconstruction on mechanistic and structural enzymology

Autores: Callum R. Nicoll, Marta Massari, Marco W. Fraaije, Maria Laura Mascotti, Andrea Mattevi
Publicado en: Current Opinion in Structural Biology, Edición 82, 2024, Página(s) 102669, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2023.102669

On the diversity of F 420 ‐dependent oxidoreductases: A sequence‐ and structure‐based classification

Autores: María Laura Mascotti, Maximiliano Juri Ayub, Marco W. Fraaije
Publicado en: Proteins: Structure, Function, and Bioinformatics, Edición 89/11, 2021, Página(s) 1497-1507, ISSN 0887-3585
Editor: Wiley-Liss Inc
DOI: 10.1002/prot.26170

Role of Curvature-Sensing Proteins in the Uptake of Nanoparticles with Different Mechanical Properties

Autores: Daphne Montizaan, Catherine Saunders, Keni Yang, Sajitha Sasidharan, Sourav Maity, Catharina Reker-Smit, Marc C.A. Stuart, Costanza Montis, Debora Berti, Wouter H. Roos, Anna Salvati
Publicado en: Small, Edición vol 19 , issue 39, 2023, Página(s) 2303267, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202303267

Mutational and structural analysis of an ancestral fungal dye-decolorizing peroxidase

Autores: Ulises A. Zitare; Ulises A. Zitare; Mohamed H. Habib; Mohamed H. Habib; Henriëtte J. Rozeboom; María Laura Mascotti; María Laura Mascotti; Smilja Todorovic; Marco W. Fraaije
Publicado en: The FEBS Journal, Edición VOLUME=288;ISSUE=11, 2020, Página(s) TARTPAGE=3602;ENDPAGE=3618, ISSN 1742-464X
Editor: Blackwell Publishing Inc.
DOI: 10.5281/zenodo.7190636

Achieving Control in Micro-/Nanomotor Mobility

Autores: Alexander D. Fusi, Yudong Li, Dr. A. Llopis-Lorente, Dr. Tania Patiño, Prof. Dr. Jan C. M. van Hest, Dr. Loai K. E. A. Abdelmohsen
Publicado en: Angewandte ChemieBron:Wiley Online Library: Complete Journals, Edición volume 135, issue 5, 2023, ISSN 0044-8249
Editor: John Wiley and Sons,
DOI: 10.1002/ange.202214754

Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

Autores: Gobert Heesink, Mirjam J. Marseille, Mohammad A. A. Fakhree, Mark D. Driver, Kirsten A. van Leijenhorst-Groener, Patrick R. Onck, Christian Blum, Mireille M.A.E. Claessens
Publicado en: Biomacromolecules, Edición 24, 2023, Página(s) 3680-3688, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00404

A comparative laboratory study of soft X-ray-induced ionization and fragmentation of five small PAH cations

Autores: Yining Huo, Mónica K. Espinoza Cangahuala, Vicente Zamudio-bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J. Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: The European Physical Journal D, Edición volume 77, issue 10, 2023, Página(s) 11 pages, ISSN 1434-6060
Editor: Springer Verlag
DOI: 10.1140/epjd/s10053-023-00763-w

Non-Linear Effects in Asymmetric Catalysis: Impact of Catalyst Precipitation

Autores: Yannick Geiger, Stéphane Bellemin-Laponnaz
Publicado en: ChemCatChem, Edición vol 14, issue 9, 2022, Página(s) e202200165, pages 7, ISSN 1867-3880
Editor: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202200165

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Autores: Vakil Takhaveev; Serdar Özsezen; Edward N. Smith; Andre Zylstra; Marten L. Chaillet; Haoqi Chen; Alexandros Papagiannakis; Andreas Milias-Argeitis; Matthias Heinemann
Publicado en: Nature Metabolism, Edición volume 5, issue 2, 2023, Página(s) 294-313, ISSN 2522-5812
Editor: Nature Research
DOI: 10.3929/ethz-b-000601600

Bacterial multi-solute transporters

Autores: D J Slotboom*, T W Ettema, M Nijland, C Thangaratnarajah
Publicado en: FEBS Letters, Edición vol 594, issue 23, 2020, Página(s) 3898-3907, ISSN 1742-4658
Editor: Wiley
DOI: 10.1002/1873-3468.13912

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

Autores: Apirat Chaikuad, Chancievan Thangaratnarajah, Frank von Delft, Alex N Bullock
Publicado en: Scientific Reports, Edición vol 9, issue 1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-54830-7

Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides

Autores: Xiao‐Bing Chen; Damián Padín; Charlotte N. Stindt; Ben L. Feringa
Publicado en: Angewandte Chemie (International ed. in English, Edición vol 62, number 33, 2023, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/ange.202307450

Temporal segregation of biosynthetic processes is responsible for metabolic oscillations during the budding yeast cell cycle

Autores: Vakil Takhaveev, Serdar Özsezen, Edward N. Smith, Andre Zylstra, Marten L. Chaillet, Haoqi Chen, Alexandros Papagiannakis, Andreas Milias-Argeitis, Matthias Heinemann
Publicado en: Nature Metabolism, Edición 5, 2023, Página(s) 294-313, ISSN 2522-5812
Editor: Springer
DOI: 10.1038/s42255-023-00741-x

Vanillyl alcohol oxidase from Diplodia corticola: Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives

Autores: Daniel Eggerichs, Nils Weindorf, Maria Laura Mascotti, Natalie Welzel, Marco W. Fraaije, Dirk Tischler
Publicado en: Journal of Biological Chemistry, Edición 299, 2024, Página(s) 104898, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.104898

Asymmetric Synthesis of Chiral‐at‐P Alkenylphosphonamidates through Nickel‐Catalyzed C−P Coupling of Phosphoramidites and Alkenyl Halides

Autores: Xiao‐Bing Chen, Damián Padín, Charlotte N. Stindt, Ben L. Feringa
Publicado en: Angewandte Chemie International Edition, Edición 62, 2023, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202307450

Bacterial multi‐solute transporters

Autores: Dirk J. Slotboom, Thijs W. Ettema, Mark Nijland, Chancievan Thangaratnarajah
Publicado en: FEBS Letters, Edición 594, 2023, Página(s) 3898-3907, ISSN 0014-5793
Editor: Elsevier BV
DOI: 10.1002/1873-3468.13912

Metabolic dynamics during the cell cycle

Autores: Andre Zylstra, Matthias Heinemann
Publicado en: Current Opinion in Systems Biology, Edición 24523100, 2022, ISSN 2452-3100
Editor: Elsevier
DOI: 10.1016/j.coisb.2022.100415

Observation of Hyperpositive Non-Linear Effect in Asymmetric Organozinc Alkylation in Presence of N-Pyrrolidinyl Norephedrine

Autores: Thibault Thierry, Yannick Geiger, Stéphane Bellemin-Laponnaz
Publicado en: Molecules, Edición vol 27, issue12, 2022, Página(s) 9 pages, ISSN 1431-5157
Editor: MDPI AG
DOI: 10.3390/molecules27123780

Mutational and structural analysis of an ancestral fungal dye‐decolorizing peroxidase

Autores: Ulises A. Zitare, Mohamed H. Habib, Henriette Rozeboom, Maria L. Mascotti, Smilja Todorovic, Marco W. Fraaije
Publicado en: The FEBS Journal, 2020, ISSN 1742-464X
Editor: Blackwell Publishing Inc.
DOI: 10.1111/febs.15687

Senescence in yeast is associated with amplified linear fragments of chromosome XII rather than ribosomal DNA circle accumulation

Autores: Andre Zylstra, Hanane Hadj-Moussa, Dorottya Horkai, Alex J. Whale, Baptiste Piguet, Jonathan Houseley
Publicado en: PLoS Biology, Edición volume 21, issue 8, 2023, Página(s) 42 pages, ISSN 1544-9173
Editor: Public Library of Science
DOI: 10.1371/journal.pbio.3002250

A target list for searching for habitable exomoons

Autores: Vera Dobos, András Haris, Inga E. E. Kamp, Floris F. S. van der Tak
Publicado en: Monthly Notices of the Royal Astronomical Society, Edición 13652966, 2022, Página(s) 5290–5298, ISSN 1365-2966
Editor: Oxford University Press
DOI: 10.1093/mnras/stac1180

Endocytosis-like DNA uptake by cell wall-deficient bacteria

Autores: Renée Kapteijn, Shraddha Shitut, Dennis Aschmann, Le Zhang, Marit de Beer, Deniz Daviran, Rona Roverts, Anat Akiva, Gilles P. van Wezel, Alexander Kros & Dennis Claessen
Publicado en: Nature Communications, Edición volume 13, issue 1, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-33054-w

Engineering chemical communication between micro/nanosystems

Autores: Beatriz de Luis, Antoni Llopis-Lorente, Félix Sancenón and Ramón Martínez-Máñez
Publicado en: Chemical Society Reviews, Edición 03060012, 2021, Página(s) 8829-8856, ISSN 0306-0012
Editor: Royal Society of Chemistry
DOI: 10.1039/d0cs01048k

Author Correction: CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Autores: László Mózsik, Mirthe Hoekzema, Niels A.W. de Kok, Roel A.L. Bovenberg, Yvonne Nygård, Arnold J.M. Driessen
Publicado en: Scientific Reports, Edición vol 11, issue 1, 2021, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-021-99654-6

Cryo-EM studies of membrane proteins at 200 keV

Autores: Chancievan Thangaratnarajah, Jan Rheinberger, Cristina Paulino
Publicado en: Current Opinion in Structural Biology, Edición 76, 2024, Página(s) 102440, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2022.102440

Artificial cells with viscoadaptive behavior based on hydrogel-loaded giant unilamellar vesicles

Autores: Antoni Llopis-Lorente, Maaike J. G. Schotman, Heorhii V. Humeniuk, Jan C. M. van Hest, Patricia Y. W. Dankers and Loai K. E. A. Abdelmohsen
Publicado en: Chemical Science, Edición Edición 2, 2024, 2024, Página(s) 629-638, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d3sc04687g

Identification and characterization of archaeal and bacterial F420-dependent thioredoxin reductases

Autores: Guang Yang, Hein J Wijma, Henriëtte J Rozeboom, Maria Laura Mascotti, Marco W Fraaije
Publicado en: The FEBS Journal, Edición volume 290, issue 19, 2023, Página(s) 4777-4791, ISSN 1742-464X
Editor: Blackwell Publishing Inc.
DOI: 10.1111/febs.16896

Enantioselective Self-Replicators

Autores: Shuo Yang; Yannick Geiger; Marc Geerts; Marcel J. Eleveld; Armin Kiani; Sijbren Otto
Publicado en: Journal of the American Chemical Society, Edición volume 145, issue 30, 2023, Página(s) 16889-16898, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.3c05472

Long-term tidal evolution of the TRAPPIST-1 system

Autores: R. Brasser, G. Pichierri, V. Dobos, A. C. Barr
Publicado en: Monthly Notices of the Royal Astronomical Society, Edición 13652966, 2022, Página(s) 2373–2385, ISSN 1365-2966
Editor: Oxford University Press
DOI: 10.1093/mnras/stac1907

All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement

Autores: Gregory B. Boursalian, Eise R. Nijboer, Ruth Dorel, Lukas Pfeifer, Omer Markovitch, Alex Blokhuis, Ben L. Feringa
Publicado en: Journal of the American Chemical Society, Edición 142, 2023, Página(s) 16868-16876, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c08249

All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement

Autores: Boursalian, Gregory B.; Nijboer, Eise R.; Dorel, Ruth; Pfeifer, Lukas; Markovitch, Omer; Blokhuis, Alex; Feringa, Ben L.
Publicado en: American Chemical Society, Edición 142, 39, 2020, Página(s) 16868–16876, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c08249

A conserved sequence motif in the E. coli soluble FAD-containing pyridine nucleotide transhydrogenase is important for reaction efficiency

Autores: Michele Partipilo; Guang Yang; Maria Laura Mascotti; Hein J. Wijma; Dirk Jan Slotboom; Marco W. Fraaije
Publicado en: The Journal of Biological Chemistry, Edición 298, issue 9, 2022, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2022.102304

Role of Curvature‐Sensing Proteins in the Uptake of Nanoparticles with Different Mechanical Properties

Autores: Daphne Montizaan, Catherine Saunders, Keni Yang, Sajitha Sasidharan, Sourav Maity, Catharina Reker‐Smit, Marc C. A. Stuart, Costanza Montis, Debora Berti, Wouter H. Roos, Anna Salvati
Publicado en: Small, Edición 19, 2023, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202303267

From the mysteries of the fly agaric: The toxin of the Amanita muscaria (Das Gift des Fliegenpilzes: Von den Geheimnissen des Narrenschwamms)

Autores: Sebastian Obermaier*, Michael Müller
Publicado en: Chemie in unserer zeit, Edición vol 56, 2022, Página(s) """256--264", ISSN 0009-2851
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/ciuz.202000085

Quorum sensing communication between lipid-based artificial cells

Autores: Antoni Llopis-Lorente, Bastiaan C. Buddingh', R. Martínez-Máñez, Jan C. M. van Hest, Loai K. E. Abdelmohsen
Publicado en: Chemical Communications, Edición 59, 2024, Página(s) 579-582, ISSN 1359-7345
Editor: Royal Society of Chemistry
DOI: 10.1039/d2cc05367e

Small-molecule autocatalysis drives compartment growth, competition and reproduction

Autores: Heng Lu, Alex Blokhuis, Rebecca Turk-MacLeod, Jayaprakash Karuppusamy, Andrea Franconi, Gabrielle Woronoff, Cyrille Jeancolas, Afshin Abrishamkar, Estelle Loire, Fabien Ferrage, Philippe Pelupessy, Ludovic Jullien, Eörs Szathmary, Philippe Nghe & Andrew D. Griffiths
Publicado en: Nature Chemistry, Edición nr 16, 2024, Página(s) 70-78, ISSN 1755-4349
Editor: Springer Nature
DOI: 10.1038/s41557-023-01276-0

Water content of rocky exoplanets in the habitable zone

Autores: Ádám Boldog, Vera Dobos, László L. Kiss, Marijn van der Perk, Amy C. Barr
Publicado en: Astronomy & Astrophysics, Edición 681, 2024, Página(s) A109, ISSN 0004-6361
Editor: Springer Verlag
DOI: 10.1051/0004-6361/202346988

A comparative laboratory study of soft X-ray-induced ionization and fragmentation of five small PAH cations

Autores: Yining Huo, Mónica K. Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J. Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: The European Physical Journal D, Edición 77, 2023, ISSN 1434-6060
Editor: Springer Verlag
DOI: 10.1140/epjd/s10053-023-00763-w

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Autores: Sotiria Tavoulari, Tom J.J. Schirris, Vasiliki Mavridou, Chancievan Thangaratnarajah, Martin S. King, Daniel T.D. Jones, Shujing Ding, Ian M. Fearnley, Edmund R.S. Kunji
Publicado en: Molecular Metabolism, Edición 60, 2022, Página(s) 101469, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101469

RNA-Protein Interactions in Molecular Life and Health: A Computational Approach

Autores: Driver, Mark D.; Onck, Patrick R.
Publicado en: Biophysical Journal, 120(3), 81A - 81A. CELL PRESS, Edición 120, 2021, Página(s) 81A--81A, ISSN 0006-3495
Editor: Biophysical Society
DOI: 10.1016/j.bpj.2020.11.702

Evolution of enzyme functionality in the flavin-containing monooxygenases

Autores: Gautier Bailleul, Guang Yang, Callum R Nicoll, Andrea Mattevi, Marco W Fraaije, Maria Laura Mascotti
Publicado en: Nature Communications, Edición '14:1042, 2023, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-36756-x

Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity

Autores: Dávid Komáromy*, Theodora Tiemersma-Wegman, Johan Kemmink, Giuseppe Portale, Paul R. Adamski, Alex Blokhuis, Friso S. Aalbers, Ivana Marić, Guillermo Monreal Santiago, Jim Ottelé, Ankush Sood, Vittorio Saggiomo, Bin Liu, Pieter van der Meulen, Sijbren Otto
Publicado en: Chem, Edición volume 7, 2021, Página(s) 1933--1951, ISSN 2451-9308
Editor: Elsevier
DOI: 10.1016/j.chempr.2021.05.020

Selective Disruption of Survivin's Protein-Protein Interactions: A Supramolecular Approach Based on Guanidiniocarbonylpyrrole

Autores: Dennis Aschmann, Dr. Cecilia Vallet, Dr. Sunil K. Tripathi, Dr. Yasser B. Ruiz-Blanco, Max Brabender, Prof. Dr. Carsten Schmuck, Prof. Dr. Elsa Sanchez-Garcia, Prof. Dr. Shirley K. Knauer, Prof.Dr. Michael Giese
Publicado en: ChemBioChem, Edición issue 5, 2022, ISSN 1439-4227
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202100618

Lipid-Based Nanoparticle Functionalization with Coiled-Coil Peptides for <i>In Vitro</i> and <i>In Vivo</i> Drug Delivery

Autores: Dennis Aschmann; Renzo A. Knol; Alexander Kros
Publicado en: Accounts of Chemical Research, Edición 57, 8,, 2024, Página(s) 1098–1110, ISSN 0001-4842
Editor: American Chemical Society
DOI: 10.1021/acs.accounts.3c00769

Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension

Autores: Apirat Chaikuad, Chancievan Thangaratnarajah, Frank von Delft, Alex N. Bullock
Publicado en: Scientific Reports, Edición 9, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-54830-7

Cryo-EM studies of membrane proteins at 200 keV

Autores: Chancievan Thangaratnarajah, Jan Rheinberger, Cristina Paulino
Publicado en: Current Opinion in Structural Biology, Edición volume 76, 2022, ISSN 1879-033X
Editor: Elsevier
DOI: 10.1016/j.sbi.2022.102440

Ancestral-sequence reconstruction unveils the structural basis of function in mammalian FMOs

Autores: Callum R Nicoll, Gautier Bailleul, Filippo Fiorentini, María Laura Mascotti, Marco W Fraaije*, Andrea Mattevi
Publicado en: Nature Structural & Molecular Biology, Edición vol 27, 2019, Página(s) 14-24, ISSN 1545-9985
Editor: Nature Publishing Group
DOI: 10.1038/s41594-019-0347-2

Fitness landscape of substrate-adaptive mutations in evolved amino acid-polyamine-organocation transporters

Autores: Foteini Karapanagioti, Úlfur Águst Atlason, Dirk J Slotboom, Bert Poolman, Sebastian Obermaier
Publicado en: eLife, Edición 13, 2024, ISSN 2050-084X
Editor: eLife Sciences Publications
DOI: 10.7554/elife.93971.3

Structural properties of the HNF-1A transactivation domain

Autores: Laura Kind; Mark Driver; Arne Raasakka; Patrick R. Onck; Pål Rasmus Njølstad; Thomas Arnesen; Petri Kursula
Publicado en: JournalFrontiers in Molecular Biosciences, Edición volume 10, 2023, ISSN 2296-889X
Editor: Frontiers Media S.A.
DOI: 10.1101/2023.06.23.546236

Motility of Active Microparticles in Cell-Sized Lipid Vesicles

Autores: Shidong Song; Antoni Llopis-Lorente; Alexander F. Mason; Loai K. E. A. Abdelmohsen; Jan C. M. van Hest
Publicado en: Journal of the American Chemical Society, Edición volume 144, issue 30, 2022, Página(s) 13831–13838, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.2c05232

Multi-site-specific polymer grafting from nucleic acids

Autores: Sandeepa K. Vittala 1, Roxanne E. Kieltyka
Publicado en: Chem, Edición Vol 9 , issue 11, 2023, Página(s) Pages 3018-3020, ISSN 2451-9308
Editor: Elsevier
DOI: 10.1016/j.chempr.2023.10.012

Impact of ancestral sequence reconstruction on mechanistic and structural enzymology

Autores: Callum R Nicoll, Marta Massari, Marco W Fraaije, Maria Laura Mascotti, Andrea Mattevi
Publicado en: Current Opinion in Structural Biology, Edición volume 82, 2023, Página(s) article number 102669, ISSN 0959-440X
Editor: Elsevier BV
DOI: 10.1016/j.sbi.2023.102669

Universal motifs and the diversity of autocatalytic systems

Autores: Alex Blokhuis*, David Lacoste, Philippe Nghe
Publicado en: Proceedings of the National Academy of Sciences of the United States of America, Edición volume 117, nr 41, 2020, Página(s) 25230-25236, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2013527117

Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties

Autores: Gautier Bailleul, Callum R. Nicoll, María Laura Mascotti, Andrea Mattevi, Marco W. Fraaije
Publicado en: Journal of Biological Chemistry, Edición 296, 2021, Página(s) 100221, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1074/jbc.ra120.016297

Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

Autores: Gema Vivo-Llorca; Ángela Morellá-Aucejo; Alba García-Fernández; Paula Díez; Antoni Llopis-Lorente; Mar Orzáez; Ramón Martínez-Máñez
Publicado en: International Journal of Nanomedicine, Edición 17, 2022, Página(s) Pages 409 - 422, ISSN 1176-9114
Editor: Dove Medical Press Ltd
DOI: 10.2147/ijn.s323802

Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity

Autores: Dávid Komáromy, Theodora Tiemersma-Wegman, Johan Kemmink, Giuseppe Portale, Paul R. Adamski, Alex Blokhuis, Friso S. Aalbers, Ivana Marić, Guillermo Monreal Santiago, Jim Ottelé, Ankush Sood, Vittorio Saggiomo, Bin Liu, Pieter van der Meulen, Sijbren Otto
Publicado en: Chem, Edición 7, 2023, Página(s) 1933-1951, ISSN 2451-9294
Editor: Elsevier
DOI: 10.1016/j.chempr.2021.05.020

Reconstructing the evolutionary history of F-420-dependent dehydrogenases

Autores: M Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W. Fraaije
Publicado en: Scientific Reports, Edición vol 8, issue 1, 2018, Página(s) 8, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-35590-2

Impacts of Severe Tropical Cyclone Olwyn and the biogeomorphic response, Hamelin Pool, Shark Bay, Western Australia

Autores: Thérèse E. Morris, Stephen Morris, Peter R.C.S. Fearns, Aditya Chopra, Mehrooz F. Aspandair, Lindsay B. Collins, Micheal J. O'Leary, Pieter T. Visscher
Publicado en: The Depositional Record, Edición 20554877, 2022, Página(s) 786-828, ISSN 2055-4877
Editor: Wiley
DOI: 10.1002/dep2.183

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast

Autores: Maria Szomek; Peter Reinholdt; Hanna-Loisa Walther; Holger A. Scheidt; Peter Müller; Sebastian Obermaier; Bert Poolman; Jacob Kongsted; Daniel Wüstner
Publicado en: Biochimica et Biophysica Acta - Biomembranes, 1864(11):184012, Edición 3, 2022, ISSN 0005-2736
Editor: Elsevier BV
DOI: 10.1016/j.bbamem.2022.184012

Key features of inhibitor binding to the human mitochondrial pyruvate carrier hetero-dimer

Autores: Sotiria Tavoulari*, Tom J J Schirris, Vasiliki Mavridou, Chancievan Thangaratnarajah, Martin S King, Daniel T D Jones, Shujing Ding, Ian M Fearnley, Edmund R S Kunji
Publicado en: Molecular metabolism, Edición vol 60, 2022, Página(s) 101469, 13 pages, ISSN 2212-8778
Editor: Elsevier GmbH
DOI: 10.1016/j.molmet.2022.101469

Complexes with Atomic Gold Ions: Efficient Bis-Ligand Formation

Autores: Felix Duensing, Elisabeth Gruber, Paul Martini, Marcelo Goulart, Michael Gatchell, Bilal Rasul, Olof Echt, Fabio Zappa, Masoomeh Mahmoodi-Darian*, Paul Scheier
Publicado en: Molecules, Edición volume 26, 2021, ISSN 1431-5157
Editor: MDPI AG
DOI: 10.3390/molecules26123484

CRISPR-based transcriptional activation tool for silent genes in filamentous fungi

Autores: László Mózsik, Mirthe Hoekzema, Niels A W de Kok, Roel A L Bovenberg, Yvonne Nygård, Arnold J M Driessen
Publicado en: Scientific Reports, Edición vol 11, issue 1, 2021, Página(s) 13 pages, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-80864-3

Switching the Mode of Drug Release from a Reaction-Coupled Low-Molecular-Weight Gelator System by Altering Its Reaction Pathway

Autores: Willem E. M. Noteborn; Sandeepa K. Vittala; Maria Broto Torredemer; Chandan Maity; Frank Versluis; Rienk Eelkema; Roxanne E. Kieltyka
Publicado en: Biomacromolecules, 24(1), 377 - 386. AMER CHEMICAL SOC, Edición 24, 2023, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.2c01197

The SLC25 Carrier Family: Important Transport Proteins in Mitochondrial Physiology and Pathology

Autores: Edmund R. S. Kunji, Martin S. King, Jonathan J. Ruprecht, Chancievan Thangaratnarajah
Publicado en: Physiology, Edición 35/5, 2020, Página(s) 302-327, ISSN 1548-9213
Editor: American Physiological Society
DOI: 10.1152/physiol.00009.2020

Insights into the bilayer-mediated toppling mechanism of a folate-specific ECF transporter by cryo-EM

Autores: Chancievan Thangaratnarajah, Jan Rheinberger, Cristina Paulino, Dirk J. Slotboom
Publicado en: Proceedings of the National Academy of Sciences, Edición 118/34, 2021, Página(s) e2105014118, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2105014118

Natamycin sequesters ergosterol and interferes with substrate transport by the lysine transporter Lyp1 from yeast

Autores: Maria Szomek, Peter Reinholdt, Hanna-Loisa Walther, Holger A. Scheidt, Peter Müller, Sebastian Obermaier, Bert Poolman, Jacob Kongsted, Daniel Wüstner
Publicado en: Biochimica et Biophysica Acta (BBA) - Biomembranes, Edición 1864, 2024, Página(s) 184012, ISSN 0005-2736
Editor: Elsevier BV
DOI: 10.1016/j.bbamem.2022.184012

"Soft-x-ray spectroscopy of <mml:math xmlns:mml=""http://www.w3.org/1998/Math/MathML""><mml:msup><mml:mi mathvariant=""normal"">coronene</mml:mi><mml:mo>+</mml:mo></mml:msup></mml:math> and <mml:math xmlns:mml=""http://www.w3.org/1998/Math/MathML""><mml:msup><mml:mrow><mml:mo>(</mml:mo><mml:mtext>coronene</mml:mtext><mml:mo>+</mml:mo><mml:mi mathvariant=""normal"">H</mml:mi><mml:mo>)</mml:mo></mml:mrow><mm"

Autores: Yining Huo; Mónica K. Espinoza Cangahuala; Marcelo Goulart; Vicente Zamudio-Bayer; Markus Kubin; Martin Timm; J. Tobias Lau; Bernd von Issendorff; Ronnie Hoekstra; Shirin Faraji; Thomas Schlathölter
Publicado en: Physical Review A - Atomic, Molecular, and Optical Physics, Edición volume 106, issue 6, 2022, Página(s) 11, ISSN 2469-9926
Editor: American Physical Society
DOI: 10.1103/physreva.106.063104

Bidirectional ATP-driven transport of cobalamin by the mycobacterial ABC transporter BacA

Autores: Mark Nijland; Solène N. Lefebvre; Chancievan Thangaratnarajah; Dirk J. Slotboom
Publicado en: Nature Communications, Edición 15 / 1, 2024, Página(s) 9 pages, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-46917-1

Survival of Exomoons Around Exoplanets

Autores: V. Dobos, S. Charnoz, A. Pál, A. Roque-Bernard, Gy. M. Szabó
Publicado en: Publications of the Astronomical Society of the Pacific, Edición 133/1027, 2021, Página(s) 094401, ISSN 0004-6280
Editor: University of Chicago Press
DOI: 10.1088/1538-3873/abfe04

Evolutionary and structural analyses of the NADPH oxidase family in eukaryotes reveal an initial calcium dependency

Autores: Marta Massari; Callum R. Nicoll; Sara Marchese; Andrea Mattevi; Maria Laura Mascotti
Publicado en: Redox Biology, Edición volume 56, October, 2022, ISSN 2213-2317
Editor: Elsevier BV
DOI: 10.1016/j.redox.2022.102436

Turning Enantiomeric Relationships into Diastereomeric Ones: Self-Resolving α-Ureidophosphonates and Their Organocatalytic Enantioselective Synthesis

Autores: Vanda Dašková; Damián Padín; Ben L. Feringa
Publicado en: Journal of the American Chemical Society, Edición 8, weekly, 2022, ISSN 1520-5126
Editor: American Chemical Society
DOI: 10.1021/jacs.2c10911

Expulsion mechanism of the substrate-translocating subunit in ECF transporters

Autores: Chancievan Thangaratnarajah, Mark Nijland, Luís Borges-Araújo, Aike Jeucken, Jan Rheinberger, Siewert J. Marrink, Paulo C. T. Souza, Cristina Paulino & Dirk J. Slotboom
Publicado en: Nature Communications, Edición issue 1, article 4484, 2023, Página(s) 14 pages, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-023-40266-1

Reconstructing the evolutionary history of F420-dependent dehydrogenases

Autores: M. Laura Mascotti, Hemant Kumar, Quoc-Thai Nguyen, Maximiliano Juri Ayub, Marco W. Fraaije
Publicado en: Scientific Reports, Edición 8, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-018-35590-2

Investigating the biochemical signatures and physiological roles of the FMO family using molecular phylogeny

Autores: C. R. Nicoll, M. L. Mascotti
Publicado en: BBA Advances, Edición volume 4, 2023, Página(s) article 100108, ISSN 2667-1603
Editor: Elsevier
DOI: 10.1016/j.bbadva.2023.100108

Investigating the biochemical signatures and physiological roles of the FMO family using molecular phylogeny

Autores: C.R. Nicoll, M.L. Mascotti
Publicado en: BBA Advances, Edición 4, 2023, Página(s) 100108, ISSN 2667-1603
Editor: Elsevier
DOI: 10.1016/j.bbadva.2023.100108

Pathogenic variants of the mitochondrial aspartate/glutamate carrier causing citrin deficiency

Autores: Sotiria Tavoulari, Denis Lacabanne, Chancievan Thangaratnarajah, Edmund R S Kunji*
Publicado en: Trends in endocrinology and metabolism, Edición vol 33, issue 8, 2022, Página(s) 539-553, ISSN 1043-2760
Editor: Elsevier BV
DOI: 10.1016/j.tem.2022.05.002

One Soai reaction, two mechanisms?

Autores: Yannick Geiger
Publicado en: Chemical Society Reviews, Edición 14604744, 2022, ISSN 1460-4744
Editor: Royal Society of Chemistry
DOI: 10.1039/d1cs01038g

Endocytosis-like DNA uptake by cell wall-deficient bacteria

Autores: Renée Kapteijn, Shraddha Shitut, Dennis Aschmann, Le Zhang, Marit de Beer, Deniz Daviran, Rona Roverts, Anat Akiva, Gilles P. van Wezel, Alexander Kros, Dennis Claessen
Publicado en: Nature Communications, Edición 13, 2022, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-022-33054-w

Light-driven eco-evolutionary dynamics in a synthetic replicator system

Autores: Kai Liu, Alex Blokhuis, Chris van Ewijk, Armin Kiani, Juntian Wu, Wouter H Roos, Sijbren Otto
Publicado en: Nature Chemistry, Edición 16, 2024, Página(s) 79–88, ISSN 1755-4330
Editor: Nature Publishing Group
DOI: 10.1038/s41557-023-01301-2

A mycobacterial ABC transporter mediates the uptake of hydrophilic compounds

Autores: Stephan Rempel, Cornelius Gati, Mark Nijland, Chancie Thangaratnarajah, Alexandros Karyolaimos, Jan-Willem L. de Gier, Albert Guskov, Dirk Slotboom*
Publicado en: Nature, Edición vol 580 issue 7803, 2020, Página(s) 409-412, ISSN 0028-0836
Editor: Nature Publishing Group
DOI: 10.1038/s41586-020-2072-8

An X-ray spectroscopy study of structural stability of superhydrogenated pyrene derivatives

Autores: Yining Huo, Mónica Espinoza Cangahuala, Vicente Zamudio-Bayer, Marcelo Goulart, Markus Kubin, Martin Timm, J Tobias Lau, Bernd von Issendorff, Ronnie Hoekstra, Shirin Faraji, Thomas Schlathölter
Publicado en: Monthly Notices of the Royal Astronomical Society, Edición 523 /1, 2023, Página(s) 865-875, ISSN 1365-2966
Editor: Oxford University Press
DOI: 10.1093/mnras/stad1341

The topological shadow of $${{{\mathbb {F}}}_1}$$-geometry: congruence spaces

Autores: Oliver Lorscheid, Samarpita Ray
Publicado en: Mathematische Zeitschrift, Edición 306, 2024, ISSN 0025-5874
Editor: Springer Verlag
DOI: 10.1007/s00209-023-03425-0

Chemical Cascading Between Polymersomal Nanoreactor Populations

Autores: Yigit Altay, Antoni Llopis-Lorente, Loai K. E. A. Abdelmohsen, Jan C.M. van Hest
Publicado en: Macromolecular Chemistry and Physics, Edición Volume 224, Edición 1, 2023, ISSN 1022-1352
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/macp.202200269

Exploring Intra- and Inter-Regional Interactions in the IDP α-Synuclein Using smFRET and MD Simulations

Autores: Gobert Heesink; Mirjam J. Marseille; Mohammad A. A. Fakhree; Mark D. Driver; Kirsten A. van Leijenhorst-Groener; Patrick R. Onck; Christian Blum; Mireille M.A.E. Claessens
Publicado en: Biomacromolecules, Edición volume 24, issue 8, 2023, Página(s) 3680–3688, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00404

Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives

Autores: Daniel Eggerichs; Nils Weindorf; Maria Laura Mascotti; Natalie Welzel; Marco W. Fraaije; Dirk Tischler
Publicado en: The Journal of Biological Chemistry, Edición volume 13, issue 7, 2023, ISSN 0021-9258
Editor: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.104898

In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy

Autores: Oscar Escalona-Rayo , Ye Zeng , Renzo A. Knol , Thomas J.F. Kock , Dennis Aschmann , Bram Slütter , Alexander Kros
Publicado en: Biomedicine & Pharmacotherapy, Edición vol 165, 2023
Editor: Elsevier Masson SAS
DOI: 10.1016/j.biopha.2023.115065

Water content of rocky exoplanets in the habitable zone

Autores: Ádám Boldog, Vera Dobos, László L. Kiss, Marijn van der Perk and Amy C. Barr
Publicado en: Astronomy & Astrophysics, Edición Volume 681,, 2024, Página(s) 13 pages
Editor: EDP Sciences
DOI: 10.1051/0004-6361/202346988

Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis

Autores: Imke AB Pijpers, Shoupeng Cao, Antoni Llopis-Lorente, Jianzhi Zhu, Shidong Song, Rick RM Joosten, Fenghua Meng, Heiner Friedrich, David S Williams, Samuel Sánchez, Jan CM van Hest, Loai KEA Abdelmohsen
Publicado en: Nano Letters, Edición issue 20 / 6, 2020, Página(s) 4472-4480
Editor: American Chemical Society
DOI: 10.1021/acs.nanolett.0c01268

PyATMOS: A Scalable Grid of Hypothetical Planetary Atmospheres

Autores: Chopra, Aditya ; Bell, Aaron C ; Fawcett, William ; Talebi, Rodd ; Angerhausen, Daniel ; Güneş Baydin, Atılım ; Berea, Anamaria ; Cabrol, Nathalie A. ; Kempes, Christopher ; Mascaro, Massimo
Publicado en: astro-ph > arXiv:2308.10624, 2023, Página(s) 9 pages
Editor: Astrophysics Data System
DOI: 10.48550/arxiv.2308.10624

EXO-ATMOS: A scalable grid of hypothetical planetary atmospheres

Autores: Chopra, Aditya ; Bell, Aaron ; Fawcett, William ; Talebi, Rodd ; Angerhausen, Daniel ; Güneş Baydin, Atılım ; Berea, Anamaria ; Cabrol, Nathalie A. ; Kempes, Christopher P. ; Mascaro, Massimo
Publicado en: 14th Europlanet Science Congress 2020, held virtually, 21 September 2020 - 9 October, 2020., 2020
Editor: Astrophysics Data System
DOI: 10.5194/epsc2020-664

The Biological Overview Effect

Autores: Lineweaver, Charles H. ; Chopra, Aditya
Publicado en: Astrophysics and Space Science Proceedings, Edición volume 58, 2021, ISBN 978-3-030-70482-7
Editor: springer
DOI: 10.1007/978-3-030-70482-7_11

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