Periodic Reporting for period 1 - ARDRE (Ageing, Regeneration, and Drug Research)
Periodo di rendicontazione: 2019-08-01 al 2021-07-31
As life expectancy and the proportion of elderly people increase, our societies need to rise to the challenges accompanying this demographic shift. In the European Union, the segment of those aged 80 years or over is projected to more than double between 2017 and 2080, from 5.5 % to 12.7 % (WHO, Eurostat). Similar trends are observed for industrialized countries globally. For the ageing individual, healthy ageing is a foremost goal. As yet, our health systems, public and private institutions caring for the elderly are not sufficiently prepared, and the costs for treating age-related diseases are predicted to be huge. Therefore, effective measures to promote healthy ageing are urgently needed. The scientific aims of ARDRE are to explore molecular mechanisms leading to severe disabilities associated with old age, and identify small molecules with the potential to prevent their development. Innovative new insights are expected through the exploration of evolutionarily conserved molecular mechanisms of ageing and regeneration across kingdoms, comprising life forms as distant as plants and fungi, nematodes and tunicates to fish and mice, and finally humans. The ultimate goal is to develop regenerative strategies for (at least partly) reversing age-related damage to various tissues and organ systems.
ARDRE is an inter- and multidisciplinary consortium comprising scientists from the Faculty of Biology and the Faculty of Chemistry and Pharmacy of the University of Innsbruck, Austria. They committed to establish a doctoral programme (DP) for 12 early stage researchers (ESR) with the aim to transfer their knowledge of ageing and regeneration mechanisms, and drug research to the next generation of scientists, and train the ESR at the highest level possible.
ARDRE has successfully implemented a number of activities to promote early-stage researchers in the first few months: The recruitment of all PhD positions was successfully completed in a fully transparent way. The rigorous recruitment procedure ensured that only excellent candidates were chosen.12 early stage researchers have been recruited and started their research programme.
We were able to launch a number of supervision arrangements to provide our PhD students with the best possible support and benefit from the interdisciplinary nature of the program. Training on research skills within the appropriate disciplines has started up, as well as additional training in non-research-oriented transferable skills. Each of our ARDRE PhD students has officially submitted their diploma thesis. From the beginning they have been encouraged to gain new expertise outside their own discipline with regular Journal Club Meetings (total 17 ) and with networking activities with other PhD programmes from both Innsbruck Universities. Various conferences were organized in cooperation. For the coming year, concrete plans include the organization of the Joint AGE_REG & ARDRE Winter School & Ethics Meeting, the 2nd FEBS Workshop Ageing and Regeneration, and the next Life Science PhD Meeting in Innsbruck. To bring together our ARDRE ESR in an informal setting we have created ARDRE MINI RETREATS. In absence of their supervisors, the ARDRE ESR have met three times already to exchange ideas.
The media activities were carried out on UIBK Newsroom about the ARDRE DP. The ARDRE website hosted at the server of the Innsbruck University (UIBK) was first established as recruiting page with short descriptions of the programme, research and extra training, research areas, the thesis projects, the ARDRE supervisors as well as the application information. In M 13-16 we have turned the ARDRE recruiting page into a key communication resource highlighting the details of the ARDRE. Our first short image video gives a brief overview on our research areas. Our PhD students have been encouraged to write short posts for our new ARDRE Instagram account. With regard to cofinancing, we would like to point out, that our ESR Camille Brucker has recently successfully applied for co-funding: Her project will be funded with the amount of EUR 5.000 sponsored by our Vice Rector for Research.