Skip to main content

Drug combinations for rewriting trajectories of renal pathologies in type II diabetes (DC-ren)

Project description

Dynamical systems theory could support physicians to select optimal therapies

Diseases, co-morbidities, and patients responses to certain therapies are the result of a complicated interplay of numerous factors. The relationships defining how this intricate network of inputs leads to various outputs is extremely difficult to derive using conventional means. Thanks to Big Data, high-level applied mathematics and computers, the EU-funded DC-ren project is developing a tool that will take all this and more into account, and enable optimised personalised drug therapies for significantly enhanced outcomes. The team is focusing on diabetic kidney disease, a common co-morbidity of type 2 diabetes often accompanied by cardiovascular disease. Currently, the drug cocktails targeting it produce highly varied responses. Thanks to its vast patient database, advanced experimental techniques and dynamical systems theory, DC-ren is developing a completely new and widely applicable computational framework for decision support.

Field of science

  • /medical and health sciences/basic medicine/pathology
  • /medical and health sciences/clinical medicine/endocrinology/diabetes/diabetic nephropathy
  • /medical and health sciences/clinical medicine/nephrology/kidney diseases
  • /natural sciences/mathematics/applied mathematics/dynamical systems

Call for proposal

H2020-SC1-2019-Two-Stage-RTD
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

MEDIZINISCHE UNIVERSITAT INNSBRUCK
Address
Christoph Probst Platz 1
6020 Innsbruck
Austria
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 045 300

Participants (7)

EMERGENTEC BIODEVELOPMENT GMBH
Austria
EU contribution
€ 898 775
Address
Gersthofer Strasse 29-31
1180 Vienna
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MEDIZINISCHE UNIVERSITAET WIEN
Austria
EU contribution
€ 948 800
Address
Spitalgasse 23
1090 Wien
Activity type
Higher or Secondary Education Establishments
MOSAIQUES DIAGNOSTICS GMBH
Germany
EU contribution
€ 701 050
Address
Rotenburger Strasse 20
30659 Hannover
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
EU contribution
€ 554 925
Address
Hanzeplein 1
9713 GZ Groningen
Activity type
Higher or Secondary Education Establishments
UNIVERSITA CA' FOSCARI VENEZIA
Italy
EU contribution
€ 781 405
Address
Dorsoduro 3246
30123 Venezia
Activity type
Higher or Secondary Education Establishments
WEIZMANN INSTITUTE OF SCIENCE
Israel
EU contribution
€ 515 237,50
Address
Herzl Street 234
7610001 Rehovot
Activity type
Higher or Secondary Education Establishments
REGION HOVEDSTADEN
Denmark
EU contribution
€ 522 987,50
Address
Kongens Vaenge 2
3400 Hillerod
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)