Design Principles of Branching Morphogenesis

Project Information

Demos

Grant agreement ID: 851288

DOI 10.3030/851288

EC signature date 19 November 2019

Start date 1 July 2020

End date 30 June 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 452 604,00

EU contribution € 1 452 604,00

Coordinated by

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (17)

Morphogen gradient orchestrates pattern-preserving tissue morphogenesis via motility-driven unjamming

Author(s): Diana Pinheiro; Roland Kardos; Edouard Hannezo; Carl-Philipp Heisenberg
Published in: Nature Physics, 2022, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-022-01787-6

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

Author(s): Simona Hankeova; Jakub Salplachta; Tomas Zikmund; Michaela Kavkova; Noémi Van Hul; Adam Brinek; Veronika Smekalova; Jakub Laznovsky; Feven Dawit; Josef Jaros; Vítězslav Bryja; Urban Lendahl; Ewa Ellis; Antal Nemeth; Björn Fischler; Edouard Hannezo; Jozef Kaiser; Emma Rachel Andersson
Published in: eLife, 2020, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.60916

Retrograde movements determine effective stem cell numbers in the intestine

Author(s): Maria Azkanaz, Bernat Corominas-Murtra, Saskia I. J. Ellenbroek, Lotte Bruens, Anna T. Webb, Dimitrios Laskaris, Koen C. Oost, Simona J. A. Lafirenze, Karl Annusver, Hendrik A. Messal, Sharif Iqbal, Dustin J. Flanagan, David J. Huels, Felipe Rojas-Rodríguez, Miguel Vizoso, Maria Kasper, Owen J. Sansom, Hugo J. Snippert, Prisca Liberali, Benjamin D. Simons, Pekka Katajisto, Edouard Hannezo, Jacco
Published in: Nature, 2022, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-04962-0

A self-generated Toddler gradient guides mesodermal cell migration

Author(s): Jessica Stock; Tomas Kazmar; Friederike Schlumm; Edouard Hannezo; Andrea Pauli
Published in: Science Advances, 2022, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.add2488

Theory of branching morphogenesis by local interactions and global guidance

Author(s): Ucar, Mehmet C, Kamenev Dmitrii, Sunadome Kazunori, Fachet, Dominik, Lallemend Francois, Adameyko Igor, Hadjab, Saida, Hannezo, Edouard
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27135-5

Modelling the dynamics of mammalian gut homeostasis

Author(s): Bernat Corominas-Murtra, Edouard Hannezo
Published in: Seminars in Cell & Developmental Biology, 2022, ISSN 1084-9521
Publisher: Academic Press
DOI: 10.1016/j.semcdb.2022.11.005

Lineage tracing identifies heterogeneous hepatoblast contribution to cell lineages and postembryonic organ growth dynamics

Author(s): Iris. A. Unterweger, Julie Klepstad, Edouard Hannezo, Pia R. Lundegaard, Ala Trusina, Elke A. Ober
Published in: PLOS Biology, Issue 21, 2024, Page(s) e3002315, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.3002315

Cell surface fluctuations regulate early embryonic lineage sorting

Author(s): Ayaka Yanagida; Elena Corujo-Simon; Christopher K. Revell; Preeti Sahu; Giuliano G. Stirparo; Irene M. Aspalter; Alex K. Winkel; Ruby Peters; Henry De Belly; Davide A.D. Cassani; Sarra Achouri; Raphael Blumenfeld; Kristian Franze; Edouard Hannezo; Ewa K. Paluch; Jennifer Nichols; Kevin J. Chalut;
Published in: Cell, 2022, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2022.01.022

Cell fate coordinates mechano-osmotic forces in intestinal crypt formation

Author(s): Yang, Qiutan; Xue, Shilei, Chan, Chii Jou, Rempfler Markus, Vischi Dario, Maurer-Gutierrez Francisca, Hiiragi, Takashi, Hannezo, Edouard, Liberali Prisca
Published in: Nature Cell Biology, 2021, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-021-00700-2

Theory of mechanochemical patterning and optimal migration in cell monolayers

Author(s): Boocock, Daniel R, Hino Naoya, Ruzickova, Natalia, Hirashima, Tsuyoshi, Hannezo, Edouard
Published in: Nature Physics, 2021, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-020-01037-7

Self-organized and directed branching results in optimal coverage in developing dermal lymphatic networks

Author(s): Mehmet Can Uçar, Edouard Hannezo, Emmi Tiilikainen, Inam Liaqat, Emma Jakobsson, Harri Nurmi, Kari Vaahtomeri
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-41456-7

Interplay between Mechanochemical Patterning and Glassy Dynamics in Cellular Monolayers

Author(s): Daniel Boocock, Tsuyoshi Hirashima, Edouard Hannezo
Published in: PRX Life, Issue 1, 2023, ISSN 2835-8279
Publisher: American Physical Society.
DOI: 10.1103/prxlife.1.013001

Geometry-driven migration efficiency of autonomous epithelial cell clusters

Author(s): Eléonore Vercruysse, David B. Brückner, Manuel Gómez-González, Alexandre Remson, Marine Luciano, Yohalie Kalukula, Leone Rossetti, Xavier Trepat, Edouard Hannezo, Sylvain Gabriele
Published in: Nature Physics, Issue 20, 2024, Page(s) 1492-1500, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1038/s41567-024-02532-x

Rigidity percolation uncovers a structural basis for embryonic tissue phase transitions

Author(s): Nicoletta Petridou, Bernat Corominas-Murtra, Carl-Philipp Heisenberg, Edouard Hannezo
Published in: Cell, 2021, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.02.017

Large-scale curvature sensing by epithelial monolayers depends on active cell mechanics and nuclear mechanoadaptation

Author(s): Lorena Redondo Morata; Marine Luciano; Shi-Lei Xue; Winnok H. De Vos; Lorena Morata; Mathieu Surin; Frank Lafont; Edouard Hannezo; Sylvain Gabriele
Published in: Nature Physics, 2021, ISSN 1745-2473
Publisher: Nature Publishing Group
DOI: 10.1101/2020.07.04.187468

Stem cell lineage survival as a noisy competition for niche access

Author(s): Corominas-Murtra Bernat, Scheele Colinda, Kishi Kasumi Ellenbroek Saskia, Simons Benjamin, Van Rheenen Jacco, Hannezo, Edouard
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.1921205117

Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids

Author(s): S. Randriamanantsoa, A. Papargyriou, H. C. Maurer, K. Peschke, M. Schuster, G. Zecchin, K. Steiger, R. Öllinger, D. Saur, C. Scheel, R. Rad, E. Hannezo, M. Reichert, A. R. Bausch
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32806-y