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Zooming into the Population History of Iron Age Europe with Rare Genetic Variants.

Descripción del proyecto

Aprender sobre la prehistoria europea a partir de ADN antiguo

El campo interdisciplinar de la arqueogenética (el estudio del ADN antiguo) arrojará luz sobre la prehistoria europea. La homogenización de las poblaciones europeas desde el Neolítico tardío ha sido difícil de rastrear mediante los métodos analíticos actuales. Para abordar esta cuestión, el proyecto MICROSCOPE, financiado con fondos europeos, desarrollará un nuevo conjunto de herramientas (un cúmulo de métodos analíticos bien equilibrados) basado en variaciones genéticas raras. Este «microscopio» genético permitirá el análisis de los datos genómicos antiguos para inferir la estructura de la población con un detalle sin precedentes. Aunque el estudio abarcará desde la Edad del Hierro europea prerromana hasta la actualidad, se centrará en el antiguo mundo celta (con una región central desde Francia hasta Eslovaquia). Además, la reconstrucción de árboles genealógicos mostrará cómo se reflejan las migraciones y los aditivos a la población en los niveles familiar y comunitario.

Objetivo

In recent years, archaeogenetic studies have yielded striking insights into European prehistory from ancient DNA. However, these studies focus on times prior and up to the Bronze Age, whereas more recent periods are still poorly covered. A key challenge with studying more recent time periods is the homogenisation of European populations since the late Neolithic, which exposes the limits of many existing analytical methods that try to detect population movements. To overcome these limits, in this proposal I will develop a genetic 'microscope', a new set of fine-scaled analytical methods based on rare genetic variation, which will allow us to analyse ancient genomic data to infer population structure with unprecedented detail. With this new toolbox, I will undertake the largest archaeogenetic investigation of the pre-Roman European Iron Age to date. A specific focus will be the ‘Celtic’ world, encompassing a core region spanning from parts of France into Slovakia, and which reached its maximum extent in the third century BC, spanning from the Iberian Peninsula to Anatolia. I will collaborate with a large number of partners from archaeology and anthropology, as well as genetic laboratories, to sample and analyse 600 skeletal remains from this region and time period. Using the new methods, I aim to investigate i) population structure during the early Iron Age in the 'Celtic' core region of Western and Central Europe; ii) the genetic evidence for the so-called 'Celtic migrations' from the third century BC, specifically by analysing samples from the Iberian Peninsula, Northern Italy, Hungary/Romania and the British isles; iii) how migration and population admixture are reflected at the community- and family level by ‘zooming in’ into selected archaeological sites to reconstruct family pedigrees. With new methodology, new reference data, and hundreds of ancient genomes from the pre-Roman Iron Age, this project will set new standards for archaeogenetic studies in Europe.

Régimen de financiación

ERC-STG - Starting Grant

Institución de acogida

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Aportación neta de la UEn
€ 1 495 161,00
Dirección
HOFGARTENSTRASSE 8
80539 Munchen
Alemania

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Región
Bayern Oberbayern München, Kreisfreie Stadt
Tipo de actividad
Research Organisations
Enlaces
Coste total
€ 1 495 161,00

Beneficiarios (1)