Celluloepidemiology: a novel paradigm for modeling T-cell responses on a population level.

Project Information

CELLULO-EPI

Grant agreement ID: 851752

DOI

10.3030/851752

Project closed

EC signature date 12 February 2020

Start date 1 March 2020

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 734,00

EU contribution

€ 1 499 734,00

Coordinated by

UNIVERSITEIT ANTWERPEN
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Modeling antibody dynamics following herpes zoster indicates that higher varicella-zoster virus viremia generates more VZV-specific antibodies

Author(s): Hajar Besbassi, Irene Garcia-Fogeda, Mark Quinlivan, Judy Breuer, Steven Abrams, Niel Hens, Benson Ogunjimi, Philippe Beutels
Published in: Frontiers in Immunology, Issue 14, 2023, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2023.1104605

Unravelling the immune signature of herpes zoster: Insights into pathophysiology and the HLA risk profile

Author(s): R. Vandoren, M. Boeren, Jolien Schippers, E. Bartholomeus, K. Mullan, N. Michels, O. Aerts, J. Leysen, A. Bervoets, J. Lambert, E. Leuridan, J. Wens, Karin Peeters, MP. Emonds, H. Jansens, JL. Casanova, P. Bastard, A. Suls, V. Van Tendeloo, P. Ponsaerts, P. Delputte, Benson Ogunjimi, K. Laukens, Pieter Meysman
Published in: The Journal of Infectious Diseases, Issue 229(2), 2024, Page(s) 507-516, ISSN 0022-1899
Publisher: University of Chicago Press
DOI: 10.1093/infdis/jiad609

Multi-view learning to unravel the different levels underlying hepatitis B vaccine response. Vaccines

Author(s): Fabio Affaticati, E. Bartholomeus, K. Mullan, P. Van Damme, P. Beutels, Benson Ogunjimi, K. Laukens, Pieter Meysman
Published in: Vaccines, 2023, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)

Lack of functional TCR-epitope interaction is associated with herpes zoster through reduced downstream T cell activation

Author(s): Marlies Boeren, Nicky de Vrij, My K. Ha, Sebastiaan Valkiers, Aisha Souquette, Sofie Gielis, Maria Kuznetsova, Jolien Schippers, Esther Bartholomeus, Johan Van den Bergh, Nele Michels, Olivier Aerts, Julie Leysen, An Bervoets, Julien Lambert, Elke Leuridan, Johan Wens, Karin Peeters, Marie-Paule Emonds, George Elias, Niels Vandamme, Hilde Jansens, Wim Adriaensen, Arvid Suls, Stijn Vanhee, Niel Hen
Published in: Cell Reports, Issue 43, 2024, Page(s) 114062, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2024.114062

Within-host mathematical models to study antibody kinetics after the prophylactic Ebola vaccine in the Democratic Republic of the Congo

Author(s): Irene Garcia-Fogeda, Steven Abrams, Stijn Vanhee, Maha Salloum, Benson Ogunjimi, Niel Hens
Published in: Vaccine, Issue 64, 2025, Page(s) 127707, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2025.127707

Multi-view learning to unravel the different levels underlying hepatitis B vaccine response

Author(s): Fabio Affaticati, Esther Bartholomeus, Kerry Mullan, Pierre Van Damme, Philippe Beutels, Benson Ogunjimi, Kris Laukens, Pieter Meysman
Published in: Vaccines, 2024, ISSN 2076-393X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.1101/2023.02.23.529670

Modeling Antigen-Specific T Cell Dynamics Following Hepatitis B Vaccination indicates differences between conventional and regulatory T cell dynamics

Author(s): Hajar Besbassi, George Elias, Pieter Meysman, Hilde Jansens, Kris Laukens, Pierre Van Damme, Niel Hens, Philippe Beutels, Benson Ogunjimi
Published in: Vaccine, 2023, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1101/2023.05.27.542434

Celluloepidemiology—A paradigm for quantifying infectious disease dynamics on a population level

Author(s): My K. Ha, Anna Postovskaya, Maria Kuznetsova, Pieter Meysman, Vincent Van Deuren, Sabrina Van Ierssel, Hans De Reu, Jolien Schippers, Karin Peeters, Hajar Besbassi, Leo Heyndrickx, Betty Willems, Joachim Mariën, Esther Bartholomeus, Koen Vercauteren, Philippe Beutels, Pierre Van Damme, Eva Lion, Erika Vlieghe, Kris Laukens, Samuel Coenen, Reinout Naesens, Kevin K. Ariën, Benson Ogunjimi
Published in: Science Advances, Issue 11, 2025, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.adt2926

Modeling antibody dynamics following herpes zoster indicates that higher varicella-zoster virus (VZV) viremia generates more VZV-specific antibodies

Author(s): Hajar Besbassi, Irene Garcia-Fogeda, Mark Quinlivan, Judy Breuer, Stevens Abrams, Niel Hens*, Benson Ogunjimi* & Philippe Beutels*.*equal contribution
Published in: Frontiers in Immunology, 2023, ISSN 1664-3224
Publisher: Frontiers

"Modeling antigen-specific <mml:math xmlns:mml=""http://www.w3.org/1998/Math/MathML"" altimg=""si66.svg"" display=""inline"" id=""d1e1296""><mml:mi>T</mml:mi></mml:math> cell dynamics following Hepatitis B Vaccination indicates differences between conventional and regulatory <mml:math xmlns:mml=""http://www.w3.org/1998/Math/MathML"" altimg=""si66.svg"" display=""inline"" id=""d1e1301""><mml:mi>T</mml:mi></mml:math"

Author(s): Hajar Besbassi, George Elias, Pieter Meysman, Hilde Jansens, Kris Laukens, Pierre Van Damme, Niel Hens, Philippe Beutels, Benson Ogunjimi
Published in: Vaccine, Issue 42, 2024, Page(s) 126148, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2024.07.049

Within-host modeling to measure dynamics of antibody responses after natural infection or vaccination: A systematic review.

Author(s): Irene Garcia-Fogeda, Hajar Besbassi, Ynke Lariviere, Benson Ogunjimi, Steven Abrams & Niel Hens
Published in: Vaccine, 2023, ISSN 0264-410X
Publisher: Elsevier BV
DOI: 10.1016/j.vaccine.2023.04.030

Other (4)

Linking myelin and Epstein-Barr virus specific immune responses in multiple sclerosis: insights from integrated public T cell receptor repertoires

Author(s): Sebastiaan Valkiers, Amber Dams, Maria Kuznetsova, My Ha, Ibo Janssens, Barbara Willekens, Kris Laukens, Benson Ogunjimi, Nathalie Cools, Pieter Meysman
Published in: biorxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.23.619834

Bridging immunotypes and enterotypes using a systems immunology approach

Author(s): Fabio Affaticati, My K. Ha, Thies Gehrmann, Ilke De Boeck, Maria Kuznetsova, Romi Vandoren, Vincent Van Deuren, Hilde Jansens, Hans De Reu, Jolien Schippers, Karin Peeters, Esther Bartholomeus, Sabrina Van Ierssel, Samuel Coenen, Reinout Naesens, Kevin K. Ariën, Koen Vercauteren, Erika Vlieghe, Philippe Beutels, Pierre Van Damme, Herman Goossens, Eva Lion, Arvid Suls, Sarah Lebeer, Kris Laukens,
Published in: biorxiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.11.29.625344

Generation of a T cell receptor, cytokine and cell repertoire synovial fluid atlas to define commonalities and dissimilarities between arthritic diseases through systems immunology approaches

Author(s): My K. Ha, Vincent Van Deuren, Carlos Alberto de Carvalho Fraga, An Hotterbeekx, Joke Dehoorne, Thomas Renson, Elke Geens, Nicolaas Aerts, Christiaan Heusdens, Maria Kuznetsova, Margot Van Mechelen, Michaël Vanden Bulcke, Ilse Hoffman, Ruth Wittoek, Eva De Wachter, Aurelie Andrzejewski, Esther Bartholomeus, Nick de Vrij, Arvid Suls, Eva Lion, Stijn Vanhee, Wim Adriaensen, Kerry Mullan, Helder Naka
Published in: biorxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.01.10.632345

T cell-microbiome associations captured through T cell receptor convergence analysis

Author(s): Romi Vandoren, My Ha, Vincent Van Deuren, Naomi De Roeck, Ting Pu, Eelco C. Brand, Maria Kuznetsova, Hajar Besbassi, Esther Bartholomeus, Fabio Affaticati, Ilke De Boeck, Thies Gehrmann, Sarah Lebeer, Bas Oldenburg, Femke van Wijk, Peter Delputte, Sara Verbandt, Sabine Tejpar, Kris Laukens, Benson Ogunjimi, Pieter Meysman
Published in: biorxiv, 2025
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.09.30.679432