A new perspective on the metabolic pathway to neuronal dysfunction: Using organs on a chip to elucidate the role of the brain microvasculature

Informazioni relative al progetto

SweetBrain

ID dell’accordo di sovvenzione: 851765

DOI

10.3030/851765

Data della firma CE 2 Ottobre 2019

Data di avvio 1 Settembre 2020

Data di completamento 30 Novembre 2025

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale

€ 1 487 438,00

Contributo UE

€ 1 487 438,00

Coordinato da

TEL AVIV UNIVERSITY
Israel

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Pubblicazioni

Peer reviewed articles (13)

Multi‐Sensor Origami Platform: A Customizable System for Obtaining Spatiotemporally Precise Functional Readouts in 3D Models

Autori: Noam Rahav, Denise Marrero, Adi Soffer, Emma Glickman, Megane Beldjilali‐Labro, Yakey Yaffe, Keshet Tadmor, Yael Leichtmann‐Bardoogo, Uri Ashery, Ben M. Maoz
Pubblicato in: Advanced Science, Numero 11, 2024, ISSN 2198-3844
Editore: wiley publishing
DOI: 10.1002/advs.202305555

Super-Resolution-Chip: an in-vitro platform that enables super-resolution microscopy of co-cultures and 3D systems

Autori: Ofir Sade, Ronja Boneberg, Yifat Weiss, Megane Beldjilali-Labro, Yael Leichtmann-Bardoogo, Itay Talpir, Irit Gottfried, Uri Ashery, Rossana Rauti, Ben M. Maoz
Pubblicato in: Biomedical Optics Express, Numero 14, 2024, Pagina/e 5223, ISSN 2156-7085
Editore: The Optical Society
DOI: 10.1364/boe.498038

Inducing Mechanical Stimuli to Tissues Grown on a Magnetic Gel Allows Deconvoluting the Forces Leading to Traumatic Brain Injury

Autori: Luise Schlotterose, Megane Beldjilali-Labro, Mario Hagel, Moran Yadid, Carina Flaxer, Eli Flaxer, A. Ronny Barnea, Kirsten Hattermann, Esther Shohami, Yael Leichtmann-Bardoogo, Ben M. Maoz
Pubblicato in: Neurotrauma Reports, Numero 4, 2023, Pagina/e 560-572, ISSN 2689-288X
Editore: Mary Ann Liebert, Inc.
DOI: 10.1089/neur.2023.0026

Biology and Models of the Blood–Brain Barrie

Autori: Cynthia Hajal, Baptiste Le Roi, Roger D. Kamm, and Ben M. Maoz
Pubblicato in: Annual Review of Biomedical Engineering, 2021, ISSN 1936-1335
Editore: Annual Reviews A Nonprofit Scientific Publisher
DOI: 10.1146/annurev-bioeng-082120-042814

Traumatic Brain Injury in a Well: A Modular Three-Dimensional Printed Tool for Inducing Traumatic Brain Injury In vitro

Autori: Luise Schlotterose, Megane Beldjilali-Labro, Gaya Schneider, Ofir Vardi, Kirsten Hattermann, Uzi Even, Esther Shohami, Herman D. Haustein, Yael Leichtmann-Bardoogo, and Ben M. M
Pubblicato in: Neurotrauma Reports, Numero Volume: 4 Numero 1: April 20, 2023, 2023, Pagina/e 255-266, ISSN 2689-288X
Editore: Mary Ann Liebert, Inc.
DOI: 10.1089/neur.2022.0072

Effect of SARS-CoV-2 proteins on vascular permeability.

Autori: Rossana Rauti; Meishar Shahoha; Yael Leichtmann-Bardoogo; Rami Nasser; Eyal Paz; Rina Tamir; Victoria Miller; Tal Babich; Kfir Shaked; Avner Ehrlich; Konstantinos Ioannidis; Yaakov Nahmias; Roded Sharan; Uri Ashery; Ben M. Maoz
Pubblicato in: eLife, Numero 1, 2021, ISSN 2050-084X
Editore: eLife Sciences Publications
DOI: 10.7554/elife.69314

Transforming a well into a chip: A modular 3D-printed microfluidic chip.

Autori: Rossana Rauti; Adi Ess; Baptiste Le Roi; Yevgeniy Kreinin; Mark Epshtein; Netanel Korin; Ben M. Maoz
Pubblicato in: APL Bioengineering, Numero 1, 2021, ISSN 2473-2877
Editore: AIP Publishing LLC
DOI: 10.1063/5.0039366

Spatial Trans-Epithelial Electrical Resistance (S-TEER) Integrated in Organs-on-Chips

Autori: Noa Renous; Mark Dan Kiri; Ronny Aharon Barnea; Rossana Rauti; Yael Leichtamnn-Bardoogo; Ben M. Maoz
Pubblicato in: Lab on a Chip, Numero 1, 2022, ISSN 1473-0197
Editore: Royal Society of Chemistry
DOI: 10.1039/d1lc00789k

Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges

Autori: David Yogev, Tomer Goldberg, Amir Arami, Shai Tejman-Yarden, Thomas E. Winkler, Ben M. Maoz
Pubblicato in: APL Bioengineering, Numero 7, 2023, ISSN 2473-2877
Editore: AIP publishing
DOI: 10.1063/5.0152290

Insight on Bacterial Newborn Meningitis Using a Neurovascular-Unit-on-a-Chip

Autori: Rossana Rauti, Sharon Navok, Dvora Biran, Keshet Tadmor, Yael Leichtmann-Bardoogo, Eliora Z. Ron, Ben M. Maoz
Pubblicato in: Microbiology Spectrum, Numero 11, 2023, ISSN 2165-0497
Editore: American Society for Microbiology
DOI: 10.1128/spectrum.01233-23

Technology-based approaches toward a better understanding of neuro-coagulation in brain homeostasis

Autori: Ben M. Maoz, Maria Asplund, Nicola Maggio & Andreas Vlachos
Pubblicato in: Cell and Tissue Research, 2022, ISSN 1432-0878
Editore: Springer Nature
DOI: 10.1007/s00441-021-03560-2

Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system

Autori: Ben M. Maoz
Pubblicato in: APL Bioengineering, Numero 3, 2021, ISSN 2473-2877
Editore: AIP Publishing LLC
DOI: 10.1063/5.0055812

Brain‐Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha‐Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease

Autori: Mor Sela, Maria Poley, Patricia Mora‐Raimundo, Shaked Kagan, Aviram Avital, Maya Kaduri, Gal Chen, Omer Adir, Adi Rozencweig, Yfat Weiss, Ofir Sade, Yael Leichtmann‐Bardoogo, Lilach Simchi, Shlomit Aga‐Mizrachi, Batia Bell, Yoel Yeretz‐Peretz, Aviv Zaid Or, Ashwani Choudhary, Idan Rosh, Diogo Cordeiro, Stav Cohen‐Adiv, Yevgeny Berdichevsky, Anas Odeh, Jeny Shklover, Janna Shainsky‐Roit
Pubblicato in: Advanced Materials, Numero 35, 2024, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202304654