The dark side of evolution: the deleterious mutational landscape of RNA viruses

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Mutation rate, selection, and epistasis inferred from RNA virus haplotypes via neural posterior estimation

Autores: Itamar Caspi, Moran Meir, Nadav Ben Nun, Reem Abu Rass, Uri Yakhini, Adi Stern, Yoav Ram
Publicado en: Virus Evolution, 2023, ISSN 2057-1577
Editor: Oxford university press
DOI: 10.1093/ve/vead033

Drivers of adaptive evolution during chronic SARS-CoV-2 infections

Autores: Sheri Harari, Maayan Tahor, Natalie Rutsinsky, Suzy Meijer, Danielle Miller, Oryan Henig, Ora Halutz, Katia Levytskyi, Ronen Ben-Ami, Amos Adler, Yael Paran & Adi Stern
Publicado en: Nature Medicine, 2022, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-022-01882-4

Evidence for increased breakthrough rates of SARS-CoV-2 variants of concern in BNT162b2-mRNA-vaccinated individuals

Autores: Talia Kustin, Noam Harel, Uriah Finkel, Shay Perchik, Sheri Harari, Maayan Tahor, Itamar Caspi, Rachel Levy, Michael Leshchinsky, Shifra Ken Dror, Galit Bergerzon, Hala Gadban, Faten Gadban, Eti Eliassian, Orit Shimron, Loulou Saleh, Haim Ben-Zvi, Elena Keren Taraday, Doron Amichay, Anat Ben-Dor, Dana Sagas, Merav Strauss, Yonat Shemer Avni, Amit Huppert, Eldad Kepten, Ran D. Balicer, Doron Netzer
Publicado en: Nature Medicine, Edición 27/8, 2021, Página(s) 1379-1384, ISSN 1078-8956
Editor: Nature Publishing Group
DOI: 10.1038/s41591-021-01413-7

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