ERA Chair Position for Excellent Research in Oncology

Livrables

The job ad is aimed to recruit a person who fulfills the following criteria: i) managerial experience from a prestigious academic or life-science industry institution; ii) broad international collaboration with verifiable contacts; iii) leadership of large national, international or European scientific projects; iv) excellent values of scientometric indicators; v) experience with research group or research programs leadership; vi) vast experience with doctoral and post-doctoral mentoring; vii) current scientific activity in genomic cancer research including facilities and competence for DNA sequencing and related bioinformatics. The job advertisement will be published in English language and disseminated by multiple channels for announcement of job positions in research community.

Project Events 2

To ensure the maximum impact and effectiveness of partial steps the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links archive management of the public documents active use of social networks and coordination of shared contributions publication of articles in different electronic media and complex electronic communication during the whole project implementation email skype electronic publication of the Chaperon newsletter on monthly basis All these activities wil be reported to the Project Coordinator

Project Events

To ensure the maximum impact and effectiveness of partial steps, the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links, archive management of the public documents, active use of social networks and coordination of shared contributions, publication of articles in different electronic media and complex electronic communication during the whole project implementation (email, skype), electronic publication of the Chaperon newsletter on monthly basis. All these activities wil be reported to the Project Coordinator.

Plan of dissemination and knowledge transfer

During the M1 M2 individual activities will be planned to disseminate information on the implementation of project actions and the results achieved The Plan for dissemination and knowledge transfer will be periodically every 6 months reevaluated and if necessary modified with the aim of maximizing the impact and success of the planned actions The definitive Plan for dissemination of knowledge transfer will be published in M60 including all operational modifications and changesPlanned submission to EK M3 M7 M60

Final report on evaluation and ERA Chair holder selection

The task leader will elaborate the final report including the text of the vacancy notice, places of publication, composition of the selection panel, CVs of applicants, minutes of selection panel meeting(s) as well as any other document allowing for a full assessment of the openness of the selection procedureof ERA Chair holder selection process at the end of M6.

CUNI recruitment manual

The complete recruitment procedure will be recorded by each procedural step and presented as a feasibility study at the Project Board meeting (M6) and after approval of Project Coordinator disseminated to other faculties of CUNI in order to spread the ERA recruitment principles. This pilot experience will be transferred into an internal recruitment manual to be further applied widely across the faculties and departments of CUNI.

Report on ERA Research Club events

ERA Research Club will be organized under the auspices of the ERA Chair holder as part of the development and support activities of young researchers at CUNI. The progress of the ERA Research club will be reported. Report on ERA Chairs Club Events is intended not only as a summary of the Club Events themselves, but also as a report on their perceived impact on the research environment, including feedback of the attendees etc. Submission to EK M15, 30, 45, 60.

Report on career advisory and Career Development Guidelines

The ERA Chair holder will set up a young researcher counseling platform for career development of novice researchers where they could learn from hisher experience either through focused seminars or personal meetingsThe progress of the career advisory activities will be regularly reported and the last report will include also the final form of the Career Development GuidelinesSubmission to EK M30 45 60

Project Events 1

Official project website

The project website will be created based on the structure defined in the Plan for dissemination of knowledge transfer, including additional tools such as event registration, links with CUNI/FMP/BC websites and internal/employee access portal. The official launch is planned for the M4, with M3-M4 testing and modification period. Templates of project documentation (e.g. presentation, internal report, work and action plans, event invitation and flyer, attendance list) for operational use will be designed and stored for use on implementation on a defined internal portal on the project site.

Publications

Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer

Auteurs: Beiping Miao; Diamanto Skopelitou; Aayushi Srivastava; Sara Giangiobbe; Dagmara Dymerska; Nagarajan Paramasivam; Abhishek Kumar; Magdalena Kuświk; Wojciech Kluźniak; Katarzyna Paszkowska-Szczur; Matthias Schlesner; Jan Lubinski; Kari Hemminki; Asta Försti; Obul Reddy Bandapalli
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031295

<p>Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues</p>

Auteurs: Guoqiao Zheng, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Kari Hemminki
Publié dans: Clinical Epidemiology, Numéro Volume 12, 2020, Page(s) 857-864, ISSN 1179-1349
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/clep.s256662

A Germline Mutation in the POT1 Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer

Auteurs: Aayushi Srivastava, Beiping Miao, Diamanto Skopelitou, Varun Kumar, Abhishek Kumar, Nagarajan Paramasivam, Elena Bonora, Kari Hemminki, Asta Försti, Obul Reddy Bandapalli
Publié dans: Cancers, Numéro 12/6, 2020, Page(s) 1441, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12061441

Bladder and upper urinary tract cancers as first and second primary cancers

Auteurs: Zheng Guoqiao; Sundquist Kristina; Sundquist Jan; Försti Asta; Hemminki Otto; Hemminki Kari Jussi
Publié dans: Cancer reports, 2021, ISSN 2573-8348
Éditeur: Wiley Periodicals, LLC.
DOI: 10.1002/cnr2.1406

Incidence and survival in oral and pharyngeal cancers in Finland and Sweden through half century

Auteurs: Koskinen Anni, I; Hemminki Otto; Forsti Asta; Hemminki Kari Jussi
Publié dans: BMC Cancer, Numéro 14712407, 2022, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/s12885-022-09337-2

The Asthma Family Tree: Evaluating Associations Between Childhood, Parental, and Grandparental Asthma in Seven Chinese Cities

Auteurs: Yu Hongyao; Su Fan; Wang Le-Bing; Hemminki Kari Jussi; Dharmage Shyamali C; Bowatte Gayan; Bui Dinh; Qian Zhengmin; Vaughn Michael G; Aaron Hannah E; Xiong Shimin; Shen Xubo; Zhou Yuanzhong; Zhou Peien; Zeng Xiao-Wen; Chen Gongbo; Yang Bo-Yi; Hu Li-Wen; Dong Guang-Hui
Publié dans: Frontiers in Pediatrics, Numéro 9, 2021, ISSN 2296-2360
Éditeur: Frontiers Media S.A.
DOI: 10.3389/fped.2021.720273

A rare large duplication of MLH1 identified in Lynch syndrome

Auteurs: Abhishek Kumar, Nagarajan Paramasivam, Obul Reddy Bandapalli, Matthias Schlesner, Tianhui Chen, Rolf Sijmons, Dagmara Dymerska, Katarzyna Golebiewska, Magdalena Kuswik, Jan Lubinski, Kari Hemminki, Asta Försti
Publié dans: Hereditary Cancer in Clinical Practice, Numéro 19, 2021, ISSN 1897-4287
Éditeur: BioMed Central Ltd
DOI: 10.1186/s13053-021-00167-0

Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations

Auteurs: Li Xinjun; Sundquist Kristina; Sundquist Jan; Försti Asta; Hemminki Kari Jussi
Publié dans: Scientific Reports, Numéro 20452322, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-90542-7

Association of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With Metastatic Colorectal Cancer

Auteurs: ONDREJ FIALA, ONDREJ SOREJS, PETR HOSEK, VACLAV LISKA, ONDREJ VYCITAL, JAN BRUHA, RADEK KUCERA, ONDREJ TOPOLCAN, JINDRICH FINEK, DIANA MACECKOVA, PAVEL PITULE
Publié dans: Cancer Genomics - Proteomics, Numéro 17/5, 2020, Page(s) 605-613, ISSN 1109-6535
Éditeur: International Institute of Anticancer Research
DOI: 10.21873/cgp.20217

Familial Risks and Proportions Describing Population Landscape of Familial Cancer

Auteurs: Hemminki Kari Jussi; Sundquist Kristina; Sundquist Jan; Foersti Asta; Hemminki Akseli; Li Xinjun
Publié dans: Cancers, Numéro 20726694, 2021, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13174385

Long-term incidence in hepatocellular carcinoma and intrahepatic bile duct cancer in Denmark, Finland, Norway and Sweden, role of Thorotrast?

Auteurs: Kari Hemminki, Filip Tichanek, Asta Försti, Otto Hemminki, Vaclav Liska, Akseli Hemminki
Publié dans: International Journal of Cancer, Numéro 10970215, 2022, ISSN 1097-0215
Éditeur: UICC
DOI: 10.1002/ijc.34031

Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer

Auteurs: Srivastava Aayushi; Giangiobbe Sara; Skopelitou Diamanto; Miao Beiping; Paramasivam Nagarajan; Diquigiovanni Chiara; Bonora Elena; Hemminki Kari Jussi; Försti Asta; Bandapalli Obul Reddy
Publié dans: Frontiers in Endocrinology, 2021, ISSN 1664-2392
Éditeur: Frontiers Media SA
DOI: 10.3389/fendo.2021.600682

Familial Risks between Pernicious Anemia and Other Autoimmune Diseases in the Population of Sweden

Auteurs: Xinjun Li, Hauke Thomsen, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: Autoimune Diseases, 2021, ISSN 2090-0422
Éditeur: Hindawi Publishing Corporation
DOI: 10.1155/2021/8815297

Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer.

Auteurs: Diamanto Skopelitou; Beiping Miao; Aayushi Srivastava; Abhishek Kumar; Abhishek Kumar; Magdalena Kuswick; Dagmara Dymerska; Nagarajan Paramasivam; Matthias Schlesner; Jan Lubinski; Kari Hemminki; Kari Hemminki; Asta Försti; Obul Reddy Bandapalli
Publié dans: International Journal of Molecular Sciences, Numéro 5, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22041837

Survival in colon and rectal cancers in Finland and Sweden through 50 years

Auteurs: Hemminki Kari Jussi; Försti Asta; Hemminki Akseli
Publié dans: BMJ Open Gastroenterology, Numéro 20544774, 2021, ISSN 2054-4774
Éditeur: BMJ Publishing Group Ltd
DOI: 10.1136/bmjgast-2021-000644

Long-term incidence and survival trends in cancer of the gallbladder and extrahepatic bile ducts in Denmark, Finland, Norway and Sweden with etiological implications related to Thorotrast

Auteurs: Hemminki Kari Jussi; Försti Asta; Hemminki Otto; Liška Václav; Hemminki Akse
Publié dans: International Journal of Cancer, Numéro 151/2, 2022, ISSN 1097-0215
Éditeur: Union for International Cancer Control (UICC)
DOI: 10.1002/ijc.33980

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases

Auteurs: Hemminki Kari Jussi; Försti Asta; Houlston Richard; Sud Amit
Publié dans: International Journal of Cancer, Numéro 10970215, 2021, ISSN 1097-0215
Éditeur: UICC
DOI: 10.1002/ijc.33762

Familial associations for rheumatoid autoimmune diseases

Auteurs: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: Rheumatology Advances in Practice, Numéro 4/2, 2020, ISSN 2514-1775
Éditeur: Oxford University Press
DOI: 10.1093/rap/rkaa048

Survival in bladder and upper urinary tract cancers in Finland and Sweden through 50 years

Auteurs: Kari Hemminki; Asta Försti; Akseli Hemminki; Börje Ljungberg, Otto Hemminki
Publié dans: Plos One, Numéro 19326203, 2022, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0261124

Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment

Auteurs: Kari Hemminki; Anna Kanerva; Asta Försti; Akseli Hemminki
Publié dans: BMC Cancer, Numéro 14712407, 2022, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/s12885-022-09582-5

DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations

Auteurs: Niazi Yasmeen; Thomsen Hauke; Smolkova Bozena; Vodičková Ludmila; Vodenková Soňa; Kroupa Michal; Vymetálková Veronika; Kazimirova Alena; Barancokova Magdalena; Volkovova Katarina; Staruchova Marta; Hoffmann Per; Noethen Markus M; Dusinska Maria; Musak Ludovit; Vodička Pavel; Hemminki Kari Jussi; Foersti Asta
Publié dans: Frontiers in Genetics, Numéro 12, 2021, ISSN 1664-8021
Éditeur: Frontiers Media
DOI: 10.3389/fgene.2021.691947

Cancer Predisposition Genes in Cancer-Free Families

Auteurs: Guoqiao Zheng, Calogerina Catalano, Obul Reddy Bandapalli, Nagarajan Paramasivam, Subhayan Chattopadhyay, Matthias Schlesner, Rolf Sijmons, Akseli Hemminki, Dagmara Dymerska, Jan Lubinski, Kari Hemminki, Asta Försti
Publié dans: Cancers, Numéro 12/10, 2020, Page(s) 2770, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12102770

Incidence and survival in laryngeal and lung cancers in Finland and Sweden through a half century

Auteurs: Anni Koskinen,Otto Hemminki,Asta Försti,Kari Hemminki
Publié dans: Plos One, Numéro 19326203, 2022, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0268922

Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition

Auteurs: Jungwirth Jiří; Urbanová Markéta; Boot Arnoud; Hošek Petr; Bendová Petra; Šišková Anna; Švec Jiří; Kment Milan; Tůmová Daniela; Summerová Sandra; Beneš Zdeněk; Büchler Tomáš; Kohout Pavel; Hucl Tomáš; Matěj Radoslav; Vodičková Ludmila; van Wezel Tom; Vodička Pavel; Vymetálková Veronika
Publié dans: Scientific Reports, Numéro 12/1, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-06498-9

Family History of Head and Neck Cancers

Auteurs: Li Xinjun; Koskinen Anni I; Hemminki Otto; Försti Asta; Sundquist Jan; Sundquist Kristina; Hemminki Kari Jussi
Publié dans: Cancers, Numéro 13/16, 2021, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13164115

Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts

Auteurs: Sainz Juan; García-Verdejo Francisco José; Martínez-Bueno Manuel; Kumar Abhishek; Sánchez-Maldonado José Manuel; Díez-Villanueva Anna; Vodičková Ludmila; Vymetálková Veronika; Sánchez Vicente Martin; Da Silva Filho Miguel Inacio; Sampaio-Marques Belém; Brezina Stefanie; Butterbach Katja; Horst Rob ter; Hoffmeister Michael; Ludovico Paula; Jurado Manuel; Li Yang; Sánchez-Rovira Pedro;
Publié dans: Cancers, Numéro 13/6, 2021, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13061258

Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers

Auteurs: Zheng Guoqiao; Sundquist Kristina; Sundquist Jan; Chen Tianhui; Foersti Asta; Hemminki Otto; Hemminki Kari
Publié dans: EUROPEAN UROLOGY OPEN SCIENCE, 2021, ISSN 2666-1683
Éditeur: Elsevier B.V.
DOI: 10.1016/j.euros.2020.12.007

A large-scale assay library for targeted protein quantification in renal cell carcinoma tissues

Auteurs: Lapcik Petr; Janacova Lucia; Bouchalova Pavla; Potesil David; Podhorec Jan; Hora Milan; Poprach Alexandr; Fiala Ondřej; Bouchal Pavel
Publié dans: Proteomics, 2021, ISSN 1615-9861
Éditeur: Wiley-VCH GmbH
DOI: 10.1002/pmic.202100228

A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer

Auteurs: Skopelitou Diamanto; Miao Beiping; Srivastava Aayushi; Kumar Abhishek; Kuswik Magdalena; Dymerska Dagmara; Paramasivam Nagarajan; Schlesner Matthias; Lubinski Jan; Hemminki Kari Jussi; Foersti Asta; Bandapalli Obul Reddy
Publié dans: Journal of Personalized Medicine, Numéro 11/4, 2021, ISSN 2075-4426
Éditeur: MDPI
DOI: 10.3390/jpm11040262

Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor

Auteurs: Hemminki Kari Jussi; Försti Asta; Hemminki Akseli; Ljungberg Börje; Hemminki Otto
Publié dans: BMC Cancer, Numéro 14712407, 2021, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/s12885-021-08371-w

Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib

Auteurs: Fiala Ondřej; Ostašov Pavel; Rozsypalová Aneta; Hora Milan; Šorejs Ondřej; Šustr Jan; Bendová Barbora; Trávníček Ivan; Filipovský Jan; Fínek Jindřich; Büchler Tomáš
Publié dans: Cancer Management and Research, Numéro 11791322, 2021, ISSN 1179-1322
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/cmar.s305321

Octreotide in the treatment of malignant thymoma - Case report

Auteurs: Šorejs Ondřej; Pešek Miloš; Fínek Jindřich; Fiala Ondřej
Publié dans: Reports of Practical Oncology and Radiotherapy, Numéro 25/6, 2020, ISSN 1507-1367
Éditeur: Elsevier Urban/Partner Sp. z.o.o.
DOI: 10.1016/j.rpor.2020.08.012

Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis

Auteurs: Khandanpour Cyrus; Eisfeld Christine; Nimmagadda Subbaiah Chary; Raab Marc S.; Weinhold Niels; Seckinger Anja; Hose Dirk; Jauch Anna; Foersti Asta; Hemminki Kari Jussi; Hielscher Thomas; Hummel Manuela; Lenz Georg; Goldschmidt Hartmut; Huhn Stefanie
Publié dans: Frontiers in Oncology, Numéro 11, 2021, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2021.757664

Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example

Auteurs: Kari Hemminki, Aayushi Srivastava, Sivaramakrishna Rachakonda, Obul Bandapalli, Eduardo Nagore, Akseli Hemminki, Rajiv Kumar
Publié dans: Hereditary Cancer in Clinical Practice, Numéro 18/1, 2020, Page(s) 1-6, ISSN 1897-4287
Éditeur: BioMed Central Ltd
DOI: 10.1186/s13053-020-00146-x

Outcomes According to MSKCC Risk Score with Focus on the Intermediate-Risk Group in Metastatic Renal Cell Carcinoma Patients Treated with First-Line Sunitinib: A Retrospective Analysis of 2390 Patients

Auteurs: Fiala Ondřej; Fínek Jindřich; Poprach Alexandr; Melichar Bohuslav; Kopecký Jindřich; Zemanová Milada; Kopečková Kateřina; Mlcoch Tomas; Dolezal Tomas; Capkova Lenka; Büchler Tomáš
Publié dans: Cancers, Numéro 12/4, 2020, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040808

Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients

Auteurs: Kroupa Michal; Rachakonda Sivaramakrishna; Vymetálková Veronika; Tomášová Kristýna; Liška Václav; Vodenková Soňa; Čumová Andrea; Rossnerová Andrea; Vodičková Ludmila; Hemminki Kari Jussi; Souček Pavel; Kumar Rajiv; Vodička Pavel
Publié dans: Mutagenesis, Numéro 6/35, 2020, ISSN 0267-8357
Éditeur: Oxford University Press
DOI: 10.1093/mutage/geaa030

Incidence, mortality and survival in malignant pleural mesothelioma before and after asbestos in Denmark, Finland, Norway and Sweden

Auteurs: Hemminki Kari Jussi; Forsti Asta; Chen Tianhui; Hemminki Akseli
Publié dans: BMC Cancer, Numéro 21, 2021, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/s12885-021-08913-2

Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer

Auteurs: Skopelitou Diamanto; Srivastava Aayushi; Miao Beiping; Kumar Abhishek; Dymerska Dagmara; Paramasivam Nagarajan; Schlesner Matthias; Lubinski Jan; Hemminki Kari Jussi; Försti Asta; Reddy Bandapalli Obul
Publié dans: Molecular Genetics and Genomics, Numéro 16174615, 2022, ISSN 1617-4615
Éditeur: Springer Verlag
DOI: 10.1007/s00438-022-01896-0

Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016

Auteurs: Hemminki Kari Jussi; Försti Asta; Hansson Markus
Publié dans: Scientific Reports, Numéro 20452322, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-96804-8

Characterization of rare germline variants in familial multiple myeloma

Auteurs: Catalano Calogerina; Paramasivam Nagarajan; Blocka Joanna; Giangiobbe Sara; Huhn Stefanie; Schlesner Matthias; Weinhold Niels; Sijmons Rolf; de Jong Mirjam; Langer Christian; Preuss Klaus-Dieter; Nilsson Björn; Durie Brian; Goldschmidt Hartmut; Bandapalli Obul Reddy; Hemminki Kari Jussi; Försti Asta
Publié dans: Blood Cancer Journal, Numéro 11, 2021, ISSN 2044-5385
Éditeur: Nature Publishing Group
DOI: 10.1038/s41408-021-00422-6

Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Auteurs: Alison P. Klein, Brian M. Wolpin, Harvey A. Risch, Rachael Z. Stolzenberg-Solomon, Evelina Mocci, Mingfeng Zhang, Federico Canzian, Erica J. Childs, Jason W. Hoskins, Ashley Jermusyk, Jun Zhong, Fei Chen, Demetrius Albanes, Gabriella Andreotti, Alan A. Arslan, Ana Babic, William R. Bamlet, Laura Beane-Freeman, Sonja I. Berndt, Amanda Blackford, Michael Borges, Ayelet Borgida, Paige M. Bracci, Laur
Publié dans: Nature Communications, Numéro 9/1, 2018, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-018-02942-5

Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

Auteurs: Antonia Rotolo, Valentina S. Caputo, Monika Holubova, Nicoleta Baxan, Olivier Dubois, Mohammed Suhail Chaudhry, Xiaolin Xiao, Katerina Goudevenou, David S. Pitcher, Kyriaki Petevi, Carolina Kachramanoglou, Sandra Iles, Kikkeri Naresh, John Maher, Anastasios Karadimitris
Publié dans: Cancer Cell, Numéro 34/4, 2018, Page(s) 596-610.e11, ISSN 1535-6108
Éditeur: Cell Press
DOI: 10.1016/j.ccell.2018.08.017

Familial risks between giant cell arteritis and Takayasu arteritis and other autoimmune diseases in the population of Sweden

Auteurs: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: Scientific Reports, Numéro 10, 2020, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-020-77857-7

DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population

Auteurs: NIAZI, Yasmeen; THOMSEN, Hauke; SMOLKOVA, Bozena; VODIČKOVÁ, Ludmila; VODENKOVÁ, Soňa; KROUPA, Michal; VYMETÁLKOVÁ, Veronika; KAZIMIROVA, Alena; BARANCOKOVA, Magdalena; VOLKOVOVA, Katarina; STARUCHOVA, Marta; HOFFMANN, Per; NÖTHEN, Markus M; DUSINSKA, Maria; MUSAK, Ludovit; VODIČKA, Pavel; FÖRSTI, Asta; HEMMINKI, Kari Jussi
Publié dans: DNA Repair, Numéro 101, 2021, ISSN 1568-7864
Éditeur: Elsevier BV
DOI: 10.1016/j.dnarep.2021.103079

Search for AL amyloidosis risk factors using Mendelian randomization

Auteurs: Saunders Charlie N; Chattopadhyay Subhayan; Huhn Stefanie; Weinhold Niels; Hoffmann Per; Noethen Markus M; Joeckel Karl-Heinz; Schmidt Boerge; Landi Stefano; Goldschmidt Hartmut; Milani Paolo; Merlini Giampaolo; Rowcieno Dorota; Hawkins Philip; Hegenbart Ute; Palladini Giovanni; Wechalekar Ashutosh; Schoenland Stefan O; Foersti Asta; Houlston Richard; Hemminki Kari Jussi
Publié dans: Blood Advances, Numéro 20445385, 2021, ISSN 2044-5385
Éditeur: Nature Publishing Group
DOI: 10.1182/bloodadvances.2021004423

Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor

Auteurs: Guoqiao Zheng, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Kari Hemminki
Publié dans: Cancer Medicine, Numéro 9/21, 2020, Page(s) 8258-8265, ISSN 2045-7634
Éditeur: John Wiley & Sons
DOI: 10.1002/cam4.3454

Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden

Auteurs: Hemminki Kari Jussi; Foersti Asta; Hemminki Akseli; Ljungberg Boerje; Hemminki Otto
Publié dans: PLoS One, Numéro 19326203, 2021, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0253236

Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers

Auteurs: Zheng Guoqiao; Sundquist Kristina; Sundquist Jan; Chen Tianhui; Forsti Asta; Hemminki Akseli; Liška Václav; Hemminki Kari Jussi
Publié dans: Clinical Epidemiology, Numéro 11791349, 2021, ISSN 1179-1349
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/clep.s318737

Familial Risks for Liver, Gallbladder and Bile Duct Cancers and for Their Risk Factors in Sweden, a Low-Incidence Country

Auteurs: Kari Hemminki; Kristina Sundquist; Jan Sundquist; Asta Försti; Vaclav Liska; Akseli Hemminki; Xinjun Li
Publié dans: Cancers, Numéro 20726694, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14081938

Germline Variants of CYBA and TRPM4 Predispose to Familial Colorectal Cancer

Auteurs: Lizhen Zhu; Beiping Miao; Dagmara Dymerska; Magdalena Kuswik; Elena Bueno-Martínez; Lara Sanoguera-Miralles; Eladio A Velasco; Nagarajan Paramasivam; Matthias Schlesner; Abhishek Kumar; Ying Yuan; Jan Lubinski; Obul Reddy Bandapalli; Kari Hemminki; Asta Försti
Publié dans: Cancers, Numéro 20726694, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14030670

Familial associations for Addison's disease and between Addison's disease and other autoimmune diseases

Auteurs: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: Endocrine Connections, Numéro 9/11, 2020, Page(s) 1114–1120, ISSN 2049-3614
Éditeur: BioScientifica Ltd.
DOI: 10.1530/ec-20-0328

Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases

Auteurs: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: PLOS ONE, Numéro 15/10, 2020, Page(s) e0240794, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0240794

Types of second primary cancer influence overall survival in cutaneous melanoma

Auteurs: Zheng Guoqiao; Chattopadhyay Subhayan; Sundquist Kristina; Sundquist Jan; Foersti Asta; Hemminki Akseli; Hemminki Kari Jussi
Publié dans: BMC Cancer, Numéro 21/1, 2021, ISSN 1471-2407
Éditeur: BioMed Central
DOI: 10.1186/s12885-021-08845-x

Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden

Auteurs: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Publié dans: Journal of Translational Autoimmunity, Numéro 3, 2020, Page(s) 100058, ISSN 2589-9090
Éditeur: Elsevier
DOI: 10.1016/j.jtauto.2020.100058

Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer

Auteurs: Zheng Guoqiao; Sundquist Kristina; Sundquist Jan; Chen Tianhui; Foersti Asta; Hemminki Akseli; Hemminki Kari Jussi
Publié dans: Clinical Epidemiology, Numéro 13, 2021, ISSN 1179-1349
Éditeur: Dove Medical Press Ltd
DOI: 10.2147/clep.s304332

T- and B-Cells in the Inner Invasive Margin of Hepatocellular Carcinoma after Resection Associate with Favorable Prognosis

Auteurs: Trailin Andriy; Červenková Lenka; Ambrożkiewicz Filip; Sobhe Abdelhamid Mahmoud Esraa; Kasi Phanindra Babu; Pálek Richard; Hošek Petr; Třeška Vladislav; Daum Ondřej; Tonar Zbyněk; Liška Václav; Hemminki Kari Jussi
Publié dans: Cancers, Numéro 20726694, 2022, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14030604

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