ERA Chair Position for Excellent Research in Oncology

Informacje na temat projektu

Chaperon

Identyfikator umowy o grant: 856620

DOI

10.3030/856620

Projekt został zamknięty

Data podpisania przez KE 25 Czerwca 2019

Data rozpoczęcia 1 Sierpnia 2019

Data zakończenia 31 Lipca 2024

Finansowanie w ramach

• Establishing ‚ERA Chairs’

Koszt całkowity

€ 2 487 241,25

Wkład UE

€ 2 487 241,25

Koordynowany przez

UNIVERZITA KARLOVA
Czechia

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (15)

Job advertisment

The job ad is aimed to recruit a person who fulfills the following criteria: i) managerial experience from a prestigious academic or life-science industry institution; ii) broad international collaboration with verifiable contacts; iii) leadership of large national, international or European scientific projects; iv) excellent values of scientometric indicators; v) experience with research group or research programs leadership; vi) vast experience with doctoral and post-doctoral mentoring; vii) current scientific activity in genomic cancer research including facilities and competence for DNA sequencing and related bioinformatics. The job advertisement will be published in English language and disseminated by multiple channels for announcement of job positions in research community.

Project Events 2

To ensure the maximum impact and effectiveness of partial steps the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links archive management of the public documents active use of social networks and coordination of shared contributions publication of articles in different electronic media and complex electronic communication during the whole project implementation email skype electronic publication of the Chaperon newsletter on monthly basis All these activities wil be reported to the Project Coordinator

Sustainability plan

The sustainability plan will help to exploit the benefits acquired during the ERA Chair holder engagement. Sustainability plan will also include dissemination measures designed for each priority domain for the period after the project termination. Sustainability plan for the period of 4 years after the project termination will be developed mainly in the following areas: i) subsequent, further internal research, career development of researchers with emphasis on international mobility of researchers, ii) institutional and competitive funding on national and international level, focused on participation in international research consortiums, iii) development of methodologies in grant applications preparation, knowledge share, contacts and research collaborations, and iv) standardization of activities on the level of strategic management.

Project Events

To ensure the maximum impact and effectiveness of partial steps, the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links, archive management of the public documents, active use of social networks and coordination of shared contributions, publication of articles in different electronic media and complex electronic communication during the whole project implementation (email, skype), electronic publication of the Chaperon newsletter on monthly basis. All these activities wil be reported to the Project Coordinator.

Plan of dissemination and knowledge transfer

During the M1 M2 individual activities will be planned to disseminate information on the implementation of project actions and the results achieved The Plan for dissemination and knowledge transfer will be periodically every 6 months reevaluated and if necessary modified with the aim of maximizing the impact and success of the planned actions The definitive Plan for dissemination of knowledge transfer will be published in M60 including all operational modifications and changesPlanned submission to EK M3 M7 M60

Report on scientific publications

The task leader will provide internal annual reports of research groupachievements to the Project Coordinator and the reporting will be presented at the Advisory Team meetings. Research outputs of the team will be published in scientific peer-review journals in the corresponding fields in form of scientific publications.

Final report on evaluation and ERA Chair holder selection

The task leader will elaborate the final report including the text of the vacancy notice, places of publication, composition of the selection panel, CVs of applicants, minutes of selection panel meeting(s) as well as any other document allowing for a full assessment of the openness of the selection procedureof ERA Chair holder selection process at the end of M6.

Summary of improvement proposals

ERA Chair will identify weaknesses in management processes that hamper more efficient multi-level functioning and present improvement proposals within T4.2, building on the experience of his/her previous top-level positions at international institutions. The proposed improvements will be presented and discussed at the regular meetings of Dean's Advisory Board and Scientific Council.Measures to transfer good practices and extensive experience through improvement suggestions at the institutional advisory level will be complemented by personal meetings with representatives of individual institutional areas at the level of university, faculty and the research center management. The individual reports on coordination meetings will be matter of internal reporting towards the Project Coordinator.

Plan of cooperation with private sector and networking events

List of companies and cooperation offers to be further developed by representatives of specific projects of technology transfer with support of ERA Chair holder and the Center,and plan for further networking events

CUNI recruitment manual

The complete recruitment procedure will be recorded by each procedural step and presented as a feasibility study at the Project Board meeting (M6) and after approval of Project Coordinator disseminated to other faculties of CUNI in order to spread the ERA recruitment principles. This pilot experience will be transferred into an internal recruitment manual to be further applied widely across the faculties and departments of CUNI.

Report on ERA Research Club events

ERA Research Club will be organized under the auspices of the ERA Chair holder as part of the development and support activities of young researchers at CUNI. The progress of the ERA Research club will be reported. Report on ERA Chairs Club Events is intended not only as a summary of the Club Events themselves, but also as a report on their perceived impact on the research environment, including feedback of the attendees etc. Submission to EK M15, 30, 45, 60.

Report on career advisory and Career Development Guidelines

The ERA Chair holder will set up a young researcher counseling platform for career development of novice researchers where they could learn from hisher experience either through focused seminars or personal meetingsThe progress of the career advisory activities will be regularly reported and the last report will include also the final form of the Career Development GuidelinesSubmission to EK M30 45 60

Project Events 4

To ensure the maximum impact and effectiveness of partial steps, the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links, archive management of the public documents, active use of social networks and coordination of shared contributions, publication of articles in different electronic media and complex electronic communication during the whole project implementation (email, skype), electronic publication of the Chaperon newsletter on monthly basis. All these activities wil be reported to the Project Coordinator.

Project Events 1

To ensure the maximum impact and effectiveness of partial steps the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links archive management of the public documents active use of social networks and coordination of shared contributions publication of articles in different electronic media and complex electronic communication during the whole project implementation email skype electronic publication of the Chaperon newsletter on monthly basis All these activities wil be reported to the Project Coordinator

Project Events 3

To ensure the maximum impact and effectiveness of partial steps, the realization of dissemination activities under this task will focus on periodical update of project websites and corresponding links, archive management of the public documents, active use of social networks and coordination of shared contributions, publication of articles in different electronic media and complex electronic communication during the whole project implementation (email, skype), electronic publication of the Chaperon newsletter on monthly basis. All these activities wil be reported to the Project Coordinator.

Websites, patent fillings, videos etc. (1)

Official project website

The project website will be created based on the structure defined in the Plan for dissemination of knowledge transfer, including additional tools such as event registration, links with CUNI/FMP/BC websites and internal/employee access portal. The official launch is planned for the M4, with M3-M4 testing and modification period. Templates of project documentation (e.g. presentation, internal report, work and action plans, event invitation and flyer, attendance list) for operational use will be designed and stored for use on implementation on a defined internal portal on the project site.

Publikacje

Peer reviewed articles (102)

Whole-Exome Sequencing Identifies a Novel Germline Variant in PTK7 Gene in Familial Colorectal Cancer

Autorzy: Beiping Miao; Diamanto Skopelitou; Aayushi Srivastava; Sara Giangiobbe; Dagmara Dymerska; Nagarajan Paramasivam; Abhishek Kumar; Magdalena Kuświk; Wojciech Kluźniak; Katarzyna Paszkowska-Szczur; Matthias Schlesner; Jan Lubinski; Kari Hemminki; Asta Försti; Obul Reddy Bandapalli
Opublikowane w: International Journal of Molecular Sciences, Numer 14220067, 2022, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031295

Emerging role of circulating cell-free RNA as a non-invasive biomarker for hepatocellular carcinoma

Autorzy: Dattatrya Shetti, Venkata Ramana Mallela, Wenjing Ye, Mahyar Sharif, Filip Ambrozkiewicz, Andriy Trailin, Václav Liška, Kari Hemminki
Opublikowane w: Critical Reviews in Oncology/Hematology, Numer 200, 2024, Strona(/y) 104391, ISSN 1040-8428
Wydawca: Elsevier BV
DOI: 10.1016/j.critrevonc.2024.104391

An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay

Autorzy: Pavel Vodicka, Sona Vodenkova, Josef Horak, Alena Opattova, Kristyna Tomasova, Veronika Vymetalkova, Rudolf Stetina, Kari Hemminki, Ludmila Vodickova
Opublikowane w: Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Numer 885, 2024, Strona(/y) 503564, ISSN 1383-5718
Wydawca: Elsevier BV
DOI: 10.1016/j.mrgentox.2022.503564

<p>Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues</p>

Autorzy: Guoqiao Zheng, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Kari Hemminki
Opublikowane w: Clinical Epidemiology, Numer Volume 12, 2020, Strona(/y) 857-864, ISSN 1179-1349
Wydawca: Dove Medical Press Ltd
DOI: 10.2147/clep.s256662

A Germline Mutation in the POT1 Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer

Autorzy: Aayushi Srivastava, Beiping Miao, Diamanto Skopelitou, Varun Kumar, Abhishek Kumar, Nagarajan Paramasivam, Elena Bonora, Kari Hemminki, Asta Försti, Obul Reddy Bandapalli
Opublikowane w: Cancers, Numer 12/6, 2020, Strona(/y) 1441, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12061441

Bladder and upper urinary tract cancers as first and second primary cancers

Autorzy: Zheng Guoqiao; Sundquist Kristina; Sundquist Jan; Försti Asta; Hemminki Otto; Hemminki Kari Jussi
Opublikowane w: Cancer reports, 2021, ISSN 2573-8348
Wydawca: Wiley Periodicals, LLC.
DOI: 10.1002/cnr2.1406

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?

Autorzy: Antonio José Cabrera-Serrano, José Manuel Sánchez-Maldonado, Rob ter Horst, Angelica Macauda, Paloma García-Martín, Yolanda Benavente, Stefano Landi, Alyssa Clay-Gilmour, Yasmeen Niazi, Blanca Espinet, Juan José Rodríguez-Sevilla, Eva María Pérez, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, James R. Cerhan, Roberto Marasca, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen
Opublikowane w: International Journal of Molecular Sciences, Numer 24, 2023, Strona(/y) 8005, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24098005

Survival in Lung Cancer in the Nordic Countries Through A Half Century

Autorzy: Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki, Kari Hemminki
Opublikowane w: Clinical Epidemiology, Numer Volume 15, 2023, Strona(/y) 503-510, ISSN 1179-1349
Wydawca: Dove Medical Press Ltd
DOI: 10.2147/clep.s406606

Incidence and survival in oral and pharyngeal cancers in Finland and Sweden through half century

Autorzy: Koskinen Anni, I; Hemminki Otto; Forsti Asta; Hemminki Kari Jussi
Opublikowane w: BMC Cancer, Numer 14712407, 2022, ISSN 1471-2407
Wydawca: BioMed Central
DOI: 10.1186/s12885-022-09337-2

Survival in Colon, Rectal and Small Intestinal Cancers in the Nordic Countries through a Half Century

Autorzy: Filip Tichanek, Asta Försti, Vaclav Liska, Akseli Hemminki, Kari Hemminki
Opublikowane w: Cancers, Numer 15, 2023, Strona(/y) 991, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15030991

miRNA and lncRNA as potential tissue biomarkers in hepatocellular carcinoma

Autorzy: Venkata Ramana Mallela, Marie Rajtmajerová, Andriy Trailin, Václav Liška, Kari Hemminki, Filip Ambrozkiewicz
Opublikowane w: Non-coding RNA Research, Numer 9, 2024, Strona(/y) 24-32, ISSN 2468-0540
Wydawca: KeAi Communications Co., Ltd.
DOI: 10.1016/j.ncrna.2023.10.010

The Asthma Family Tree: Evaluating Associations Between Childhood, Parental, and Grandparental Asthma in Seven Chinese Cities

Autorzy: Yu Hongyao; Su Fan; Wang Le-Bing; Hemminki Kari Jussi; Dharmage Shyamali C; Bowatte Gayan; Bui Dinh; Qian Zhengmin; Vaughn Michael G; Aaron Hannah E; Xiong Shimin; Shen Xubo; Zhou Yuanzhong; Zhou Peien; Zeng Xiao-Wen; Chen Gongbo; Yang Bo-Yi; Hu Li-Wen; Dong Guang-Hui
Opublikowane w: Frontiers in Pediatrics, Numer 9, 2021, ISSN 2296-2360
Wydawca: Frontiers Media S.A.
DOI: 10.3389/fped.2021.720273

A rare large duplication of MLH1 identified in Lynch syndrome

Autorzy: Abhishek Kumar, Nagarajan Paramasivam, Obul Reddy Bandapalli, Matthias Schlesner, Tianhui Chen, Rolf Sijmons, Dagmara Dymerska, Katarzyna Golebiewska, Magdalena Kuswik, Jan Lubinski, Kari Hemminki, Asta Försti
Opublikowane w: Hereditary Cancer in Clinical Practice, Numer 19, 2021, ISSN 1897-4287
Wydawca: BioMed Central Ltd
DOI: 10.1186/s13053-021-00167-0

Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach

Autorzy: Giulia Brigante, Clara Lazzaretti, Elia Paradiso, Federico Nuzzo, Martina Sitti, Frank Tüttelmann, Gabriele Moretti, Roberto Silvestri, Federica Gemignani, Asta Försti, Kari Hemminki, Rossella Elisei, Cristina Romei, Eric Adriano Zizzi, Marco Agostino Deriu, Manuela Simoni, Stefano Landi, Livio Casarini
Opublikowane w: European Thyroid Journal, Numer 11, 2024, ISSN 2235-0802
Wydawca: Bioscientifica
DOI: 10.1530/etj-22-0058

Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries

Autorzy: Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki, Kari Hemminki
Opublikowane w: Obstetrics and Gynecology International, Numer 2023, 2023, Strona(/y) 1-9, ISSN 1687-9597
Wydawca: John Wiley & Sons Ltd
DOI: 10.1155/2023/6909414

Are population level familial risks and germline genetics meeting each other?

Autorzy: Kari Hemminki, Xinjun Li, Asta Försti, Charis Eng
Opublikowane w: Hereditary Cancer in Clinical Practice, Numer 21, 2023, ISSN 1897-4287
Wydawca: BMC
DOI: 10.1186/s13053-023-00247-3

Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment

Autorzy: Marie Rajtmajerová, Andriy Trailin, Václav Liška, Kari Hemminki, Filip Ambrozkiewicz
Opublikowane w: Cancers, Numer 14, 2024, Strona(/y) 5450, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14215450

Survival in gastric and esophageal cancers in the Nordic countries through a half century

Autorzy: Kari Hemminki, Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki
Opublikowane w: Cancer Medicine, Numer 12, 2024, Strona(/y) 10212-10221, ISSN 2045-7634
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cam4.5748

Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations

Autorzy: Li Xinjun; Sundquist Kristina; Sundquist Jan; Försti Asta; Hemminki Kari Jussi
Opublikowane w: Scientific Reports, Numer 20452322, 2021, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-021-90542-7

Identification of novel genetic loci for risk of multiple myeloma by functional annotation

Autorzy: Angelica Macauda, Klara Briem, Alyssa Clay-Gilmour, Wendy Cozen, Asta Försti, Matteo Giaccherini, Chiara Corradi, Juan Sainz, Yasmeen Niazi, Rob ter Horst, Yang Li, Mihai G. Netea, Ulla Vogel, Kari Hemminki, Susan L. Slager, Judit Varkonyi, Vibeke Andersen, Elzbieta Iskierka-Jazdzewska, Joaquin Mártinez-Lopez, Jan Zaucha, Nicola J. Camp, S. Vincent Rajkumar, Agnieszka Druzd-Sitek, Parveen Bhatti
Opublikowane w: Leukemia, Numer 37, 2023, Strona(/y) 2326-2329, ISSN 0887-6924
Wydawca: Nature Publishing Group
DOI: 10.1038/s41375-023-02022-8

Association of miR-125b, miR-17 and let-7c Dysregulations With Response to Anti-epidermal Growth Factor Receptor Monoclonal Antibodies in Patients With Metastatic Colorectal Cancer

Autorzy: ONDREJ FIALA, ONDREJ SOREJS, PETR HOSEK, VACLAV LISKA, ONDREJ VYCITAL, JAN BRUHA, RADEK KUCERA, ONDREJ TOPOLCAN, JINDRICH FINEK, DIANA MACECKOVA, PAVEL PITULE
Opublikowane w: Cancer Genomics - Proteomics, Numer 17/5, 2020, Strona(/y) 605-613, ISSN 1109-6535
Wydawca: International Institute of Anticancer Research
DOI: 10.21873/cgp.20217

Familial Risks and Proportions Describing Population Landscape of Familial Cancer

Autorzy: Hemminki Kari Jussi; Sundquist Kristina; Sundquist Jan; Foersti Asta; Hemminki Akseli; Li Xinjun
Opublikowane w: Cancers, Numer 20726694, 2021, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13174385

Long-term incidence in hepatocellular carcinoma and intrahepatic bile duct cancer in Denmark, Finland, Norway and Sweden, role of Thorotrast?

Autorzy: Kari Hemminki, Filip Tichanek, Asta Försti, Otto Hemminki, Vaclav Liska, Akseli Hemminki
Opublikowane w: International Journal of Cancer, Numer 10970215, 2022, ISSN 1097-0215
Wydawca: UICC
DOI: 10.1002/ijc.34031

Whole Genome Sequencing Prioritizes CHEK2, EWSR1, and TIAM1 as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer

Autorzy: Srivastava Aayushi; Giangiobbe Sara; Skopelitou Diamanto; Miao Beiping; Paramasivam Nagarajan; Diquigiovanni Chiara; Bonora Elena; Hemminki Kari Jussi; Försti Asta; Bandapalli Obul Reddy
Opublikowane w: Frontiers in Endocrinology, 2021, ISSN 1664-2392
Wydawca: Frontiers Media SA
DOI: 10.3389/fendo.2021.600682

Familial Risks between Pernicious Anemia and Other Autoimmune Diseases in the Population of Sweden

Autorzy: Xinjun Li, Hauke Thomsen, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Opublikowane w: Autoimune Diseases, 2021, ISSN 2090-0422
Wydawca: Hindawi Publishing Corporation
DOI: 10.1155/2021/8815297

Survival trends in hematological malignancies in the Nordic countries through 50 years

Autorzy: Kari Hemminki, Janne Hemminki, Asta Försti, Amit Sud
Opublikowane w: Blood Cancer Journal, Numer 12, 2022, ISSN 2044-5385
Wydawca: Nature Publishing Group
DOI: 10.1038/s41408-022-00728-z

Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer.

Autorzy: Diamanto Skopelitou; Beiping Miao; Aayushi Srivastava; Abhishek Kumar; Abhishek Kumar; Magdalena Kuswick; Dagmara Dymerska; Nagarajan Paramasivam; Matthias Schlesner; Jan Lubinski; Kari Hemminki; Kari Hemminki; Asta Försti; Obul Reddy Bandapalli
Opublikowane w: International Journal of Molecular Sciences, Numer 5, 2021, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22041837

Survival in colon and rectal cancers in Finland and Sweden through 50 years

Autorzy: Hemminki Kari Jussi; Försti Asta; Hemminki Akseli
Opublikowane w: BMJ Open Gastroenterology, Numer 20544774, 2021, ISSN 2054-4774
Wydawca: BMJ Publishing Group Ltd
DOI: 10.1136/bmjgast-2021-000644

Early mortality critically impedes improvements in thyroid cancer survival through a half century

Autorzy: Filip Tichanek, Asta Försti, Vaclv Liska, Otto Hemminki, Anni Koskinen, Akseli Hemminki, Kari Hemminki
Opublikowane w: European Journal of Endocrinology, Numer 189, 2023, Strona(/y) 355-362, ISSN 0804-4643
Wydawca: BioScientifica Ltd.
DOI: 10.1093/ejendo/lvad117

Long-term incidence and survival trends in cancer of the gallbladder and extrahepatic bile ducts in Denmark, Finland, Norway and Sweden with etiological implications related to Thorotrast

Autorzy: Hemminki Kari Jussi; Försti Asta; Hemminki Otto; Liška Václav; Hemminki Akse
Opublikowane w: International Journal of Cancer, Numer 151/2, 2022, ISSN 1097-0215
Wydawca: Union for International Cancer Control (UICC)
DOI: 10.1002/ijc.33980

Epidemiology, genetics and treatment of multiple myeloma and precursor diseases

Autorzy: Hemminki Kari Jussi; Försti Asta; Houlston Richard; Sud Amit
Opublikowane w: International Journal of Cancer, Numer 10970215, 2021, ISSN 1097-0215
Wydawca: UICC
DOI: 10.1002/ijc.33762

Autoimmune diseases as comorbidities for liver, gallbladder, and biliary duct cancers in Sweden

Autorzy: Kari Hemminki, Kristina Sundquist, Jan Sundquist, Asta Försti, Vaclav Liska, Akseli Hemminki, Xinjun Li
Opublikowane w: Cancer, Numer 129, 2023, Strona(/y) 1227-1236, ISSN 0008-543X
Wydawca: John Wiley & Sons Inc.
DOI: 10.1002/cncr.34663

Familial associations for rheumatoid autoimmune diseases

Autorzy: Hauke Thomsen, Xinjun Li, Kristina Sundquist, Jan Sundquist, Asta Försti, Kari Hemminki
Opublikowane w: Rheumatology Advances in Practice, Numer 4/2, 2020, ISSN 2514-1775
Wydawca: Oxford University Press
DOI: 10.1093/rap/rkaa048

Survival in bladder and upper urinary tract cancers in Finland and Sweden through 50 years

Autorzy: Kari Hemminki; Asta Försti; Akseli Hemminki; Börje Ljungberg, Otto Hemminki
Opublikowane w: Plos One, Numer 19326203, 2022, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0261124

Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment

Autorzy: Kari Hemminki; Anna Kanerva; Asta Försti; Akseli Hemminki
Opublikowane w: BMC Cancer, Numer 14712407, 2022, ISSN 1471-2407
Wydawca: BioMed Central
DOI: 10.1186/s12885-022-09582-5

DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations

Autorzy: Niazi Yasmeen; Thomsen Hauke; Smolkova Bozena; Vodičková Ludmila; Vodenková Soňa; Kroupa Michal; Vymetálková Veronika; Kazimirova Alena; Barancokova Magdalena; Volkovova Katarina; Staruchova Marta; Hoffmann Per; Noethen Markus M; Dusinska Maria; Musak Ludovit; Vodička Pavel; Hemminki Kari Jussi; Foersti Asta
Opublikowane w: Frontiers in Genetics, Numer 12, 2021, ISSN 1664-8021
Wydawca: Frontiers Media
DOI: 10.3389/fgene.2021.691947

Cancer Predisposition Genes in Cancer-Free Families

Autorzy: Guoqiao Zheng, Calogerina Catalano, Obul Reddy Bandapalli, Nagarajan Paramasivam, Subhayan Chattopadhyay, Matthias Schlesner, Rolf Sijmons, Akseli Hemminki, Dagmara Dymerska, Jan Lubinski, Kari Hemminki, Asta Försti
Opublikowane w: Cancers, Numer 12/10, 2020, Strona(/y) 2770, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12102770

Critical survival periods in prostate cancer in Sweden explored by conditional survival analysis

Autorzy: Kari Hemminki, Frantisek Zitricky, Kristina Sundquist, Jan Sundquist, Asta Försti, Akseli Hemminki, Otto Hemminki
Opublikowane w: Cancer Medicine, Numer 13, 2024, ISSN 2045-7634
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/cam4.7126

Incidence and survival in laryngeal and lung cancers in Finland and Sweden through a half century

Autorzy: Anni Koskinen,Otto Hemminki,Asta Försti,Kari Hemminki
Opublikowane w: Plos One, Numer 19326203, 2022, ISSN 1932-6203
Wydawca: Public Library of Science
DOI: 10.1371/journal.pone.0268922

Mutational analysis of driver genes defines the colorectal adenoma: in situ carcinoma transition

Autorzy: Jungwirth Jiří; Urbanová Markéta; Boot Arnoud; Hošek Petr; Bendová Petra; Šišková Anna; Švec Jiří; Kment Milan; Tůmová Daniela; Summerová Sandra; Beneš Zdeněk; Büchler Tomáš; Kohout Pavel; Hucl Tomáš; Matěj Radoslav; Vodičková Ludmila; van Wezel Tom; Vodička Pavel; Vymetálková Veronika
Opublikowane w: Scientific Reports, Numer 12/1, 2022, ISSN 2045-2322
Wydawca: Nature Publishing Group
DOI: 10.1038/s41598-022-06498-9

Incidence, Mortality and Survival Trends in Breast Cancers Coincident with Introduction of Mammography in the Nordic Countries

Autorzy: Kari Hemminki, Asta Försti
Opublikowane w: Cancers, Numer 14, 2024, Strona(/y) 5907, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14235907

Survival trends in solid cancers in the Nordic countries through 50 years

Autorzy: Janne Hemminki, Asta Försti, Akseli Hemminki, Kari Hemminki
Opublikowane w: European Journal of Cancer, Numer 175, 2022, Strona(/y) 77-85, ISSN 0959-8049
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.ejca.2022.08.015

Family History of Head and Neck Cancers

Autorzy: Li Xinjun; Koskinen Anni I; Hemminki Otto; Försti Asta; Sundquist Jan; Sundquist Kristina; Hemminki Kari Jussi
Opublikowane w: Cancers, Numer 13/16, 2021, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13164115

Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts

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Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century

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Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers

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A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer

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Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor

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A metric for comparison and visualization of age disparities in cancer survival

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Metformin Use and the Outcome of Metastatic Renal Cell Carcinoma Treated with Sunitinib or Pazopanib

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Conditional survival in breast cancer up to 10 years in the Nordic countries

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Survival in Elderly Ovarian Cancer Remains Challenging in the Nordic Countries

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Octreotide in the treatment of malignant thymoma - Case report

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Large differencies in age-specific survival in multiple myeloma in the nordic countries

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Survival in hematological malignancies in the Nordic countries through a half century with correlation to treatment

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Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis

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Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example

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Genetic and environmental associations of nonspecific chromosomal aberrations

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Major improvement in thyroid cancer survival of elderly patients in the Nordic countries

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Outcomes According to MSKCC Risk Score with Focus on the Intermediate-Risk Group in Metastatic Renal Cell Carcinoma Patients Treated with First-Line Sunitinib: A Retrospective Analysis of 2390 Patients

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Long-term survival trends for primary liver and pancreatic cancers in the Nordic countries

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Mast Cells in the Microenvironment of Hepatocellular Carcinoma Confer Favorable Prognosis: A Retrospective Study using QuPath Image Analysis Software

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Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients

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Incidence, mortality and survival in malignant pleural mesothelioma before and after asbestos in Denmark, Finland, Norway and Sweden

Autorzy: Hemminki Kari Jussi; Forsti Asta; Chen Tianhui; Hemminki Akseli
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Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer

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CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence

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Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016

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Characterization of rare germline variants in familial multiple myeloma

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Conditional Survival in Prostate Cancer in the Nordic Countries Elucidates the Timing of Improvements

Autorzy: Frantisek Zitricky, Asta Försti, Akseli Hemminki, Otto Hemminki, Kari Hemminki
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Activated Hepatic Stellate Cells in Hepatocellular Carcinoma: Their Role as a Potential Target for Future Therapies

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Survival in melanoma in the nordic countries into the era of targeted and immunological therapies

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Survival improvements in esophageal and gastric cancers in the Nordic countries favor younger patients

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Enhanced Anti-lymphoma Activity of CAR19-iNKT Cells Underpinned by Dual CD19 and CD1d Targeting

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Prognostic role of macrophages and mast cells in the microenvironment of hepatocellular carcinoma after resection

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Familial risks between giant cell arteritis and Takayasu arteritis and other autoimmune diseases in the population of Sweden

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Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients’ outcomes

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DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population

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Search for AL amyloidosis risk factors using Mendelian randomization

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Long-Term Periodic and Conditional Survival Trends in Prostate, Testicular, and Penile Cancers in the Nordic Countries, Marking Timing of Improvements

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Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor

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Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden

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Long‐term survival trends in solid cancers in the Nordic countries marking timing of improvements

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Burden of malignant mesothelioma in China during 1990–2019 and the projections through 2029

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Theranostics Nanomedicine Applications for Colorectal Cancer and Metastasis: Recent Advances

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Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers

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Familial Risks for Liver, Gallbladder and Bile Duct Cancers and for Their Risk Factors in Sweden, a Low-Incidence Country

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Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers

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Germline Variants of CYBA and TRPM4 Predispose to Familial Colorectal Cancer

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Familial associations for Addison's disease and between Addison's disease and other autoimmune diseases

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Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization

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Age-specific survival in acute myeloid leukemia in the Nordic countries through a half century

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Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases

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Types of second primary cancer influence overall survival in cutaneous melanoma

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Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden

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Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer

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Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers

Autorzy: Kari Hemminki, Kristina Sundquist, Jan Sundquist, Asta Försti, Vaclav Liska, Akseli Hemminki, Xinjun Li
Opublikowane w: Cancers, Numer 15, 2023, Strona(/y) 3092, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15123092

Survival in Kidney and Bladder Cancers in Four Nordic Countries through a Half Century

Autorzy: Filip Tichanek, Asta Försti, Akseli Hemminki, Otto Hemminki, Kari Hemminki
Opublikowane w: Cancers, Numer 15, 2023, Strona(/y) 2782, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15102782

T- and B-Cells in the Inner Invasive Margin of Hepatocellular Carcinoma after Resection Associate with Favorable Prognosis

Autorzy: Trailin Andriy; Červenková Lenka; Ambrożkiewicz Filip; Sobhe Abdelhamid Mahmoud Esraa; Kasi Phanindra Babu; Pálek Richard; Hošek Petr; Třeška Vladislav; Daum Ondřej; Tonar Zbyněk; Liška Václav; Hemminki Kari Jussi
Opublikowane w: Cancers, Numer 20726694, 2022, ISSN 2072-6694
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14030604

Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years

Autorzy: Filip Tichanek, Asta Försti, Otto Hemminki, Akseli Hemminki, Kari Hemminki
Opublikowane w: Cancer Epidemiology, Numer 92, 2024, Strona(/y) 102449, ISSN 1877-7821
Wydawca: Elsevier BV
DOI: 10.1016/j.canep.2023.102449