TRANSTEM: ERA Chair in Translational Stem Cell Biology

Deliverables

Websites, patent fillings, videos etc. (1)

Project Website

D7.1. will report the creation of Project Website

Documents, reports (3)

Published Job Position Advertisement

D1.3. will report the published Job Position Advertisement

Paper: “Stem Cell Research Department: Vision and Strategy”

D15 will report the publishment of the paper Stem Cell Research Department Vision and Strategy

Newly created department of Stem Cell Biology in RI-MUV

D1.1. will report the creation of the new department of Stem Cell Biology in RI-MUV

Open Research Data Pilot (1)

DMP Submission

D8.8. DMP Submission will report Data Management Plan

Publications

Peer reviewed articles (11)

<scp>GDF11</scp> inhibits adipogenesis and improves mature adipocytes metabolic function via <scp>WNT</scp> /β‐catenin and <scp>ALK5</scp> / <scp>SMAD2</scp> /3 pathways

Author(s): Jan Frohlich; Kristina Kovacovicova; Marco Raffaele; Tereza Virglova; Eliska Cizkova; Jan Kucera; Julie Bienertova‐Vasku; Martin Wabitsch; Marion Peyrou; Francesca Bonomini; Rita Rezzani; George N. Chaldakov; Anton B. Tonchev; Michelino Di Rosa; Nicolas Blavet; Vaclav Hejret; Manlio Vinciguerra
Published in: Crossref, 13652184, 2022, ISSN 1365-2184
Publisher: Cell Proliferation
DOI: 10.1111/cpr.13310

Mild exacerbation of obesity- and age-dependent liver disease progression by senolytic cocktail dasatinib + quercetin

Author(s): Marco Raffaele; Kristina Kovacovicova; Jan Frohlich; Oriana Lo Re; Sebastiano Giallongo; Jude A. Oben; Martin Faldyna; Lenka Leva; Antonino Giulio Giannone; Daniela Cabibi; Manlio Vinciguerra; Manlio Vinciguerra
Published in: Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-9 (2021), 1478811X, 2021, ISSN 1478-811X
Publisher: BioMed Central
DOI: 10.1186/s12964-021-00731-0

Systemic depletion of histone macroH2A1.1 boosts hippocampal synaptic plasticity and social behavior in mice.

Author(s): Valentina Chiodi; Maria Rosaria Domenici; Tommaso Biagini; Roberta De Simone; Anna Maria Tartaglione; Michelino Di Rosa; Oriana Lo Re; Tommaso Mazza; Vincenzo Micale; Vincenzo Micale; Manlio Vinciguerra; Manlio Vinciguerra
Published in: The FASEB Journal, 08926638, 2021, ISSN 0892-6638
Publisher: Federation of American Societies for Experimental Biology
DOI: 10.1096/fj.202100569r

Histone Variant macroH2A1.1 Enhances Nonhomologous End Joining-dependent DNA Double-strand-break Repair and Reprogramming Efficiency of Human iPSCs

Author(s): Sebastiano Giallongo, Daniela Řeháková, Tommaso Biagini, Oriana Lo Re, Priyanka Raina, Gabriela Lochmanová, Zbyněk Zdráhal, Igor Resnick, Pille Pata, Illar Pata, Martin Mistrík, João Pedro de Magalhães, Tommaso Mazza, Irena Koutná, Manlio Vinciguerra
Published in: Stem Cells, 10665099, 2022, ISSN 1066-5099
Publisher: AlphaMed Press Inc
DOI: 10.1093/stmcls/sxab004

Cardio- and Neurometabolic Adipobiology: Consequences and Implications for Therapy

Author(s): Frohlich J, Chaldakov GN, Vinciguerra M.
Published in: International Journal of Molecular Sciences, 14220067, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084137

Reduced neuroinflammation and enhanced neurogenesis following chronic agomelatine treatment in rats undergoing chronic constant light

Author(s): Atanasova D, Lazarov N, Stoyanov DS, Spassov RH, Tonchev AB, Tchekalarova J
Published in: Neuropharmacology, 00283908, 2021, ISSN 0028-3908
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neuropharm.2021.108706

Expression of Transcription Factor ZBTB20 in the Adult Primate Neurogenic Niche under Physiological Conditions or after Ischemia

Author(s): Dimo S. Stoyanov, Martin N. Ivanov, Tetsumori Yamashima, Anton B. Tonchev
Published in: Genes, 20734425, 2022, ISSN 2073-4425
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/genes13091559

Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects.

Author(s): Marco Raffaele; Kristina Kovacovicova; Tommaso Biagini; Oriana Lo Re; Jan Frohlich; Sebastiano Giallongo; James D. Nhan; Antonino Giulio Giannone; Daniela Cabibi; Martin Ivanov; Anton B. Tonchev; Martin Mistrik; Matthew Lacey; Petr Dzubak; Sona Gurska; Marian Hajduch; Jiri Bartek; Jiri Bartek; Tommaso Mazza; Vincenzo Micale; Sean P. Curran; Manlio Vinciguerra
Published in: GeroScience, 25092723, 2021, ISSN 2509-2723
Publisher: Springer
DOI: 10.1007/s11357-021-00487-y

Ghrelin Regulates Expression of the Transcription Factor Pax6 in Hypoxic Brain Progenitor Cells and Neurons

Author(s): Irina I. Stoyanova, Andrii Klymenko, Jeannette Willms, Thorsten R. Doeppner, Anton B. Tonchev, David Lutz
Published in: Cells, 20734409, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11050782

Transcriptome Response and Spatial Pattern of Gene Expression in the Primate Subventricular Zone Neurogenic Niche After Cerebral Ischemia

Author(s): Monika C Chongtham, Haifang Wang, Christina Thaller, Nai-Hua Hsiao, Ivan H Vachkov, Stoyan P Pavlov, Lorenz H Williamson, Tetsumori Yamashima, Anastassia Stoykova, Jun Yan, Gregor Eichele, Anton B Tonchev
Published in: Frontiers in Cell and Developmental Biology, 2020, ISSN 2296-634X
Publisher: Frontiers Media S.A.
DOI: 10.3389/fcell.2020.584314

Phosphorylation within Intrinsic Disordered Region Discriminates Histone Variant macroH2A1 Splicing Isoforms—macroH2A1.1 and macroH2A1.2

Author(s): Sebastiano Giallongo, Oriana Lo Re, Gabriela Lochmanová, Luca Parca, Francesco Petrizzelli, Zbyněk Zdráhal, Tommaso Mazza, Manlio Vinciguerra
Published in: Biology, 20797737, 2021, ISSN 2079-7737
Publisher: MDPI
DOI: 10.3390/biology10070659