Description du projet
Stimuler la recherche en biologie des infections en Estonie
La découverte de la pénicilline en 1928 a marqué le début de l’ère des antibiotiques, révolutionnant le traitement des maladies infectieuses et réduisant considérablement le nombre de décès. Au fil des ans, les infections, en particulier les infections latentes, peuvent se réactiver sur une période de plusieurs mois, voire de plusieurs années. Ce phénomène entraîne toujours des taux élevés de morbidité et de mortalité dans le monde. Le projet MIBEst, financé par l’UE, entend approfondir les connaissances scientifiques dans le domaine de la biologie des infections en ciblant notamment les avancées dans les modèles d’infections latentes. Le projet renforcera la capacité de recherche de l’Institut de technologie de l’Université de Tartu, en Estonie, dans les infections latentes et chroniques en tissant des liens avec les plus grandes universités de Suède et de Suisse.
Objectif
Infectious diseases have been the leading cause of death for many centuries. The development of vaccination and antibiotic treatments combined with improved hygiene has decreased the number of deaths, but the mortality and morbidity associated with infections remain considerable, requiring constant societal awareness and scientific research. An increasing concern are the latent and chronic infections that are often refractory to treatments. As the frequency of latent infections increases with age, it is a major concern for aging societies. The great diversity of the infectious agents, and the multidisciplinary nature of the infectious biology research demand a convergence of various competencies: microbiology, cell biology, animal infection models, immunology etc, emphasizing the need for collaboration between research centres. Especially important are joint activities for smaller countries, e.g. Estonia, where establishment of full-scale stand-alone programs is not economically feasible. Despite the strong positions in basic molecular biology, virology and microbiology, Estonia often fails to capitalize on the excellence in basic research by transitioning to the development of therapeutics targeting medically relevant processes. The main objective of the MIBEst project is to strengthen the research capacity on latent and chronic infections of Institute of Technology at University of Tartu by creating long-lasting links with internationally-leading research institutions: Molecular Infection Medicine Sweden at Umeå University, Sweden, and Basel Biozentrum, University of Basel, Switzerland. As an outcome of MIBEst, Estonian scientists will have new knowledge in infection biology with particular focus on advancement in models for latent infections and high throughput screening for promising candidates for antiinfective compounds. Altogether, it enables development of new anti-infection strategies that will have major impact at the national, European and global scale.
Champ scientifique
Mots‑clés
Programme(s)
- H2020-EU.4.b. - Twinning of research institutions Main Programme
Thème(s)
Régime de financement
CSA - Coordination and support actionCoordinateur
51005 Tartu
Estonie