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Integration of knowledge and biobank resources in comprehensive translational approach for personalized prevention and treatment of metabolic disorders

Project description

Mentoring Latvia's medical excellence from benchside to bedside

Mapping the entire human genome in 2003 spawned a wealth of new technologies for linking normal and pathologic conditions to specific genes, DNA, RNA, proteins, carbohydrates, lipids, metabolites and more. Biobanks were created to safely store biological samples. To process the huge volume of newly available data, novel methods in cellular and systems biology, bioinformatics and computational modelling have grown exponentially. EU-funded scientists have joined forces under the INTEGROMED project to enhance Latvia's excellence in utilisation of these resources in close partnership with the national health care system. Together, they hope to foster development of personalised clinical care, scientific collaboration and entrepreneurship.

Objective

INTEGROMED is aiming to provide LBMC with the opportunity to integrate the experience of research excellence institutions and existing resources by creating a research and innovation network with three internationally leading organizations in the translational medicine area – University of Dundee, Lund University, and Weizmann Institute of Science. The strategy of INTEGROMED is to increase excellence and develop sustainable approach targeting virtually all aspects of translational medicine including the optimal use of clinical and biobank resources, integration of different omics in systemic workflow, reaching development of bedside applications and fostering entrepreneurism. Project has a strong focus on study of metabolic disorders including type 2 diabetes, however the training, mentoring and stuff exchange activities as well as practical outcomes will be available for other fields including researchers, clinicians and other stakeholders in Latvia, promoting the implementation of the developed strategies at larger scale.
The result of project will be accomplished by following three main objectives. (1) To improve and optimize the use of resources provided by large biobanks and prospective cohorts in combination with national health care system, improve knowledge in establishment of clinical studies for development of precision medicine approaches. (2) To strengthen collaboration-based training of specialists in areas of multi-omics approaches, bioinformatics, and modelling to increase excellence in implementing cutting edge multi omics technologies in such areas as genomics, methylation and expression profile, microbiome and metabolome analysis. (3) To elaborate a long-term strategy and sustainability plan involving all relevant stakeholders, ensure development and training in clinical applications and entrepreneurial skills to build an innovation ecosystem around LBMC.

Call for proposal

H2020-WIDESPREAD-2018-2020

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Sub call

H2020-WIDESPREAD-2018-03

Coordinator

LATVIJAS BIOMEDICINAS PETIJUMU UN STUDIJU CENTRS
Net EU contribution
€ 350 000,00
Address
RATSUPITES IELA 1
1067 Riga
Latvia

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Region
Latvija Latvija Rīga
Activity type
Research Organisations
Links
Total cost
€ 350 000,00

Participants (3)