Molecular Machines Functioning in Cells

Project Information

BIOMOLMACS

Grant agreement ID: 859416

DOI

10.3030/859416

Project closed

EC signature date 11 September 2019

Start date 1 January 2020

End date 30 June 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 4 107 786,48

EU contribution

€ 4 107 786,48

Coordinated by

UNIVERSITY OF WARWICK
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (7)

Publication of results in peer-reviewed journals.
Project handbook for ESRs, academics and industrial partners

Project handbook for ESRs academics and industrial partners

Outreach activities and public engagement.
Presentation of results at international conferences.
BIOMOLMACS communication report
Report on training implementation and quality
Training quality assessment checklist

Websites, patent fillings, videos etc. (3)

First online version of the network public website
Project website and online accounts (Twitter, Facebook) to be setup

Project website and online accounts Twitter Facebook to be setup

Advertisement of ESRs on international websites including EurAxess

Open Research Data Pilot (1)

Data management plan

Publications

Peer reviewed articles (30)

Designing P-type bi-stable overcrowded alkene-based chiroptical photoswitches

Author(s): Jinyu Sheng, Wojciech Danowski, Stefano Crespi, Ainoa Guinart, Xiaobing Chen, Cosima Stähler, Ben L. Feringa
Published in: Chemical Science, Issue 14, 2024, Page(s) 4328-4336, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2sc05903g

Effect of temperature on glycopolymer and Con A binding properties

Author(s): Jichuan Chen, Roberto Terracciano, Jonas Becker, Gokhan Yilmaz, C. Remzi Becer
Published in: European Polymer Journal, Issue 211, 2024, Page(s) 113006, ISSN 0014-3057
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2024.113006

Enzymatically-induced dynamic assemblies from surface functional stomatocyte nanoreactors

Author(s): Alexander D. Fusi, Yudong Li, Marrit M. E. Tholen, Marlo Cieraad, Lorenzo Albertazzi, Tania Patiño Padial, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Published in: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4tb01320d

Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques

Author(s): Camilla Pegoraro, Inés Domingo-Ortí, Inmaculada Conejos-Sánchez, María J. Vicent
Published in: Advanced Drug Delivery Reviews, Issue 207, 2024, Page(s) 115195, ISSN 0169-409X
Publisher: Elsevier BV
DOI: 10.1016/j.addr.2024.115195

Competitive protein recruitment in artificial cells

Author(s): Thijs W. van Veldhuisen, Madelief A. M. Verwiel, Sebastian Novosedlik, Luc Brunsveld, Jan C. M. van Hest
Published in: Communications Chemistry, Issue 7, 2024, ISSN 2399-3669
Publisher: Nature
DOI: 10.1038/s42004-024-01229-9

Design Features to Accelerate the Higher-Order Assembly of DNA Origami on Membranes

Author(s): Qutbuddin, Yusuf; Krohn, Jan-Hagen; Brüggenthies, Gereon A.; Stein, Johannes; Gavrilovic, Svetozar; Stehr, Florian; Schwille, Petra
Published in: The Journal of Physical Chemistry B, Issue 125, 48, 2021, Page(s) 13181–13191, ISSN 1520-6106
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.1c07694

On the Right “Track” to Artificial Assemblers

Author(s): Romain Costil, Ainoa Guinart, Ben L. Feringa
Published in: Chem, Issue 6, 2021, Page(s) 2868-2870, ISSN 2451-9294
Publisher: Cell
DOI: 10.1016/j.chempr.2020.10.016

Step-Growth Glycopolymers with a Defined Tacticity for Selective Carbohydrate–Lectin Recognition

Author(s): Jonas Becker, Roberto Terracciano, Gokhan Yilmaz, Richard Napier, C. Remzi Becer
Published in: Biomacromolecules, Issue 24, 2023, Page(s) 1924-1933, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.3c00133

Hierarchy of Complex Glycomacromolecules: From Controlled Topologies to Biomedical Applications

Author(s): Tieshuai Zhao, Roberto Terracciano, Jonas Becker, Alessandra Monaco, Gokhan Yilmaz, C. Remzi Becer
Published in: Biomacromolecules, Issue 23, 2023, Page(s) 543-575, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.1c01294

Achieving Control in Micro‐/Nanomotor Mobility

Author(s): Alexander D. Fusi, Yudong Li, A. Llopis‐Lorente, Tania Patiño, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Published in: Angewandte Chemie International Edition, Issue 62, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202214754

Inducing Lipid Domains in Membranes by Self‐Assembly of DNA Origami

Author(s): Nishu Kanwa, Svetozar Gavrilovic, Gereon A. Brüggenthies, Yusuf Qutbuddin, Petra Schwille
Published in: Advanced Materials Interfaces, Issue 10, 2023, ISSN 2196-7350
Publisher: Wiley
DOI: 10.1002/admi.202202500

Highly Efficient Oxindole‐Based Molecular Photoswitches

Author(s): Daniel Doellerer, Daisy R. S. Pooler, Ainoa Guinart, Stefano Crespi, Ben L. Feringa
Published in: Chemistry – A European Journal, Issue 29, 2024, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202301634

Multifunctional Polypeptide-Based Nanoconjugates for Targeted Mitochondrial Delivery and Nonviral Gene Therapy

Author(s): Camilla Pegoraro, Esther Masiá Sanchis, Snežana Đorđević, Irene Dolz-Pérez, Cristián Huck-Iriart, Lidia Herrera, Sergio Esteban-Pérez, Inmaculada Conejos-Sanchez, María J. Vicent
Published in: Chemistry of Materials, Issue 37, 2025, Page(s) 1457-1467, ISSN 0897-4756
Publisher: American Chemical Society
DOI: 10.1021/acs.chemmater.4c02742

Synthetic molecular motor activates drug delivery from polymersomes

Author(s): Ainoa Guinart, Maria Korpidou, Daniel Doellerer, Gianni Pacella, Marc C. A. Stuart, Ionel Adrian Dinu, Giuseppe Portale, Cornelia Palivan, Ben L. Feringa
Published in: Proceedings of the National Academy of Sciences, Issue 120, 2023, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2301279120

Poly(2-oxazoline)-Based Thermoresponsive Stomatocytes

Author(s): Roberto Terracciano, Yuechi Liu, Zivani Varanaraja, Magdalena Godzina, Gokhan Yilmaz, Jan C. M. van Hest, C. Remzi Becer
Published in: Biomacromolecules, 2024, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.4c00726

Light‐Activated Synthetic Rotary Motors in Lipid Membranes Induce Shape Changes Through Membrane Expansion

Author(s): Yusuf Qutbuddin, Ainoa Guinart, Svetozar Gavrilović, Kareem Al Nahas, Ben L. Feringa, Petra Schwille
Published in: Advanced Materials, Issue 36, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202311176

Degradable thioester core-crosslinked star-shaped polymers

Author(s): Matthew Laurel, Daniel MacKinnon, Jonas Becker, Roberto Terracciano, Ben Drain, Hannes A. Houck, C. Remzi Becer
Published in: Polymer Chemistry, Issue 13, 2024, Page(s) 5579-5589, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2py00901c

Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery

Author(s): Graham Hayes, Beatriz Dias-Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Published in: Biomacromolecules, Issue 24, 2023, Page(s) 5142-5151, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.3c00683

A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake

Author(s): Camilla Pegoraro, Ainoa Guinart, Esther Masiá Sanchis, Daniel Doellerer, Marc C. A. Stuart, Inmaculada Conejos-Sánchez, Ben L. Feringa, María J. Vicent
Published in: Journal of Materials Chemistry B, Issue 13, 2025, Page(s) 2658-2665, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4tb02434f

Inverting glucuronidation of hymecromone <i>in situ</i> by catalytic nanocompartments

Author(s): Maria Korpidou, Viviana Maffeis, Ionel Adrian Dinu, Cora-Ann Schoenenberger, Wolfgang P. Meier, Cornelia G. Palivan
Published in: Journal of Materials Chemistry B, Issue 10, 2024, Page(s) 3916-3926, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2tb00243d

Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles

Author(s): Clémence Schvartzman, Emmanuel Ibarboure, Anouk Martin, Elisabeth Garanger, Angela Mutschler, Sébastien Lecommandoux
Published in: Biomacromolecules, Issue 25, 2024, Page(s) 4087-4094, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.4c00200

Control of Enzyme Reactivity in Response to Osmotic Pressure Modulation Mimicking Dynamic Assembly of Intracellular Organelles

Author(s): Clémence Schvartzman, Hang Zhao, Emmanuel Ibarboure, Vusala Ibrahimova, Elisabeth Garanger, Sébastien Lecommandoux
Published in: Advanced Materials, Issue 35, 2024, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202301856

Utilization of Anthracene-Functionalized Poly(2-oxazolines) as a Dispersant of Carbon Black in Water and Dodecane

Author(s): Zivani Varanaraja, Roberto Terracciano, Nathan Hollingsworth, Ross Green, James Beament, C. Remzi Becer
Published in: Macromolecules, Issue 57, 2024, Page(s) 5769-5779, ISSN 0024-9297
Publisher: American Chemical Society
DOI: 10.1021/acs.macromol.4c00843

Self-Assembly Behavior of Amphiphilic Poly(2-ethyl-2-oxazoline)-<i>b</i>-poly(2-isostearyl-2-oxazoline) Block Copolymers

Author(s): James Lefley, Roberto Terracciano, Zivani Varanaraja, James Beament, C. Remzi Becer
Published in: Macromolecules, Issue 57, 2024, Page(s) 5881-5891, ISSN 0024-9297
Publisher: American Chemical Society
DOI: 10.1021/acs.macromol.4c00833

Degradable glycopolymers for saRNA transfection

Author(s): Alessandra Monaco, Beatriz Dias Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Published in: Polymer Chemistry, Issue 14, 2024, Page(s) 2750-2761, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3py00260h

Two-photon absorption of oxindole-based push–pull molecular motors

Author(s): Ainoa Guinart, Daniel Doellerer, Daisy R.S. Pooler, John Y. de Boer, Sandra Doria, Laura Bussotti, Mariangela Di Donato, Ben L. Feringa
Published in: Journal of Photochemistry and Photobiology A: Chemistry, Issue 453, 2024, Page(s) 115649, ISSN 1010-6030
Publisher: Elsevier BV
DOI: 10.1016/j.jphotochem.2024.115649

Current Perspectives on Synthetic Compartments for Biomedical Applications

Author(s): Lukas Heuberger, Maria Korpidou, Olivia M. Eggenberger, Myrto Kyropoulou, Cornelia G. Palivan
Published in: International Journal of Molecular Sciences, Issue 23, 2024, Page(s) 5718, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105718

Complex Coacervate Materials as Artificial Cells

Author(s): Alexander B. Cook, Sebastian Novosedlik, Jan C. M. van Hest
Published in: Accounts of Materials Research, Issue 4, 2023, Page(s) 287-298, ISSN 2643-6728
Publisher: ACS
DOI: 10.1021/accountsmr.2c00239

Glycooligomer-Functionalized Catalytic Nanocompartments Co-Loaded with Enzymes Support Parallel Reactions and Promote Cell Internalization

Author(s): Maria Korpidou, Jonas Becker, Shabnam Tarvirdipour, Ionel Adrian Dinu, C. Remzi Becer, Cornelia G. Palivan
Published in: Biomacromolecules, Issue 25, 2024, Page(s) 4492-4509, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.4c00526

Polyproline‐Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism

Author(s): Camilla Pegoraro, Ekaterina Karpova, Yusuf Qutbuddin, Esther Masiá Sanchis, Pavels Dimitrijevs, Cristián Huck‐Iriart, Svetozar Gavrilović, Pavel Arsenyan, Petra Schwille, Carles Felip‐León, Aroa Duro‐Castano, Inmaculada Conejos‐Sanchez, María J. Vicent
Published in: Advanced Materials, Issue 37, 2025, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202411595