Molecular Machines Functioning in Cells

Informazioni relative al progetto

BIOMOLMACS

ID dell’accordo di sovvenzione: 859416

DOI

10.3030/859416

Progetto chiuso

Data della firma CE 11 Settembre 2019

Data di avvio 1 Gennaio 2020

Data di completamento 30 Giugno 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 107 786,48

Contributo UE

€ 4 107 786,48

Coordinato da

UNIVERSITY OF WARWICK
United Kingdom

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Documents, reports (7)

Publication of results in peer-reviewed journals.
Project handbook for ESRs, academics and industrial partners

Project handbook for ESRs academics and industrial partners

Outreach activities and public engagement.
Presentation of results at international conferences.
BIOMOLMACS communication report
Report on training implementation and quality
Training quality assessment checklist

Websites, patent fillings, videos etc. (3)

First online version of the network public website
Project website and online accounts (Twitter, Facebook) to be setup

Project website and online accounts Twitter Facebook to be setup

Advertisement of ESRs on international websites including EurAxess

Open Research Data Pilot (1)

Data management plan

Pubblicazioni

Peer reviewed articles (30)

Designing P-type bi-stable overcrowded alkene-based chiroptical photoswitches

Autori: Jinyu Sheng, Wojciech Danowski, Stefano Crespi, Ainoa Guinart, Xiaobing Chen, Cosima Stähler, Ben L. Feringa
Pubblicato in: Chemical Science, Numero 14, 2024, Pagina/e 4328-4336, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d2sc05903g

Effect of temperature on glycopolymer and Con A binding properties

Autori: Jichuan Chen, Roberto Terracciano, Jonas Becker, Gokhan Yilmaz, C. Remzi Becer
Pubblicato in: European Polymer Journal, Numero 211, 2024, Pagina/e 113006, ISSN 0014-3057
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2024.113006

Enzymatically-induced dynamic assemblies from surface functional stomatocyte nanoreactors

Autori: Alexander D. Fusi, Yudong Li, Marrit M. E. Tholen, Marlo Cieraad, Lorenzo Albertazzi, Tania Patiño Padial, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Pubblicato in: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d4tb01320d

Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques

Autori: Camilla Pegoraro, Inés Domingo-Ortí, Inmaculada Conejos-Sánchez, María J. Vicent
Pubblicato in: Advanced Drug Delivery Reviews, Numero 207, 2024, Pagina/e 115195, ISSN 0169-409X
Editore: Elsevier BV
DOI: 10.1016/j.addr.2024.115195

Competitive protein recruitment in artificial cells

Autori: Thijs W. van Veldhuisen, Madelief A. M. Verwiel, Sebastian Novosedlik, Luc Brunsveld, Jan C. M. van Hest
Pubblicato in: Communications Chemistry, Numero 7, 2024, ISSN 2399-3669
Editore: Nature
DOI: 10.1038/s42004-024-01229-9

Design Features to Accelerate the Higher-Order Assembly of DNA Origami on Membranes

Autori: Qutbuddin, Yusuf; Krohn, Jan-Hagen; Brüggenthies, Gereon A.; Stein, Johannes; Gavrilovic, Svetozar; Stehr, Florian; Schwille, Petra
Pubblicato in: The Journal of Physical Chemistry B, Numero 125, 48, 2021, Pagina/e 13181–13191, ISSN 1520-6106
Editore: American Chemical Society
DOI: 10.1021/acs.jpcb.1c07694

On the Right “Track” to Artificial Assemblers

Autori: Romain Costil, Ainoa Guinart, Ben L. Feringa
Pubblicato in: Chem, Numero 6, 2021, Pagina/e 2868-2870, ISSN 2451-9294
Editore: Cell
DOI: 10.1016/j.chempr.2020.10.016

Step-Growth Glycopolymers with a Defined Tacticity for Selective Carbohydrate–Lectin Recognition

Autori: Jonas Becker, Roberto Terracciano, Gokhan Yilmaz, Richard Napier, C. Remzi Becer
Pubblicato in: Biomacromolecules, Numero 24, 2023, Pagina/e 1924-1933, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.3c00133

Hierarchy of Complex Glycomacromolecules: From Controlled Topologies to Biomedical Applications

Autori: Tieshuai Zhao, Roberto Terracciano, Jonas Becker, Alessandra Monaco, Gokhan Yilmaz, C. Remzi Becer
Pubblicato in: Biomacromolecules, Numero 23, 2023, Pagina/e 543-575, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.1c01294

Achieving Control in Micro‐/Nanomotor Mobility

Autori: Alexander D. Fusi, Yudong Li, A. Llopis‐Lorente, Tania Patiño, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Pubblicato in: Angewandte Chemie International Edition, Numero 62, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202214754

Inducing Lipid Domains in Membranes by Self‐Assembly of DNA Origami

Autori: Nishu Kanwa, Svetozar Gavrilovic, Gereon A. Brüggenthies, Yusuf Qutbuddin, Petra Schwille
Pubblicato in: Advanced Materials Interfaces, Numero 10, 2023, ISSN 2196-7350
Editore: Wiley
DOI: 10.1002/admi.202202500

Highly Efficient Oxindole‐Based Molecular Photoswitches

Autori: Daniel Doellerer, Daisy R. S. Pooler, Ainoa Guinart, Stefano Crespi, Ben L. Feringa
Pubblicato in: Chemistry – A European Journal, Numero 29, 2024, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202301634

Multifunctional Polypeptide-Based Nanoconjugates for Targeted Mitochondrial Delivery and Nonviral Gene Therapy

Autori: Camilla Pegoraro, Esther Masiá Sanchis, Snežana Đorđević, Irene Dolz-Pérez, Cristián Huck-Iriart, Lidia Herrera, Sergio Esteban-Pérez, Inmaculada Conejos-Sanchez, María J. Vicent
Pubblicato in: Chemistry of Materials, Numero 37, 2025, Pagina/e 1457-1467, ISSN 0897-4756
Editore: American Chemical Society
DOI: 10.1021/acs.chemmater.4c02742

Synthetic molecular motor activates drug delivery from polymersomes

Autori: Ainoa Guinart, Maria Korpidou, Daniel Doellerer, Gianni Pacella, Marc C. A. Stuart, Ionel Adrian Dinu, Giuseppe Portale, Cornelia Palivan, Ben L. Feringa
Pubblicato in: Proceedings of the National Academy of Sciences, Numero 120, 2023, ISSN 0027-8424
Editore: National Academy of Sciences
DOI: 10.1073/pnas.2301279120

Poly(2-oxazoline)-Based Thermoresponsive Stomatocytes

Autori: Roberto Terracciano, Yuechi Liu, Zivani Varanaraja, Magdalena Godzina, Gokhan Yilmaz, Jan C. M. van Hest, C. Remzi Becer
Pubblicato in: Biomacromolecules, 2024, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.4c00726

Light‐Activated Synthetic Rotary Motors in Lipid Membranes Induce Shape Changes Through Membrane Expansion

Autori: Yusuf Qutbuddin, Ainoa Guinart, Svetozar Gavrilović, Kareem Al Nahas, Ben L. Feringa, Petra Schwille
Pubblicato in: Advanced Materials, Numero 36, 2024, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202311176

Degradable thioester core-crosslinked star-shaped polymers

Autori: Matthew Laurel, Daniel MacKinnon, Jonas Becker, Roberto Terracciano, Ben Drain, Hannes A. Houck, C. Remzi Becer
Pubblicato in: Polymer Chemistry, Numero 13, 2024, Pagina/e 5579-5589, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/d2py00901c

Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery

Autori: Graham Hayes, Beatriz Dias-Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Pubblicato in: Biomacromolecules, Numero 24, 2023, Pagina/e 5142-5151, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.3c00683

A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake

Autori: Camilla Pegoraro, Ainoa Guinart, Esther Masiá Sanchis, Daniel Doellerer, Marc C. A. Stuart, Inmaculada Conejos-Sánchez, Ben L. Feringa, María J. Vicent
Pubblicato in: Journal of Materials Chemistry B, Numero 13, 2025, Pagina/e 2658-2665, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d4tb02434f

Inverting glucuronidation of hymecromone <i>in situ</i> by catalytic nanocompartments

Autori: Maria Korpidou, Viviana Maffeis, Ionel Adrian Dinu, Cora-Ann Schoenenberger, Wolfgang P. Meier, Cornelia G. Palivan
Pubblicato in: Journal of Materials Chemistry B, Numero 10, 2024, Pagina/e 3916-3926, ISSN 2050-7518
Editore: Royal Society of Chemistry
DOI: 10.1039/d2tb00243d

Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles

Autori: Clémence Schvartzman, Emmanuel Ibarboure, Anouk Martin, Elisabeth Garanger, Angela Mutschler, Sébastien Lecommandoux
Pubblicato in: Biomacromolecules, Numero 25, 2024, Pagina/e 4087-4094, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.4c00200

Control of Enzyme Reactivity in Response to Osmotic Pressure Modulation Mimicking Dynamic Assembly of Intracellular Organelles

Autori: Clémence Schvartzman, Hang Zhao, Emmanuel Ibarboure, Vusala Ibrahimova, Elisabeth Garanger, Sébastien Lecommandoux
Pubblicato in: Advanced Materials, Numero 35, 2024, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202301856

Utilization of Anthracene-Functionalized Poly(2-oxazolines) as a Dispersant of Carbon Black in Water and Dodecane

Autori: Zivani Varanaraja, Roberto Terracciano, Nathan Hollingsworth, Ross Green, James Beament, C. Remzi Becer
Pubblicato in: Macromolecules, Numero 57, 2024, Pagina/e 5769-5779, ISSN 0024-9297
Editore: American Chemical Society
DOI: 10.1021/acs.macromol.4c00843

Self-Assembly Behavior of Amphiphilic Poly(2-ethyl-2-oxazoline)-<i>b</i>-poly(2-isostearyl-2-oxazoline) Block Copolymers

Autori: James Lefley, Roberto Terracciano, Zivani Varanaraja, James Beament, C. Remzi Becer
Pubblicato in: Macromolecules, Numero 57, 2024, Pagina/e 5881-5891, ISSN 0024-9297
Editore: American Chemical Society
DOI: 10.1021/acs.macromol.4c00833

Degradable glycopolymers for saRNA transfection

Autori: Alessandra Monaco, Beatriz Dias Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Pubblicato in: Polymer Chemistry, Numero 14, 2024, Pagina/e 2750-2761, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/d3py00260h

Two-photon absorption of oxindole-based push–pull molecular motors

Autori: Ainoa Guinart, Daniel Doellerer, Daisy R.S. Pooler, John Y. de Boer, Sandra Doria, Laura Bussotti, Mariangela Di Donato, Ben L. Feringa
Pubblicato in: Journal of Photochemistry and Photobiology A: Chemistry, Numero 453, 2024, Pagina/e 115649, ISSN 1010-6030
Editore: Elsevier BV
DOI: 10.1016/j.jphotochem.2024.115649

Current Perspectives on Synthetic Compartments for Biomedical Applications

Autori: Lukas Heuberger, Maria Korpidou, Olivia M. Eggenberger, Myrto Kyropoulou, Cornelia G. Palivan
Pubblicato in: International Journal of Molecular Sciences, Numero 23, 2024, Pagina/e 5718, ISSN 1422-0067
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105718

Complex Coacervate Materials as Artificial Cells

Autori: Alexander B. Cook, Sebastian Novosedlik, Jan C. M. van Hest
Pubblicato in: Accounts of Materials Research, Numero 4, 2023, Pagina/e 287-298, ISSN 2643-6728
Editore: ACS
DOI: 10.1021/accountsmr.2c00239

Glycooligomer-Functionalized Catalytic Nanocompartments Co-Loaded with Enzymes Support Parallel Reactions and Promote Cell Internalization

Autori: Maria Korpidou, Jonas Becker, Shabnam Tarvirdipour, Ionel Adrian Dinu, C. Remzi Becer, Cornelia G. Palivan
Pubblicato in: Biomacromolecules, Numero 25, 2024, Pagina/e 4492-4509, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.4c00526

Polyproline‐Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism

Autori: Camilla Pegoraro, Ekaterina Karpova, Yusuf Qutbuddin, Esther Masiá Sanchis, Pavels Dimitrijevs, Cristián Huck‐Iriart, Svetozar Gavrilović, Pavel Arsenyan, Petra Schwille, Carles Felip‐León, Aroa Duro‐Castano, Inmaculada Conejos‐Sanchez, María J. Vicent
Pubblicato in: Advanced Materials, Numero 37, 2025, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202411595