Molecular Machines Functioning in Cells

Informacje na temat projektu

BIOMOLMACS

Identyfikator umowy o grant: 859416

DOI

10.3030/859416

Projekt został zamknięty

Data podpisania przez KE 11 Września 2019

Data rozpoczęcia 1 Stycznia 2020

Data zakończenia 30 Czerwca 2024

Finansowanie w ramach

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Koszt całkowity

€ 4 107 786,48

Wkład UE

€ 4 107 786,48

Koordynowany przez

UNIVERSITY OF WARWICK
United Kingdom

CORDIS oferuje możliwość skorzystania z odnośników do publicznie dostępnych publikacji i rezultatów projektów realizowanych w ramach programów ramowych HORYZONT.

Odnośniki do rezultatów i publikacji związanych z poszczególnymi projektami 7PR, a także odnośniki do niektórych konkretnych kategorii wyników, takich jak zbiory danych i oprogramowanie, są dynamicznie pobierane z systemu OpenAIRE .

Rezultaty

Documents, reports (7)

Publication of results in peer-reviewed journals.
Project handbook for ESRs, academics and industrial partners

Project handbook for ESRs academics and industrial partners

Outreach activities and public engagement.
Presentation of results at international conferences.
BIOMOLMACS communication report
Report on training implementation and quality
Training quality assessment checklist

Websites, patent fillings, videos etc. (3)

First online version of the network public website
Project website and online accounts (Twitter, Facebook) to be setup

Project website and online accounts Twitter Facebook to be setup

Advertisement of ESRs on international websites including EurAxess

Open Research Data Pilot (1)

Data management plan

Publikacje

Peer reviewed articles (30)

Designing P-type bi-stable overcrowded alkene-based chiroptical photoswitches

Autorzy: Jinyu Sheng, Wojciech Danowski, Stefano Crespi, Ainoa Guinart, Xiaobing Chen, Cosima Stähler, Ben L. Feringa
Opublikowane w: Chemical Science, Numer 14, 2024, Strona(/y) 4328-4336, ISSN 2041-6520
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2sc05903g

Effect of temperature on glycopolymer and Con A binding properties

Autorzy: Jichuan Chen, Roberto Terracciano, Jonas Becker, Gokhan Yilmaz, C. Remzi Becer
Opublikowane w: European Polymer Journal, Numer 211, 2024, Strona(/y) 113006, ISSN 0014-3057
Wydawca: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2024.113006

Enzymatically-induced dynamic assemblies from surface functional stomatocyte nanoreactors

Autorzy: Alexander D. Fusi, Yudong Li, Marrit M. E. Tholen, Marlo Cieraad, Lorenzo Albertazzi, Tania Patiño Padial, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Opublikowane w: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4tb01320d

Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques

Autorzy: Camilla Pegoraro, Inés Domingo-Ortí, Inmaculada Conejos-Sánchez, María J. Vicent
Opublikowane w: Advanced Drug Delivery Reviews, Numer 207, 2024, Strona(/y) 115195, ISSN 0169-409X
Wydawca: Elsevier BV
DOI: 10.1016/j.addr.2024.115195

Competitive protein recruitment in artificial cells

Autorzy: Thijs W. van Veldhuisen, Madelief A. M. Verwiel, Sebastian Novosedlik, Luc Brunsveld, Jan C. M. van Hest
Opublikowane w: Communications Chemistry, Numer 7, 2024, ISSN 2399-3669
Wydawca: Nature
DOI: 10.1038/s42004-024-01229-9

Design Features to Accelerate the Higher-Order Assembly of DNA Origami on Membranes

Autorzy: Qutbuddin, Yusuf; Krohn, Jan-Hagen; Brüggenthies, Gereon A.; Stein, Johannes; Gavrilovic, Svetozar; Stehr, Florian; Schwille, Petra
Opublikowane w: The Journal of Physical Chemistry B, Numer 125, 48, 2021, Strona(/y) 13181–13191, ISSN 1520-6106
Wydawca: American Chemical Society
DOI: 10.1021/acs.jpcb.1c07694

On the Right “Track” to Artificial Assemblers

Autorzy: Romain Costil, Ainoa Guinart, Ben L. Feringa
Opublikowane w: Chem, Numer 6, 2021, Strona(/y) 2868-2870, ISSN 2451-9294
Wydawca: Cell
DOI: 10.1016/j.chempr.2020.10.016

Step-Growth Glycopolymers with a Defined Tacticity for Selective Carbohydrate–Lectin Recognition

Autorzy: Jonas Becker, Roberto Terracciano, Gokhan Yilmaz, Richard Napier, C. Remzi Becer
Opublikowane w: Biomacromolecules, Numer 24, 2023, Strona(/y) 1924-1933, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.3c00133

Hierarchy of Complex Glycomacromolecules: From Controlled Topologies to Biomedical Applications

Autorzy: Tieshuai Zhao, Roberto Terracciano, Jonas Becker, Alessandra Monaco, Gokhan Yilmaz, C. Remzi Becer
Opublikowane w: Biomacromolecules, Numer 23, 2023, Strona(/y) 543-575, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.1c01294

Achieving Control in Micro‐/Nanomotor Mobility

Autorzy: Alexander D. Fusi, Yudong Li, A. Llopis‐Lorente, Tania Patiño, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Opublikowane w: Angewandte Chemie International Edition, Numer 62, 2023, ISSN 1433-7851
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202214754

Inducing Lipid Domains in Membranes by Self‐Assembly of DNA Origami

Autorzy: Nishu Kanwa, Svetozar Gavrilovic, Gereon A. Brüggenthies, Yusuf Qutbuddin, Petra Schwille
Opublikowane w: Advanced Materials Interfaces, Numer 10, 2023, ISSN 2196-7350
Wydawca: Wiley
DOI: 10.1002/admi.202202500

Highly Efficient Oxindole‐Based Molecular Photoswitches

Autorzy: Daniel Doellerer, Daisy R. S. Pooler, Ainoa Guinart, Stefano Crespi, Ben L. Feringa
Opublikowane w: Chemistry – A European Journal, Numer 29, 2024, ISSN 0947-6539
Wydawca: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202301634

Multifunctional Polypeptide-Based Nanoconjugates for Targeted Mitochondrial Delivery and Nonviral Gene Therapy

Autorzy: Camilla Pegoraro, Esther Masiá Sanchis, Snežana Đorđević, Irene Dolz-Pérez, Cristián Huck-Iriart, Lidia Herrera, Sergio Esteban-Pérez, Inmaculada Conejos-Sanchez, María J. Vicent
Opublikowane w: Chemistry of Materials, Numer 37, 2025, Strona(/y) 1457-1467, ISSN 0897-4756
Wydawca: American Chemical Society
DOI: 10.1021/acs.chemmater.4c02742

Synthetic molecular motor activates drug delivery from polymersomes

Autorzy: Ainoa Guinart, Maria Korpidou, Daniel Doellerer, Gianni Pacella, Marc C. A. Stuart, Ionel Adrian Dinu, Giuseppe Portale, Cornelia Palivan, Ben L. Feringa
Opublikowane w: Proceedings of the National Academy of Sciences, Numer 120, 2023, ISSN 0027-8424
Wydawca: National Academy of Sciences
DOI: 10.1073/pnas.2301279120

Poly(2-oxazoline)-Based Thermoresponsive Stomatocytes

Autorzy: Roberto Terracciano, Yuechi Liu, Zivani Varanaraja, Magdalena Godzina, Gokhan Yilmaz, Jan C. M. van Hest, C. Remzi Becer
Opublikowane w: Biomacromolecules, 2024, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.4c00726

Light‐Activated Synthetic Rotary Motors in Lipid Membranes Induce Shape Changes Through Membrane Expansion

Autorzy: Yusuf Qutbuddin, Ainoa Guinart, Svetozar Gavrilović, Kareem Al Nahas, Ben L. Feringa, Petra Schwille
Opublikowane w: Advanced Materials, Numer 36, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202311176

Degradable thioester core-crosslinked star-shaped polymers

Autorzy: Matthew Laurel, Daniel MacKinnon, Jonas Becker, Roberto Terracciano, Ben Drain, Hannes A. Houck, C. Remzi Becer
Opublikowane w: Polymer Chemistry, Numer 13, 2024, Strona(/y) 5579-5589, ISSN 1759-9954
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2py00901c

Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery

Autorzy: Graham Hayes, Beatriz Dias-Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Opublikowane w: Biomacromolecules, Numer 24, 2023, Strona(/y) 5142-5151, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.3c00683

A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake

Autorzy: Camilla Pegoraro, Ainoa Guinart, Esther Masiá Sanchis, Daniel Doellerer, Marc C. A. Stuart, Inmaculada Conejos-Sánchez, Ben L. Feringa, María J. Vicent
Opublikowane w: Journal of Materials Chemistry B, Numer 13, 2025, Strona(/y) 2658-2665, ISSN 2050-7518
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d4tb02434f

Inverting glucuronidation of hymecromone <i>in situ</i> by catalytic nanocompartments

Autorzy: Maria Korpidou, Viviana Maffeis, Ionel Adrian Dinu, Cora-Ann Schoenenberger, Wolfgang P. Meier, Cornelia G. Palivan
Opublikowane w: Journal of Materials Chemistry B, Numer 10, 2024, Strona(/y) 3916-3926, ISSN 2050-7518
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d2tb00243d

Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles

Autorzy: Clémence Schvartzman, Emmanuel Ibarboure, Anouk Martin, Elisabeth Garanger, Angela Mutschler, Sébastien Lecommandoux
Opublikowane w: Biomacromolecules, Numer 25, 2024, Strona(/y) 4087-4094, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.4c00200

Control of Enzyme Reactivity in Response to Osmotic Pressure Modulation Mimicking Dynamic Assembly of Intracellular Organelles

Autorzy: Clémence Schvartzman, Hang Zhao, Emmanuel Ibarboure, Vusala Ibrahimova, Elisabeth Garanger, Sébastien Lecommandoux
Opublikowane w: Advanced Materials, Numer 35, 2024, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202301856

Utilization of Anthracene-Functionalized Poly(2-oxazolines) as a Dispersant of Carbon Black in Water and Dodecane

Autorzy: Zivani Varanaraja, Roberto Terracciano, Nathan Hollingsworth, Ross Green, James Beament, C. Remzi Becer
Opublikowane w: Macromolecules, Numer 57, 2024, Strona(/y) 5769-5779, ISSN 0024-9297
Wydawca: American Chemical Society
DOI: 10.1021/acs.macromol.4c00843

Self-Assembly Behavior of Amphiphilic Poly(2-ethyl-2-oxazoline)-<i>b</i>-poly(2-isostearyl-2-oxazoline) Block Copolymers

Autorzy: James Lefley, Roberto Terracciano, Zivani Varanaraja, James Beament, C. Remzi Becer
Opublikowane w: Macromolecules, Numer 57, 2024, Strona(/y) 5881-5891, ISSN 0024-9297
Wydawca: American Chemical Society
DOI: 10.1021/acs.macromol.4c00833

Degradable glycopolymers for saRNA transfection

Autorzy: Alessandra Monaco, Beatriz Dias Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Opublikowane w: Polymer Chemistry, Numer 14, 2024, Strona(/y) 2750-2761, ISSN 1759-9954
Wydawca: Royal Society of Chemistry
DOI: 10.1039/d3py00260h

Two-photon absorption of oxindole-based push–pull molecular motors

Autorzy: Ainoa Guinart, Daniel Doellerer, Daisy R.S. Pooler, John Y. de Boer, Sandra Doria, Laura Bussotti, Mariangela Di Donato, Ben L. Feringa
Opublikowane w: Journal of Photochemistry and Photobiology A: Chemistry, Numer 453, 2024, Strona(/y) 115649, ISSN 1010-6030
Wydawca: Elsevier BV
DOI: 10.1016/j.jphotochem.2024.115649

Current Perspectives on Synthetic Compartments for Biomedical Applications

Autorzy: Lukas Heuberger, Maria Korpidou, Olivia M. Eggenberger, Myrto Kyropoulou, Cornelia G. Palivan
Opublikowane w: International Journal of Molecular Sciences, Numer 23, 2024, Strona(/y) 5718, ISSN 1422-0067
Wydawca: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105718

Complex Coacervate Materials as Artificial Cells

Autorzy: Alexander B. Cook, Sebastian Novosedlik, Jan C. M. van Hest
Opublikowane w: Accounts of Materials Research, Numer 4, 2023, Strona(/y) 287-298, ISSN 2643-6728
Wydawca: ACS
DOI: 10.1021/accountsmr.2c00239

Glycooligomer-Functionalized Catalytic Nanocompartments Co-Loaded with Enzymes Support Parallel Reactions and Promote Cell Internalization

Autorzy: Maria Korpidou, Jonas Becker, Shabnam Tarvirdipour, Ionel Adrian Dinu, C. Remzi Becer, Cornelia G. Palivan
Opublikowane w: Biomacromolecules, Numer 25, 2024, Strona(/y) 4492-4509, ISSN 1525-7797
Wydawca: American Chemical Society
DOI: 10.1021/acs.biomac.4c00526

Polyproline‐Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism

Autorzy: Camilla Pegoraro, Ekaterina Karpova, Yusuf Qutbuddin, Esther Masiá Sanchis, Pavels Dimitrijevs, Cristián Huck‐Iriart, Svetozar Gavrilović, Pavel Arsenyan, Petra Schwille, Carles Felip‐León, Aroa Duro‐Castano, Inmaculada Conejos‐Sanchez, María J. Vicent
Opublikowane w: Advanced Materials, Numer 37, 2025, ISSN 0935-9648
Wydawca: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202411595