Molecular Machines Functioning in Cells

Información del proyecto

BIOMOLMACS

Identificador del acuerdo de subvención: 859416

DOI

10.3030/859416

Proyecto cerrado

Fecha de la firma de la CE 11 Septiembre 2019

Fecha de inicio 1 Enero 2020

Fecha de finalización 30 Junio 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 107 786,48

Aportación de la UE

€ 4 107 786,48

Coordinado por

UNIVERSITY OF WARWICK
United Kingdom

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Documents, reports (7)

Publication of results in peer-reviewed journals.
Project handbook for ESRs, academics and industrial partners

Project handbook for ESRs academics and industrial partners

Outreach activities and public engagement.
Presentation of results at international conferences.
BIOMOLMACS communication report
Report on training implementation and quality
Training quality assessment checklist

Websites, patent fillings, videos etc. (3)

First online version of the network public website
Project website and online accounts (Twitter, Facebook) to be setup

Project website and online accounts Twitter Facebook to be setup

Advertisement of ESRs on international websites including EurAxess

Open Research Data Pilot (1)

Data management plan

Publicaciones

Peer reviewed articles (30)

Designing P-type bi-stable overcrowded alkene-based chiroptical photoswitches

Autores: Jinyu Sheng, Wojciech Danowski, Stefano Crespi, Ainoa Guinart, Xiaobing Chen, Cosima Stähler, Ben L. Feringa
Publicado en: Chemical Science, Edición 14, 2024, Página(s) 4328-4336, ISSN 2041-6520
Editor: Royal Society of Chemistry
DOI: 10.1039/d2sc05903g

Effect of temperature on glycopolymer and Con A binding properties

Autores: Jichuan Chen, Roberto Terracciano, Jonas Becker, Gokhan Yilmaz, C. Remzi Becer
Publicado en: European Polymer Journal, Edición 211, 2024, Página(s) 113006, ISSN 0014-3057
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.eurpolymj.2024.113006

Enzymatically-induced dynamic assemblies from surface functional stomatocyte nanoreactors

Autores: Alexander D. Fusi, Yudong Li, Marrit M. E. Tholen, Marlo Cieraad, Lorenzo Albertazzi, Tania Patiño Padial, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Publicado en: Journal of Materials Chemistry B, 2024, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/d4tb01320d

Unlocking the Mitochondria for Nanomedicine-based Treatments: Overcoming Biological Barriers, Improving Designs, and Selecting Verification Techniques

Autores: Camilla Pegoraro, Inés Domingo-Ortí, Inmaculada Conejos-Sánchez, María J. Vicent
Publicado en: Advanced Drug Delivery Reviews, Edición 207, 2024, Página(s) 115195, ISSN 0169-409X
Editor: Elsevier BV
DOI: 10.1016/j.addr.2024.115195

Competitive protein recruitment in artificial cells

Autores: Thijs W. van Veldhuisen, Madelief A. M. Verwiel, Sebastian Novosedlik, Luc Brunsveld, Jan C. M. van Hest
Publicado en: Communications Chemistry, Edición 7, 2024, ISSN 2399-3669
Editor: Nature
DOI: 10.1038/s42004-024-01229-9

Design Features to Accelerate the Higher-Order Assembly of DNA Origami on Membranes

Autores: Qutbuddin, Yusuf; Krohn, Jan-Hagen; Brüggenthies, Gereon A.; Stein, Johannes; Gavrilovic, Svetozar; Stehr, Florian; Schwille, Petra
Publicado en: The Journal of Physical Chemistry B, Edición 125, 48, 2021, Página(s) 13181–13191, ISSN 1520-6106
Editor: American Chemical Society
DOI: 10.1021/acs.jpcb.1c07694

On the Right “Track” to Artificial Assemblers

Autores: Romain Costil, Ainoa Guinart, Ben L. Feringa
Publicado en: Chem, Edición 6, 2021, Página(s) 2868-2870, ISSN 2451-9294
Editor: Cell
DOI: 10.1016/j.chempr.2020.10.016

Step-Growth Glycopolymers with a Defined Tacticity for Selective Carbohydrate–Lectin Recognition

Autores: Jonas Becker, Roberto Terracciano, Gokhan Yilmaz, Richard Napier, C. Remzi Becer
Publicado en: Biomacromolecules, Edición 24, 2023, Página(s) 1924-1933, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00133

Hierarchy of Complex Glycomacromolecules: From Controlled Topologies to Biomedical Applications

Autores: Tieshuai Zhao, Roberto Terracciano, Jonas Becker, Alessandra Monaco, Gokhan Yilmaz, C. Remzi Becer
Publicado en: Biomacromolecules, Edición 23, 2023, Página(s) 543-575, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.1c01294

Achieving Control in Micro‐/Nanomotor Mobility

Autores: Alexander D. Fusi, Yudong Li, A. Llopis‐Lorente, Tania Patiño, Jan C. M. van Hest, Loai K. E. A. Abdelmohsen
Publicado en: Angewandte Chemie International Edition, Edición 62, 2023, ISSN 1433-7851
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202214754

Inducing Lipid Domains in Membranes by Self‐Assembly of DNA Origami

Autores: Nishu Kanwa, Svetozar Gavrilovic, Gereon A. Brüggenthies, Yusuf Qutbuddin, Petra Schwille
Publicado en: Advanced Materials Interfaces, Edición 10, 2023, ISSN 2196-7350
Editor: Wiley
DOI: 10.1002/admi.202202500

Highly Efficient Oxindole‐Based Molecular Photoswitches

Autores: Daniel Doellerer, Daisy R. S. Pooler, Ainoa Guinart, Stefano Crespi, Ben L. Feringa
Publicado en: Chemistry – A European Journal, Edición 29, 2024, ISSN 0947-6539
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202301634

Multifunctional Polypeptide-Based Nanoconjugates for Targeted Mitochondrial Delivery and Nonviral Gene Therapy

Autores: Camilla Pegoraro, Esther Masiá Sanchis, Snežana Đorđević, Irene Dolz-Pérez, Cristián Huck-Iriart, Lidia Herrera, Sergio Esteban-Pérez, Inmaculada Conejos-Sanchez, María J. Vicent
Publicado en: Chemistry of Materials, Edición 37, 2025, Página(s) 1457-1467, ISSN 0897-4756
Editor: American Chemical Society
DOI: 10.1021/acs.chemmater.4c02742

Synthetic molecular motor activates drug delivery from polymersomes

Autores: Ainoa Guinart, Maria Korpidou, Daniel Doellerer, Gianni Pacella, Marc C. A. Stuart, Ionel Adrian Dinu, Giuseppe Portale, Cornelia Palivan, Ben L. Feringa
Publicado en: Proceedings of the National Academy of Sciences, Edición 120, 2023, ISSN 0027-8424
Editor: National Academy of Sciences
DOI: 10.1073/pnas.2301279120

Poly(2-oxazoline)-Based Thermoresponsive Stomatocytes

Autores: Roberto Terracciano, Yuechi Liu, Zivani Varanaraja, Magdalena Godzina, Gokhan Yilmaz, Jan C. M. van Hest, C. Remzi Becer
Publicado en: Biomacromolecules, 2024, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.4c00726

Light‐Activated Synthetic Rotary Motors in Lipid Membranes Induce Shape Changes Through Membrane Expansion

Autores: Yusuf Qutbuddin, Ainoa Guinart, Svetozar Gavrilović, Kareem Al Nahas, Ben L. Feringa, Petra Schwille
Publicado en: Advanced Materials, Edición 36, 2024, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202311176

Degradable thioester core-crosslinked star-shaped polymers

Autores: Matthew Laurel, Daniel MacKinnon, Jonas Becker, Roberto Terracciano, Ben Drain, Hannes A. Houck, C. Remzi Becer
Publicado en: Polymer Chemistry, Edición 13, 2024, Página(s) 5579-5589, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/d2py00901c

Poly(2-oxazoline)/saRNA Polyplexes for Targeted and Nonviral Gene Delivery

Autores: Graham Hayes, Beatriz Dias-Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Publicado en: Biomacromolecules, Edición 24, 2023, Página(s) 5142-5151, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.3c00683

A light-driven molecular motor-polypeptide conjugate supports controlled cell uptake

Autores: Camilla Pegoraro, Ainoa Guinart, Esther Masiá Sanchis, Daniel Doellerer, Marc C. A. Stuart, Inmaculada Conejos-Sánchez, Ben L. Feringa, María J. Vicent
Publicado en: Journal of Materials Chemistry B, Edición 13, 2025, Página(s) 2658-2665, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/d4tb02434f

Inverting glucuronidation of hymecromone <i>in situ</i> by catalytic nanocompartments

Autores: Maria Korpidou, Viviana Maffeis, Ionel Adrian Dinu, Cora-Ann Schoenenberger, Wolfgang P. Meier, Cornelia G. Palivan
Publicado en: Journal of Materials Chemistry B, Edición 10, 2024, Página(s) 3916-3926, ISSN 2050-7518
Editor: Royal Society of Chemistry
DOI: 10.1039/d2tb00243d

Protocells Featuring Membrane-Bound and Dynamic Membraneless Organelles

Autores: Clémence Schvartzman, Emmanuel Ibarboure, Anouk Martin, Elisabeth Garanger, Angela Mutschler, Sébastien Lecommandoux
Publicado en: Biomacromolecules, Edición 25, 2024, Página(s) 4087-4094, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.4c00200

Control of Enzyme Reactivity in Response to Osmotic Pressure Modulation Mimicking Dynamic Assembly of Intracellular Organelles

Autores: Clémence Schvartzman, Hang Zhao, Emmanuel Ibarboure, Vusala Ibrahimova, Elisabeth Garanger, Sébastien Lecommandoux
Publicado en: Advanced Materials, Edición 35, 2024, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202301856

Utilization of Anthracene-Functionalized Poly(2-oxazolines) as a Dispersant of Carbon Black in Water and Dodecane

Autores: Zivani Varanaraja, Roberto Terracciano, Nathan Hollingsworth, Ross Green, James Beament, C. Remzi Becer
Publicado en: Macromolecules, Edición 57, 2024, Página(s) 5769-5779, ISSN 0024-9297
Editor: American Chemical Society
DOI: 10.1021/acs.macromol.4c00843

Self-Assembly Behavior of Amphiphilic Poly(2-ethyl-2-oxazoline)-<i>b</i>-poly(2-isostearyl-2-oxazoline) Block Copolymers

Autores: James Lefley, Roberto Terracciano, Zivani Varanaraja, James Beament, C. Remzi Becer
Publicado en: Macromolecules, Edición 57, 2024, Página(s) 5881-5891, ISSN 0024-9297
Editor: American Chemical Society
DOI: 10.1021/acs.macromol.4c00833

Degradable glycopolymers for saRNA transfection

Autores: Alessandra Monaco, Beatriz Dias Barbieri, Gokhan Yilmaz, Robin J. Shattock, C. Remzi Becer
Publicado en: Polymer Chemistry, Edición 14, 2024, Página(s) 2750-2761, ISSN 1759-9954
Editor: Royal Society of Chemistry
DOI: 10.1039/d3py00260h

Two-photon absorption of oxindole-based push–pull molecular motors

Autores: Ainoa Guinart, Daniel Doellerer, Daisy R.S. Pooler, John Y. de Boer, Sandra Doria, Laura Bussotti, Mariangela Di Donato, Ben L. Feringa
Publicado en: Journal of Photochemistry and Photobiology A: Chemistry, Edición 453, 2024, Página(s) 115649, ISSN 1010-6030
Editor: Elsevier BV
DOI: 10.1016/j.jphotochem.2024.115649

Current Perspectives on Synthetic Compartments for Biomedical Applications

Autores: Lukas Heuberger, Maria Korpidou, Olivia M. Eggenberger, Myrto Kyropoulou, Cornelia G. Palivan
Publicado en: International Journal of Molecular Sciences, Edición 23, 2024, Página(s) 5718, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23105718

Complex Coacervate Materials as Artificial Cells

Autores: Alexander B. Cook, Sebastian Novosedlik, Jan C. M. van Hest
Publicado en: Accounts of Materials Research, Edición 4, 2023, Página(s) 287-298, ISSN 2643-6728
Editor: ACS
DOI: 10.1021/accountsmr.2c00239

Glycooligomer-Functionalized Catalytic Nanocompartments Co-Loaded with Enzymes Support Parallel Reactions and Promote Cell Internalization

Autores: Maria Korpidou, Jonas Becker, Shabnam Tarvirdipour, Ionel Adrian Dinu, C. Remzi Becer, Cornelia G. Palivan
Publicado en: Biomacromolecules, Edición 25, 2024, Página(s) 4492-4509, ISSN 1525-7797
Editor: American Chemical Society
DOI: 10.1021/acs.biomac.4c00526

Polyproline‐Polyornithine Diblock Copolymers with Inherent Mitochondria Tropism

Autores: Camilla Pegoraro, Ekaterina Karpova, Yusuf Qutbuddin, Esther Masiá Sanchis, Pavels Dimitrijevs, Cristián Huck‐Iriart, Svetozar Gavrilović, Pavel Arsenyan, Petra Schwille, Carles Felip‐León, Aroa Duro‐Castano, Inmaculada Conejos‐Sanchez, María J. Vicent
Publicado en: Advanced Materials, Edición 37, 2025, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202411595