The Medical Digital Twin for Aneurysm Prevention and Treatment

Informations projet

MeDiTATe

N° de convention de subvention: 859836

DOI

10.3030/859836

Projet clôturé

Date de signature de la CE 11 Septembre 2019

Date de début 1 Janvier 2020

Date de fin 30 Juin 2024

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 3 750 403,86

Contribution de l’UE

€ 3 750 403,86

Coordonné par

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Italy

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Publications

Book chapters (1)

Advanced Radial Basis Functions Mesh Morphing for High Fidelity Fluid-Structure Interaction with Known Movement of the Walls: Simulation of an Aortic Valve

Auteurs: Leonardo Geronzi, Emanuele Gasparotti, Katia Capellini, Ubaldo Cella, Corrado Groth, Stefano Porziani, Andrea Chiappa, Simona Celi, Marco Evangelos Biancolini
Publié dans: Lecture Notes in Computer Science, Computational Science – ICCS 2020, 2024, Page(s) 280-293
Éditeur: Springer International Publishing
DOI: 10.1007/978-3-030-50433-5_22

Peer reviewed articles (30)

The Hemodynamic Effect of Modified Blalock–Taussig Shunt Morphologies: A Computational Analysis Based on Reduced Order Modeling

Auteurs: Eirini Kardampiki; Emanuele Vignali; Dorela Haxhiademi; Duccio Federici; Edoardo Ferrante; Stefano Porziani; Andrea Chiappa; Corrado Groth; Margherita Cioffi; Marco Evangelos Biancolini; Emiliano Costa; Simona Celi
Publié dans: Electronics; Volume 11; Numéro 13; Pages: 1930, Numéro 5, 2022, ISSN 2078-2489
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/electronics11131930

Fast interactive CFD evaluation of hemodynamics assisted by RBF mesh morphing and reduced order models: the case of aTAA modelling

Auteurs: Marco Evangelos Biancolini; Katia Capellini; Emiliano Costa; Corrado Groth; Simona Celi
Publié dans: International Journal on Interactive Design and Manufacturing (IJIDeM), Numéro 14, 2020, Page(s) 1227–1238, ISSN 1955-2513
Éditeur: Springer Verlag
DOI: 10.1007/s12008-020-00694-5

Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating

Auteurs: Beatrice Bisighini, Pierluigi Di Giovanni Alba Scerrati ,Federica Trovalusci and Silvia Vesco
Publié dans: Materials 2023, 16(1), 166, 2023, ISSN 1996-1944
Éditeur: MDPI Open Access Publishing
DOI: 10.3390/ma16010166

Segmentation of the aorta in systolic phase from 4D flow MRI: multi-atlas vs. deep learning

Auteurs: Diana M Marin-Castrillon Leonardo Geronzi Arnaud Boucher Siyu Lin Marie-Catherine Morgant Alexandre Cochet Michel Rochette Sarah Leclerc Khalid Ambarki Ning Jin Ludwig Serge Aho Glele Alain Lalande Olivier Bouchot Benoît Presles
Publié dans: MAGMA . 2023 Oct;36(5):687-700, 2023, ISSN 0968-5243
Éditeur: Springer Verlag
DOI: 10.1007/s10334-023-01066-2

Machine learning and reduced order modelling for the simulation of braided stent deployment

Auteurs: Beatrice Bisighini; Beatrice Bisighini; Beatrice Bisighini; Miquel Aguirre; Miquel Aguirre; Miquel Aguirre; Marco Evangelos Biancolini; Federica Trovalusci; David Perrin; Stéphane Avril; Baptiste Pierrat
Publié dans: Frontiers in Physiology, Vol 14 (2023), Numéro 1, 2023, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1148540

Calibration of the Mechanical Boundary Conditions for a Patient-Specific Thoracic Aorta Model Including the Heart Motion Effect

Auteurs: Leonardo Geronzi, Aline Bel-Brunon, Antonio Martinez, Michel Rochette, Marco Sensale, Olivier Bouchot, Alain Lalande, Siyu Lin, Pier Paolo Valentini, Marco Evangelos Biancolini
Publié dans: IEEE Trans Biomed Eng . 2023 Nov;70(11):3248-3259., 2023, ISSN 0018-9294
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2023.3287680

Computational Comparison of the Mechanical Behavior of Aortic Stent-Grafts Derived from Auxetic Unit Cells

Auteurs: Rahul Vellaparambil; Woo-Suck Han; Pierluigi Di Giovanni; Stéphane Avril
Publié dans: Cardiovascular Engineering and Technology (2024) 15:199–210, Numéro 1, 2024, ISSN 1869-408X
Éditeur: Springer Pub. Co.,
DOI: 10.1007/s13239-023-00706-x

Aortic roadmapping during EVAR: a combined FEM–EM tracking feasibility study

Auteurs: Monica Emendi, Geir A. Tangen, Pierluigi Di Giovanni, Håvard Ulsaker, Reidar Brekken, Frode Manstad-Hulaas, Victorien Prot, Aline Bel-Brunon, Karen H. Støverud
Publié dans: International Journal of Computer Assisted Radiology and Surgery, Numéro 19, 2024, Page(s) 2239-2247, ISSN 1861-6429
Éditeur: Springer
DOI: 10.1007/s11548-024-03187-y

Uncertainty Quantification in the In Vivo Image-Based Estimation of Local Elastic Properties of Vascular Walls

Auteurs: Benigno Marco Fanni; Maria Nicole Antonuccio; Alessandra Pizzuto; Sergio Berti; Giuseppe Santoro; Simona Celi
Publié dans: Journal of Cardiovascular Development and Disease; Volume 10; Numéro 3; Pages: 109, Numéro 1, 2023, ISSN 2078-2489
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcdd10030109

Patient-specific computational modelling of endovascular treatment for intracranial aneurysms”

Auteurs: Beatrice Bisighini, Miquel Aguirre, Baptiste Pierrat Stéphane Avril
Publié dans: Brain Multiphysics Volume 5, December 2023, 100079, 2023, ISSN 0346-251X
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.brain.2023.100079

Towards a reduced order model for EVAR planning and intra-operative navigation

Auteurs: Monica Emendi, Eirini Kardampiki, Karen-Helene Støverud, Antonio Martinez Pascual, Leonardo Geronzi, Sigrid Kaarstad Dahl, Victorien Prot, Paal Skjetne, Marco Evangelos Biancolini
Publié dans: Medical Engineering & Physics, Numéro 131, 2024, Page(s) 104229, ISSN 1350-4533
Éditeur: Elsevier BV
DOI: 10.1016/j.medengphy.2024.104229

An image-based approach for the estimation of arterial local stiffness in vivo

Auteurs: Simona Celi; Emanuele Gasparotti; Katia Capellini; Francesco Bardi; Francesco Bardi; Martino Andrea Scarpolini; Martino Andrea Scarpolini; Carlo Cavaliere; Filippo Cademartiri; Emanuele Vignali
Publié dans: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023), Numéro 1, 2023, ISSN 2296-4185
Éditeur: Pubmed
DOI: 10.3389/fbioe.2023.1096196

Fast strain mapping in abdominal aortic aneurysm wall reveals heterogeneous patterns

Auteurs: Marta Irene Bracco; Marta Irene Bracco; Magdalena Broda; Ulver Spangsberg Lorenzen; Mateusz Cezary Florkow; Oudom Somphone; Stephane Avril; Marco Evangelos Biancolini; Laurence Rouet
Publié dans: Frontiers in Physiology, Vol 14 (2023), Numéro 1, 2023, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1163204

Numerical simulation of aortic coarctations of different grades of severity: Flow features and importance of outlet boundary conditions

Auteurs: Mariotti A.; Antonuccio M. N.; Morello M.; Salvetti M. V.; Celi S.
Publié dans: Computers & Fluids Volume 266, 15 November 2023, 106043, Numéro 1, 2023, ISSN 0346-251X
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.compfluid.2023.106043

Enabling supra-aortic vessels inclusion in statistical shape models of the aorta: a novel non-rigid registration method

Auteurs: Martino Andrea Scarpolini,Marilena Mazzoli,Simona Celi
Publié dans: Front. Physiol., 10 August 2023 Sec. Computational Physiology and Medicine Volume 14 - 2023 |, 2023, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1211461

An RBF Meshless Approach to Evaluate Strain Due to Large Displacements in Flexible Printed Circuit Boards

Auteurs: Groth C.; Chiappa A.; Porziani S.; Salvini P.; Biancolini M. E.
Publié dans: Micromachines, Vol 13, Iss 8, p 1163 (2022), Numéro 1, 2022, ISSN 2072-666X
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi13081163

Prediction of guidewire-induced aortic deformations during EVAR: a finite element and in vitro study

Auteurs: Monica Emendi; Monica Emendi; Karen H. Støverud; Geir A. Tangen; Håvard Ulsaker; Frode Manstad-H; Frode Manstad-H; Pierluigi Di Giovanni; Sigrid K. Dahl; Thomas Langø; Victorien Prot
Publié dans: Frontiers in Physiology, Vol 14 (2023), Numéro 1, 2023, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1098867

Assessment of shape-based features ability to predict the ascending aortic aneurysm growth

Auteurs: Leonardo Geronzi; Leonardo Geronzi; Pascal Haigron; Antonio Martinez; Antonio Martinez; Kexin Yan; Kexin Yan; Michel Rochette; Aline Bel-Brunon; Jean Porterie; Siyu Lin; Siyu Lin; Diana Marcela Marin-Castrillon; Diana Marcela Marin-Castrillon; Alain Lalande; Alain Lalande; Olivier Bouchot; Morgan Daniel; Pierre Escrig; Jacques Tomasi; Pier Paolo Valentini; Marco Evangelos Biancolini
Publié dans: Frontiers in Physiology, Vol 14 (2023), Numéro 1, 2023, ISSN 1664-042X
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1125931

A Hybrid Mock Circulatory Loop for Fluid Dynamic Characterization of 3D Anatomical Phantoms

Auteurs: Francesco Bardi; Emanuele Gasparotti; Emanuele Vignali; Stéphane Avril; Simona Celi
Publié dans: IEEE Transactions on Biomedical Engineering ( Volume: 70, Numéro: 5, May 2023), 2023, ISSN 0018-9294
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2022.3224581

Computer-aided shape features extraction and regression models for predicting the ascending aortic aneurysm growth rate

Auteurs: Leonardo Geronzi a b, Antonio Martinez a b, Michel Rochette b, Kexin Yan b c, Aline Bel-Brunon c, Pascal Haigron d, Pierre Escrig d, Jacques Tomasi d, Morgan Daniel d, Alain Lalande e f, Siyu Lin e f, Diana Marcela Marin-Castrillon e f, Olivier Bouchot g, Jean Porterie h, Pier Paolo Valentini a, Marco Evangelos Biancolini a
Publié dans: Computers in Biology and Medicine Volume 162, August 2023, 107052, 2023, ISSN 0010-4825
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2023.107052

EndoBeams.jl: A Julia finite element package for beam-to-surface contact problems in cardiovascular mechanics

Auteurs: Beatrice Bisighini; Miquel Aguirre; Baptiste Pierrat; David Perrin; Stéphane Avril
Publié dans: Advances in Engineering Software Volume 171, September 2022, 103173, Numéro 1, 2022, ISSN 0965-9978
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.advengsoft.2022.103173

Ultrasound Probe Pressure Affects Aortic Wall Stiffness: A Patient-Specific Computational Study in Abdominal Aortic Aneurysms

Auteurs: Marta Irene Bracco, Ali Akbar Karkhaneh Yousefi, Laurence Rouet, Stéphane Avril
Publié dans: Annals of Biomedical Engineering, Numéro 53, 2025, Page(s) 71-82, ISSN 0090-6964
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10439-024-03608-8

Coupling synthetic and real-world data for a deep learning-based segmentation process of 4D flow MRI

Auteurs: Simone Garzia; Martino Andrea Scarpolini; Marilena Mazzoli; Katia Capellini; Angelo Monteleone; Filippo Cademartiri; Vincenzo Positano; Simona Celi
Publié dans: Computer Methods and Programs in Biomedicine Volume 242, December 2023, 107790, Numéro 1, 2023, ISSN 0346-251X
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.cmpb.2023.107790

High fidelity fluid-structure interaction by radial basis functions mesh adaption of moving walls: A workflow applied to an aortic valve

Auteurs: Leonardo Geronzi, Emanuele Gasparotti, Katia Capellini, Ubaldo Cella, Corrado Groth, Stefano Porziani, Andrea Chiappa, Simona Celi, Marco Evangelos Biancolini
Publié dans: Journal of Computational Science, Numéro Volume 51, 2021, ISSN 1877-7503
Éditeur: Elsevier BV
DOI: 10.1016/j.jocs.2021.101327

Experimental validation of auxetic stent designs: three-point bending of 3D printed Titanium prototypes

Auteurs: Rahul Vellaparambil,Woo-Suck Han Pierluigi Di Giovanni Stéphane Avril
Publié dans: Front. Med. Technol., 06 May 2024 Sec. Cardiovascular Medtech Volume 6 - 2024 |, 2024, ISSN 2673-3129
Éditeur: Frontiers in Medical Technology
DOI: 10.3389/fmedt.2024.1388207

Fabrication of deformable patient-specific AAA models by material casting techniques

Auteurs: Maria Nicole Antonuccio Emanuele Gasparotti , Francesco Bardi Angelo Monteleone , Alexandre This Laurence Rouet Stéphane Avril , Simona Celi
Publié dans: Front Cardiovasc Med . 2023 Sep 11:10:1141623., 2023, ISSN 2813-5911
Éditeur: Lausanne: Frontiers Media S.A.
DOI: 10.3389/fcvm.2023.1141623

A novel formulation for the study of the ascending aortic fluid dynamics with in vivo data

Auteurs: Katia Capellini, Emanuele Gasparotti, Ubaldo Cella, Emiliano Costa, Benigno Marco Fanni, Corrado Groth, Stefano Porziani, Marco Evangelos Biancolini, Simona Celi
Publié dans: Medical Engineering & Physics, Numéro Volume 91, 2021, Page(s) 68-78, ISSN 1350-4533
Éditeur: Elsevier BV
DOI: 10.1016/j.medengphy.2020.09.005

Potential of Auxetic Designs in Endovascular Aortic Repair: A Computational Study of Their Mechanical Performance

Auteurs: Rahul Vellaparambil; Woo-Suck Han; Pierluigi Di Giovanni; Stéphane Avril
Publié dans: Journal of the Mechanical Behavior of Biomedical Materials, Numéro 1, 2023, ISSN 1751-6161
Éditeur: Elsevier BV
DOI: 10.2139/ssrn.4258753

HPC+ in the medical field: Overview and current examples

Auteurs: Koch, Miriam; Arlandini, Claudio; Antonopoulos, Gregory; Baretta, Alessia; Beaujean, Pierre; BEX, Geert Jan; Biancolini, Marco Evangelos; Celi, Simona; Costa, Emiliano; Drescher, Lukas; Eleftheriadis, Vasileios; Fadel, Nur A.; Fink, Andreas; Galbiati, Federica; Hatzakis, Ilias; Hompis, Georgios; Lewandowski, Natalie; Memmolo, Antonio; Mensch, Carl; Obrist, Dominik; Paneta, Valentina; Papadimitroul
Publié dans: Technology and Health Care 31 (2023) 1509–1523, Numéro 2, 2023, ISSN 0928-7329
Éditeur: IOS Press
DOI: 10.3233/thc-229015

Towards the 2D velocity reconstruction in abdominal aorta from Color-Doppler Ultrasound

Auteurs: Maria Nicole Antonuccio; Hernan G. Morales; Alexandre This; Katia Capellini; Stéphane Avril; Simona Celi; Laurence Rouet
Publié dans: Medical Engineering & Physics Volume 107, September 2022, 103873, Numéro 1, 2022, ISSN 1350-4533
Éditeur: Elsevier BV
DOI: 10.1016/j.medengphy.2022.103873

Other (3)

Aortic Wall Stiffness Depends on Ultrasound Probe Pressure

Auteurs: Bracco, Marta, Irene; Eiberg, Jonas, Peter; Lorenzen, Ulver, Spangsberg; Avril, Stephane; Rouet, Laurence
Publié dans: Medical Physics (physics.med-ph) arXiv:2312.07980 [physics.med-ph], Numéro 1, 2023
Éditeur: Medical Physics
DOI: 10.48550/arxiv.2312.07980

Impact of the Spatial Velocity Inlet Distribution on the Hemodynamics of the Thoracic Aorta

Auteurs: Mariotti A.; Celi S.; Antonuccio M. N.; Salvetti M. V.
Publié dans: Cardiovascular Engineering and Technology,2023 Oct;14(5):713-725., Numéro 1, 2023, ISSN 1539-3704
Éditeur: Pubmed
DOI: 10.1007/s13239-023-00682-2

Effect of turbulence and viscosity models on wall shear stress derived biomarkers for aorta simulations

Auteurs: Martínez A.; Hoeijmakers M.; Geronzi L.; Morgenthaler V.; Tomasi J.; Rochette M.; Biancolini M. E.
Publié dans: "Computers in Biology and Medicine, 2023, Computers in Biology and Medicine, 167, pp.107603. ⟨10.1016/j.compbiomed.2023.107603⟩", Numéro 1, 2023
Éditeur: https://hal.science/
DOI: 10.1016/j.compbiomed.2023.107603

Droits de propriété intellectuelle

Patent (3)

METHOD FOR SIMULATING A DEVICE DEPLOYMENT

Numéro de demande/publication: 22 305140
Date: 2022-02-09
Demandeur(s): PREDISURGE

METHOD FOR SIMULATING A DEVICE DEPLOYMENT

Numéro de demande/publication: 22 305140
Date: 2022-02-09
Demandeur(s): ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS

AORTIC ABDOMINAL ANEURYSM BIOMARKERS

Numéro de demande/publication: 21 290095
Date: 2021-12-21
Demandeur(s): PHILIPS FRANCE