The Medical Digital Twin for Aneurysm Prevention and Treatment

Información del proyecto

MeDiTATe

Identificador del acuerdo de subvención: 859836

DOI

10.3030/859836

Proyecto cerrado

Fecha de la firma de la CE 11 Septiembre 2019

Fecha de inicio 1 Enero 2020

Fecha de finalización 30 Junio 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 3 750 403,86

Aportación de la UE

€ 3 750 403,86

Coordinado por

UNIVERSITA DEGLI STUDI DI ROMA TOR VERGATA
Italy

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Book chapters (1)

Advanced Radial Basis Functions Mesh Morphing for High Fidelity Fluid-Structure Interaction with Known Movement of the Walls: Simulation of an Aortic Valve

Autores: Leonardo Geronzi, Emanuele Gasparotti, Katia Capellini, Ubaldo Cella, Corrado Groth, Stefano Porziani, Andrea Chiappa, Simona Celi, Marco Evangelos Biancolini
Publicado en: Lecture Notes in Computer Science, Computational Science – ICCS 2020, 2024, Página(s) 280-293
Editor: Springer International Publishing
DOI: 10.1007/978-3-030-50433-5_22

Peer reviewed articles (30)

The Hemodynamic Effect of Modified Blalock–Taussig Shunt Morphologies: A Computational Analysis Based on Reduced Order Modeling

Autores: Eirini Kardampiki; Emanuele Vignali; Dorela Haxhiademi; Duccio Federici; Edoardo Ferrante; Stefano Porziani; Andrea Chiappa; Corrado Groth; Margherita Cioffi; Marco Evangelos Biancolini; Emiliano Costa; Simona Celi
Publicado en: Electronics; Volume 11; Edición 13; Pages: 1930, Edición 5, 2022, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/electronics11131930

Fast interactive CFD evaluation of hemodynamics assisted by RBF mesh morphing and reduced order models: the case of aTAA modelling

Autores: Marco Evangelos Biancolini; Katia Capellini; Emiliano Costa; Corrado Groth; Simona Celi
Publicado en: International Journal on Interactive Design and Manufacturing (IJIDeM), Edición 14, 2020, Página(s) 1227–1238, ISSN 1955-2513
Editor: Springer Verlag
DOI: 10.1007/s12008-020-00694-5

Fabrication of Compliant and Transparent Hollow Cerebral Vascular Phantoms for In Vitro Studies Using 3D Printing and Spin–Dip Coating

Autores: Beatrice Bisighini, Pierluigi Di Giovanni Alba Scerrati ,Federica Trovalusci and Silvia Vesco
Publicado en: Materials 2023, 16(1), 166, 2023, ISSN 1996-1944
Editor: MDPI Open Access Publishing
DOI: 10.3390/ma16010166

Segmentation of the aorta in systolic phase from 4D flow MRI: multi-atlas vs. deep learning

Autores: Diana M Marin-Castrillon Leonardo Geronzi Arnaud Boucher Siyu Lin Marie-Catherine Morgant Alexandre Cochet Michel Rochette Sarah Leclerc Khalid Ambarki Ning Jin Ludwig Serge Aho Glele Alain Lalande Olivier Bouchot Benoît Presles
Publicado en: MAGMA . 2023 Oct;36(5):687-700, 2023, ISSN 0968-5243
Editor: Springer Verlag
DOI: 10.1007/s10334-023-01066-2

Machine learning and reduced order modelling for the simulation of braided stent deployment

Autores: Beatrice Bisighini; Beatrice Bisighini; Beatrice Bisighini; Miquel Aguirre; Miquel Aguirre; Miquel Aguirre; Marco Evangelos Biancolini; Federica Trovalusci; David Perrin; Stéphane Avril; Baptiste Pierrat
Publicado en: Frontiers in Physiology, Vol 14 (2023), Edición 1, 2023, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1148540

Calibration of the Mechanical Boundary Conditions for a Patient-Specific Thoracic Aorta Model Including the Heart Motion Effect

Autores: Leonardo Geronzi, Aline Bel-Brunon, Antonio Martinez, Michel Rochette, Marco Sensale, Olivier Bouchot, Alain Lalande, Siyu Lin, Pier Paolo Valentini, Marco Evangelos Biancolini
Publicado en: IEEE Trans Biomed Eng . 2023 Nov;70(11):3248-3259., 2023, ISSN 0018-9294
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2023.3287680

Computational Comparison of the Mechanical Behavior of Aortic Stent-Grafts Derived from Auxetic Unit Cells

Autores: Rahul Vellaparambil; Woo-Suck Han; Pierluigi Di Giovanni; Stéphane Avril
Publicado en: Cardiovascular Engineering and Technology (2024) 15:199–210, Edición 1, 2024, ISSN 1869-408X
Editor: Springer Pub. Co.,
DOI: 10.1007/s13239-023-00706-x

Aortic roadmapping during EVAR: a combined FEM–EM tracking feasibility study

Autores: Monica Emendi, Geir A. Tangen, Pierluigi Di Giovanni, Håvard Ulsaker, Reidar Brekken, Frode Manstad-Hulaas, Victorien Prot, Aline Bel-Brunon, Karen H. Støverud
Publicado en: International Journal of Computer Assisted Radiology and Surgery, Edición 19, 2024, Página(s) 2239-2247, ISSN 1861-6429
Editor: Springer
DOI: 10.1007/s11548-024-03187-y

Uncertainty Quantification in the In Vivo Image-Based Estimation of Local Elastic Properties of Vascular Walls

Autores: Benigno Marco Fanni; Maria Nicole Antonuccio; Alessandra Pizzuto; Sergio Berti; Giuseppe Santoro; Simona Celi
Publicado en: Journal of Cardiovascular Development and Disease; Volume 10; Edición 3; Pages: 109, Edición 1, 2023, ISSN 2078-2489
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcdd10030109

Patient-specific computational modelling of endovascular treatment for intracranial aneurysms”

Autores: Beatrice Bisighini, Miquel Aguirre, Baptiste Pierrat Stéphane Avril
Publicado en: Brain Multiphysics Volume 5, December 2023, 100079, 2023, ISSN 0346-251X
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.brain.2023.100079

Towards a reduced order model for EVAR planning and intra-operative navigation

Autores: Monica Emendi, Eirini Kardampiki, Karen-Helene Støverud, Antonio Martinez Pascual, Leonardo Geronzi, Sigrid Kaarstad Dahl, Victorien Prot, Paal Skjetne, Marco Evangelos Biancolini
Publicado en: Medical Engineering & Physics, Edición 131, 2024, Página(s) 104229, ISSN 1350-4533
Editor: Elsevier BV
DOI: 10.1016/j.medengphy.2024.104229

An image-based approach for the estimation of arterial local stiffness in vivo

Autores: Simona Celi; Emanuele Gasparotti; Katia Capellini; Francesco Bardi; Francesco Bardi; Martino Andrea Scarpolini; Martino Andrea Scarpolini; Carlo Cavaliere; Filippo Cademartiri; Emanuele Vignali
Publicado en: Frontiers in Bioengineering and Biotechnology, Vol 11 (2023), Edición 1, 2023, ISSN 2296-4185
Editor: Pubmed
DOI: 10.3389/fbioe.2023.1096196

Fast strain mapping in abdominal aortic aneurysm wall reveals heterogeneous patterns

Autores: Marta Irene Bracco; Marta Irene Bracco; Magdalena Broda; Ulver Spangsberg Lorenzen; Mateusz Cezary Florkow; Oudom Somphone; Stephane Avril; Marco Evangelos Biancolini; Laurence Rouet
Publicado en: Frontiers in Physiology, Vol 14 (2023), Edición 1, 2023, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1163204

Numerical simulation of aortic coarctations of different grades of severity: Flow features and importance of outlet boundary conditions

Autores: Mariotti A.; Antonuccio M. N.; Morello M.; Salvetti M. V.; Celi S.
Publicado en: Computers & Fluids Volume 266, 15 November 2023, 106043, Edición 1, 2023, ISSN 0346-251X
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compfluid.2023.106043

Enabling supra-aortic vessels inclusion in statistical shape models of the aorta: a novel non-rigid registration method

Autores: Martino Andrea Scarpolini,Marilena Mazzoli,Simona Celi
Publicado en: Front. Physiol., 10 August 2023 Sec. Computational Physiology and Medicine Volume 14 - 2023 |, 2023, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1211461

An RBF Meshless Approach to Evaluate Strain Due to Large Displacements in Flexible Printed Circuit Boards

Autores: Groth C.; Chiappa A.; Porziani S.; Salvini P.; Biancolini M. E.
Publicado en: Micromachines, Vol 13, Iss 8, p 1163 (2022), Edición 1, 2022, ISSN 2072-666X
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi13081163

Prediction of guidewire-induced aortic deformations during EVAR: a finite element and in vitro study

Autores: Monica Emendi; Monica Emendi; Karen H. Støverud; Geir A. Tangen; Håvard Ulsaker; Frode Manstad-H; Frode Manstad-H; Pierluigi Di Giovanni; Sigrid K. Dahl; Thomas Langø; Victorien Prot
Publicado en: Frontiers in Physiology, Vol 14 (2023), Edición 1, 2023, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1098867

Assessment of shape-based features ability to predict the ascending aortic aneurysm growth

Autores: Leonardo Geronzi; Leonardo Geronzi; Pascal Haigron; Antonio Martinez; Antonio Martinez; Kexin Yan; Kexin Yan; Michel Rochette; Aline Bel-Brunon; Jean Porterie; Siyu Lin; Siyu Lin; Diana Marcela Marin-Castrillon; Diana Marcela Marin-Castrillon; Alain Lalande; Alain Lalande; Olivier Bouchot; Morgan Daniel; Pierre Escrig; Jacques Tomasi; Pier Paolo Valentini; Marco Evangelos Biancolini
Publicado en: Frontiers in Physiology, Vol 14 (2023), Edición 1, 2023, ISSN 1664-042X
Editor: Frontiers Research Foundation
DOI: 10.3389/fphys.2023.1125931

A Hybrid Mock Circulatory Loop for Fluid Dynamic Characterization of 3D Anatomical Phantoms

Autores: Francesco Bardi; Emanuele Gasparotti; Emanuele Vignali; Stéphane Avril; Simona Celi
Publicado en: IEEE Transactions on Biomedical Engineering ( Volume: 70, Edición: 5, May 2023), 2023, ISSN 0018-9294
Editor: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tbme.2022.3224581

Computer-aided shape features extraction and regression models for predicting the ascending aortic aneurysm growth rate

Autores: Leonardo Geronzi a b, Antonio Martinez a b, Michel Rochette b, Kexin Yan b c, Aline Bel-Brunon c, Pascal Haigron d, Pierre Escrig d, Jacques Tomasi d, Morgan Daniel d, Alain Lalande e f, Siyu Lin e f, Diana Marcela Marin-Castrillon e f, Olivier Bouchot g, Jean Porterie h, Pier Paolo Valentini a, Marco Evangelos Biancolini a
Publicado en: Computers in Biology and Medicine Volume 162, August 2023, 107052, 2023, ISSN 0010-4825
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2023.107052

EndoBeams.jl: A Julia finite element package for beam-to-surface contact problems in cardiovascular mechanics

Autores: Beatrice Bisighini; Miquel Aguirre; Baptiste Pierrat; David Perrin; Stéphane Avril
Publicado en: Advances in Engineering Software Volume 171, September 2022, 103173, Edición 1, 2022, ISSN 0965-9978
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.advengsoft.2022.103173

Ultrasound Probe Pressure Affects Aortic Wall Stiffness: A Patient-Specific Computational Study in Abdominal Aortic Aneurysms

Autores: Marta Irene Bracco, Ali Akbar Karkhaneh Yousefi, Laurence Rouet, Stéphane Avril
Publicado en: Annals of Biomedical Engineering, Edición 53, 2025, Página(s) 71-82, ISSN 0090-6964
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10439-024-03608-8

Coupling synthetic and real-world data for a deep learning-based segmentation process of 4D flow MRI

Autores: Simone Garzia; Martino Andrea Scarpolini; Marilena Mazzoli; Katia Capellini; Angelo Monteleone; Filippo Cademartiri; Vincenzo Positano; Simona Celi
Publicado en: Computer Methods and Programs in Biomedicine Volume 242, December 2023, 107790, Edición 1, 2023, ISSN 0346-251X
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.cmpb.2023.107790

High fidelity fluid-structure interaction by radial basis functions mesh adaption of moving walls: A workflow applied to an aortic valve

Autores: Leonardo Geronzi, Emanuele Gasparotti, Katia Capellini, Ubaldo Cella, Corrado Groth, Stefano Porziani, Andrea Chiappa, Simona Celi, Marco Evangelos Biancolini
Publicado en: Journal of Computational Science, Edición Volume 51, 2021, ISSN 1877-7503
Editor: Elsevier BV
DOI: 10.1016/j.jocs.2021.101327

Experimental validation of auxetic stent designs: three-point bending of 3D printed Titanium prototypes

Autores: Rahul Vellaparambil,Woo-Suck Han Pierluigi Di Giovanni Stéphane Avril
Publicado en: Front. Med. Technol., 06 May 2024 Sec. Cardiovascular Medtech Volume 6 - 2024 |, 2024, ISSN 2673-3129
Editor: Frontiers in Medical Technology
DOI: 10.3389/fmedt.2024.1388207

Fabrication of deformable patient-specific AAA models by material casting techniques

Autores: Maria Nicole Antonuccio Emanuele Gasparotti , Francesco Bardi Angelo Monteleone , Alexandre This Laurence Rouet Stéphane Avril , Simona Celi
Publicado en: Front Cardiovasc Med . 2023 Sep 11:10:1141623., 2023, ISSN 2813-5911
Editor: Lausanne: Frontiers Media S.A.
DOI: 10.3389/fcvm.2023.1141623

A novel formulation for the study of the ascending aortic fluid dynamics with in vivo data

Autores: Katia Capellini, Emanuele Gasparotti, Ubaldo Cella, Emiliano Costa, Benigno Marco Fanni, Corrado Groth, Stefano Porziani, Marco Evangelos Biancolini, Simona Celi
Publicado en: Medical Engineering & Physics, Edición Volume 91, 2021, Página(s) 68-78, ISSN 1350-4533
Editor: Elsevier BV
DOI: 10.1016/j.medengphy.2020.09.005

Potential of Auxetic Designs in Endovascular Aortic Repair: A Computational Study of Their Mechanical Performance

Autores: Rahul Vellaparambil; Woo-Suck Han; Pierluigi Di Giovanni; Stéphane Avril
Publicado en: Journal of the Mechanical Behavior of Biomedical Materials, Edición 1, 2023, ISSN 1751-6161
Editor: Elsevier BV
DOI: 10.2139/ssrn.4258753

HPC+ in the medical field: Overview and current examples

Autores: Koch, Miriam; Arlandini, Claudio; Antonopoulos, Gregory; Baretta, Alessia; Beaujean, Pierre; BEX, Geert Jan; Biancolini, Marco Evangelos; Celi, Simona; Costa, Emiliano; Drescher, Lukas; Eleftheriadis, Vasileios; Fadel, Nur A.; Fink, Andreas; Galbiati, Federica; Hatzakis, Ilias; Hompis, Georgios; Lewandowski, Natalie; Memmolo, Antonio; Mensch, Carl; Obrist, Dominik; Paneta, Valentina; Papadimitroul
Publicado en: Technology and Health Care 31 (2023) 1509–1523, Edición 2, 2023, ISSN 0928-7329
Editor: IOS Press
DOI: 10.3233/thc-229015

Towards the 2D velocity reconstruction in abdominal aorta from Color-Doppler Ultrasound

Autores: Maria Nicole Antonuccio; Hernan G. Morales; Alexandre This; Katia Capellini; Stéphane Avril; Simona Celi; Laurence Rouet
Publicado en: Medical Engineering & Physics Volume 107, September 2022, 103873, Edición 1, 2022, ISSN 1350-4533
Editor: Elsevier BV
DOI: 10.1016/j.medengphy.2022.103873

Other (3)

Aortic Wall Stiffness Depends on Ultrasound Probe Pressure

Autores: Bracco, Marta, Irene; Eiberg, Jonas, Peter; Lorenzen, Ulver, Spangsberg; Avril, Stephane; Rouet, Laurence
Publicado en: Medical Physics (physics.med-ph) arXiv:2312.07980 [physics.med-ph], Edición 1, 2023
Editor: Medical Physics
DOI: 10.48550/arxiv.2312.07980

Impact of the Spatial Velocity Inlet Distribution on the Hemodynamics of the Thoracic Aorta

Autores: Mariotti A.; Celi S.; Antonuccio M. N.; Salvetti M. V.
Publicado en: Cardiovascular Engineering and Technology,2023 Oct;14(5):713-725., Edición 1, 2023, ISSN 1539-3704
Editor: Pubmed
DOI: 10.1007/s13239-023-00682-2

Effect of turbulence and viscosity models on wall shear stress derived biomarkers for aorta simulations

Autores: Martínez A.; Hoeijmakers M.; Geronzi L.; Morgenthaler V.; Tomasi J.; Rochette M.; Biancolini M. E.
Publicado en: "Computers in Biology and Medicine, 2023, Computers in Biology and Medicine, 167, pp.107603. ⟨10.1016/j.compbiomed.2023.107603⟩", Edición 1, 2023
Editor: https://hal.science/
DOI: 10.1016/j.compbiomed.2023.107603

Derechos de propiedad intelectual

Patent (3)

METHOD FOR SIMULATING A DEVICE DEPLOYMENT

Número de solicitud/publicación: 22 305140
Fecha: 2022-02-09
Solicitante(s): PREDISURGE

METHOD FOR SIMULATING A DEVICE DEPLOYMENT

Número de solicitud/publicación: 22 305140
Fecha: 2022-02-09
Solicitante(s): ASSOCIATION POUR LA RECHERCHE ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS

AORTIC ABDOMINAL ANEURYSM BIOMARKERS

Número de solicitud/publicación: 21 290095
Fecha: 2021-12-21
Solicitante(s): PHILIPS FRANCE