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The life cycle of extracellular vesicles in prostate cancer: from biogenesis and homing, to functional relevance

Project description

Profiling the messengers that cancer cells use to spread more than their word

In recent years, extracellular vesicles (EVs) have risen from relative obscurity to stardom. They are secreted by all cells and are now recognised as the carriers of biologically active molecules that travel to local or distant targets to mediate cell-cell communication. Cancer progression and metastasis is linked to EVs as these cells use EVs to export regulatory molecules like oncoproteins and oncopeptides. Further, EVs are found in bodily fluids, supporting their potential as blood-based or urine-based biomarkers as well as targets for cancer therapies. proEVLifeCycle is creating a dynamic team of researchers to enhance understanding of the lifecycle of EVs involved in prostate cancer to improve diagnosis and treatment of the most common cancer in men.

Call for proposal

H2020-MSCA-ITN-2019
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Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Netherlands
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 265 619,88

Participants (9)

CARDIFF UNIVERSITY
United Kingdom
EU contribution
€ 303 172,56
Address
Newport Road 30-36
CF24 ODE Cardiff
Activity type
Higher or Secondary Education Establishments
TURUN YLIOPISTO
Finland
EU contribution
€ 280 805,76
Address
Yliopistonmaki
20014 Turku
Activity type
Higher or Secondary Education Establishments
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
EU contribution
€ 264 207,24
Address
Giefinggasse 4
1210 Wien
Activity type
Research Organisations
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS
Spain
EU contribution
€ 250 904,88
Address
Parque Tecnologico Edificio 801 A
48160 Derio Vizcaya
Activity type
Research Organisations
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
EU contribution
€ 274 802,04
Address
Rue De Tolbiac 101
75654 Paris
Activity type
Research Organisations
FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III
Spain
EU contribution
€ 250 904,88
Address
C Melchor Fernandez Almagro 3
28029 Madrid
Activity type
Research Organisations
GenomeScan B.V.
Netherlands
EU contribution
€ 265 619,88
Address
Plesmanlaan 1D
2333 BZ Leiden
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
ANAXOMICS BIOTECH SL
Spain
EU contribution
€ 250 904,88
Address
Calle Diputacio 237, P 1 Pta 1
08007 Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
EU contribution
€ 265 619,88
Address
Heidelberglaan 100
3584 CX Utrecht
Activity type
Higher or Secondary Education Establishments