Profiling the messengers that cancer cells use to spread more than their word
In recent years, extracellular vesicles (EVs) have risen from relative obscurity to stardom. They are secreted by all cells and are now recognised as the carriers of biologically active molecules that travel to local or distant targets to mediate cell-cell communication. Cancer progression and metastasis is linked to EVs as these cells use EVs to export regulatory molecules like oncoproteins and oncopeptides. Further, EVs are found in bodily fluids, supporting their potential as blood-based or urine-based biomarkers as well as targets for cancer therapies. proEVLifeCycle is creating a dynamic team of researchers to enhance understanding of the lifecycle of EVs involved in prostate cancer to improve diagnosis and treatment of the most common cancer in men.
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