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The life cycle of extracellular vesicles in prostate cancer: from biogenesis and homing, to functional relevance

Project description

Profiling the messengers that cancer cells use to spread more than their word

In recent years, extracellular vesicles (EVs) have risen from relative obscurity to stardom. They are secreted by all cells and are now recognised as the carriers of biologically active molecules that travel to local or distant targets to mediate cell-cell communication. Cancer progression and metastasis is linked to EVs as these cells use EVs to export regulatory molecules like oncoproteins and oncopeptides. Further, EVs are found in bodily fluids, supporting their potential as blood-based or urine-based biomarkers as well as targets for cancer therapies. proEVLifeCycle is creating a dynamic team of researchers to enhance understanding of the lifecycle of EVs involved in prostate cancer to improve diagnosis and treatment of the most common cancer in men.

Coordinator

ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Net EU contribution
€ 265 619,88
Address
Dr Molewaterplein 40
3015 GD Rotterdam
Netherlands

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Region
West-Nederland Zuid-Holland Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (9)

CARDIFF UNIVERSITY
United Kingdom
Net EU contribution
€ 303 172,56
Address
Newport Road 30 36
CF24 0DE Cardiff

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Region
Wales East Wales Cardiff and Vale of Glamorgan
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
TURUN YLIOPISTO
Finland
Net EU contribution
€ 280 805,76
Address
Yliopistonmaki
20014 Turku

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Region
Manner-Suomi Etelä-Suomi Varsinais-Suomi
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
AIT AUSTRIAN INSTITUTE OF TECHNOLOGY GMBH
Austria
Net EU contribution
€ 264 207,24
Other funding
€ 0,00
ASOCIACION CENTRO DE INVESTIGACION COOPERATIVA EN BIOCIENCIAS
Spain
Net EU contribution
€ 250 904,88
Address
Parque Tecnologico Edificio 801 A
48160 Derio Vizcaya

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Region
Noreste País Vasco Bizkaia
Activity type
Research Organisations
Other funding
€ 0,00
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 274 802,04
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
FUNDACION SECTOR PUBLICO ESTATAL CENTRO NACIONAL INVESTIGACIONES ONCOLOGICAS CARLOS III
Spain
Net EU contribution
€ 250 904,88
Address
C Melchor Fernandez Almagro 3
28029 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Other funding
€ 0,00
GenomeScan B.V.
Netherlands
Net EU contribution
€ 265 619,88
Address
Plesmanlaan 1d
2333 BZ Leiden

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
ANAXOMICS BIOTECH SL
Spain
Net EU contribution
€ 250 904,88
Address
Calle Diputacio 237, P 1 Pta 1
08007 Barcelona

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Este Cataluña Barcelona
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 265 619,88
Address
Heidelberglaan 100
3584 CX Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00