CORDIS provides links to public deliverables and publications of HORIZON projects.
Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .
Deliverables
A final international conference with all PIs and PhDs is organized
Time lapse movies of protons crossing the membrane and spreading on the receiving interfaceExperiments in the presence of a transmembrane proton gradient are performed and time driven changes of the proton concentration are imaged
PROTON vacancies publishedThe PhD positions are advertised
Websites (external and internal)A website for the proton consortium is designed and mounted
Scientific coursesTraining schools providing scientific courses will be conducted
Time lapse movies of traveling proton fronts along the hydration shells of lipid bilayersTimedependent changes of proton concentration gradients on top of a lipid bilayer are imaged
Transferable skill coursesTraining schools providing transferable skills courses will be conducted
Overall recruitmentRecruitment of 15 ESRs and their enrolment in a Doctoral Program
Personal data and data related to the project allowances of the recruited PhD students are declared
Cysteine-labelled, pH-responsive HpUreI fluorescenceFunctional investigations are performed to obtain insight into the gating mechanism of HpUreI
Model of FNT substrate-proton co-transportThe results of in vitro and in silico investigations of solute and proton cotransport are merged into a model
Catalogue of suitable combinations of titratable lipid residues and amino acid side chains for proton transfer from the interface into the pore of the transporterThe lipid dependence of proton transfer from the membrane surface into the membrane transporter is investigated
Ranking of different surface structures/intraluminal transporter structures according to their ability to conduct protonsWe measure proton fluxes along different surfaces in vitro and in silico and compare the specific conductances
15 Doctoral theses submittedThe ESRs summarize their results in PhD theses
Inhibitors for artificial proton channelsSmall molecules that are capable of inhibiting facilitated proton conductance are identified
Mechanistic model for ions (protons) moving in the hydration layers of collagenThe results of in vitro and in silico measurements of proton conductance along collagen are summarized by a model
Comprehensive Education Program ReportThe effectiveness of the training program will be reported at the end of the project, to be used as a reference for structuring future multidisciplinary training programs.
Model of pH-dependent conformational changes during GPR68 signallingInsight into the mechanism of pH sensing is obtained
Publications
Author(s):
Ana-Nicoleta Bondar; Mihail Barboiu
Published in:
Crossref, Issue 1, 2023, ISSN 0005-2736
Publisher:
Elsevier BV
DOI:
10.1016/j.bbamem.2023.184139
Author(s):
Bingxin Chu; Arianna Marchioro; Sylvie Roke
Published in:
Crossref, Issue 5, 2023, ISSN 0021-9606
Publisher:
American Institute of Physics
DOI:
10.1063/5.0135157
Author(s):
Seonwoo Lee, David Roesel, Sylvie Roke
Published in:
The Journal of Chemical Physics, Issue 155/18, 2021, Page(s) 184704, ISSN 0021-9606
Publisher:
American Institute of Physics
DOI:
10.1063/5.0063362
Author(s):
Danila Boytsov; Stefania Brescia; Gustavo Chaves; Sabina Koefler; Christof Hannesschlaeger; Christine Siligan; Nikolaus Gössweiner-Mohr; Boris Musset; Peter Pohl
Published in:
Crossref, Issue 10, 2023, ISSN 1613-6810
Publisher:
Wiley - V C H Verlag GmbbH & Co.
DOI:
10.1101/2022.05.09.491141
Author(s):
Iga Jakobowska, Frank Becker, Stefano Minguzzi, Kerrin Hansen, Björn Henke, Nathan Hugo Epalle, Eric Beitz, Stefan Hannus
Published in:
Pharmaceuticals, Issue 14/8, 2021, Page(s) 757, ISSN 1424-8247
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ph14080757
Author(s):
Ana-Nicoleta Bondar
Published in:
Frontiers in Chemistry, Vol 9 (2021), Issue 1, 2021, ISSN 2296-2646
Publisher:
frontiers in chemistry
DOI:
10.3389/fchem.2021.685761
Author(s):
Andrei I-M, Barboiu M.
Published in:
Biomolecules, Issue 2218273X, 2022, Page(s) 1473, ISSN 2218-273X
Publisher:
MDPI
DOI:
10.3390/biom12101473
Author(s):
Denis G. Knyazev; Todd P. Silverstein; Stefania Brescia; Anna Maznichenko; Peter Pohl
Published in:
Biomolecules, Vol 13, Iss 11, p 1641 (2023), Issue 8, 2023, ISSN 2218-273X
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.2139/ssrn.4508746
Author(s):
Anna-Lena Köpnick, Annika Jansen, Katharina Geistlinger, Nathan Hugo Epalle, Eric Beitz
Published in:
PLOS ONE, Issue 16/3, 2021, Page(s) e0249110, ISSN 1932-6203
Publisher:
Public Library of Science
DOI:
10.1371/journal.pone.0249110
Author(s):
Epalle, N. H.
Beitz, E.
Published in:
Biomolecules, 2022, ISSN 2218-273x
Publisher:
MDPI
DOI:
10.3390/biom12121794
Author(s):
Bingxin Chu, Denys Biriukov, Marie Bischoff, Milan Předota, Sylvie Roke, Arianna Marchioro
Published in:
Faraday Discussions, Issue 246, 2024, Page(s) 407-425, ISSN 1359-6640
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d3fd00036b
Author(s):
Jain, Honey; Karathanou, Konstantina; Bondar, Ana-Nicoleta
Published in:
Biomolecules 13(8), 1238 - (2023). doi:10.3390/biom13081238, Issue 6, 2023, ISSN 2218-273X
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/biom13081238
Author(s):
Franziska Ragaller, Luca Andronico, Jan Sykora, Waldemar Kulig, Tomasz Rog†, Yagmur Balim Urem, Abhinav, Dmytro I. Danylchuk, Martin Hof, Andrey Klymchenko, Mariana Amaro, Ilpo Vattulainen and Erdinc Sezgin
Published in:
Open Biology, 2022, ISSN 2046-2441
Publisher:
Royal Society Publishing
DOI:
10.1098/rsob.220175
Author(s):
Biswal, Satyaranjan
Agmon, Noam
Published in:
Biomolecules, 2023, ISSN 2218-273X
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/biom13121744
Author(s):
Jürgen Kreiter; Tatyana Tyschuk; Elena E Pohl
Published in:
Biomolecules, Vol 14, Iss 1, p 21 (2023), Issue 7, 2024, ISSN 2218-273X
Publisher:
MDPI
DOI:
10.3390/biom14010021
Author(s):
Ana-Nicoleta Bondar; Ana-Nicoleta Bondar; Mercedes Alfonso-Prieto
Published in:
Frontiers in physics 10, 963716 (2022). doi:10.3389/fphy.2022.963716, Issue 5, 2022, ISSN 2296-424X
Publisher:
Frontiers in Physics
DOI:
10.3389/fphy.2022.963716
Author(s):
Bingxin Chu, Sylvie Roke, Arianna Marchioro
Published in:
The Journal of Chemical Physics, Issue 160, 2024, ISSN 0021-9606
Publisher:
American Institute of Physics
DOI:
10.1063/5.0198247
Author(s):
Lee, Seonwoo
Poojari, Chetan S.
Maznichenko, Anna
Roesel, David
Swiderska, Iwona
Pohl, Peter
Hub, Jochen S.
Roke, Sylvie
Published in:
Journal of the American Chemical Society, 2024, ISSN 0002-7863
Publisher:
American Chemical Society
DOI:
10.1021/jacs.4c02810
Author(s):
Abhinav, Jurkiewicz P, Hof M, Allolio C, Sýkora J.
Published in:
Biomolecules, 2022, ISSN 2218-273X
Publisher:
mdpi
DOI:
10.3390/biom12121894
Author(s):
Cornelius Nerlich, Nathan H. Epalle, Philip Seick, Eric Beitz
Published in:
Pharmaceuticals, Issue 14/11, 2021, Page(s) 1191, ISSN 1424-8247
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ph14111191
Author(s):
Erol Licsandru; Iuliana-Marilena Andrei; Arie van der Lee; Mihail Barboiu
Published in:
https://hal.archives-ouvertes.fr/hal-03410221, Issue 4, 2021, ISSN 2296-2646
Publisher:
Front Chem
DOI:
10.3389/fchem.2021.678962
Author(s):
Anna-Lena Köpnick; Katharina Geistlinger; Eric Beitz
Published in:
The FEBS Journal, Issue 2, 2021, ISSN 1742-464X
Publisher:
Blackwell Publishing Inc.
DOI:
10.1111/febs.16024
Author(s):
Katharina Geistlinger; Jana D. R. Schmidt; Eric Beitz
Published in:
Life; Volume 12; Issue 1; Pages: 120, Issue 2, 2022, ISSN 2075-1729
Publisher:
life
DOI:
10.3390/life12010120
Author(s):
Iuliana M. Andrei; Arnaud Chaix; Belkacem Tarek Benkhaled; Romain Dupuis; Chaimaa Gomri; Eddy Petit; Maurizio Polentarutti; Arie van der Lee; Mona Semsarilar; Mihail Barboiu
Published in:
Journal of the American Chemical Society, Issue 3, 2023, ISSN 0002-7863
Publisher:
American Chemical Society
DOI:
10.1021/jacs.3c02815
Author(s):
Iuliana M. Andrei, Wenzhang Chen, Marc Baaden, Stéphane P. Vincent, Mihail Barboiu
Published in:
Journal of the American Chemical Society, Issue 145, 2023, Page(s) 21904-21914, ISSN 0002-7863
Publisher:
American Chemical Society
DOI:
10.1021/jacs.3c06335
Author(s):
Kristina Žuna, Olga Jovanović, Ljudmila S Khailova, Sanja Škulj , Zlatko Brkljača , Jürgen Kreiter, Elena A Kotova , Mario Vazdar , Yuri N Antonenko, Elena E Pohl
Published in:
Biomolecules, Issue 11/8, 2021, Page(s) 1178, ISSN 2218-273X
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/biom11081178
Author(s):
Katharina Geistlinger; Jana D R Schmidt; Eric Beitz
Published in:
Crossref, Issue 1, 2023, ISSN 2752-6542
Publisher:
PMC
DOI:
10.1093/pnasnexus/pgad007
Author(s):
Iuliana‐Marilena Andrei; Dmytro Strilets; Shixin Fa; Marc Baaden; Tomoki Ogoshi; Mihail Barboiu
Published in:
https://hal.science/hal-04257786, Issue 1, 2023, ISSN 1433-7851
Publisher:
John Wiley & Sons Ltd.
DOI:
10.1002/anie.202310812
Author(s):
Wouter van Bergen, Kristina Žuna, Jan Fiala, Elena E. Pohl, Albert J.R. Heck, Marc P. Baggelaar
Published in:
ACS Chemical Biology, Issue 19, 2024, Page(s) 1705-1718, ISSN 1554-8929
Publisher:
American Chemical Society
DOI:
10.1021/acschembio.3c00637
Author(s):
D. Roesel; M. Eremchev; T. Schönfeldová; S. Lee; S. Roke
Published in:
Appl. Phys. Lett., Issue 12, 2022, ISSN 0003-6951
Publisher:
American Institute of Physics
DOI:
10.1063/5.0085807
Author(s):
Jana D.R. Schmidt, Eric Beitz
Published in:
Journal of Biological Chemistry, Issue 298, 2022, Page(s) 101513, ISSN 0021-9258
Publisher:
American Society for Biochemistry and Molecular Biology Inc.
DOI:
10.1016/j.jbc.2021.101513
Author(s):
Kapur, B.; Baldessari, F.; Lazaratos, M.; Nar, H.; Schnapp, G.; Giorgetti, A.; Bondar, A.-N.
Published in:
Computational and Structural Biotechnology Journal, Issue 21, 2023, Page(s) 4370-4384, ISSN 2001-0370
Publisher:
Elsevier
DOI:
10.1016/j.csbj.2023.08.034
Author(s):
Ana-Nicoleta Bondar
Published in:
Crossref, Issue 3, 2022, ISSN 1876-1623
Publisher:
Adv Protein Chem Struct Biol
DOI:
10.1016/bs.apcsb.2021.09.002
Author(s):
Sykora, J., Prokop, Z., Damborsky, J., Abhinav, Hof, M., Amaro, M.
Published in:
Springer Series on Fluorescence, 2023
Publisher:
Springer
DOI:
10.1007/4243_2022_40
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