Innovative Training Network on PER and polyfluorinated alkyl substances towards the Future Of Research and its Communication in Europe 3

Información del proyecto

PERFORCE3

Identificador del acuerdo de subvención: 860665

DOI

10.3030/860665

Proyecto cerrado

Fecha de la firma de la CE 9 Agosto 2019

Fecha de inicio 1 Enero 2020

Fecha de finalización 30 Junio 2024

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 4 160 995,92

Aportación de la UE

€ 4 160 995,92

Coordinado por

STOCKHOLMS UNIVERSITET
Sweden

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Other (5)

Open translational research dissemination workshop

Open translational research dissemination workshop (M45)

Delivery of online seminars (webinars) I-VIII

Delivery of online seminars (webinars) I-VIII(Multiple due dates: M11, M14, M17, M20, M23, M26, M29, M32)

Blog/social media posts
Advertisement of ESR positions
Nobel Laureate Lectures

Nobel Laureate Lectures(Multiple due dates: M12 and M36)

Websites, patent fillings, videos etc. (2)

PERFORCE3 Website operational for external communications
Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III

Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III(Multiple due dates: M10, M22 and M34)

Documents, reports (5)

Fellow-only meetings I-IV

Fellow-only meetings I-IV(Multiple due dates: M10, M22, M34 and M46)

Development of a multi-matrix total organofluorine technique

Development of a multimatrix total organofluorine technique

Preliminary results from near-field air exposure, dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Preliminary results from nearfield air exposure dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Development of a multi-matrix total oxidisable precursors technique

Development of a multimatrix total oxidisable precursors technique

Report on degradation experiments on alternative precursor PFASs

Open Research Data Pilot (1)

Provide exposure and effect results to established research data repositories, regulatory institutes and authorities

Publicaciones

Peer reviewed articles (43)

Occurrence, Fate, and Related Health Risks of PFAS in Raw and Produced Drinking Water

Autores: Mohammad Sadia, Ingeborg Nollen, Rick Helmus, Thomas L. ter Laak, Frederic Béen, Antonia Praetorius, Annemarie P. van Wezel
Publicado en: Environmental Science & Technology, Edición 57(8), 2023, Página(s) 062–3074, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.2c06015

A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry

Autores: Mohammad Sadia, Youssef Boudguiyer, Rick Helmus, Marianne Seijo, Antonia Praetorius, Saer Samanipour
Publicado en: Analytical and Bioanalytical Chemistry, 2024, ISSN 1618-2642
Editor: Springer Verlag
DOI: 10.1007/s00216-024-05425-3

Influence of grain size, organic carbon and organic matter residue content on the sorption of per- and polyfluoroalkyl substances in aqueous film forming foam contaminated soils - Implications for remediation using soil washing

Autores: Michel Hubert, Hans Peter H. Arp, Mona Cecilie Hansen, Gabriela Castro, Thomas Meyn, Alexandros G. Asimakopoulos, Sarah E. Hale
Publicado en: Science of The Total Environment, Edición 875, 2023, Página(s) 162668, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162668

The Need to Include a Fluorine Mass Balance in the Development of Effective Technologies for PFAS Destruction

Autores: Sanne J. Smith, Mélanie Lauria, Christopher P. Higgins, Kurt D. Pennell, Jens Blotevogel, Hans Peter H. Arp
Publicado en: Environmental Science & Technology, Edición 58, 2024, Página(s) 2587-2590, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.3c10617

Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate

Autores: Sanne J. Smith, Karin Wiberg, Philip McCleaf, Lutz Ahrens
Publicado en: ACS ES&T Water, Edición 2(5), 2022, Página(s) 841-851, ISSN 2690-0637
Editor: American Chemical Society
DOI: 10.1021/acsestwater.2c00032

Are Hazard Assessment Methods in the Assessment of Chemical Alternatives Suitable for REACH?

Autores: Rachel L. London, Juliane Glüge, Martin Scheringer
Publicado en: Environmental Science & Technology, Edición 58, 2024, Página(s) 18811-18821, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c03979

Total oxidizable precursors assay for PFAS in human serum

Autores: Lara Cioni, Vladimir Nikiforov, Ana Carolina M. F. Coelho, Torkjel M. Sandanger, Dorte Herzke
Publicado en: Environment International, Edición 170, 2022, Página(s) 107656, ISSN 0160-4120
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107656

Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants

Autores: Viktória Licul-Kucera, Tobias Frömel, Martin Kruså, Annemarie P. van Wezel, Thomas P. Knepper
Publicado en: Chemosphere, Edición 339, 2023, Página(s) 139563, ISSN 0045-6535
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.139563

Legacy perfluoroalkyl acids and their oxidizable precursors in plasma samples of Norwegian women

Autores: Ana Carolina M. F. Coêlho, Lara Cioni, Wendy Van Dreunen, Vivian Berg, Charlotta Rylander, Ilona Urbarova, Dorte Herzke, Torkjel M. Sandanger
Publicado en: Environment International, Edición 178, 2023, Página(s) 108026, ISSN 1873-6750
Editor: Elsevier
DOI: 10.1016/j.envint.2023.108026

Sorption of per- and poly-fluoroalkyl substances and their precursors on activated carbon under realistic drinking water conditions: Insights into sorbent variability and PFAS structural effects

Autores: Mohammad Sadia, Lola Beltrán Beut, Marko Pranić, Annemarie P. van Wezel, Thomas L. ter Laak
Publicado en: Heliyon, Edición 10(3), 2024, Página(s)  e25130, ISSN 2405-8440
Editor: Elsevier
DOI: 10.1016/j.heliyon.2024.e25130

Electrochemical Oxidation for Treatment of PFAS in Contaminated Water and Fractionated Foam ─ A Pilot-Scale Study

Autores: Sanne J. Smith, Melanie Lauria, Lutz Ahrens, Philip McCleaf, Patrik Hollman, Sofia Bjälkefur Seroka, Timo Hamers, Hans Peter H. Arp, Karin Wiberg
Publicado en: ACS EST Water, Edición 3(4), 2023, Página(s) 1201–1211, ISSN 2690-0637
Editor: American Chemical Society
DOI: 10.1021/acsestwater.2c00660

Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells

Autores: Lackson Kashobwe, Faezeh Sadrabadi, Lars Brunken, Ana Carolina M.F. Coelho, Torkjel M. Sandanger, Albert Braeuning, Thorsten Buhrke, Mattias Öberg, Timo Hamers, Pim.E.G. Leonards
Publicado en: Toxicology, Edición 506, 2024, Página(s) 153862, ISSN 0300-483X
Editor: Elsevier BV
DOI: 10.1016/j.tox.2024.153862

Multiple-Criteria Decision Analysis for Assessments of Chemical Alternatives (MCDA-ACA)

Autores: Rachel L. London, Juliane Glüge, Martin Scheringer
Publicado en: Environmental Science & Technology, Edición 58, 2024, Página(s) 19315-19324, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c03980

In vitro screening of understudied PFAS with a focus on lipid metabolism disruption

Autores: Lackson Kashobwe, Faezeh Sadrabadi, Albert Braeuning, Pim E. G. Leonards, Thorsten Buhrke, Timo Hamers
Publicado en: Archives of Toxicology, Edición 98, 2024, Página(s) 3381–3395, ISSN 0340-5761
Editor: Springer Verlag
DOI: 10.1007/s00204-024-03814-2

Information Requirements under the Essential-Use Concept: PFAS Case Studies.

Autores: Juliane Glüge; Rachel London; Ian T. Cousins; Jamie C. DeWitt; Gretta Goldenman; Dorte Herzke; Rainer Lohmann; Mark A. Miller; Carla A. Ng; Sharyle Patton; Xenia Trier; Zhanyun Wang; Martin Scheringer; Martin Scheringer
Publicado en: Environmental Science & Technology, 2021, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.1c03732

Per- and polyfluoroalkyl substances (PFAS) in white-tailed sea eagle eggs from Sweden: temporal trends (1969–2021), spatial variations, fluorine mass balance, and suspect screening

Autores: Faiz Haque, Anne L. Soerensen, Martin Sköld, Raed Awad, Kyra M. Spaan, Mélanie Z. Lauria, Merle M. Plassmann, Jonathan P. Benskin
Publicado en: Environmental Science: Processes & Impacts, Edición 25, 2023, Página(s) 1549-1563, ISSN 2050-7895
Editor: Royal Society of Chemistry 
DOI: 10.1039/d3em00141e

Shellfish and shorebirds from the East-Asian Australian flyway as bioindicators for unknown per- and polyfluoroalkyl substances using the total oxidizable precursor assay

Autores: Junjie Zhang, Lara Cioni, Veerle L.B. Jaspers, Alexandros G. Asimakopoulos, He-Bo Peng, Tobias A. Ross, Marcel Klaassen, Dorte Herzke
Publicado en: Journal of Hazardous Materials, Edición 487, 2025, Página(s) 137189, ISSN 0304-3894
Editor: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.137189

Closing the Organofluorine Mass Balance in Marine Mammals Using Suspect Screening and Machine Learning-Based Quantification

Autores: Mélanie Z. Lauria, Helen Sepman, Thomas Ledbetter, Merle Plassmann, Anna M. Roos, Malene Simon, Jonathan P. Benskin, Anneli Kruve
Publicado en: Environmental Science & Technology, Edición 58, 2024, Página(s) 2458-2467, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.3c07220

A group of novel polyfluoroether substances affects lipid metabolism in human hepatocyte HepaRG cells less than classic perfluoroalkyl compounds

Autores: Faezeh Sadrabadi, Wiebke Alker, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Publicado en: Toxicology in Vitro, Edición 105, 2025, Página(s) 106024, ISSN 0887-2333
Editor: Elsevier BV
DOI: 10.1016/j.tiv.2025.106024

Perfluoro(2-ethoxy-2-fluoroethoxy)-acetic Acid and Other Target and Suspect PFAS in the Vicinity of a Fluoropolymer Production Plant

Autores: Joost Dalmijn, Jonathan P. Benskin, Matthew E. Salter, Andrew J. Sweetman, Crispin J. Halsall, Jack Garnett, Ian T. Cousins
Publicado en: Environmental Science & Technology, Edición 59(29), 2025, Página(s) 15420–15431, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.5c07856

An automated and high-throughput data processing workflow for PFAS identification in biota by direct infusion ultra-high resolution mass spectrometry

Autores: Silvia Dudášová, Johann Wurz, Urs Berger, Thorsten Reemtsma, Qiuguo Fu, Oliver J. Lechtenfeld
Publicado en: Analytical and Bioanalytical Chemistry, Edición 416, 2024, Página(s) 4833–4848, ISSN 1618-2642
Editor: Springer Verlag
DOI: 10.1007/s00216-024-05426-2

Emission inventory of PFASs and other fluorinated organic substances for the fluoropolymer production industry in Europe

Autores: Joost Dalmijn, Juliane Glüge, Martin Scheringer, Ian T. Cousins
Publicado en: Environmental Science: Processes & Impacts, Edición 26, 2024, Página(s) 269-287, ISSN 2050-7887
Editor: Royal Society of Chemistry
DOI: 10.1039/d3em00426k

Exploring Perfluoroalkyl and Polyfluoroalkyl Substance Presence and Potential Leaching from Reverse Osmosis Membranes: Implications for Drinking Water Treatment

Autores: Mohammad Sadia, Thomas L. ter Laak, Emile R. Cornelissen, Annemarie P. van Wezel
Publicado en: Environmental Science & Technology, Edición 58(35), 2024, Página(s) 15799–15806, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c04743

HFPO-DA and Other PFAS in Air Downwind of a Fluoropolymer Production Plant in the Netherlands: Measurements and Modeling

Autores: Joost Dalmijn, Julia J. Shafer, Jonathan P. Benskin, Matthew E. Salter, Jana H. Johansson, Ian T. Cousins
Publicado en: Environmental Science & Technology, Edición 59, 2025, Página(s) 8662-8672, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c13943

The decomposition and emission factors of a wide range of PFAS in diverse, contaminated organic waste fractions undergoing dry pyrolysis

Autores: Erlend Sørmo, Gabriela Castro, Michel Hubert, Viktória Licul-Kucera, Marjorie Quintanilla, Alexandros G. Asimakopoulos, Gerard Cornelissen, Hans Peter H. Arp
Publicado en: Journal of Hazardous Materials, Edición 454, 2023, Página(s) 131447, ISSN 0304-3894
Editor: Elsevier BV
DOI: 10.1016/j.jhazmat.2023.131447

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

Autores: L. Brunken, A. Vieira Silva, M. Öberg
Publicado en: Frontiers in Toxicology, Edición 7, 2025, ISSN 2673-3080
Editor: Frontiers Media SA
DOI: 10.3389/ftox.2025.1525089

Characterization and dermal bioaccessibility of residual- and listed PFAS ingredients in cosmetic products

Autores: Shahla Namazkar, Oddny Ragnarsdottir, Anton Josefsson, Felice Branzell, Sebastian Abel, Mohamed Abdallah, Stuart Harrad, Jonathan P. Benskin
Publicado en: Environmental Science: Processes & Impacts, Edición 26(2), 2024, Página(s) 259-268, ISSN 2050-7895
Editor: Royal Society of Chemistry
DOI: 10.1039/d3em00461a

Interspecies comparison of metabolism of two novel prototype PFAS

Autores: Viktória Licul-Kucera, Oddný Ragnarsdóttir, Tobias Frömel, Annemarie P. van Wezel, Thomas P. Knepper, Stuart Harrad, Mohamed Abou-Elwafa Abdallah
Publicado en: Chemosphere, Edición 351, 2024, Página(s) 141237, ISSN 1879-1298
Editor: Elsevier
DOI: 10.1016/j.chemosphere.2024.141237

Per- and polyfluoroalkyl substance (PFAS) removal from soil washing water by coagulation and flocculation

Autores: Michel Hubert, Thomas Meyn, Mona Cecilie Hansen, Sarah E. Hale, Hans Peter H. Arp
Publicado en: Water Research, Edición 249, 2024, Página(s) 120888, ISSN 0043-1354
Editor: Elsevier BV
DOI: 10.1016/j.watres.2023.120888

Dermal bioaccessibility of perfluoroalkyl substances from household dust; influence of topically applied cosmetics

Autores: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publicado en: Environmental Research, Edición 238, 2023, Página(s) 117093, ISSN 0013-9351
Editor: Academic Press
DOI: 10.1016/j.envres.2023.117093

Widespread Occurrence of Non-Extractable Fluorine in Artificial Turfs from Stockholm, Sweden

Autores: Mélanie Z. Lauria, Ayman Naim, Merle Plassmann, Jenny Fäldt, Roxana Sühring, Jonathan P. Benskin
Publicado en: Environmental Science & Technology Letters, Edición 9(8), 2022, Página(s) 666–672, ISSN 2328-8930
Editor: American Chemical Society
DOI: 10.1021/acs.estlett.2c00260

Integrated Treatment of Per- and Polyfluoroalkyl Substances in Existing Wastewater Treatment Plants─Scoping the Potential of Foam Partitioning

Autores: Sanne J. Smith, Chantal Keane, Lutz Ahrens, Karin Wiberg
Publicado en: ACS ES&T Engineering, Edición 3(9), 2023, Página(s) 1276–1285, ISSN 2690-0645
Editor: American Chemical Society
DOI: 10.1021/acsestengg.3c00091

Dermal bioavailability of perfluoroalkyl substances using in vitro 3D human skin equivalent models

Autores: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publicado en: Environment International, Edición 188, 2024, Página(s) 108772, ISSN 1873-6750
Editor: Elsevier
DOI: 10.1016/j.envint.2024.108772

Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?

Autores: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publicado en: Environmental Pollution, Edición 307, 2022, Página(s) 119478, ISSN 1873-6424
Editor: Elsevier
DOI: 10.1016/j.envpol.2022.119478

Decontamination and Surface Analysis of PFAS-Contaminated Fire Suppression System Pipes: Effects of Cleaning Agents and Temperature

Autores: Björn Bonnet, Matthew K. Sharpe, Gulaim Seisenbaeva, Leo W. Y. Yeung, Ian Ross, Lutz Ahrens
Publicado en: Environmental Science & Technology, Edición 59, 2025, Página(s) 2222-2232, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c09474

Forever legacies? Profiling historical PFAS contamination and current influence on groundwater used for drinking water

Autores: Mohammad Sadia, Marlene Kunz, Thomas ter Laak, Martin De Jonge, Merijn Schriks, Annemarie P. van Wezel
Publicado en: Science of The Total Environment, Edición 890, 2023, Página(s) 164420, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.164420

Combining Advanced Analytical Methodologies to Uncover Suspect PFAS and Fluorinated Pharmaceutical Contributions to Extractable Organic Fluorine in Human Serum (Tromsø Study)

Autores: Lara Cioni, Vladimir Nikiforov, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Silvia Dudášová, Melanie Z. Lauria, Oliver J. Lechtenfeld, Merle M. Plassmann, Thorsten Reemtsma, Torkjel M. Sandanger, Dorte Herzke
Publicado en: Environmental Science & Technology, Edición 58(29), 2024, Página(s) 12943–12953, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c03758

Measurement and modelling of sorbent-amendment impacts on seasonal and long-term PFAS transport through unsaturated soil lysimeters

Autores: Michel Hubert, Björn Bonnet, Sarah E. Hale, Erlend Sørmo, Gerard Cornelissen, Lutz Ahrens, Hans Peter H. Arp
Publicado en: Journal of Hazardous Materials, Edición 494, 2025, Página(s) 138662, ISSN 0304-3894
Editor: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.138662

Foam fractionation for removal of per- and polyfluoroalkyl substances: Towards closing the mass balance

Autores: Sanne J. Smith, Jeffrey Lewis, Karin Wiberg, Erik Wall, Lutz Ahrens
Publicado en: Science of The Total Environment, Edición 871, 2023, Página(s) 162050, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162050

Retrospective Identification of Novel and Legacy Per- and Polyfluoroalkyl Substances in German Archived Fish Livers Using a Combined High-Resolution Mass Spectrometry Approach

Autores: Silvia Dudášová, Urs Berger, Bettina Seiwert, Thorsten Reemtsma, Oliver J. Lechtenfeld, Qiuguo Fu
Publicado en: Environmental Science & Technology, Edición 59, 2025, Página(s) 12865-12877, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.4c11600

Temporal and cross-sectional associations of serum per- and polyfluoroalkyl substances (PFAS) and lipids from 1986 to 2016 − The Tromsø study

Autores: Ana Carolina M F Coêlho, Dolley Charles, Therese Haugdahl Nøst, Lara Cioni, Sandra Huber, Dorte Herzke, Charlotta Rylander, Vivian Berg, Torkjel M Sandanger
Publicado en: Environment International, Edición 199, 2025, Página(s) 109508, ISSN 0160-4120
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2025.109508

Impact of perfluoroalkyl substances (PFAS) and PFAS mixtures on lipid metabolism in differentiated HepaRG cells as a model for human hepatocytes

Autores: Faezeh Sadrabadi, Jimmy Alarcan, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Publicado en: Archives of Toxicology, 2023, ISSN 0340-5761
Editor: Springer Verlag
DOI: 10.1007/s00204-023-03649-3

Fluorine Mass Balance, including Total Fluorine, Extractable Organic Fluorine, Oxidizable Precursors, and Target Per- and Polyfluoroalkyl Substances, in Pooled Human Serum from the Tromsø Population in 1986, 2007, and 2015

Autores: Lara Cioni, Merle Plassmann, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Therese H. Nøst, Charlotta Rylander, Vladimir Nikiforov, Torkjel M. Sandanger, and Dorte Herzke
Publicado en: Environmental Science & Technology, Edición 57(40), 2023, Página(s) 14849–14860, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.3c03655

Thesis and dissertations (3)

Innovative treatment technologies for PFAS-contaminated water - Utilizing foam partitioning and exploring electrochemical oxidation

Autores: Sanne J. Smith
Publicado en: 2023, ISBN 978-91-8046-158-0
Editor: Swedish University of Agricultural Sciences
DOI: 10.54612/a.6p8i5lbs8l

Evaluating the role of the dermal pathway in driving human exposure to perfluoroalkyl substances (PFAS)

Autores: Oddný Ragnarsdóttir
Publicado en: 2024
Editor: University of Birmingham

Human Exposure to PFAS and Other Anthropogenic Organofluorine Chemicals in Tromsø between 1986 and 2015

Autores: Lara Cioni
Publicado en: 2023
Editor: UiT The Arctic University of Norway