Innovative Training Network on PER and polyfluorinated alkyl substances towards the Future Of Research and its Communication in Europe 3

Informations projet

PERFORCE3

N° de convention de subvention: 860665

DOI

10.3030/860665

Projet clôturé

Date de signature de la CE 9 Août 2019

Date de début 1 Janvier 2020

Date de fin 30 Juin 2024

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 4 160 995,92

Contribution de l’UE

€ 4 160 995,92

Coordonné par

STOCKHOLMS UNIVERSITET
Sweden

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Other (5)

Open translational research dissemination workshop

Open translational research dissemination workshop (M45)

Delivery of online seminars (webinars) I-VIII

Delivery of online seminars (webinars) I-VIII(Multiple due dates: M11, M14, M17, M20, M23, M26, M29, M32)

Blog/social media posts
Advertisement of ESR positions
Nobel Laureate Lectures

Nobel Laureate Lectures(Multiple due dates: M12 and M36)

Websites, patent fillings, videos etc. (2)

PERFORCE3 Website operational for external communications
Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III

Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III(Multiple due dates: M10, M22 and M34)

Documents, reports (5)

Fellow-only meetings I-IV

Fellow-only meetings I-IV(Multiple due dates: M10, M22, M34 and M46)

Development of a multi-matrix total organofluorine technique

Development of a multimatrix total organofluorine technique

Preliminary results from near-field air exposure, dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Preliminary results from nearfield air exposure dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Development of a multi-matrix total oxidisable precursors technique

Development of a multimatrix total oxidisable precursors technique

Report on degradation experiments on alternative precursor PFASs

Open Research Data Pilot (1)

Provide exposure and effect results to established research data repositories, regulatory institutes and authorities

Publications

Peer reviewed articles (43)

Occurrence, Fate, and Related Health Risks of PFAS in Raw and Produced Drinking Water

Auteurs: Mohammad Sadia, Ingeborg Nollen, Rick Helmus, Thomas L. ter Laak, Frederic Béen, Antonia Praetorius, Annemarie P. van Wezel
Publié dans: Environmental Science & Technology, Numéro 57(8), 2023, Page(s) 062–3074, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.2c06015

A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry

Auteurs: Mohammad Sadia, Youssef Boudguiyer, Rick Helmus, Marianne Seijo, Antonia Praetorius, Saer Samanipour
Publié dans: Analytical and Bioanalytical Chemistry, 2024, ISSN 1618-2642
Éditeur: Springer Verlag
DOI: 10.1007/s00216-024-05425-3

Influence of grain size, organic carbon and organic matter residue content on the sorption of per- and polyfluoroalkyl substances in aqueous film forming foam contaminated soils - Implications for remediation using soil washing

Auteurs: Michel Hubert, Hans Peter H. Arp, Mona Cecilie Hansen, Gabriela Castro, Thomas Meyn, Alexandros G. Asimakopoulos, Sarah E. Hale
Publié dans: Science of The Total Environment, Numéro 875, 2023, Page(s) 162668, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162668

The Need to Include a Fluorine Mass Balance in the Development of Effective Technologies for PFAS Destruction

Auteurs: Sanne J. Smith, Mélanie Lauria, Christopher P. Higgins, Kurt D. Pennell, Jens Blotevogel, Hans Peter H. Arp
Publié dans: Environmental Science & Technology, Numéro 58, 2024, Page(s) 2587-2590, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.3c10617

Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate

Auteurs: Sanne J. Smith, Karin Wiberg, Philip McCleaf, Lutz Ahrens
Publié dans: ACS ES&T Water, Numéro 2(5), 2022, Page(s) 841-851, ISSN 2690-0637
Éditeur: American Chemical Society
DOI: 10.1021/acsestwater.2c00032

Are Hazard Assessment Methods in the Assessment of Chemical Alternatives Suitable for REACH?

Auteurs: Rachel L. London, Juliane Glüge, Martin Scheringer
Publié dans: Environmental Science & Technology, Numéro 58, 2024, Page(s) 18811-18821, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c03979

Total oxidizable precursors assay for PFAS in human serum

Auteurs: Lara Cioni, Vladimir Nikiforov, Ana Carolina M. F. Coelho, Torkjel M. Sandanger, Dorte Herzke
Publié dans: Environment International, Numéro 170, 2022, Page(s) 107656, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107656

Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants

Auteurs: Viktória Licul-Kucera, Tobias Frömel, Martin Kruså, Annemarie P. van Wezel, Thomas P. Knepper
Publié dans: Chemosphere, Numéro 339, 2023, Page(s) 139563, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.139563

Legacy perfluoroalkyl acids and their oxidizable precursors in plasma samples of Norwegian women

Auteurs: Ana Carolina M. F. Coêlho, Lara Cioni, Wendy Van Dreunen, Vivian Berg, Charlotta Rylander, Ilona Urbarova, Dorte Herzke, Torkjel M. Sandanger
Publié dans: Environment International, Numéro 178, 2023, Page(s) 108026, ISSN 1873-6750
Éditeur: Elsevier
DOI: 10.1016/j.envint.2023.108026

Sorption of per- and poly-fluoroalkyl substances and their precursors on activated carbon under realistic drinking water conditions: Insights into sorbent variability and PFAS structural effects

Auteurs: Mohammad Sadia, Lola Beltrán Beut, Marko Pranić, Annemarie P. van Wezel, Thomas L. ter Laak
Publié dans: Heliyon, Numéro 10(3), 2024, Page(s)  e25130, ISSN 2405-8440
Éditeur: Elsevier
DOI: 10.1016/j.heliyon.2024.e25130

Electrochemical Oxidation for Treatment of PFAS in Contaminated Water and Fractionated Foam ─ A Pilot-Scale Study

Auteurs: Sanne J. Smith, Melanie Lauria, Lutz Ahrens, Philip McCleaf, Patrik Hollman, Sofia Bjälkefur Seroka, Timo Hamers, Hans Peter H. Arp, Karin Wiberg
Publié dans: ACS EST Water, Numéro 3(4), 2023, Page(s) 1201–1211, ISSN 2690-0637
Éditeur: American Chemical Society
DOI: 10.1021/acsestwater.2c00660

Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells

Auteurs: Lackson Kashobwe, Faezeh Sadrabadi, Lars Brunken, Ana Carolina M.F. Coelho, Torkjel M. Sandanger, Albert Braeuning, Thorsten Buhrke, Mattias Öberg, Timo Hamers, Pim.E.G. Leonards
Publié dans: Toxicology, Numéro 506, 2024, Page(s) 153862, ISSN 0300-483X
Éditeur: Elsevier BV
DOI: 10.1016/j.tox.2024.153862

Multiple-Criteria Decision Analysis for Assessments of Chemical Alternatives (MCDA-ACA)

Auteurs: Rachel L. London, Juliane Glüge, Martin Scheringer
Publié dans: Environmental Science & Technology, Numéro 58, 2024, Page(s) 19315-19324, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c03980

In vitro screening of understudied PFAS with a focus on lipid metabolism disruption

Auteurs: Lackson Kashobwe, Faezeh Sadrabadi, Albert Braeuning, Pim E. G. Leonards, Thorsten Buhrke, Timo Hamers
Publié dans: Archives of Toxicology, Numéro 98, 2024, Page(s) 3381–3395, ISSN 0340-5761
Éditeur: Springer Verlag
DOI: 10.1007/s00204-024-03814-2

Information Requirements under the Essential-Use Concept: PFAS Case Studies.

Auteurs: Juliane Glüge; Rachel London; Ian T. Cousins; Jamie C. DeWitt; Gretta Goldenman; Dorte Herzke; Rainer Lohmann; Mark A. Miller; Carla A. Ng; Sharyle Patton; Xenia Trier; Zhanyun Wang; Martin Scheringer; Martin Scheringer
Publié dans: Environmental Science & Technology, 2021, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.1c03732

Per- and polyfluoroalkyl substances (PFAS) in white-tailed sea eagle eggs from Sweden: temporal trends (1969–2021), spatial variations, fluorine mass balance, and suspect screening

Auteurs: Faiz Haque, Anne L. Soerensen, Martin Sköld, Raed Awad, Kyra M. Spaan, Mélanie Z. Lauria, Merle M. Plassmann, Jonathan P. Benskin
Publié dans: Environmental Science: Processes & Impacts, Numéro 25, 2023, Page(s) 1549-1563, ISSN 2050-7895
Éditeur: Royal Society of Chemistry 
DOI: 10.1039/d3em00141e

Shellfish and shorebirds from the East-Asian Australian flyway as bioindicators for unknown per- and polyfluoroalkyl substances using the total oxidizable precursor assay

Auteurs: Junjie Zhang, Lara Cioni, Veerle L.B. Jaspers, Alexandros G. Asimakopoulos, He-Bo Peng, Tobias A. Ross, Marcel Klaassen, Dorte Herzke
Publié dans: Journal of Hazardous Materials, Numéro 487, 2025, Page(s) 137189, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.137189

Closing the Organofluorine Mass Balance in Marine Mammals Using Suspect Screening and Machine Learning-Based Quantification

Auteurs: Mélanie Z. Lauria, Helen Sepman, Thomas Ledbetter, Merle Plassmann, Anna M. Roos, Malene Simon, Jonathan P. Benskin, Anneli Kruve
Publié dans: Environmental Science & Technology, Numéro 58, 2024, Page(s) 2458-2467, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.3c07220

A group of novel polyfluoroether substances affects lipid metabolism in human hepatocyte HepaRG cells less than classic perfluoroalkyl compounds

Auteurs: Faezeh Sadrabadi, Wiebke Alker, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Publié dans: Toxicology in Vitro, Numéro 105, 2025, Page(s) 106024, ISSN 0887-2333
Éditeur: Elsevier BV
DOI: 10.1016/j.tiv.2025.106024

Perfluoro(2-ethoxy-2-fluoroethoxy)-acetic Acid and Other Target and Suspect PFAS in the Vicinity of a Fluoropolymer Production Plant

Auteurs: Joost Dalmijn, Jonathan P. Benskin, Matthew E. Salter, Andrew J. Sweetman, Crispin J. Halsall, Jack Garnett, Ian T. Cousins
Publié dans: Environmental Science & Technology, Numéro 59(29), 2025, Page(s) 15420–15431, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.5c07856

An automated and high-throughput data processing workflow for PFAS identification in biota by direct infusion ultra-high resolution mass spectrometry

Auteurs: Silvia Dudášová, Johann Wurz, Urs Berger, Thorsten Reemtsma, Qiuguo Fu, Oliver J. Lechtenfeld
Publié dans: Analytical and Bioanalytical Chemistry, Numéro 416, 2024, Page(s) 4833–4848, ISSN 1618-2642
Éditeur: Springer Verlag
DOI: 10.1007/s00216-024-05426-2

Emission inventory of PFASs and other fluorinated organic substances for the fluoropolymer production industry in Europe

Auteurs: Joost Dalmijn, Juliane Glüge, Martin Scheringer, Ian T. Cousins
Publié dans: Environmental Science: Processes & Impacts, Numéro 26, 2024, Page(s) 269-287, ISSN 2050-7887
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3em00426k

Exploring Perfluoroalkyl and Polyfluoroalkyl Substance Presence and Potential Leaching from Reverse Osmosis Membranes: Implications for Drinking Water Treatment

Auteurs: Mohammad Sadia, Thomas L. ter Laak, Emile R. Cornelissen, Annemarie P. van Wezel
Publié dans: Environmental Science & Technology, Numéro 58(35), 2024, Page(s) 15799–15806, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c04743

HFPO-DA and Other PFAS in Air Downwind of a Fluoropolymer Production Plant in the Netherlands: Measurements and Modeling

Auteurs: Joost Dalmijn, Julia J. Shafer, Jonathan P. Benskin, Matthew E. Salter, Jana H. Johansson, Ian T. Cousins
Publié dans: Environmental Science & Technology, Numéro 59, 2025, Page(s) 8662-8672, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c13943

The decomposition and emission factors of a wide range of PFAS in diverse, contaminated organic waste fractions undergoing dry pyrolysis

Auteurs: Erlend Sørmo, Gabriela Castro, Michel Hubert, Viktória Licul-Kucera, Marjorie Quintanilla, Alexandros G. Asimakopoulos, Gerard Cornelissen, Hans Peter H. Arp
Publié dans: Journal of Hazardous Materials, Numéro 454, 2023, Page(s) 131447, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2023.131447

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

Auteurs: L. Brunken, A. Vieira Silva, M. Öberg
Publié dans: Frontiers in Toxicology, Numéro 7, 2025, ISSN 2673-3080
Éditeur: Frontiers Media SA
DOI: 10.3389/ftox.2025.1525089

Characterization and dermal bioaccessibility of residual- and listed PFAS ingredients in cosmetic products

Auteurs: Shahla Namazkar, Oddny Ragnarsdottir, Anton Josefsson, Felice Branzell, Sebastian Abel, Mohamed Abdallah, Stuart Harrad, Jonathan P. Benskin
Publié dans: Environmental Science: Processes & Impacts, Numéro 26(2), 2024, Page(s) 259-268, ISSN 2050-7895
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d3em00461a

Interspecies comparison of metabolism of two novel prototype PFAS

Auteurs: Viktória Licul-Kucera, Oddný Ragnarsdóttir, Tobias Frömel, Annemarie P. van Wezel, Thomas P. Knepper, Stuart Harrad, Mohamed Abou-Elwafa Abdallah
Publié dans: Chemosphere, Numéro 351, 2024, Page(s) 141237, ISSN 1879-1298
Éditeur: Elsevier
DOI: 10.1016/j.chemosphere.2024.141237

Per- and polyfluoroalkyl substance (PFAS) removal from soil washing water by coagulation and flocculation

Auteurs: Michel Hubert, Thomas Meyn, Mona Cecilie Hansen, Sarah E. Hale, Hans Peter H. Arp
Publié dans: Water Research, Numéro 249, 2024, Page(s) 120888, ISSN 0043-1354
Éditeur: Elsevier BV
DOI: 10.1016/j.watres.2023.120888

Dermal bioaccessibility of perfluoroalkyl substances from household dust; influence of topically applied cosmetics

Auteurs: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publié dans: Environmental Research, Numéro 238, 2023, Page(s) 117093, ISSN 0013-9351
Éditeur: Academic Press
DOI: 10.1016/j.envres.2023.117093

Widespread Occurrence of Non-Extractable Fluorine in Artificial Turfs from Stockholm, Sweden

Auteurs: Mélanie Z. Lauria, Ayman Naim, Merle Plassmann, Jenny Fäldt, Roxana Sühring, Jonathan P. Benskin
Publié dans: Environmental Science & Technology Letters, Numéro 9(8), 2022, Page(s) 666–672, ISSN 2328-8930
Éditeur: American Chemical Society
DOI: 10.1021/acs.estlett.2c00260

Integrated Treatment of Per- and Polyfluoroalkyl Substances in Existing Wastewater Treatment Plants─Scoping the Potential of Foam Partitioning

Auteurs: Sanne J. Smith, Chantal Keane, Lutz Ahrens, Karin Wiberg
Publié dans: ACS ES&T Engineering, Numéro 3(9), 2023, Page(s) 1276–1285, ISSN 2690-0645
Éditeur: American Chemical Society
DOI: 10.1021/acsestengg.3c00091

Dermal bioavailability of perfluoroalkyl substances using in vitro 3D human skin equivalent models

Auteurs: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publié dans: Environment International, Numéro 188, 2024, Page(s) 108772, ISSN 1873-6750
Éditeur: Elsevier
DOI: 10.1016/j.envint.2024.108772

Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?

Auteurs: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Publié dans: Environmental Pollution, Numéro 307, 2022, Page(s) 119478, ISSN 1873-6424
Éditeur: Elsevier
DOI: 10.1016/j.envpol.2022.119478

Decontamination and Surface Analysis of PFAS-Contaminated Fire Suppression System Pipes: Effects of Cleaning Agents and Temperature

Auteurs: Björn Bonnet, Matthew K. Sharpe, Gulaim Seisenbaeva, Leo W. Y. Yeung, Ian Ross, Lutz Ahrens
Publié dans: Environmental Science & Technology, Numéro 59, 2025, Page(s) 2222-2232, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c09474

Forever legacies? Profiling historical PFAS contamination and current influence on groundwater used for drinking water

Auteurs: Mohammad Sadia, Marlene Kunz, Thomas ter Laak, Martin De Jonge, Merijn Schriks, Annemarie P. van Wezel
Publié dans: Science of The Total Environment, Numéro 890, 2023, Page(s) 164420, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.164420

Combining Advanced Analytical Methodologies to Uncover Suspect PFAS and Fluorinated Pharmaceutical Contributions to Extractable Organic Fluorine in Human Serum (Tromsø Study)

Auteurs: Lara Cioni, Vladimir Nikiforov, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Silvia Dudášová, Melanie Z. Lauria, Oliver J. Lechtenfeld, Merle M. Plassmann, Thorsten Reemtsma, Torkjel M. Sandanger, Dorte Herzke
Publié dans: Environmental Science & Technology, Numéro 58(29), 2024, Page(s) 12943–12953, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c03758

Measurement and modelling of sorbent-amendment impacts on seasonal and long-term PFAS transport through unsaturated soil lysimeters

Auteurs: Michel Hubert, Björn Bonnet, Sarah E. Hale, Erlend Sørmo, Gerard Cornelissen, Lutz Ahrens, Hans Peter H. Arp
Publié dans: Journal of Hazardous Materials, Numéro 494, 2025, Page(s) 138662, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.138662

Foam fractionation for removal of per- and polyfluoroalkyl substances: Towards closing the mass balance

Auteurs: Sanne J. Smith, Jeffrey Lewis, Karin Wiberg, Erik Wall, Lutz Ahrens
Publié dans: Science of The Total Environment, Numéro 871, 2023, Page(s) 162050, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162050

Retrospective Identification of Novel and Legacy Per- and Polyfluoroalkyl Substances in German Archived Fish Livers Using a Combined High-Resolution Mass Spectrometry Approach

Auteurs: Silvia Dudášová, Urs Berger, Bettina Seiwert, Thorsten Reemtsma, Oliver J. Lechtenfeld, Qiuguo Fu
Publié dans: Environmental Science & Technology, Numéro 59, 2025, Page(s) 12865-12877, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.4c11600

Temporal and cross-sectional associations of serum per- and polyfluoroalkyl substances (PFAS) and lipids from 1986 to 2016 − The Tromsø study

Auteurs: Ana Carolina M F Coêlho, Dolley Charles, Therese Haugdahl Nøst, Lara Cioni, Sandra Huber, Dorte Herzke, Charlotta Rylander, Vivian Berg, Torkjel M Sandanger
Publié dans: Environment International, Numéro 199, 2025, Page(s) 109508, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2025.109508

Impact of perfluoroalkyl substances (PFAS) and PFAS mixtures on lipid metabolism in differentiated HepaRG cells as a model for human hepatocytes

Auteurs: Faezeh Sadrabadi, Jimmy Alarcan, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Publié dans: Archives of Toxicology, 2023, ISSN 0340-5761
Éditeur: Springer Verlag
DOI: 10.1007/s00204-023-03649-3

Fluorine Mass Balance, including Total Fluorine, Extractable Organic Fluorine, Oxidizable Precursors, and Target Per- and Polyfluoroalkyl Substances, in Pooled Human Serum from the Tromsø Population in 1986, 2007, and 2015

Auteurs: Lara Cioni, Merle Plassmann, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Therese H. Nøst, Charlotta Rylander, Vladimir Nikiforov, Torkjel M. Sandanger, and Dorte Herzke
Publié dans: Environmental Science & Technology, Numéro 57(40), 2023, Page(s) 14849–14860, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.3c03655

Thesis and dissertations (3)

Innovative treatment technologies for PFAS-contaminated water - Utilizing foam partitioning and exploring electrochemical oxidation

Auteurs: Sanne J. Smith
Publié dans: 2023, ISBN 978-91-8046-158-0
Éditeur: Swedish University of Agricultural Sciences
DOI: 10.54612/a.6p8i5lbs8l

Evaluating the role of the dermal pathway in driving human exposure to perfluoroalkyl substances (PFAS)

Auteurs: Oddný Ragnarsdóttir
Publié dans: 2024
Éditeur: University of Birmingham

Human Exposure to PFAS and Other Anthropogenic Organofluorine Chemicals in Tromsø between 1986 and 2015

Auteurs: Lara Cioni
Publié dans: 2023
Éditeur: UiT The Arctic University of Norway