Innovative Training Network on PER and polyfluorinated alkyl substances towards the Future Of Research and its Communication in Europe 3

Informazioni relative al progetto

PERFORCE3

ID dell’accordo di sovvenzione: 860665

DOI

10.3030/860665

Progetto chiuso

Data della firma CE 9 Agosto 2019

Data di avvio 1 Gennaio 2020

Data di completamento 30 Giugno 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 4 160 995,92

Contributo UE

€ 4 160 995,92

Coordinato da

STOCKHOLMS UNIVERSITET
Sweden

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (5)

Open translational research dissemination workshop

Open translational research dissemination workshop (M45)

Delivery of online seminars (webinars) I-VIII

Delivery of online seminars (webinars) I-VIII(Multiple due dates: M11, M14, M17, M20, M23, M26, M29, M32)

Blog/social media posts
Advertisement of ESR positions
Nobel Laureate Lectures

Nobel Laureate Lectures(Multiple due dates: M12 and M36)

Websites, patent fillings, videos etc. (2)

PERFORCE3 Website operational for external communications
Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III

Short videos / podcasts (3 per year) showcasing ESR projects and PERFORCE3 I-III(Multiple due dates: M10, M22 and M34)

Documents, reports (5)

Fellow-only meetings I-IV

Fellow-only meetings I-IV(Multiple due dates: M10, M22, M34 and M46)

Development of a multi-matrix total organofluorine technique

Development of a multimatrix total organofluorine technique

Preliminary results from near-field air exposure, dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Preliminary results from nearfield air exposure dermal exposure experiments and fluoronomic characterization of consumer products and drinking water

Development of a multi-matrix total oxidisable precursors technique

Development of a multimatrix total oxidisable precursors technique

Report on degradation experiments on alternative precursor PFASs

Open Research Data Pilot (1)

Provide exposure and effect results to established research data repositories, regulatory institutes and authorities

Pubblicazioni

Peer reviewed articles (43)

Occurrence, Fate, and Related Health Risks of PFAS in Raw and Produced Drinking Water

Autori: Mohammad Sadia, Ingeborg Nollen, Rick Helmus, Thomas L. ter Laak, Frederic Béen, Antonia Praetorius, Annemarie P. van Wezel
Pubblicato in: Environmental Science & Technology, Numero 57(8), 2023, Pagina/e 062–3074, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.2c06015

A stochastic approach for parameter optimization of feature detection algorithms for non-target screening in mass spectrometry

Autori: Mohammad Sadia, Youssef Boudguiyer, Rick Helmus, Marianne Seijo, Antonia Praetorius, Saer Samanipour
Pubblicato in: Analytical and Bioanalytical Chemistry, 2024, ISSN 1618-2642
Editore: Springer Verlag
DOI: 10.1007/s00216-024-05425-3

Influence of grain size, organic carbon and organic matter residue content on the sorption of per- and polyfluoroalkyl substances in aqueous film forming foam contaminated soils - Implications for remediation using soil washing

Autori: Michel Hubert, Hans Peter H. Arp, Mona Cecilie Hansen, Gabriela Castro, Thomas Meyn, Alexandros G. Asimakopoulos, Sarah E. Hale
Pubblicato in: Science of The Total Environment, Numero 875, 2023, Pagina/e 162668, ISSN 0048-9697
Editore: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162668

The Need to Include a Fluorine Mass Balance in the Development of Effective Technologies for PFAS Destruction

Autori: Sanne J. Smith, Mélanie Lauria, Christopher P. Higgins, Kurt D. Pennell, Jens Blotevogel, Hans Peter H. Arp
Pubblicato in: Environmental Science & Technology, Numero 58, 2024, Pagina/e 2587-2590, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.3c10617

Pilot-Scale Continuous Foam Fractionation for the Removal of Per- and Polyfluoroalkyl Substances (PFAS) from Landfill Leachate

Autori: Sanne J. Smith, Karin Wiberg, Philip McCleaf, Lutz Ahrens
Pubblicato in: ACS ES&T Water, Numero 2(5), 2022, Pagina/e 841-851, ISSN 2690-0637
Editore: American Chemical Society
DOI: 10.1021/acsestwater.2c00032

Are Hazard Assessment Methods in the Assessment of Chemical Alternatives Suitable for REACH?

Autori: Rachel L. London, Juliane Glüge, Martin Scheringer
Pubblicato in: Environmental Science & Technology, Numero 58, 2024, Pagina/e 18811-18821, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c03979

Total oxidizable precursors assay for PFAS in human serum

Autori: Lara Cioni, Vladimir Nikiforov, Ana Carolina M. F. Coelho, Torkjel M. Sandanger, Dorte Herzke
Pubblicato in: Environment International, Numero 170, 2022, Pagina/e 107656, ISSN 0160-4120
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107656

Finding a way out? Comprehensive biotransformation study of novel fluorinated surfactants

Autori: Viktória Licul-Kucera, Tobias Frömel, Martin Kruså, Annemarie P. van Wezel, Thomas P. Knepper
Pubblicato in: Chemosphere, Numero 339, 2023, Pagina/e 139563, ISSN 0045-6535
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2023.139563

Legacy perfluoroalkyl acids and their oxidizable precursors in plasma samples of Norwegian women

Autori: Ana Carolina M. F. Coêlho, Lara Cioni, Wendy Van Dreunen, Vivian Berg, Charlotta Rylander, Ilona Urbarova, Dorte Herzke, Torkjel M. Sandanger
Pubblicato in: Environment International, Numero 178, 2023, Pagina/e 108026, ISSN 1873-6750
Editore: Elsevier
DOI: 10.1016/j.envint.2023.108026

Sorption of per- and poly-fluoroalkyl substances and their precursors on activated carbon under realistic drinking water conditions: Insights into sorbent variability and PFAS structural effects

Autori: Mohammad Sadia, Lola Beltrán Beut, Marko Pranić, Annemarie P. van Wezel, Thomas L. ter Laak
Pubblicato in: Heliyon, Numero 10(3), 2024, Pagina/e  e25130, ISSN 2405-8440
Editore: Elsevier
DOI: 10.1016/j.heliyon.2024.e25130

Electrochemical Oxidation for Treatment of PFAS in Contaminated Water and Fractionated Foam ─ A Pilot-Scale Study

Autori: Sanne J. Smith, Melanie Lauria, Lutz Ahrens, Philip McCleaf, Patrik Hollman, Sofia Bjälkefur Seroka, Timo Hamers, Hans Peter H. Arp, Karin Wiberg
Pubblicato in: ACS EST Water, Numero 3(4), 2023, Pagina/e 1201–1211, ISSN 2690-0637
Editore: American Chemical Society
DOI: 10.1021/acsestwater.2c00660

Legacy and alternative per- and polyfluoroalkyl substances (PFAS) alter the lipid profile of HepaRG cells

Autori: Lackson Kashobwe, Faezeh Sadrabadi, Lars Brunken, Ana Carolina M.F. Coelho, Torkjel M. Sandanger, Albert Braeuning, Thorsten Buhrke, Mattias Öberg, Timo Hamers, Pim.E.G. Leonards
Pubblicato in: Toxicology, Numero 506, 2024, Pagina/e 153862, ISSN 0300-483X
Editore: Elsevier BV
DOI: 10.1016/j.tox.2024.153862

Multiple-Criteria Decision Analysis for Assessments of Chemical Alternatives (MCDA-ACA)

Autori: Rachel L. London, Juliane Glüge, Martin Scheringer
Pubblicato in: Environmental Science & Technology, Numero 58, 2024, Pagina/e 19315-19324, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c03980

In vitro screening of understudied PFAS with a focus on lipid metabolism disruption

Autori: Lackson Kashobwe, Faezeh Sadrabadi, Albert Braeuning, Pim E. G. Leonards, Thorsten Buhrke, Timo Hamers
Pubblicato in: Archives of Toxicology, Numero 98, 2024, Pagina/e 3381–3395, ISSN 0340-5761
Editore: Springer Verlag
DOI: 10.1007/s00204-024-03814-2

Information Requirements under the Essential-Use Concept: PFAS Case Studies.

Autori: Juliane Glüge; Rachel London; Ian T. Cousins; Jamie C. DeWitt; Gretta Goldenman; Dorte Herzke; Rainer Lohmann; Mark A. Miller; Carla A. Ng; Sharyle Patton; Xenia Trier; Zhanyun Wang; Martin Scheringer; Martin Scheringer
Pubblicato in: Environmental Science & Technology, 2021, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.1c03732

Per- and polyfluoroalkyl substances (PFAS) in white-tailed sea eagle eggs from Sweden: temporal trends (1969–2021), spatial variations, fluorine mass balance, and suspect screening

Autori: Faiz Haque, Anne L. Soerensen, Martin Sköld, Raed Awad, Kyra M. Spaan, Mélanie Z. Lauria, Merle M. Plassmann, Jonathan P. Benskin
Pubblicato in: Environmental Science: Processes & Impacts, Numero 25, 2023, Pagina/e 1549-1563, ISSN 2050-7895
Editore: Royal Society of Chemistry 
DOI: 10.1039/d3em00141e

Shellfish and shorebirds from the East-Asian Australian flyway as bioindicators for unknown per- and polyfluoroalkyl substances using the total oxidizable precursor assay

Autori: Junjie Zhang, Lara Cioni, Veerle L.B. Jaspers, Alexandros G. Asimakopoulos, He-Bo Peng, Tobias A. Ross, Marcel Klaassen, Dorte Herzke
Pubblicato in: Journal of Hazardous Materials, Numero 487, 2025, Pagina/e 137189, ISSN 0304-3894
Editore: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.137189

Closing the Organofluorine Mass Balance in Marine Mammals Using Suspect Screening and Machine Learning-Based Quantification

Autori: Mélanie Z. Lauria, Helen Sepman, Thomas Ledbetter, Merle Plassmann, Anna M. Roos, Malene Simon, Jonathan P. Benskin, Anneli Kruve
Pubblicato in: Environmental Science & Technology, Numero 58, 2024, Pagina/e 2458-2467, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.3c07220

A group of novel polyfluoroether substances affects lipid metabolism in human hepatocyte HepaRG cells less than classic perfluoroalkyl compounds

Autori: Faezeh Sadrabadi, Wiebke Alker, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Pubblicato in: Toxicology in Vitro, Numero 105, 2025, Pagina/e 106024, ISSN 0887-2333
Editore: Elsevier BV
DOI: 10.1016/j.tiv.2025.106024

Perfluoro(2-ethoxy-2-fluoroethoxy)-acetic Acid and Other Target and Suspect PFAS in the Vicinity of a Fluoropolymer Production Plant

Autori: Joost Dalmijn, Jonathan P. Benskin, Matthew E. Salter, Andrew J. Sweetman, Crispin J. Halsall, Jack Garnett, Ian T. Cousins
Pubblicato in: Environmental Science & Technology, Numero 59(29), 2025, Pagina/e 15420–15431, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.5c07856

An automated and high-throughput data processing workflow for PFAS identification in biota by direct infusion ultra-high resolution mass spectrometry

Autori: Silvia Dudášová, Johann Wurz, Urs Berger, Thorsten Reemtsma, Qiuguo Fu, Oliver J. Lechtenfeld
Pubblicato in: Analytical and Bioanalytical Chemistry, Numero 416, 2024, Pagina/e 4833–4848, ISSN 1618-2642
Editore: Springer Verlag
DOI: 10.1007/s00216-024-05426-2

Emission inventory of PFASs and other fluorinated organic substances for the fluoropolymer production industry in Europe

Autori: Joost Dalmijn, Juliane Glüge, Martin Scheringer, Ian T. Cousins
Pubblicato in: Environmental Science: Processes & Impacts, Numero 26, 2024, Pagina/e 269-287, ISSN 2050-7887
Editore: Royal Society of Chemistry
DOI: 10.1039/d3em00426k

Exploring Perfluoroalkyl and Polyfluoroalkyl Substance Presence and Potential Leaching from Reverse Osmosis Membranes: Implications for Drinking Water Treatment

Autori: Mohammad Sadia, Thomas L. ter Laak, Emile R. Cornelissen, Annemarie P. van Wezel
Pubblicato in: Environmental Science & Technology, Numero 58(35), 2024, Pagina/e 15799–15806, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c04743

HFPO-DA and Other PFAS in Air Downwind of a Fluoropolymer Production Plant in the Netherlands: Measurements and Modeling

Autori: Joost Dalmijn, Julia J. Shafer, Jonathan P. Benskin, Matthew E. Salter, Jana H. Johansson, Ian T. Cousins
Pubblicato in: Environmental Science & Technology, Numero 59, 2025, Pagina/e 8662-8672, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c13943

The decomposition and emission factors of a wide range of PFAS in diverse, contaminated organic waste fractions undergoing dry pyrolysis

Autori: Erlend Sørmo, Gabriela Castro, Michel Hubert, Viktória Licul-Kucera, Marjorie Quintanilla, Alexandros G. Asimakopoulos, Gerard Cornelissen, Hans Peter H. Arp
Pubblicato in: Journal of Hazardous Materials, Numero 454, 2023, Pagina/e 131447, ISSN 0304-3894
Editore: Elsevier BV
DOI: 10.1016/j.jhazmat.2023.131447

Selection of the critical effect size alters hazard characterization – a retrospective analysis of key studies used for risk assessments of PFAS

Autori: L. Brunken, A. Vieira Silva, M. Öberg
Pubblicato in: Frontiers in Toxicology, Numero 7, 2025, ISSN 2673-3080
Editore: Frontiers Media SA
DOI: 10.3389/ftox.2025.1525089

Characterization and dermal bioaccessibility of residual- and listed PFAS ingredients in cosmetic products

Autori: Shahla Namazkar, Oddny Ragnarsdottir, Anton Josefsson, Felice Branzell, Sebastian Abel, Mohamed Abdallah, Stuart Harrad, Jonathan P. Benskin
Pubblicato in: Environmental Science: Processes & Impacts, Numero 26(2), 2024, Pagina/e 259-268, ISSN 2050-7895
Editore: Royal Society of Chemistry
DOI: 10.1039/d3em00461a

Interspecies comparison of metabolism of two novel prototype PFAS

Autori: Viktória Licul-Kucera, Oddný Ragnarsdóttir, Tobias Frömel, Annemarie P. van Wezel, Thomas P. Knepper, Stuart Harrad, Mohamed Abou-Elwafa Abdallah
Pubblicato in: Chemosphere, Numero 351, 2024, Pagina/e 141237, ISSN 1879-1298
Editore: Elsevier
DOI: 10.1016/j.chemosphere.2024.141237

Per- and polyfluoroalkyl substance (PFAS) removal from soil washing water by coagulation and flocculation

Autori: Michel Hubert, Thomas Meyn, Mona Cecilie Hansen, Sarah E. Hale, Hans Peter H. Arp
Pubblicato in: Water Research, Numero 249, 2024, Pagina/e 120888, ISSN 0043-1354
Editore: Elsevier BV
DOI: 10.1016/j.watres.2023.120888

Dermal bioaccessibility of perfluoroalkyl substances from household dust; influence of topically applied cosmetics

Autori: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Pubblicato in: Environmental Research, Numero 238, 2023, Pagina/e 117093, ISSN 0013-9351
Editore: Academic Press
DOI: 10.1016/j.envres.2023.117093

Widespread Occurrence of Non-Extractable Fluorine in Artificial Turfs from Stockholm, Sweden

Autori: Mélanie Z. Lauria, Ayman Naim, Merle Plassmann, Jenny Fäldt, Roxana Sühring, Jonathan P. Benskin
Pubblicato in: Environmental Science & Technology Letters, Numero 9(8), 2022, Pagina/e 666–672, ISSN 2328-8930
Editore: American Chemical Society
DOI: 10.1021/acs.estlett.2c00260

Integrated Treatment of Per- and Polyfluoroalkyl Substances in Existing Wastewater Treatment Plants─Scoping the Potential of Foam Partitioning

Autori: Sanne J. Smith, Chantal Keane, Lutz Ahrens, Karin Wiberg
Pubblicato in: ACS ES&T Engineering, Numero 3(9), 2023, Pagina/e 1276–1285, ISSN 2690-0645
Editore: American Chemical Society
DOI: 10.1021/acsestengg.3c00091

Dermal bioavailability of perfluoroalkyl substances using in vitro 3D human skin equivalent models

Autori: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Pubblicato in: Environment International, Numero 188, 2024, Pagina/e 108772, ISSN 1873-6750
Editore: Elsevier
DOI: 10.1016/j.envint.2024.108772

Dermal uptake: An important pathway of human exposure to perfluoroalkyl substances?

Autori: Oddný Ragnarsdóttir, Mohamed Abou-Elwafa Abdallah, Stuart Harrad
Pubblicato in: Environmental Pollution, Numero 307, 2022, Pagina/e 119478, ISSN 1873-6424
Editore: Elsevier
DOI: 10.1016/j.envpol.2022.119478

Decontamination and Surface Analysis of PFAS-Contaminated Fire Suppression System Pipes: Effects of Cleaning Agents and Temperature

Autori: Björn Bonnet, Matthew K. Sharpe, Gulaim Seisenbaeva, Leo W. Y. Yeung, Ian Ross, Lutz Ahrens
Pubblicato in: Environmental Science & Technology, Numero 59, 2025, Pagina/e 2222-2232, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c09474

Forever legacies? Profiling historical PFAS contamination and current influence on groundwater used for drinking water

Autori: Mohammad Sadia, Marlene Kunz, Thomas ter Laak, Martin De Jonge, Merijn Schriks, Annemarie P. van Wezel
Pubblicato in: Science of The Total Environment, Numero 890, 2023, Pagina/e 164420, ISSN 0048-9697
Editore: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.164420

Combining Advanced Analytical Methodologies to Uncover Suspect PFAS and Fluorinated Pharmaceutical Contributions to Extractable Organic Fluorine in Human Serum (Tromsø Study)

Autori: Lara Cioni, Vladimir Nikiforov, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Silvia Dudášová, Melanie Z. Lauria, Oliver J. Lechtenfeld, Merle M. Plassmann, Thorsten Reemtsma, Torkjel M. Sandanger, Dorte Herzke
Pubblicato in: Environmental Science & Technology, Numero 58(29), 2024, Pagina/e 12943–12953, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c03758

Measurement and modelling of sorbent-amendment impacts on seasonal and long-term PFAS transport through unsaturated soil lysimeters

Autori: Michel Hubert, Björn Bonnet, Sarah E. Hale, Erlend Sørmo, Gerard Cornelissen, Lutz Ahrens, Hans Peter H. Arp
Pubblicato in: Journal of Hazardous Materials, Numero 494, 2025, Pagina/e 138662, ISSN 0304-3894
Editore: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.138662

Foam fractionation for removal of per- and polyfluoroalkyl substances: Towards closing the mass balance

Autori: Sanne J. Smith, Jeffrey Lewis, Karin Wiberg, Erik Wall, Lutz Ahrens
Pubblicato in: Science of The Total Environment, Numero 871, 2023, Pagina/e 162050, ISSN 0048-9697
Editore: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.162050

Retrospective Identification of Novel and Legacy Per- and Polyfluoroalkyl Substances in German Archived Fish Livers Using a Combined High-Resolution Mass Spectrometry Approach

Autori: Silvia Dudášová, Urs Berger, Bettina Seiwert, Thorsten Reemtsma, Oliver J. Lechtenfeld, Qiuguo Fu
Pubblicato in: Environmental Science & Technology, Numero 59, 2025, Pagina/e 12865-12877, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.4c11600

Temporal and cross-sectional associations of serum per- and polyfluoroalkyl substances (PFAS) and lipids from 1986 to 2016 − The Tromsø study

Autori: Ana Carolina M F Coêlho, Dolley Charles, Therese Haugdahl Nøst, Lara Cioni, Sandra Huber, Dorte Herzke, Charlotta Rylander, Vivian Berg, Torkjel M Sandanger
Pubblicato in: Environment International, Numero 199, 2025, Pagina/e 109508, ISSN 0160-4120
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2025.109508

Impact of perfluoroalkyl substances (PFAS) and PFAS mixtures on lipid metabolism in differentiated HepaRG cells as a model for human hepatocytes

Autori: Faezeh Sadrabadi, Jimmy Alarcan, Heike Sprenger, Albert Braeuning, Thorsten Buhrke
Pubblicato in: Archives of Toxicology, 2023, ISSN 0340-5761
Editore: Springer Verlag
DOI: 10.1007/s00204-023-03649-3

Fluorine Mass Balance, including Total Fluorine, Extractable Organic Fluorine, Oxidizable Precursors, and Target Per- and Polyfluoroalkyl Substances, in Pooled Human Serum from the Tromsø Population in 1986, 2007, and 2015

Autori: Lara Cioni, Merle Plassmann, Jonathan P. Benskin, Ana Carolina M. F. Coêlho, Therese H. Nøst, Charlotta Rylander, Vladimir Nikiforov, Torkjel M. Sandanger, and Dorte Herzke
Pubblicato in: Environmental Science & Technology, Numero 57(40), 2023, Pagina/e 14849–14860, ISSN 0013-936X
Editore: American Chemical Society
DOI: 10.1021/acs.est.3c03655

Thesis and dissertations (3)

Innovative treatment technologies for PFAS-contaminated water - Utilizing foam partitioning and exploring electrochemical oxidation

Autori: Sanne J. Smith
Pubblicato in: 2023, ISBN 978-91-8046-158-0
Editore: Swedish University of Agricultural Sciences
DOI: 10.54612/a.6p8i5lbs8l

Evaluating the role of the dermal pathway in driving human exposure to perfluoroalkyl substances (PFAS)

Autori: Oddný Ragnarsdóttir
Pubblicato in: 2024
Editore: University of Birmingham

Human Exposure to PFAS and Other Anthropogenic Organofluorine Chemicals in Tromsø between 1986 and 2015

Autori: Lara Cioni
Pubblicato in: 2023
Editore: UiT The Arctic University of Norway