Project description
Enhancing screening in the drug discovery pipeline will boost successful passage through it
Drug approval still takes about 14 years and the failure rate during clinical trials is about 85 %. At each phase, many targets fail due to safety and efficacy issues, in large part because research models of disease do not adequately model all human factors. SINERGIA will focus on optimising the use of four cutting-edge technologies that support in vivo modelling of drug mechanisms and effects. It brings together academic research entities, contract research organisations, and biotech and pharmaceutical companies. Implementation of better disease models in the drug discovery pipeline could significantly enhance the success and speed at which new candidates are brought from the bench to the bedside.
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacydrug discovery
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesmedical biotechnologycells technologiesstem cells
- medical and health scienceshealth sciencespersonalized medicine
- medical and health sciencesbasic medicinephysiology
Programme(s)
Coordinator
20133 Milano
Italy
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Participants (9)
4051 Basel
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6200 MD Maastricht
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656 91 Brno
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52074 Aachen
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CH-6500 Bellinzona
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20014 Nerviano Mi
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5611 ZS Eindhoven
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
20158 Milano
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The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
34132 Trieste
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