advanced technologieS for drug dIscovery and precisioN mEdicine: in vitRo modellinG human physiology and diseAse

Development of an ex vivo liver perfusion model for research purposes

Author(s): Alicia Ruppelt, Alba Pueyo Moliner, Marco Stijnen, Bart Spee, Marco Rasponi
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

GENERATION AND CHARACTERIZATION OF HUMAN IPSC-DERIVED CARDIAC ORGANOIDS FOR TRANSLATIONAL MEDICINE

Author(s): Ece Ergir, Soraia Fernandes, Francesco Niro, Daniel Sousa, Jan Vrbsky, Stefania Pagliari, Doriana Debellis, Heinz Redl, Peter Ertl, Giancarlo Forte
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 83767252566, 2022
Publisher: Mary Ann Liebert Inc. publishers

A microfluidic model of human vascularized breast cancer metastasis to bone for the study ofimmune-cancer cell interactions

Author(s): Simone Bersini, Martina Crippa, Giuseppe Talò, Anais Lamouline, Chiara Arrigoni, Matteo Moretti
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, 2023
Publisher: Springer Spektrum

Patient specific cardiac model of dilated cardiomyopathy in a beating heart-on-chip

Author(s): Ferran Lozano Juan, Soraia Fernandes, Francesco Niro, Roberta Visone, Giancarlo Forte, Marco Rasponi, Paola Occhetta
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Issue 269, 2023
Publisher: Springer Spektrum

Development and functional characterization of a microphysiological system for assessing in vitro drug toxicity and metabolism in the hepatobiliary environment

Author(s): Elisa Cauli, Claudia Piutti, Marco Rasponi, Claudio Bernardi
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Issue 37, 2023
Publisher: Springer Spektrum

3D BIOPRINTED CONSTRUCTS TO GENERATE MATURE ORGANOIDS FROM IPSC-DERIVED RENAL PROGENITORS

Author(s): Chiara Formica, Gabriele Addario, Lorenzo Moroni, Carlos Mota
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 83767228888, 2022
Publisher: Mary Ann Liebert Inc. publishers

Perfusion bioreactor as a perspective platform for rapid and personalised drug-testing on patientderived prostate cancer tissue

Author(s): Andrea Mazzoleni, Manuele Giuseppe Muraro, Arnaud Scherberich, Helge Seifert, Cyrill Rentsch, Lukas Bubendorf, Clémentine Le Magnen, Ivan Martin
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

Perfusion-based 3D in vitro model to study the interaction between prostate cancer andendothelial cells in the bone metastatic niche

Author(s): Andrea Mazzoleni, Mathéo Gwinner, Philip Michael Dettinger, Arnaud Scherberich, Clémentine Le Magnen, Ivan Martin, Manuele Giuseppe Muraro
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

uHeart: a beating heart-on-chip for culturing 3D cardiac microtissues and recording on-line cardiac electrophysiology

Author(s): Ferran Lozano, Roberta Visone, Simona Marzorati, Enrico Pesenti, Paola Occhetta, Marco Rasponi
Published in: Alternatives to Laboratory Animals - Special Issue: JRC Summer School 2021, Issue Volume 49 Issue 6, November 2021, 2021
Publisher: SAGE journals

Development of a patient-specific lab-on-chip model of dystrophin deficient cardiomyopathy

Author(s): Maria Carlos Oliveira, Stefano Piazza, Aoife Gowran, Marco Rasponi
Published in: Alternatives to Laboratory Animals - Special Issue: JRC Summer School 2021, Issue Volume 49 Issue 6, November 2021, 2021
Publisher: SAGE journals

Generation of a 3D patient-specific cardiac fibrosis model using iPSCs

Author(s): Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver de la Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Published in: 8th Advanced Summer School Interrogations at the biointerface: Fibrosis from mechanisms to the clinic, Issue 21-22/6/2022, 2022
Publisher: i3s

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model fordrug efficacy and safety assessment

Author(s): Hélia Barros Fernandes, Gabriele Addario, Filipa Castro Teixeira, Cristina Degrassi, Marco Rasponi, Carlos Domingues Mota
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Author(s): H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Published in: Biomedical Science and Engineering 2023, Issue volume 4: 209, 2023
Publisher: PAGEPress publications

A MICRO-PRECISION ELECTRO ARRAY (ΜPEA) PLATFORM INTEGRATED WITHIN A MECHANICALLY ACTIVE HEART-ON-CHIP FOR MODELLING DILATED CARDIOMYOPATHY

Author(s): Ferran Lozano-Juan, Roberta Visone, Giancarlo Forte, Paola Occhetta, Marco Rasponi
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 94238124605, 2022
Publisher: Mary Ann Liebert Inc. publishers

ENGINEERING AN EX-VIVO PERFUSION-BASED BIOREACTOR SYSTEM FOR DRUG-TESTING ON PATIENT-SPECIFIC CANCER SPECIMENS

Author(s): Manuele Giuseppe Muraro, Andrea Mazzoleni, Evrim Ceren Kabak, Arnaud Scherberich, Ivan Martin
Published in: TERMIS 6th World Congress, Issue 15-19/11/2021, 2021
Publisher: Termis

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Author(s): Andrea Mazzoleni
Published in: TERMIS 6th World Congress, Issue 15-19/11/2021, 2021
Publisher: Termis

Investigating the Determinants of Breast Cancer Dormancy in Bone

Author(s): Evrim Ceren Kabak, Sherlyn Foo, Manuele Muraro, Tiberius Preca, Arnaud Scherberich, Mohamed Bentires Alj, Ivan Martin
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

TOWARDS PHYSIOLOGICALLY RELEVANT BIOPRINTED KIDNEY IN VITRO MODELS

Author(s): Gabriele Addario, Sonja Djudjaj, Peter Boor, Lorenzo Moroni, Carlos Mota
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 62825432139, 2022
Publisher: Mary Ann Liebert Inc. publishers

Efficacy of Sorafenib treatment in a 3D hepatic cancer model

Author(s): H. Fernandes, V. Valeri, C. Degrassi, M. Rasponi, C. Mota
Published in: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023, Issue 04-05/05/2023, 2023
Publisher: SIOoC

Design and preliminary characterization of a new liveron-chip model as a valuable additional tool for assessing in vitro drug toxicity and metabolism in a similar physiological environment

Author(s): Elisa Cauli, Simona Marzorati, Marco Rasponi, Claudio Bernardi1
Published in: ALTEX Proceedings: Abstracts of the 1st Microphysiological Systems World Summit, New Orleans, 2022, 2022
Publisher: Springer

Biomechanically Stimulated 3D Endothelial Gut-on-Chip Platform to Study Immune Interactions

Author(s): Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Published in: EUROoCS Annual Meeting 2022, Issue 04-05/07/2022, 2022
Publisher: Conference presentation

BIOMECHANICALLY STIMULATED 3D ENDOTHELIAL GUT-ON-CHIP PLATFORM TO STUDY INTESTINE MICROBIOME AND IMMUNE SYSTEM INTERACTIONS

Author(s): Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 20941828449, 2022
Publisher: Mary Ann Liebert Inc. publishers

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Author(s): Francesco Niro, Daniel Pereira De Sousa, Jorge Oliver-De La Cruz, Soraia Fernandes, Stefania Pagliari, Marco Cassani, Vladimir Vinarsky, Ece Ergir, Giancarlo Forte
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 62825441237, 2022
Publisher: Mary Ann Liebert Inc. publishers

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Author(s): H. Fernandes, G. Addario, C.Degrassi, M. Rasponi, C. Mota
Published in: I CONVEGNO NAZIONALE DELLA SOCIETÀ ITALIANA ORGAN-ON-CHIP – SIOoC2023<, 2023
Publisher: SIOoC

BIOPRINTING OF A RENAL IN VITRO MODEL

Author(s): Gabriele Addario, Sonja Djudjaj, Silvia Fare’, Peter Boor, Lorenzo Moroni, Carlos Mota
Published in: TERMIS 6th World Congress, Issue 15-19/11/2021, 2021
Publisher: Termis

iPSC dilated cardiomyopathy model developed in a mechanical active 3D heart-on-chip

Author(s): Ferran Lozano-Juan
Published in: EUROoCS Annual Meeting 2022, Issue 4-5/07/2022, 2022
Publisher: Conference presentation

Perfusion-based bioreactor ex-vivo model of prostate cancer for personalized drug-testing

Author(s): Andrea Mazzoleni
Published in: ISREC SCCL SYMPOSIUM 2021, Issue 28-31/08/2021, 2021
Publisher: EPFL

Generation of a patient-specific cardiac fibrosis model to analyze lncRNA contribution to heart disease

Author(s): Daniel Sousa
Published in: Annual International PhD Conference in Biomedical Sciences, Issue 3-5/11/2021, 2021
Publisher: Masaryk University

Contribution of Fibronectin alternative splicing isoforms to myocardial fibrosis

Author(s): Francesco Niro
Published in: nnual International PhD Conference in Biomedical Sciences, Issue 3-5/11/2021, 2021
Publisher: Masaryk University

Contractile force measurement in a beating heart-on-a-chip

Author(s): Rodrigo Torres García, Roberta Visone, Paola Occhetta, Marco Rasponi
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Issue 277, 2023
Publisher: Springer Spektrum

Unveiling the function of the mechanosensor YAP in the activation of cardiac fibroblasts

Author(s): Daniel Sousa, Francesco Niro, Ece Ergir, Jorge Oliver De La Cruz, Stefania Pagliari, Soraia Fernandes, Marco Cassani, Giancarlo Forte
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

3D intestine-on-chip endothelium device to study gut microbiome interactions

Author(s): Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Published in: Alternatives to Laboratory Animals - Special Issue: JRC Summer School 2021, Issue Volume 49 Issue 6, November 2021, 2021
Publisher: SAGE journals

3D vessel-gut-on-chip platform investigating interactions between immunological system and tumoral tissue remodelling and angiogenesis

Author(s): Karol Kugiejko, Mattia Ballerini, Luigi Nezi, Marco Rasponi
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Issue 12, 2023
Publisher: Springer Spektrum

Design of a bioprinted microfluidic chip as a tumor liver model for drug screening

Author(s): Hélia Fernandes, Gabriele Addario, Cristina Degrassi, Marco Rasponi, Carlos Mota
Published in: Abstracts of the 2nd Microphysiological Systems World Summit, Berlin, 2023, Issue 321, 2023
Publisher: Springer Spektrum

Engineering a Perfusion-based Bioreactor System to Study Metastatic Breast Cancer Interactions with Bone Microenvironments

Author(s): Evrim Ceren Kabak
Published in: ISREC SCCL SYMPOSIUM 2021, Issue 28-31/08/2021, 2021
Publisher: EPFL

Towards a novel alternative toxicity model with normothermically perfused ex vivo livers based on whole porcine slaughterhouse organs

Author(s): Alicia Ruppelt, Mitch Vaessen, Marco Stijnen, Marco Rasponi
Published in: ALTEX Proceedings - Abstracts of the 11th World Congress, Issue 23/08/2021-02/09/2021, 2021
Publisher: ALTEX

GENERATION OF A PATIENT-SPECIFIC CARDIAC FIBROSIS MODEL TO ANALYZE LNCRNA CONTRIBUTION TO HEART DISEASE

Author(s): Daniel Pereira-Sousa, Francesco Niro, Ece Ergir, Jorge Oliver-De La Cruz, Stefania Pagliari, Giancarlo Forte
Published in: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022, Issue 62825434808, 2022
Publisher: Mary Ann Liebert Inc. publishers

An induced pluripotent stem cell-based model to study the role of extracellular matrix inmyocardial fibrosis

Author(s): Francesco Niro, Soraia Fernandes, Jorge Oliver De La Cruz, Marco Cassani, Daniel Pereira De Sousa, Stefania Pagliari, Vladimir Vinarsky, Marco Rasponi, Paola Occhetta, Giulio Pompilio, Elena Sommariva, Davide Rovina, Zbyněk Zdráhal, Ferran Lozano Juan, Giancarlo Forte
Published in: European Chapter of the Tissue Engineering & Regenerative Medicine International Society 2023, Issue 28-31/03/2023, 2023
Publisher: The University of Manchester

TOWARDS A NOVEL ALTERNATIVE TOXICITY MODEL WITH NORMOTHERMICALLY PERFUSED EX VIVO LIVERS BASED ON WHOLE PORCINE SLAUGHTERHOUSE ORGANS

Author(s): Alicia Ruppelt, Marco Stijnen, Marco Rasponi, Melanie Krüger
Published in: TERMIS 6th World Congress, Issue 15-19/11/2021, 2021
Publisher: Termis

Engineering High Throughput System to Study Drug Response of Metastasis Breast Cancer in Bone Microenvironments

Author(s): Evrim Ceren Kabak
Published in: DBM PhD Retreat, University of Basel, Switzerland, Issue 08-10/10/2020, 2020
Publisher: DBM PhD Retreat

It is time to have 3D humanized bioprinted renal fibrosis in vitro models!

Author(s): Gabriele Addario
Published in: It is time to have 3D humanized bioprinted renal fibrosis in vitro models!, Issue 31/10/2023, 2023
Publisher: Conference proceeding

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Author(s): Francesco Niro
Published in: Annual International PhD Conference in Biomedical Sciences, Masaryk University, Brno, 2022, 2022
Publisher: Conference presentation

Bioprinted chip as a modern approach for studying kidney fibrosis

Author(s): Gabriele Addario
Published in: International Conference on Biofabrication 2022, Issue 25-28/09/2022, 2022
Publisher: Conference presentation

Development of a PDMS platform to support 3D spheroid generation

Author(s): Hélia Fernandes
Published in: International Conference on Biofabrication 2022, Issue 25-28/09/2022, 2022
Publisher: Conference presentation

AN INDUCED PLURIPOTENT STEM CELL-BASED MODEL TO STUDY THE MECHANOBIOLOGY OF MYOCARDIAL FIBROSIS

Author(s): Francesco Niro
Published in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Issue 23-26/05/2023, 2023
Publisher: Conference presentation

Towards a renal tubulointerstitium in vitro model

Author(s): Gabriele Addario
Published in: Termis workshop Brno online, Issue 10-11/06/2021, 2021
Publisher: Conference presentation

Micro-Precision Electro Array (uPEA) platform for heart-on-chip recording

Author(s): Ferran Lozano
Published in: EUROoCS Annual Meeting 2021, Issue 01-02/07/2021, 2021
Publisher: Conference presentation

3D bioprinted human renal tubulointerstitial model to study fibrosis: providing alternatives to in vivo models

Author(s): Gabriele Addario
Published in: NBTE Annual Meeting 2023, Issue 30/11/2023-01/12/2023, 2023
Publisher: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Author(s): Andrea Mazzoleni
Published in: BaCell 3D, Basel, Issue 12-13/05/2022, 2022
Publisher: Conference presentation

Microfluidic bioprinting of a renal tubulointerstitium in vitro model

Author(s): Gabriele Addario
Published in: ESB 2021-31st Conference of the ESB, Issue 05/09/2021, 2021
Publisher: Conference presentation

Bioprinting self-aggregating kidney progenitor cells within an alginate filament

Author(s): Helen Kearney
Published in: International Conference on Biofabrication 2022, Issue 25-28/09/2022, 2022
Publisher: Conference presentation

Driving innovation

Author(s): Alicia Ruppelt
Published in: 3rd joint Meeting BELSECT/NESECC, Issue 24/09/2022, 2022
Publisher: Conference presentation

Characterization of in vitro drug toxicity and metabolism through a new liver-on-chip model

Author(s): Elisa Cauli
Published in: EUROoCS Annual Meeting 2022, Issue 4-5/07/2022, 2022
Publisher: Conference presentation

Kidney tubulointerstitium: a microfluidic bioprinting approach

Author(s): Gabriele Addario
Published in: 3D Bioprinting Conference 2021, Issue 26/01/21, 2021
Publisher: Conference presentation

Generation of the first design concept of a liver-on-chip for assessing drug toxicity and metabolism in the hepatobiliary environment

Author(s): Elisa Cauli
Published in: JRC Summer School on non-animal approaches in science: “The three R…evolution”, Issue 17-21/05/2021, 2021
Publisher: Poster presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Author(s): Riccardo Francescato
Published in: 11th Research and Innovation Day in Human Medicine of Southern Switzerland, Issue 03/06/2022, 2022
Publisher: Conference presentation

Production of a reusable micromolded microcavity insert to standardize spheroid generation for drug screening

Author(s): Hélia Fernandes
Published in: Joint 3R Symposium, Issue 19-21/09/2023, 2023
Publisher: Conference presentation

Development of a platform to generate thousands of 3D spheroids for bioprinted liver model for drug efficacy and safety assessment

Author(s): Hélia Fernandes
Published in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Issue 23-26/05/2023, 2023
Publisher: Conference presentation

Extracellular matrix stiffening effect on epithelial and fibroblast cells during kidney fibrosis

Author(s): Gabriele Addario
Published in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Issue 23-26/05/2023, 2023
Publisher: Conference presentation

CONTRACTILE FORCE MEASUREMENT IN A BEATING HEART-ON-A-CHIP

Author(s): Rodrigo Torres
Published in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Issue 23-26/05/2023, 2023
Publisher: Conference presentation

Ex vivo Liver Perfusion for Research Purposes: Can We Use Slaughterhouse Material to Reduce Animal Testing?

Author(s): Alicia Ruppelt
Published in: ASAIO 67th Annual Congress - American Society of Artificial Internal Organs, Issue 08-11/06/2022, 2022
Publisher: Conference presentation

Biofabrication of a bone marrow model for breast cancer bone metastasis personalized medicine

Author(s): Anaïs Lamouline
Published in: 11th Research and Innovation Day in Human Medicine, Issue 03/06/2022, 2022
Publisher: Conference presentation

Tubulointerstitium kidney model for future disease screening

Author(s): Gabriele Addario
Published in: NBTE 2022, Issue 04-05/04/2022, 2022
Publisher: Conference presentation

The effect of iPSC culture conditions prior to downstream kidney organoid differentiation

Author(s): Helen Kearney
Published in: Termis workshop Brno online, Issue 10-11/06/2021, 2021
Publisher: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Author(s): Andrea Mazzoleni
Published in: DBE Research Day, University of Basel, Issue 30/08/2022, 2022
Publisher: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Author(s): Helen Kearney
Published in: NWO life conference 2022, Issue 24-25/05/2022, 2022
Publisher: Conference presentation

Improving human kidney fibrosis in vitro models: a mechanical, protein, gene study

Author(s): Gabriele Addario
Published in: NBTE 2022, Issue 01-02/12/2022, 2022
Publisher: Conference presentation

Mesofluidic platform for the skeletal muscle fibrosis modeling

Author(s): Riccardo Francescato
Published in: 10th Research and Innovation Day in Human Medicine of Southern Switzerland, Issue june 2021, 2021
Publisher: Conference presentation

Bioprinting a kidney rudiment for safety drug screening

Author(s): Helen Kearney
Published in: JRC Summer School on “Non-animal Approaches in Science - Towards Sustainable Innovation 2023, Issue 23-26/05/2023, 2023
Publisher: Conference presentation

A further investigation into the use of dimethyl sulfoxide prior to the differentiation of induced pluripotent stem cells into renal organoids

Author(s): Helen Kearney
Published in: NWO life conference 2022, Netherlands 2022, Issue 24-25/05/2022, 2022
Publisher: Conference presentation

3D in vitro model to study skeletal muscle fibrosis

Author(s): Riccardo Francescato
Published in: 26th Annual Meeting of the Swiss Society for Biomaterials and Regenerative Medicine (SSB+RM2022), Issue 7-9/06/2022, 2022
Publisher: Conference presentation

Perfusion bioreactor as a prospective platform for rapid and personalised drug-testing on patient-derived prostate cancer tissue

Author(s): Andrea Mazzoleni
Published in: Biointerfaces 2022, Issue 13-15/09/2022, 2022
Publisher: Conference presentation

A renal tubulointerstitium in vitro model: hope or reality?

Author(s): Gabriele Addario
Published in: Biofabrication 2021, Issue 27-29/09/2021, 2021
Publisher: Conference presentation

uHeart: a novel heart on chip coupled with uniaxial mechanical stimulation and an integrated electrical reading system for drug cardiotoxicity studies

Author(s): Ferran Lozano
Published in: Termis workshop Brno online, Issue 10-11/06/2021, 2021
Publisher: Conference presentation

Kidney Tubulointerstitium In Vitro Model – Current Challenges and Future Prospectives?

Author(s): Gabriele Addario
Published in: Aspect BioSystems Symposium 2021 Online, Issue October 2021, 2021
Publisher: Conference presentation

Biofabrication of a meso-scale human 3D in vitro model of skeletal muscle for the study of muscular fibrosis

Author(s): Riccardo Francescato
Published in: International Conference on Biofabrication 2022, Issue 25-28/09/2022, 2022
Publisher: Conference presentation

In vitro models of breast cancer bone metastasis: analyzing drug resistance through the lens of the microenvironment

Author(s): Anaïs Lamouline; Anaïs Lamouline; Anaïs Lamouline; Simone Bersini; Simone Bersini; Simone Bersini; Matteo Moretti; Matteo Moretti; Matteo Moretti; Matteo Moretti
Published in: Frontiers in Oncology, Issue 13, 2023, ISSN 2234-943X
Publisher: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1135401

Generation and maturation of human iPSC-derived 3D organotypic cardiac microtissues in long-term culture

Author(s): Ece Ergir, Jorge Oliver-De La Cruz, Soraia Fernandes, Marco Cassani, Francesco Niro, Daniel Pereira-Sousa, Jan Vrbský, Vladimír Vinarský, Ana Rubina Perestrelo, Doriana Debellis, Natália Vadovičová, Stjepan Uldrijan, Francesca Cavalieri, Stefania Pagliari, Heinz Redl, Peter Ertl, Giancarlo Forte
Published in: Scientific Reports, Issue 12, 2022, Page(s) 21, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-22225-w

Bioprinting of kidney in vitro models: cells, biomaterials, and manufacturing techniques.

Author(s): Fransen MFJ, Addario G, Bouten CVC, Halary F, Moroni L, Mota C
Published in: Essays in Biochemistry, 2021, ISSN 0071-1365
Publisher: Portland Press, Ltd.
DOI: 10.1042/ebc20200158

Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform

Author(s): Roberta Visone, Ferran Lozano-Juan, Simona Marzorati, Massimo Walter Rivolta, Enrico Pesenti, Alberto Redaelli, Roberto Sassi, Marco Rasponi, Paola Occhetta
Published in: Toxicological Sciences, Issue kfac108, 2022, ISSN 1096-6080
Publisher: Oxford University Press
DOI: 10.1093/toxsci/kfac108

A microfluidic model of human vascularized breast cancer metastasis to bone for the study of neutrophil-cancer cell interactions

Author(s): Martina Crippa, Giuseppe Talò, Anaïs Lamouline, Sara Bolis, Chiara Arrigoni, Simone Bersini, Matteo Moretti
Published in: Materials Today Bio, Issue 17, 2022, Page(s) 100460, ISSN 2590-0064
Publisher: Elsevier
DOI: 10.1016/j.mtbio.2022.100460

Normothermic Ex Vivo Liver Platform Using Porcine Slaughterhouse Livers for Disease Modeling

Author(s): M Krüger, A Ruppelt, B Kappler, E Van Soest, RA Samsom, GCM Grinwis, N Geijsen, JB Helms, M Stijnen, Marco, L Kock, M Rasponi, HS Kooistra
Published in: Bioengineering, Issue 9, 2022, Page(s) 471-489, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering9090471

Endothelial-mesenchymal transition in skeletal muscle: Opportunities and challenges from 3D microphysiological systems

Author(s): Riccardo Francescato, Matteo Moretti, Simone Bersini
Published in: Bioengineering & Translational Medicine, 2024, ISSN 2380-6761
Publisher: Wiley
DOI: 10.1002/btm2.10644

Are slaughterhouse-obtained livers suitable for use in <i>ex vivo</i> perfusion research?

Author(s): Ruppelt, Alicia; Pijnenburg, Iris; Pappers, Claire; Samsom, Roos-Anne; Kock, Linda; Grinwis, Guy C. M.; Spee, Bart; Rasponi, Marco; Stijnen, Marco
Published in: Journal of International Medical Research, Issue Vol 51(4), 2023, ISSN 0300-0605
Publisher: Cambridge Medical Publications
DOI: 10.1177/03000605231189651

3D Printed Tubulointerstitium Chip as an In Vitro Testing Platform

Author(s): Addario, Gabriele; Eussen, Daphne; Djudjaj, Sonja; Boor, Peter; Moroni, Lorenzo; Mota, Carlos
Published in: Macromolecular bioscience, Issue 2300440, 2023, Page(s) 1-12, ISSN 1616-5187
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/mabi.202300440

Microfluidic bioprinting towards a renal in vitro model

Author(s): Gabriele Addario, Sonja Djudjaj, Silvia Farè, Peter Boor, Lorenzo Moroni, Carlos Mota
Published in: Bioprinting, 2020, ISSN 2405-8866
Publisher: Elsevier BV
DOI: 10.1016/j.bprint.2020.e00108

Current strategies of mechanical stimulation for maturation of cardiac microtissues

Author(s): Maria Carlos-Oliveira, Ferran Lozano-Juan, Paola Occhetta, Roberta Visone, Marco Rasponi
Published in: Biophysical Reviews, Issue 13/5, 2021, Page(s) 717-727, ISSN 1867-2450
Publisher: Springer Verlag
DOI: 10.1007/s12551-021-00841-6

Maintaining Liver Functionality Ex Vivo: From Platform Design to Appliaction

Author(s): Alicia Ruppelt
Published in: PhD Thesis in Bioengineering at Politecnico di Milano, 2023
Publisher: Politecnico di Milano

Set up and initial qualification of a microfluidic system for assessing drug toxicity and metabolism in the hepatobiliary environment

Author(s): Elisa Cauli
Published in: PhD Thesis in Bioengineering at Politecnico di Milano, 2024
Publisher: Politecnico di Milano

Biofabrication of a 3D in vitro model of human skeletal muscle for fibrosis modeling and drug development

Author(s): Riccardo Francescato
Published in: PhD Thesis in Bioengineering at Politecnico di Milano, 2024
Publisher: Politecnico di Milano

Biofabrication of 3D Human Muscle Model with Vascularization and Endomysium

Author(s): Bersini S, Francescato R, Moretti M.
Published in: """Organ-on-a-Chip"" in the series ""Methods in Molecular Biology""", 2021, Page(s) 213-230, ISSN 1940-6029
Publisher: Springer Nature
DOI: 10.1007/978-1-0716-1693-2_13

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