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C-H Activation for Industrial Renewal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

ESR positions advertised (opens in new window)

Preparation of the announcements for the ESR positions and their publication following the conditions specified in CA

Submission of PhD theses (opens in new window)

Submission of PhD theses by all 15 ESRs

Award of PhD Degrees (opens in new window)

Award of PhD Degrees for all 15 ESRs

Report on training activities (locally delivered training and network-wide events) (opens in new window)

Organization of various training events, as specified in the Grant Agreement and preparation of reports on these training events.

Report on dissemination activities (opens in new window)

Witing of regular reports on dissemination actions (M12,24,36,48)

Report on public engagement activities (opens in new window)

A regular report on public engagement activities (M12,24,36,48)

Publications

Electrocatalytic Formal C(sp<sup>2</sup>)−H Alkylations via Nickel‐Catalyzed Cross‐Electrophile Coupling with Versatile Arylsulfonium Salts (opens in new window)

Author(s): Takuya Michiyuki, Simon L. Homölle, Neeraj K. Pandit, Lutz Ackermann
Published in: Angewandte Chemie International Edition, Issue 63, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401198

Ruthenium-Catalyzed Aminocarbonylation with Isocyanates Through Weak Coordinating Groups (opens in new window)

Author(s): Elisa Y. Lai, Binbin Yuan, Prof. Dr. Lutz Ackermann, Dr. Magnus J. Johansson
Published in: Chemistry A European Journal, 2023, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202302023

Gold-Catalyzed 1,2-Aryl Shift and Double Alkyne Benzannulation (opens in new window)

Author(s): Gana Sanil, Maciej Krzeszewski, Wojciech Chaładaj, Witold Danikiewicz, Iryna Knysh, Łukasz Dobrzycki, Olga Staszewska-Krajewska, Michał K. Cyrański, Denis Jacquemin and Daniel T. Gryko
Published in: Angewandte Chemie International Edition, Issue e202311123, 2023, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202311123

C1‐4 Alkylation of Aryl Bromides with Light Alkanes enabled by Metallaphotocatalysis in Flow (opens in new window)

Author(s): Antonio Pulcinella, Prakash Chandra Tiwari, Alberto Luridiana, Ken Yamazaki, Daniele Mazzarella, Akshay K. Sadhoe, Antonella Ilenia Alfano, Eveline H. Tiekink, Trevor A. Hamlin, Timothy Noel
Published in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202413846

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification (opens in new window)

Author(s): Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39747-0

Visible light-induced ruthenium(<scp>ii</scp>)-catalyzed hydroarylation of unactivated olefins (opens in new window)

Author(s): Sven Trienes, Stéphane Golling, Matthew H. Gieuw, Marco Di Matteo, Lutz Ackermann
Published in: Chemical Science, Issue 15, 2024, Page(s) 19037-19043, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4sc06005a

High-Throughput Enabled Iridium-Catalyzed C–H Borylation Platform for Late-Stage Functionalization (opens in new window)

Author(s): Janis M. Zakis, Rebeka A. Lipina, Sharon Bell, Simon R. Williams, Maurus Mathis, Magnus J. Johansson, Joanna Wencel-Delord, Tomas Smejkal
Published in: ACS Catalysis, 2025, Page(s) 3525-3534, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.4c07711

Late-stage peptide labeling with near-infrared fluorogenic nitrobenzodiazoles by manganese-catalyzed C–H activation (opens in new window)

Author(s): Tsuyoshi Oyama, Lorena Mendive-Tapia, Verity Cowell, Adelina Kopp, Marc Vendrell and Lutz Ackermann
Published in: Chemical Science, Issue 14, 2023, Page(s) 5728-5733, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3sc01868g

Fluorescent coumarin-alkynes for labeling of amino acids and peptides <i>via</i> manganese(<scp>i</scp>)-catalyzed C–H alkenylation (opens in new window)

Author(s): Adelina Kopp, Tsuyoshi Oyama, Lutz Ackermann
Published in: Chemical Communications, Issue 60, 2024, Page(s) 5423-5426, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4cc00361f

Do we really need ligands in Ir-catalyzed C–H borylation? (opens in new window)

Author(s): Janis M. Zakis, Simone L. Kuhn, Joanna Wencel-Delord, Tomas Smejkal
Published in: CHIMIA, Issue 78, 2024, Page(s) 513-517, ISSN 0009-4293
Publisher: Schweizerische Chemische Gedellschaft
DOI: 10.2533/chimia.2024.513

1,4-Dihydropyrrolo[3,2-<i>b</i>]pyrroles with Two Embedded Heptagons via Alkyne Annulation (opens in new window)

Author(s): Gana Sanil, Łukasz Dobrzycki, Michał K. Cyrański, Denis Jacquemin, Wojciech Chaładaj, Daniel T. Gryko
Published in: The Journal of Organic Chemistry, Issue 90, 2025, Page(s) 614-622, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.4c02538

Homogeneous catalytic C(sp 3 )–H functionalization of gaseous alkanes (opens in new window)

Author(s): Antonio Pulcinella, Daniele Mazzarella, Timothy Noël
Published in: Chemical Communications, 2021, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc04073a

Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position (opens in new window)

Author(s): Pascal Hauk, Valérie Mazan, Fabrice Gallou and Joanna Wencel-Delord
Published in: Chemical Science, 2023, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3sc03708h

Deoxygenative photochemical alkylation of secondary amides enables a streamlined synthesis of substituted amines (opens in new window)

Author(s): Antonio Pulcinella, Stefano Bonciolini, Robin Stuhr, Damiano Diprima, Minh Thao Tran, Magnus Johansson, Axel Jacobi von Wangelin, Timothy Noël
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56234-w

Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water (opens in new window)

Author(s): Julia Struwe, Tsuyoshi Oyama, Fabrice Gallou, Lutz Ackermann
Published in: Synlett, Issue 35, 2024, ISSN 0936-5214
Publisher: Georg Thieme Verlag
DOI: 10.1055/a-2268-4678

Next-generation functional surfactant for mild C−H arylation under micellar conditions (opens in new window)

Author(s): Pascal Hauk, Sven Trienes, Fabrice Gallou, Lutz Ackermann, Joanna Wencel-Delord
Published in: Chem Catalysis, Issue 4, 2024, Page(s) 101146, ISSN 2667-1093
Publisher: Elsevier Inc
DOI: 10.1016/j.checat.2024.101146

Cyclometallated complexes as catalysts for C–H activation and functionalization (opens in new window)

Author(s): Janis Mikelis Zakis, Tomas Smejkal, Joanna Wencel-Delord
Published in: Chemical Communications, 2021, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cc05195d

Structural and solvent modulation of symmetry-breaking charge-transfer pathways in molecular triads (opens in new window)

Author(s): Chinju Govind, Evangelos Balanikas, Gana Sanil, Daniel T. Gryko, Eric Vauthey
Published in: Chemical Science, Issue 15, 2024, Page(s) 17362-17371, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4sc05419a

Air-stable bis-cyclometallated iridium catalysts for ortho-directed C(sp2)–H borylation (opens in new window)

Author(s): Janis Zakis, Antonis Messinis, Lutz Ackermann, Tomas Smejkal, Joanna Wencel-Delord
Published in: Advanced Synthesis & Catalysis, 2024, ISSN 1615-4150
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.202301411

Electrochemical Preparation and Transformation of Sulfonium Salts (opens in new window)

Author(s): Takuya Michiyuki, Lutz Ackermann
Published in: ChemElectroChem, 2025, ISSN 2196-0216
Publisher: ChemElectroChem
DOI: 10.1002/celc.202400711

Mechanochemical Ball Milling Approach to C(sp<sup>3</sup>)‐H Functionalization of 8‐Methylquinolines (opens in new window)

Author(s): Nanditha Kattukudiyil Narayanan, Michael Schnürch
Published in: ChemCatChem, 2024, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202401613

Easy access to polyhalogenated biaryls: regioselective (di)halogenation of hypervalent bromines and chlorines (opens in new window)

Author(s): Daniel Carter Martos, Maxime de Abreu, Pascal Hauk, Philipp Fackler and Joanna Wencel-Delord
Published in: Chemical Science, Issue 15, 2024, Page(s) 6770-6776, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4sc01234h

The Vinyl Group: Small but Mighty – Transition Metal Catalyzed and Non‐Catalyzed Vinylation Reactions (opens in new window)

Author(s): Eleni Papaplioura, Maëva Mercier, Soufyan Jerhaoui, Michael Schnürch
Published in: ChemCatChem, 2024, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202400513

Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow (opens in new window)

Author(s): Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel T. Gryko, Timothy Noel
Published in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202403271

Metal-ligand cooperation in the catalytic oxidation of (R)-carvone by Ga(NO3)3/H2O2 (opens in new window)

Author(s): Gilvan A. Correia, Marcos L. de Araújo, Wagner A. Carvalho, Mirela Sairre, Giselle Cerchiaro, Lidia S. Shul'pina, Yuriy N. Kozlov, Georgiy B. Shul´pin, Alexander M. Kirillov, Dalmo Mandelli
Published in: Molecular Catalysis, Issue 528, 2024, Page(s) 112457, ISSN 2468-8231
Publisher: Sciendirect
DOI: 10.1016/j.mcat.2022.112457

Organic synthesis in Aqueous Multiphase Systems — Challenges and opportunities ahead of us (opens in new window)

Author(s): Pascal Hauk, Joanna Wencel-Delord, Lutz Ackermann, Peter Walde, Fabrice Gallou
Published in: Current Opinion in Colloid & Interface Science, Issue 56, 2021, Page(s) 101506, ISSN 1359-0294
Publisher: Pergamon Press
DOI: 10.1016/j.cocis.2021.101506

Photocatalytic Alkylation of C(sp 3 )−H Bonds Using Sulfonylhydrazones** (opens in new window)

Author(s): Antonio Pulcinella; Stefano Bonciolini; Florian Lukas; Andrea Sorato; Timothy Noël
Published in: Angewandte Chemie, 135(3):e202215374., Issue 1, 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202215374

Modular allylation of C(sp3)−H bonds by combining decatungstate photocatalysis and HWE olefination in flow (opens in new window)

Author(s): Luca Capaldo, Stefano Bonciolini, Antonio Pulcinella, Manuel Nuno and Timothy Noel
Published in: Chemical Science, 2022, ISSN 2041-6520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2sc01581a

Tetraethylammonium Salts as Solid, Easy to Handle Ethylene Precursors and Their Application in Mizoroki–Heck Coupling (opens in new window)

Author(s): Eleni Papaplioura, Maëva Mercier, Michael E. Muratore, Tobias Biberger, Soufyan Jerhaoui, and Michael Schnürch
Published in: The Journal of Organic Chemistry, 2024, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.3c02867

Rapid and Direct Photocatalytic C(sp3)‒H Acylation and Arylation in Flow (opens in new window)

Author(s): Daniele Mazzarella, Antonio Pulcinella, Loic Bovy, Remy Broersma, Timothy Noel
Published in: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202108987

Photo‐Induced Ruthenium‐Catalyzed C−H Arylation Polymerization at Ambient Temperature (opens in new window)

Author(s): Takuya Michiyuki, Isaac Maksso, Lutz Ackermann
Published in: Angewandte Chemie International Edition, Issue 63, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400845

Photocatalytic Late-stage Functionalization of Dehydroalanine-derived Peptides in Batch and Flow (opens in new window)

Author(s): Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel Gryko, Timothy Noel
Published in: ChemRxiv, 2024, ISSN 2573-2293
Publisher: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-6fgqv

2-(o-Tolyl) Pyridine as Ligand Improves the Efficiency in Ketone Directed ortho-Arylation (opens in new window)

Author(s): Nanditha Kattukudiyil Narayanan, Prof. Dr. Ernst Pittenauer, Prof. Dr. Michael Schnürch
Published in: European Journal of Organic Chemistry, 2023, ISSN 1434-193X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202300759

Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes (opens in new window)

Author(s): Stefano Bonciolini, Antonio Pulcinella, Matteo Leone, Debora Schiroli, Adrián Luguera Ruiz, Andrea Sorato, Maryne A. J. Dubois, Ranganath Gopalakrishnan, Geraldine Masson, Nicola Della Ca’, Stefano Protti, Maurizio Fagnoni, Eli Zysman-Colman, Magnus Johansson, Timothy Noël
Published in: Nature Communications, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-45804-z

Efficient synthesis of 2‐arylpropionitriles via selective monomethylation of aryl acetonitriles using an easy to handle methylation agent (opens in new window)

Author(s): Eleni Papaplioura, Johanna Templ, Nina Wildhack, Michael Schnürch
Published in: European Journal of Organic Chemistry, 2024, ISSN 1434-193X
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202400693

Remote C−H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta-C-Aryl Glycosides (opens in new window)

Author(s): Jun Wu, Dr. Nikolaos Kaplaneris, Julia Pöhlmann, Takuya Michiyuki, Binbin Yuan, Prof. Dr. Lutz Ackermann
Published in: Angew Chem. Int. Ed., 2022, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202208620

Adding value to terpenes: copper-catalyzed oxidation of α-pinene in water under micellar conditions (opens in new window)

Author(s): Gilvan A. Correia, Chris H. J. Franco, Marina V. Kirillova, Fabrice Gallou, Alexander M. Kirillov
Published in: Green Chemistry, 2025, ISSN 1463-9262
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4gc06525e

Pd-Catalyzed C(sp<sup>2</sup>)–H/C(sp<sup>2</sup>)–H Coupling of Limonene (opens in new window)

Author(s): Marco Di Matteo, Anna Gagliardi, Alexandre Pradal, Luis F. Veiros, Fabrice Gallou, Giovanni Poli
Published in: The Journal of Organic Chemistry, Issue 89, 2024, Page(s) 10451-10461, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.4c00501

Selective C-H Activation of Terpenes

Author(s): Marco Di Matteo
Published in: 2024
Publisher: HAL

Application of non-volatile reagents for the introduction of short hydrocarbon chains (opens in new window)

Author(s): Eleni Papaplioura
Published in: 2024
Publisher: reposiTUm
DOI: 10.34726/hss.2024.95824

Photocatalytic strategies for the valorization of feedstock chemicals in batch and flow

Author(s): Antonio Pulcinella
Published in: 2025
Publisher: UvA-DARE

The chemistry of 1,4-dihydropyrrolo[3,2-b]pyrroles (opens in new window)

Author(s): Gana Sanil, Beata Koszarna, Yevgen M.Poronik, Olena Vakuliuk, Bartosz Szymański, Damian Kusy, Daniel T. Gryko
Published in: Advances in Heterocyclic Chemistry, 2022, Page(s) 335-409
Publisher: Elsevier
DOI: 10.1016/bs.aihch.2022.04.002

Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow (opens in new window)

Author(s): Prakash Chandra Tiwari, Antonio Pulcinella, Emil Hodzic, Timothy Noel
Published in: 2025
Publisher: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2025-wr8br

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