C-H Activation for Industrial Renewal

Informazioni relative al progetto

CHAIR

ID dell’accordo di sovvenzione: 860762

DOI

10.3030/860762

Progetto chiuso

Data della firma CE 22 Giugno 2020

Data di avvio 1 Luglio 2020

Data di completamento 31 Dicembre 2024

Finanziato da

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Costo totale

€ 3 938 269,68

Contributo UE

€ 3 938 269,68

Coordinato da

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS fornisce collegamenti ai risultati finali pubblici e alle pubblicazioni dei progetti ORIZZONTE.

I link ai risultati e alle pubblicazioni dei progetti del 7° PQ, così come i link ad alcuni tipi di risultati specifici come dataset e software, sono recuperati dinamicamente da .OpenAIRE .

Risultati finali

Other (3)

ESR positions advertised

Preparation of the announcements for the ESR positions and their publication following the conditions specified in CA

Submission of PhD theses

Submission of PhD theses by all 15 ESRs

Award of PhD Degrees

Award of PhD Degrees for all 15 ESRs

Documents, reports (3)

Report on training activities (locally delivered training and network-wide events)

Organization of various training events, as specified in the Grant Agreement and preparation of reports on these training events.

Report on dissemination activities

Witing of regular reports on dissemination actions (M12,24,36,48)

Report on public engagement activities

A regular report on public engagement activities (M12,24,36,48)

Pubblicazioni

Peer reviewed articles (38)

Electrocatalytic Formal C(sp²)−H Alkylations via Nickel‐Catalyzed Cross‐Electrophile Coupling with Versatile Arylsulfonium Salts

Autori: Takuya Michiyuki, Simon L. Homölle, Neeraj K. Pandit, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202401198

Ruthenium-Catalyzed Aminocarbonylation with Isocyanates Through Weak Coordinating Groups

Autori: Elisa Y. Lai, Binbin Yuan, Prof. Dr. Lutz Ackermann, Dr. Magnus J. Johansson
Pubblicato in: Chemistry A European Journal, 2023, ISSN 0947-6539
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202302023

Gold-Catalyzed 1,2-Aryl Shift and Double Alkyne Benzannulation

Autori: Gana Sanil, Maciej Krzeszewski, Wojciech Chaładaj, Witold Danikiewicz, Iryna Knysh, Łukasz Dobrzycki, Olga Staszewska-Krajewska, Michał K. Cyrański, Denis Jacquemin and Daniel T. Gryko
Pubblicato in: Angewandte Chemie International Edition, Numero e202311123, 2023, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202311123

C1‐4 Alkylation of Aryl Bromides with Light Alkanes enabled by Metallaphotocatalysis in Flow

Autori: Antonio Pulcinella, Prakash Chandra Tiwari, Alberto Luridiana, Ken Yamazaki, Daniele Mazzarella, Akshay K. Sadhoe, Antonella Ilenia Alfano, Eveline H. Tiekink, Trevor A. Hamlin, Timothy Noel
Pubblicato in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202413846

Electrocatalyzed direct arene alkenylations without directing groups for selective late-stage drug diversification

Autori: Zhipeng Lin, Uttam Dhawa, Xiaoyan Hou, Max Surke, Binbin Yuan, Shu-Wen Li, Yan-Cheng Liou, Magnus J. Johansson, Li-Cheng Xu, Chen-Hang Chao, Xin Hong, Lutz Ackermann
Pubblicato in: Nature Communications, Numero 14, 2023, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-023-39747-0

Visible light-induced ruthenium(<scp>ii</scp>)-catalyzed hydroarylation of unactivated olefins

Autori: Sven Trienes, Stéphane Golling, Matthew H. Gieuw, Marco Di Matteo, Lutz Ackermann
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 19037-19043, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc06005a

High-Throughput Enabled Iridium-Catalyzed C–H Borylation Platform for Late-Stage Functionalization

Autori: Janis M. Zakis, Rebeka A. Lipina, Sharon Bell, Simon R. Williams, Maurus Mathis, Magnus J. Johansson, Joanna Wencel-Delord, Tomas Smejkal
Pubblicato in: ACS Catalysis, 2025, Pagina/e 3525-3534, ISSN 2155-5435
Editore: American Chemical Society
DOI: 10.1021/acscatal.4c07711

Late-stage peptide labeling with near-infrared fluorogenic nitrobenzodiazoles by manganese-catalyzed C–H activation

Autori: Tsuyoshi Oyama, Lorena Mendive-Tapia, Verity Cowell, Adelina Kopp, Marc Vendrell and Lutz Ackermann
Pubblicato in: Chemical Science, Numero 14, 2023, Pagina/e 5728-5733, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc01868g

Fluorescent coumarin-alkynes for labeling of amino acids and peptides <i>via</i> manganese(<scp>i</scp>)-catalyzed C–H alkenylation

Autori: Adelina Kopp, Tsuyoshi Oyama, Lutz Ackermann
Pubblicato in: Chemical Communications, Numero 60, 2024, Pagina/e 5423-5426, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d4cc00361f

Do we really need ligands in Ir-catalyzed C–H borylation?

Autori: Janis M. Zakis, Simone L. Kuhn, Joanna Wencel-Delord, Tomas Smejkal
Pubblicato in: CHIMIA, Numero 78, 2024, Pagina/e 513-517, ISSN 0009-4293
Editore: Schweizerische Chemische Gedellschaft
DOI: 10.2533/chimia.2024.513

1,4-Dihydropyrrolo[3,2-<i>b</i>]pyrroles with Two Embedded Heptagons via Alkyne Annulation

Autori: Gana Sanil, Łukasz Dobrzycki, Michał K. Cyrański, Denis Jacquemin, Wojciech Chaładaj, Daniel T. Gryko
Pubblicato in: The Journal of Organic Chemistry, Numero 90, 2025, Pagina/e 614-622, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.4c02538

Homogeneous catalytic C(sp 3 )–H functionalization of gaseous alkanes

Autori: Antonio Pulcinella, Daniele Mazzarella, Timothy Noël
Pubblicato in: Chemical Communications, 2021, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d1cc04073a

Micellar catalysis: a green solution to enable undirected and mild C–H activation of (oligo)thiophenes at the challenging β-position

Autori: Pascal Hauk, Valérie Mazan, Fabrice Gallou and Joanna Wencel-Delord
Pubblicato in: Chemical Science, 2023, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d3sc03708h

Deoxygenative photochemical alkylation of secondary amides enables a streamlined synthesis of substituted amines

Autori: Antonio Pulcinella, Stefano Bonciolini, Robin Stuhr, Damiano Diprima, Minh Thao Tran, Magnus Johansson, Axel Jacobi von Wangelin, Timothy Noël
Pubblicato in: Nature Communications, Numero 16, 2025, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-025-56234-w

Manganese(I)-Catalyzed C–H Allylation of Tryptophans and Their Oligopeptides On Water

Autori: Julia Struwe, Tsuyoshi Oyama, Fabrice Gallou, Lutz Ackermann
Pubblicato in: Synlett, Numero 35, 2024, ISSN 0936-5214
Editore: Georg Thieme Verlag
DOI: 10.1055/a-2268-4678

Next-generation functional surfactant for mild C−H arylation under micellar conditions

Autori: Pascal Hauk, Sven Trienes, Fabrice Gallou, Lutz Ackermann, Joanna Wencel-Delord
Pubblicato in: Chem Catalysis, Numero 4, 2024, Pagina/e 101146, ISSN 2667-1093
Editore: Elsevier Inc
DOI: 10.1016/j.checat.2024.101146

Cyclometallated complexes as catalysts for C–H activation and functionalization

Autori: Janis Mikelis Zakis, Tomas Smejkal, Joanna Wencel-Delord
Pubblicato in: Chemical Communications, 2021, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/d1cc05195d

Structural and solvent modulation of symmetry-breaking charge-transfer pathways in molecular triads

Autori: Chinju Govind, Evangelos Balanikas, Gana Sanil, Daniel T. Gryko, Eric Vauthey
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 17362-17371, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc05419a

Air-stable bis-cyclometallated iridium catalysts for ortho-directed C(sp2)–H borylation

Autori: Janis Zakis, Antonis Messinis, Lutz Ackermann, Tomas Smejkal, Joanna Wencel-Delord
Pubblicato in: Advanced Synthesis & Catalysis, 2024, ISSN 1615-4150
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.202301411

Electrochemical Preparation and Transformation of Sulfonium Salts

Autori: Takuya Michiyuki, Lutz Ackermann
Pubblicato in: ChemElectroChem, 2025, ISSN 2196-0216
Editore: ChemElectroChem
DOI: 10.1002/celc.202400711

Mechanochemical Ball Milling Approach to C(sp³)‐H Functionalization of 8‐Methylquinolines

Autori: Nanditha Kattukudiyil Narayanan, Michael Schnürch
Pubblicato in: ChemCatChem, 2024, ISSN 1867-3880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202401613

Easy access to polyhalogenated biaryls: regioselective (di)halogenation of hypervalent bromines and chlorines

Autori: Daniel Carter Martos, Maxime de Abreu, Pascal Hauk, Philipp Fackler and Joanna Wencel-Delord
Pubblicato in: Chemical Science, Numero 15, 2024, Pagina/e 6770-6776, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d4sc01234h

The Vinyl Group: Small but Mighty – Transition Metal Catalyzed and Non‐Catalyzed Vinylation Reactions

Autori: Eleni Papaplioura, Maëva Mercier, Soufyan Jerhaoui, Michael Schnürch
Pubblicato in: ChemCatChem, 2024, ISSN 1867-3880
Editore: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202400513

Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow

Autori: Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel T. Gryko, Timothy Noel
Pubblicato in: Angewandte Chemie International Edition, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202403271

Metal-ligand cooperation in the catalytic oxidation of (R)-carvone by Ga(NO3)3/H2O2

Autori: Gilvan A. Correia, Marcos L. de Araújo, Wagner A. Carvalho, Mirela Sairre, Giselle Cerchiaro, Lidia S. Shul'pina, Yuriy N. Kozlov, Georgiy B. Shul´pin, Alexander M. Kirillov, Dalmo Mandelli
Pubblicato in: Molecular Catalysis, Numero 528, 2024, Pagina/e 112457, ISSN 2468-8231
Editore: Sciendirect
DOI: 10.1016/j.mcat.2022.112457

Organic synthesis in Aqueous Multiphase Systems — Challenges and opportunities ahead of us

Autori: Pascal Hauk, Joanna Wencel-Delord, Lutz Ackermann, Peter Walde, Fabrice Gallou
Pubblicato in: Current Opinion in Colloid & Interface Science, Numero 56, 2021, Pagina/e 101506, ISSN 1359-0294
Editore: Pergamon Press
DOI: 10.1016/j.cocis.2021.101506

Photocatalytic Alkylation of C(sp 3 )−H Bonds Using Sulfonylhydrazones**

Autori: Antonio Pulcinella; Stefano Bonciolini; Florian Lukas; Andrea Sorato; Timothy Noël
Pubblicato in: Angewandte Chemie, 135(3):e202215374., Numero 1, 2022, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202215374

Modular allylation of C(sp3)−H bonds by combining decatungstate photocatalysis and HWE olefination in flow

Autori: Luca Capaldo, Stefano Bonciolini, Antonio Pulcinella, Manuel Nuno and Timothy Noel
Pubblicato in: Chemical Science, 2022, ISSN 2041-6520
Editore: Royal Society of Chemistry
DOI: 10.1039/d2sc01581a

Tetraethylammonium Salts as Solid, Easy to Handle Ethylene Precursors and Their Application in Mizoroki–Heck Coupling

Autori: Eleni Papaplioura, Maëva Mercier, Michael E. Muratore, Tobias Biberger, Soufyan Jerhaoui, and Michael Schnürch
Pubblicato in: The Journal of Organic Chemistry, 2024, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.3c02867

Rapid and Direct Photocatalytic C(sp3)‒H Acylation and Arylation in Flow

Autori: Daniele Mazzarella, Antonio Pulcinella, Loic Bovy, Remy Broersma, Timothy Noel
Pubblicato in: Angewandte Chemie International Edition, 2021, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202108987

Photo‐Induced Ruthenium‐Catalyzed C−H Arylation Polymerization at Ambient Temperature

Autori: Takuya Michiyuki, Isaac Maksso, Lutz Ackermann
Pubblicato in: Angewandte Chemie International Edition, Numero 63, 2024, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202400845

Photocatalytic Late-stage Functionalization of Dehydroalanine-derived Peptides in Batch and Flow

Autori: Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel Gryko, Timothy Noel
Pubblicato in: ChemRxiv, 2024, ISSN 2573-2293
Editore: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2024-6fgqv

2-(o-Tolyl) Pyridine as Ligand Improves the Efficiency in Ketone Directed ortho-Arylation

Autori: Nanditha Kattukudiyil Narayanan, Prof. Dr. Ernst Pittenauer, Prof. Dr. Michael Schnürch
Pubblicato in: European Journal of Organic Chemistry, 2023, ISSN 1434-193X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202300759

Metal-free photocatalytic cross-electrophile coupling enables C1 homologation and alkylation of carboxylic acids with aldehydes

Autori: Stefano Bonciolini, Antonio Pulcinella, Matteo Leone, Debora Schiroli, Adrián Luguera Ruiz, Andrea Sorato, Maryne A. J. Dubois, Ranganath Gopalakrishnan, Geraldine Masson, Nicola Della Ca’, Stefano Protti, Maurizio Fagnoni, Eli Zysman-Colman, Magnus Johansson, Timothy Noël
Pubblicato in: Nature Communications, 2024, ISSN 2041-1723
Editore: Nature Publishing Group
DOI: 10.1038/s41467-024-45804-z

Efficient synthesis of 2‐arylpropionitriles via selective monomethylation of aryl acetonitriles using an easy to handle methylation agent

Autori: Eleni Papaplioura, Johanna Templ, Nina Wildhack, Michael Schnürch
Pubblicato in: European Journal of Organic Chemistry, 2024, ISSN 1434-193X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202400693

Remote C−H Glycosylation by Ruthenium(II) Catalysis: Modular Assembly of meta-C-Aryl Glycosides

Autori: Jun Wu, Dr. Nikolaos Kaplaneris, Julia Pöhlmann, Takuya Michiyuki, Binbin Yuan, Prof. Dr. Lutz Ackermann
Pubblicato in: Angew Chem. Int. Ed., 2022, ISSN 1433-7851
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202208620

Adding value to terpenes: copper-catalyzed oxidation of α-pinene in water under micellar conditions

Autori: Gilvan A. Correia, Chris H. J. Franco, Marina V. Kirillova, Fabrice Gallou, Alexander M. Kirillov
Pubblicato in: Green Chemistry, 2025, ISSN 1463-9262
Editore: Royal Society of Chemistry
DOI: 10.1039/d4gc06525e

Pd-Catalyzed C(sp²)–H/C(sp²)–H Coupling of Limonene

Autori: Marco Di Matteo, Anna Gagliardi, Alexandre Pradal, Luis F. Veiros, Fabrice Gallou, Giovanni Poli
Pubblicato in: The Journal of Organic Chemistry, Numero 89, 2024, Pagina/e 10451-10461, ISSN 0022-3263
Editore: American Chemical Society
DOI: 10.1021/acs.joc.4c00501

Thesis and dissertations (3)

Selective C-H Activation of Terpenes

Autori: Marco Di Matteo
Pubblicato in: 2024
Editore: HAL

Application of non-volatile reagents for the introduction of short hydrocarbon chains

Autori: Eleni Papaplioura
Pubblicato in: 2024
Editore: reposiTUm
DOI: 10.34726/hss.2024.95824

Photocatalytic strategies for the valorization of feedstock chemicals in batch and flow

Autori: Antonio Pulcinella
Pubblicato in: 2025
Editore: UvA-DARE

Book chapters (1)

The chemistry of 1,4-dihydropyrrolo[3,2-b]pyrroles

Autori: Gana Sanil, Beata Koszarna, Yevgen M.Poronik, Olena Vakuliuk, Bartosz Szymański, Damian Kusy, Daniel T. Gryko
Pubblicato in: Advances in Heterocyclic Chemistry, 2022, Pagina/e 335-409
Editore: Elsevier
DOI: 10.1016/bs.aihch.2022.04.002

Other (1)

Late-Stage Heteroarene Alkylation via Minisci Reaction with Gaseous Alkanes Enabled by Hydrogen Atom Transfer in Flow

Autori: Prakash Chandra Tiwari, Antonio Pulcinella, Emil Hodzic, Timothy Noel
Pubblicato in: 2025
Editore: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2025-wr8br