Training network for research into bone Fragility In Diabetes in Europe – towards a personaLised medIcine apprOach

Deliverables

Other (1)

ESR application pack

To be available to all applicants as a pdf file

Websites, patent fillings, videos etc. (1)

Communication plan and resource pack

Including protocols key messages logo templates and styles

Publications

Peer reviewed articles (10)

Type 2 Diabetes Mellitus and Vertebral Fracture Risk

Author(s): Fjorda Koromani, Samuel Ghatan, Mandy van Hoek, M. Carola Zillikens, Edwin H. G. Oei, Fernando Rivadeneira & Ling Oei
Published in: Current Osteoporosis Reports, 19, 2021, Page(s) 50-57, ISSN 1544-1873
Publisher: Current Science Inc.
DOI: 10.1007/s11914-020-00646-8

Bone fragility in diabetes: novel concepts and clinical implications

Author(s): Lorenz C Hofbauer, Björn Busse, Richard Eastell, Serge Ferrari, Morten Frost, Ralph Müller, Andrea M Burden, Fernando Rivadeneira, Nicola NapoliMartina Rauner
Published in: The Lancet Diabetes and Endocrinology, 10, 3, 2022, Page(s) 207-220, ISSN 2213-8587
Publisher: Elsevier BV
DOI: 10.1016/s2213-8587(21)00347-8

Meta-analysis of Diabetes Mellitus-Associated Differences in Bone Structure Assessed by High-Resolution Peripheral Quantitative Computed Tomography

Author(s): Matthias Walle Danielle E Whittier, Morten Frost, Ralph Müller, Caitlyn J Collins
Published in: Current Osteoporosis Reports, 15442241, 2022, ISSN 1544-2241
Publisher: Springer
DOI: 10.1007/s11914-022-00755-6

Effect of Anti-Osteoporotic Treatments on Circulating and Bone MicroRNA Patterns in Osteopenic ZDF Rats

Author(s): Carro Vázquez, D.; Emini, L.; Rauner, M.; Hofbauer, C.; Grillari, J.; Diendorfer, A.B.; Eastell, R.; Hofbauer, L.C.; Hackl, M.
Published in: International Journal of Molecular Sciences, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126534

Bone Mechanoregulation Allows Subject-Specific Load Estimation Based on Time-Lapsed Micro-CT and HR-pQCT in Vivo

Author(s): Matthias Walle, Francisco C. Marques, Nicholas Ohs, Michael Blauth, Ralph Müller, Caitlyn J. Collins
Published in: Frontiers in Bioengineering and Biotechnology, 9, 2021, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2021.677985

The Gut Microbiome: a New Frontier in Musculoskeletal Research

Author(s): R. Li; C. G. Boer; L. Oei; Carolina Medina-Gomez
Published in: Current Osteoporosis Reports, 19, 2021, Page(s) 347–357, ISSN 1544-2241
Publisher: Springer Nature
DOI: 10.1007/s11914-021-00675-x

Motion grading of high-resolution quantitative computed tomography supported by deep convolutional neural networks

Author(s): Matthias Walle, Dominic Eggemann, Penny R. Atkins, Jack Kendall, Kerstin Stock, Ralph Müller, Caitlyn J. Collins
Published in: Bone, 87563282, 2022, ISSN 8756-3282
Publisher: Elsevier BV
DOI: 10.1016/j.bone.2022.116607

The Treatment Gap in Osteoporosis

Author(s): Nazia Ayub ,Malak Faraj ,Sam Ghatan ,Joannes A. A. Reijers, Nicola Napoli and Ling Oei
Published in: Journal of Clinical Medicine, 10, 2021, Page(s) 3002, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm10133002

The Polygenic and Monogenic Basis of Paediatric Fractures

Author(s): S. Ghatan, A. Costantini, R. Li, C. De Bruin, N. M. Appelman-Dijkstra, E. M. Winter, L. Oei & Carolina Medina-Gomez
Published in: Current Osteoporosis Reports, 19, 2021, Page(s) 481–493, ISSN 1544-2241
Publisher: Springer Nature
DOI: 10.1007/s11914-021-00680-0

Circulating miRNAs in bone health and disease

Author(s): Johannes Grillari, Riikka E. Mäkitie, Roland Kocijan, Judith Haschka, David Carro Vázquez, Elisabeth Semmelrock, Matthias Hackl
Published in: Bone, 145, 2021, Page(s) 115787, ISSN 1873-2763
Publisher: Elsevier
DOI: 10.1016/j.bone.2020.115787

Conference proceedings (10)

Type 2 diabetes clusters indicate diabetes duration key in fracture risk

Author(s): Samuel Ghatan, Fariba Ahmadizar, Ruolin Li, M. Carola Zillikens, Carolina Medina-Gomez, Fernando Rivadenira, Maryam Kavousi, Ling Oei.
Published in: Endocrine Abstracts, 73, 2021, Page(s) ea0073pep2.2, ISSN 1479-6848
Publisher: Bioscientifica
DOI: 10.1530/endoabs.73.pep2.2

Development of diabetes-sensitive fracture resistance analysis using finite element method to predict diabetic bone fragility and bone quality

Author(s): Cemre Yavuz, Eva Maria Wölfel, Katharina Jähn-Rickert, Herbert Mushumba, Birgit Wulff, Klaus Püschel, Bjoern Busse, Mahan Qwamizadeh
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100883, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100883

A 20-year comparison of sex-specific fracture incidence between Type 1 and Type 2 diabetics and non-diabetics in Denmark

Author(s): Mohamad Nasser, Annika Kvist, Morten Frost, Peter Vestergaard, Andrea M. Burden
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100822, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100771

MicroRNAs in diabetic bone disease: A systematic review

Author(s): Ankita Duseja, Lisa Dowling, Tatiane Vilaca, Patryk Zarecki, Richard Eastell, Matthias Hackl
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100876, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100876

Tissue-level mechanical stimuli drive bone formation and resorption in humans and mice

Author(s): Matthias Walle, Francisco C. Marques, Nicholas Ohs, Michael Blauth, Ralph Müller, Caitlyn J. Collins
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 101032, ISSN 2352-1872
Publisher: Eksevier
DOI: 10.1016/j.bonr.2021.101032

Type 2 diabetes clusters indicate diabetes duration key in fracture risk

Author(s): Samuel Ghatan, Fariba Ahmadizar, Ruolin Li, M. Carola Zillikens, Carolina Medina-Gomez, Fernando Rivadenira, Maryam Kavousi, Ling Oei
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100822, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100822

3D physiological load estimation based on time-lapsed HR-pQCT images.

Author(s): M. Walle, F. C. Marques, N. Ohs, R. Müller, and C. J. Collins
Published in: Journal of Bone and Mineral Research, Volume 35, Issue S1, 2020, Page(s) 143-144, ISSN 1523-4681
Publisher: Wiley
DOI: 10.1002/jbmr.4206

Femur specimens from type 1 diabetes mellitus individuals presented with unaffected cortical bone matrix quality, but altered cellular histomorphometry

Author(s): Sofie Kolibova, Eva Maria Wölfel, Haniyeh Hemmatian, Herbert Mushumba, Birgit Wulff, Klaus Püschel, Björn Busse, Katharina Jähn-Rickert
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100886, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100886

Circulating microRNA analysis in ZDF rats as a model for the identification of biomarkers and disease mechanisms in diabetic osteopathy

Author(s): David Carro Vázquez, Christine Hofbauer, Lejla Emini, Martina Rauner, Johannes Grillari, Richard Eastell, Lorenz Hofbauer, Matthias Hackl
Published in: Bone Reports, Volume 14, Supplement, 2021, Page(s) 100803, ISSN 2352-1872
Publisher: Elsevier
DOI: 10.1016/j.bonr.2021.100803

Type 2 Diabetes Clusters Indicate Diabetes Duration Key in Fracture Risk

Author(s): Samuel Ghatan, Fariba Ahmadizar, Ruolin Li, M. Carola Zillikens, Carolina Medina-Gomez, Fernando Rivadenira, Maryam Kavousi, Ling Oei.
Published in: Journal of the Endocrine Society, Volume 5, Supplement 1, 2021, Page(s) A280–A281, ISSN 2472-1972
Publisher: Oxford University Press
DOI: 10.1210/jendso/bvab048.570

Other (1)

Circulating miRNAs associated with diabetes mellitus and altered bone phenotype: a systematic review

Author(s): Ankita Duseja, Lisa Dowling
Published in: PROSPERO International prospective register of systematic reviews, 2020, Page(s) CRD42020212451
Publisher: Centre for Reviews and Dissemination, University of York