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Multidisciplinary Training in Chronic Kidney Disease: from genetic modifiers to drug discovery

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan

Formulation of a Data Management Plan

Publications

The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells

Author(s): Aurore Claude-Taupin, Pierre Isnard, Alessia Bagattin, Nicolas Kuperwasser, Federica Roccio, Biagina Ruscica, Nicolas Goudin, Meriem Garfa-Traoré, Alice Regnier, Lisa Turinsky, Martine Burtin, Marc Foretz, Marco Pontoglio, Etienne Morel, Benoit Viollet, Fabiola Terzi, Patrice Codogno, Nicolas Dupont
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-43775-1

Genetic determinants of complement activation in the general population

Author(s): Damia Noce, Luisa Foco, Dorothea Orth-Höller, Eva König, Giulia Barbieri, Maik Pietzner, Dariush Ghasemi-Semeskandeh, Stefan Coassin, Christian Fuchsberger, Martin Gögele, Fabiola Del Greco M., Alessandro De Grandi, Monika Summerer, Eleanor Wheeler, Claudia Langenberg, Cornelia Lass-Flörl, Peter Paul Pramstaller, Florian Kronenberg, Reinhard Würzner, Cristian Pattaro
Published in: Cell Reports, Issue 43, 2024, Page(s) 113611, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113611

The membrane transporter SLC25A48 enables transport of choline into human mitochondria

Author(s): Suraj Patil, Oleg Borisov, Nora Scherer, Christophe Wirth, Pascal Schlosser, Matthias Wuttke, Sandra Ehret, Luciana Hannibal, Kai-Uwe Eckardt, Carola Hunte, Björn Neubauer, Anna Köttgen, Michael Köttgen
Published in: Kidney International, 2024, ISSN 0085-2538
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.kint.2024.06.022

Comparison of glomerular filtration rate estimating formulas among Japanese adults without kidney disease

Author(s): Ryosuke Fujii, Cristian Pattaro, Yoshiki Tsuboi, Yuya Ishihara, Roberto Melotti, Hiroya Yamada, Yoshitaka Ando, Hiroaki Ishikawa, Koji Ohashi, Shuji Hashimoto, Nobuyuki Hamajima, Giulia Barbieri, Dariush Ghasemi-Semeskandeh, Koji Suzuki
Published in: Clinical Biochemistry, Issue 111, 2023, Page(s) 54-59, ISSN 0009-9120
Publisher: Elsevier BV
DOI: 10.1016/j.clinbiochem.2022.10.011

Meta-GWAS Reveals Novel Genetic Variants Associated with Urinary Excretion of Uromodulin

Author(s): Christina B. Joseph, Marta Mariniello, Ayumi Yoshifuji, Guglielmo Schiano, Jennifer Lake, Jonathan Marten, Anne Richmond, Jennifer E. Huffman, Archie Campbell, Sarah E. Harris, Stephan Troyanov, Massimiliano Cocca, Antonietta Robino, Sébastien Thériault, Kai-Uwe Eckardt, Matthias Wuttke, Yurong Cheng, Tanguy Corre, Ivana Kolcic, Corrinda Black, Vanessa Bruat, Maria Pina Concas, Cinzia Sala, Stef
Published in: The Journal of the American Society of Nephrology, Issue Vol. 33, Issue 3 March 2022, 2022, Page(s) 511-529, ISSN 1533-3450
Publisher: American Society of Nephrology
DOI: 10.1681/asn.2021040491

Comparison of glomerular filtration rate estimating formulas among Japanese adults without kidney disease

Author(s): Ryosuke Fujii, Cristian Pattaro, Yoshiki Tsuboi, Yuya Ishiharab Roberto Melotti, Hiroya Yamada, Yoshitaka Ando, Hiroaki Ishikawa, Koji Ohashi, Shuji Hashimoto Nobuyuki Hamajima, Giulia Barbieri, Dariush Ghasemi-Semeskandeh, Koji Suzukib
Published in: Clinical Biochimestry, 2022, ISSN 0009-9120
Publisher: Elsevier BV
DOI: 10.1101/2022.12.16.22283452

Structural equation modeling (SEM) of kidney function markers and longitudinal CVD risk assessment

Author(s): Ryosuke Fujii, Roberto Melotti, Martin Gögele, Laura Barin, Dariush Ghasemi-Semeskandeh, Giulia Barbieri, Peter P. Pramstaller, Cristian Pattaro
Published in: PLOS ONE, Issue 18, 2023, Page(s) e0280600, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0280600

Allelic effects on uromodulin aggregates drive autosomal dominant tubulointerstitial kidney disease

Author(s): Guglielmo Schiano Jennifer Lake Marta Mariniello Céline Schaeffer Marianne Harvent Luca Rampoldi Eric Olinger Olivier Devuyst
Published in: EMBO Molecular Medicine, 2023, ISSN 1757-4684
Publisher: EMBOPress
DOI: 10.15252/emmm.202318242

Enhanced sequencing with UMIs

Author(s): Claudio Novella-Raussell Magda Grudniewska-Lauwton
Published in: 2021
Publisher: Genomescan

Systematic mediation and interaction analyses in an individual population study help characterize kidney function genetic loci.

Author(s): Ghasemi-Semeskandeh D, Emmert D, König E, et al.
Published in: 2023
Publisher: medRxiv
DOI: 10.1101/2023.04.15.23288540

Phenotypic spectrum of FAM47E-SHROOM3 haplotype composition in a general population sample

Author(s): Ghasemi-Semeskandeh D, König E, Foco L, et al.
Published in: 2024
Publisher: medrxiv
DOI: 10.1101/2024.03.22.24304731

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