Project description DEENESFRITPL Reducing infection in orthopaedics In orthopaedic implants, such as joint prostheses, postoperative infections by antibiotic-resistant bacteria are on the rise, representing a heavy burden for patients and healthcare systems. This is why the prevention of biofilm formation on the surface of the implants is important. The EU-funded AIMed project will develop a series of biomaterials with anti-bacterial properties. Laser processing will be used to make the biomaterials more resistant to the formation of biofilms. The project, which consists of a network of 12 beneficiaries and six partner institutions, will test the properties of the new materials to demonstrate that they are suitable for use in future implant interventions. Show the project objective Hide the project objective Objective The AIMed network, consisting of 12 beneficiaries and 6 partner organisations, will develop a range of materials with anti-bacterial properties that are suitable for use on the surfaces of orthopaedic implants. This is in response to the increasing problem of post-operative infection by antibiotic-resistant bacteria. By combining several approaches to disrupt surface biofilm formation, the materials developed by the AIMed network will eventually result in fewer surgical infections, faster recovery of patients, and greatly reduced post-operative healthcare costs. The network will develop novel peptide sequences and ways of binding them to the surfaces of olymers, ceramics and metals. A complementary approach will be the developent of metal ion substituted calcium phosphate coatings which can be applied to implants by additive manufacturing techniques. The efficacy of these anti-bacterial surfaces will be further enhanced by laser processing of the material to make it unattractive to biofilms (by altering the roughness and wetting characteristics). The network will carry out a thorough investigation of the properties of the new materials to ensure that they are feasible for use in future implants. This work will include the evaluation of antibacterial action and biocompatibility using appropriate models. Training of the 15 ESR's appointed to the network will be multi-disciplinary and intersectoral, with an emphasis on the need for technology transfer from academic institutions to commercial users. Fields of science engineering and technologymaterials engineeringcoating and filmsmedical and health sciencesclinical medicineorthopaedicsengineering and technologymechanical engineeringmanufacturing engineeringadditive manufacturingmedical and health sciencesmedical biotechnologyimplantsengineering and technologymaterials engineeringceramics Keywords Antimicrobial peptides surface modification ceramics polymers metal alloys polypeptides medical device Programme(s) H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers Topic(s) MSCA-ITN-2019 - Innovative Training Networks Call for proposal H2020-MSCA-ITN-2019 See other projects for this call Funding Scheme MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN) Coordinator THE UNIVERSITY OF BIRMINGHAM Net EU contribution € 909 517,68 Address Edgbaston B15 2TT Birmingham United Kingdom See on map Region West Midlands (England) West Midlands Birmingham Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (11) Sort alphabetically Sort by Net EU contribution Expand all Collapse all INSTITUT NATIONAL POLYTECHNIQUE DE TOULOUSE France Net EU contribution € 274 802,04 Address Allee emile monso 6 31029 Toulouse cedex 4 See on map Region Occitanie Midi-Pyrénées Haute-Garonne Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITE PAUL SABATIER TOULOUSE III France Net EU contribution € 274 802,04 Address Route de narbonne 118 31062 Toulouse cedex 9 See on map Region Occitanie Midi-Pyrénées Haute-Garonne Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITE POLYTECHNIQUE HAUTS-DE-FRANCE France Net EU contribution € 274 802,04 Address Le mont houy 59313 Valenciennes cedex 9 See on map Region Hauts-de-France Nord-Pas de Calais Nord Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITA DEGLI STUDI DI TRIESTE Italy Net EU contribution € 261 499,68 Address Piazzale europa 1 34127 Trieste See on map Region Nord-Est Friuli-Venezia Giulia Trieste Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITY OF LIMERICK Participation ended Ireland Net EU contribution € 0,00 Address National technological park, plassey - Limerick See on map Region Ireland Northern and Western Border Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSIDADE DO PORTO Portugal Net EU contribution € 237 720,24 Address Praca gomes teixeira 4099-002 Porto See on map Region Continente Norte Área Metropolitana do Porto Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 RUDER BOSKOVIC INSTITUTE Croatia Net EU contribution € 237 367,08 Address Bijenicka cesta 54 10000 Zagreb See on map Region Hrvatska Grad Zagreb Grad Zagreb Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG Germany Net EU contribution € 442 379,70 Address Schlossplatz 4 91054 Erlangen See on map Region Bayern Mittelfranken Erlangen, Kreisfreie Stadt Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT PRO ELEKTRONIKA NA BAN - INSTITUTE OF ELECTRONICS BULGARIAN ACADEMY OF SCIENCES Bulgaria Net EU contribution € 617 127,00 Address Tsarigradsko shosse boulevard 72 1784 Sofia See on map Region Югозападна и Южна централна България Югозападен София (столица) Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 REGEMAT 3D LTD Participation ended Spain Net EU contribution € 62 726,22 Address Avenida de la innovacion 1 18100 Armilla See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Sur Andalucía Granada Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 PHOTON ENERGY GmbH Germany Net EU contribution € 252 788,40 Address Braunleinsberg 10 91242 Ottensoos See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Bayern Mittelfranken Nürnberger Land Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00