Project description
Reducing infection in orthopaedics
In orthopaedic implants, such as joint prostheses, postoperative infections by antibiotic-resistant bacteria are on the rise, representing a heavy burden for patients and healthcare systems. This is why the prevention of biofilm formation on the surface of the implants is important. The EU-funded AIMed project will develop a series of biomaterials with anti-bacterial properties. Laser processing will be used to make the biomaterials more resistant to the formation of biofilms. The project, which consists of a network of 12 beneficiaries and six partner institutions, will test the properties of the new materials to demonstrate that they are suitable for use in future implant interventions.
Objective
The AIMed network, consisting of 12 beneficiaries and 6 partner organisations, will develop a range of materials with anti-bacterial properties that are suitable for use on the surfaces of orthopaedic implants. This is in response to the increasing problem of post-operative infection by antibiotic-resistant bacteria. By combining several approaches to disrupt surface biofilm formation, the materials developed by the AIMed network will eventually result in fewer surgical infections, faster recovery of patients, and greatly reduced post-operative healthcare costs. The network will develop novel peptide sequences and ways of binding them to the surfaces of olymers, ceramics and metals. A complementary approach will be the developent of metal ion substituted calcium phosphate coatings which can be applied to implants by additive manufacturing techniques. The efficacy of these anti-bacterial surfaces will be further enhanced by laser processing of the material to make it unattractive to biofilms (by altering the roughness and wetting characteristics). The network will carry out a thorough investigation of the properties of the new materials to ensure that they are feasible for use in future implants. This work will include the evaluation of antibacterial action and biocompatibility using appropriate models. Training of the 15 ESR's appointed to the network will be multi-disciplinary and intersectoral, with an emphasis on the need for technology transfer from academic institutions to commercial users.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules
- natural sciences chemical sciences inorganic chemistry alkaline earth metals
- engineering and technology materials engineering coating and films
- medical and health sciences medical biotechnology implants
- engineering and technology materials engineering ceramics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-ITN - Marie Skłodowska-Curie Innovative Training Networks (ITN)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-ITN-2019
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
B15 2TT Birmingham
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.