Descrizione del progetto
Una migliore diagnostica potrebbe far luce sulla carenza di vitamina D
Sempre più evidenze sostengono oggi gli importanti ruoli della vitamina D nei tessuti extrascheletrici, oltre a sostenere come l’insufficienza di vitamina D possa incidere su patologie che vanno dal cancro alle malattie cardiovascolari. Le quantità necessarie per la salute sono inoltre probabilmente più alte di quanto si pensasse. Al tempo stesso, la carenza o l’insufficienza di vitamina D è in aumento. Sebbene le stime varino, l’evidenza suggerisce che oltre un miliardo di persone a livello globale (oltre il 10 % della popolazione) mostra una carenza o un’insufficienza di vitamina D. Il progetto OSAvit-D sta sviluppando un dispositivo economico di diagnostica decentrata, per lo screening diffuso durante le visite ambulatoriali e sul campo. In tal modo si migliorerà e si consentirà il rilevamento precoce e il trattamento della carenza potenzialmente dannosa e sempre più diffusa di vitamina D.
Obiettivo
OSASEN is a young technological SME focused on the development of novel biosensors for healthcare (Point of Care-PoC devices), addressing priority needs in healthcare diagnostics and/or therapies monitoring for the benefit of patients, providing affordable systems with unique features that meet specific well identified requirements in healthcare. OSASEN has recently identified a healthcare need in relation with prevention, treatment and monitoring of Vitamin D (VitD) deficiency. VitD (1,25-DihydroxyvitaminD) is considered a multipurpose steroid hormone that in human plays an essential role in multiple aspects, being its primary role to participate in the regulation of metabolism of calcium and phosphorous. VitD deficiency is evident throughout the European population at a prevalence of 13% (FP7-613977-ODIN project), a rate that is a matter of concern. People over 50 have an increased risk of vitamin D deficiency with consequent bone loss risk leading to osteoporosis and fractures. Emerging evidence has shown that VitD administration improves muscle performance and reduces falls in VitD deficient older adults. Other populations of higher risk for VitD deficiency are children, pregnant and lactating women and patients with digestive disorders, among others. VitD deficiency is also associated with increased risk of cancer, cardiovascular disease, infections, and autoimmune diseases. For example, several studies have shown that VitD levels are lower in Multiple Sclerosis patients, and monitoring and VitD supplementation to them is highly recommended. In this context, OSASEN has identified the opportunity to develop a novel PoC device for the quantification of VitD in blood or urine based on lateral flow (LF) immunoassay, combined with electrochemical detection on screen printed electrodes (SPEs). For doing so, it is necessary to incorporate an expert in LF immunoassays and antibody selection, conjugation, handling & stabilization to OSASEN’s team.
Campo scientifico
- engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensors
- medical and health sciencesbasic medicineneurologymultiple sclerosis
- medical and health sciencesbasic medicineimmunologyautoimmune diseases
- medical and health sciencesclinical medicinecardiologycardiovascular diseases
- medical and health sciencesclinical medicineoncology
Programma(i)
Invito a presentare proposte
Vedi altri progetti per questo bandoBando secondario
H2020-INNOSUP-2019-02
Meccanismo di finanziamento
CSA - Coordination and support actionCoordinatore
48160 DERIO
Spagna
L’organizzazione si è definita una PMI (piccola e media impresa) al momento della firma dell’accordo di sovvenzione.