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Safety BY Design Of nanoMaterials - From Lab Manufacture to Governance and Communication: Progressing Up the TRL Ladder

Description du projet

«Sécurité dès la conception» – Vers des applications nanotechnologiques plus sûres

L’ingénierie des nanomatériaux à hautes performances ouvre de grandes perspectives dans de nombreux domaines, notamment la médecine, l’électronique et l’énergie. Pour être en mesure de fabriquer des nanomatériaux en quantités modulables et utilisables en toute sécurité, de nouvelles méthodologies de synthèse des nanomatériaux doivent être explorées, afin d’étudier leur impact sur les humains et l’environnement dès le début du processus. L’un des principaux objectifs du projet SABYDOMA, financé par l’UE, consiste à créer des plateformes en ligne à haut débit où les nanomatériaux sont fabriqués et passés au crible sur le lieu de production. Un autre objectif est d’étendre le champ d’application des nanomatériaux «sûrs dès la conception» à des situations réelles. Le projet examinera quatre études de cas industrielles mises en place par quatre partenaires de l’industrie afin de passer du niveau de maturité technologique 4 au niveau 6.

Objectif

The SABYDOMA programme addresses developments in the safety by design (SbD) paradigm by examining four industrial case studies in detail where the TRLs will advance from 4 to 6. Each TRL activity will progress from being lab based at TRL4 to being industry based at TRL6. The TRL4 activity will involve only innovation with regular industrial communication whereas the TRL6 activity will involve industrially located activities with innovation communication. One of the novel themes of this study is to use system control and optimisation theory including the Model Predictive Control (MPC) philosophy to bind the whole subject of SbD from laboratory innovation to the industrial production line and from decision making processes to project governance. An equally important innovative step is the building of high throughput online platforms where nanomaterial (NM) is manufactured and screened at the point of production. The screening signal controls the NM redesign and production in a feedback loop. Screens will involve (a) physiochemical sensing elements (b) in-vitro targets of increasing complexity from the 2D biomembrane to cell-line and more complex cell-line elements; and, (c) multiple in-vitro targets with multiple end-points; developed in current H2020 projects. Two of the industrial studies include composite coating manufacture where the coating’s stability and toxicity will be tested using a flow through microfluidic flow cell system coupled to online screens. This is part of the release and ageing investigations on the NM and NM coatings and the results of these will feed back to the production line design. At every step on the TRL ladder the in-silico modelling will be applied to optimise and redefine the relevant activities. By the same token regulatory and governance principles of SbD will be used to refine the technological development. The final deliverable will be four distinct technologies applying SbD to the four industrial processes respectively.

Appel à propositions

H2020-NMBP-TO-IND-2018-2020

Voir d’autres projets de cet appel

Sous appel

H2020-NMBP-TO-IND-2019

Coordinateur

UNIVERSITY OF LEEDS
Contribution nette de l'UE
€ 1 163 977,50
Adresse
WOODHOUSE LANE
LS2 9JT Leeds
Royaume-Uni

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Région
Yorkshire and the Humber West Yorkshire Leeds
Type d’activité
Higher or Secondary Education Establishments
Liens
Coût total
€ 1 163 977,50

Participants (20)