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Safety BY Design Of nanoMaterials - From Lab Manufacture to Governance and Communication: Progressing Up the TRL Ladder

Descripción del proyecto

«Seguridad mediante el diseño» para aplicaciones más seguras de la nanotecnología

Los nanomateriales artificiales de altas prestaciones son muy prometedores para distintos campos, como la medicina, la electrónica y la energía. Para lograr cantidades escalables de nanomateriales seguros para el uso, es necesario examinar nuevos métodos de síntesis y estudiar el efecto que tienen los nanomateriales sobre los humanos y el medio ambiente desde el principio del proceso. Uno de los objetivos principales del proyecto SABYDOMA, financiado con fondos europeos, es desarrollar plataformas en línea de alta capacidad donde sea posible fabricar nanomateriales y evaluarlos en el punto de fabricación. Otro objetivo es ampliar el efecto de los nanomateriales seguros mediante el diseño a las situaciones del mundo real. El proyecto analizará cuatro estudios de casos industriales elaborados por cuatro socios industriales con el fin de avanzar en el nivel de preparación tecnológica del 4 al 6.

Objetivo

The SABYDOMA programme addresses developments in the safety by design (SbD) paradigm by examining four industrial case studies in detail where the TRLs will advance from 4 to 6. Each TRL activity will progress from being lab based at TRL4 to being industry based at TRL6. The TRL4 activity will involve only innovation with regular industrial communication whereas the TRL6 activity will involve industrially located activities with innovation communication. One of the novel themes of this study is to use system control and optimisation theory including the Model Predictive Control (MPC) philosophy to bind the whole subject of SbD from laboratory innovation to the industrial production line and from decision making processes to project governance. An equally important innovative step is the building of high throughput online platforms where nanomaterial (NM) is manufactured and screened at the point of production. The screening signal controls the NM redesign and production in a feedback loop. Screens will involve (a) physiochemical sensing elements (b) in-vitro targets of increasing complexity from the 2D biomembrane to cell-line and more complex cell-line elements; and, (c) multiple in-vitro targets with multiple end-points; developed in current H2020 projects. Two of the industrial studies include composite coating manufacture where the coating’s stability and toxicity will be tested using a flow through microfluidic flow cell system coupled to online screens. This is part of the release and ageing investigations on the NM and NM coatings and the results of these will feed back to the production line design. At every step on the TRL ladder the in-silico modelling will be applied to optimise and redefine the relevant activities. By the same token regulatory and governance principles of SbD will be used to refine the technological development. The final deliverable will be four distinct technologies applying SbD to the four industrial processes respectively.

Convocatoria de propuestas

H2020-NMBP-TO-IND-2018-2020

Consulte otros proyectos de esta convocatoria

Convocatoria de subcontratación

H2020-NMBP-TO-IND-2019

Régimen de financiación

RIA - Research and Innovation action

Coordinador

UNIVERSITY OF LEEDS
Aportación neta de la UEn
€ 1 163 977,50
Dirección
WOODHOUSE LANE
LS2 9JT Leeds
Reino Unido

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Región
Yorkshire and the Humber West Yorkshire Leeds
Tipo de actividad
Higher or Secondary Education Establishments
Enlaces
Coste total
€ 1 163 977,50

Participantes (20)