Deciphering the principles governing robust targeting of proteins to organelles

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

A Similarity-Based Method for Predicting Enzymatic Functions in Yeast Uncovers a New AMP Hydrolase

Author(s): Nir Cohen Amit Kahana MayaSchuldiner
Published in: Journal of Molecular Biology, 2022, Page(s) 167478, ISSN 0022-2836
Publisher: Academic Press
DOI: 10.1016/j.jmb.2022.167478

Pls1 Is a Peroxisomal Matrix Protein with a Role in Regulating Lysine Biosynthesis

Author(s): Yotam David; Inês Gomes Castro; Eden Yifrach; Chen Bibi; Enas Katawi; Dekel Yahav Har-Shai; Sagie Brodsky; Naama Barkai; Tommer Ravid; Miriam Eisenstein; Shmuel Pietrokovski; Maya Schuldiner; Einat Zalckvar
Published in: Cells; Volume 11; Issue 9; Pages: 1426, Issue 1, 2022, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells11091426

ER-SURF: Riding the Endoplasmic Reticulum Surface to Mitochondria

Author(s): Christian Koch; Maya Schuldiner; Johannes Herrmann
Published in: International Journal of Molecular Sciences, 2021, Page(s) 9655, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179655

Beyond rare disorders: A new era for peroxisomal pathophysiology

Author(s): Einat Zalckvar; Maya Schuldiner
Published in: Molecular Cell, Issue 1, 2022, ISSN 1097-2765
Publisher: Cell Press
DOI: 10.1016/j.molcel.2022.05.028

Phosphorylation of the receptor protein Pex5p modulates import of proteins into peroxisomes

Author(s): Sven Fischer, Jérôme Bürgi, Shiran Gabay-Maskit, Renate Maier, Thomas Mastalski, Eden Yifrach, Agnieszka Obarska-Kosinska, Markus Rudowitz, Ralf Erdmann, Harald W Platta, Matthias Wilmanns, Maya Schuldiner, Einat Zalckvar, Silke Oeljeklaus, Friedel Drepper, Bettina Warscheid
Published in: Biological Chemistry, 2022, ISSN 1431-6730
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/hsz-2022-0168

Systematic Approaches to Study Eclipsed Targeting of Proteins Uncover a New Family of Mitochondrial Proteins

Author(s): Mark M, Klein O, Zhang Y, Das K, Elbaz A, Hazan RN, Lichtenstein M, Lehming N, Schuldiner M, Pines O
Published in: Cells, Issue 12(11), 2023, Page(s) 1550, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells12111550

Peroxisome function relies on organelle-associated mRNA translation

Author(s): Noa Dahan, Yury S Bykov, Elizabeth A Boydston, Amir Fadel, Zohar Gazi, Hodaya Hochberg-Laufer, James Martenson, Vlad Denic, Yaron Shav-Tal , Jonathan S Weissman, Naama Aviram, Einat Zalckvar, Maya Schuldiner
Published in: Science Advances, 2022, Page(s) eabk2141, ISSN 2375-2548
Publisher: AAAS
DOI: 10.1126/sciadv.abk2141

Sec61 channel subunit Sbh1/Sec61β promotes ER translocation of proteins with suboptimal targeting sequences and is fine-tuned by phosphorylation

Author(s): Guido Barbieri, Julien Simon, Cristina R Lupusella, Fabio Pereira, Francesco Elia, Hadar Meyer, Maya Schuldiner, Steven D Hanes, Duy Nguyen, Volkhard Helms, Karin Römisch
Published in: Journal of Biological Chemistry, 2023, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.102895

A toolbox for systematic discovery of stable and transient protein interactors in baker's yeast

Author(s): Nir Cohen; Zohar Gazi; Emma Fenech; Meital Kupervaser; Maya Schuldiner
Published in: Molecular Systems Biology, Issue 1, 2023, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.202211084

Novel targeting assay uncovers targeting information within peroxisomal ABC transporter Pxa1

Author(s): Renate L.M. Jansen, Marco van den Noort, Arjen M. Krikken, Chen Bibi, Astrid Böhm, Maya Schuldiner, Einat Zalckvar, Ida J. van der Klei
Published in: BBA- Molecular Cell Research, 2023, ISSN 0167-4889
Publisher: Elsevier BV
DOI: 10.1016/j.bbamcr.2023.119471

Determining the targeting specificity of the selective peroxisomal targeting factor Pex9

Author(s): Eden Yifrach, Markus Rudowitz, Luis Daniel Cruz-Zaragoza, Asa Tirosh, Zohar Gazi, Yoav Peleg, Markus Kunze, Miriam Eisenstein, Wolfgang Schliebs, Maya Schuldiner, Ralf Erdmann, Einat Zalckvar
Published in: Biological Chemistry, 2022, ISSN 1431-6730
Publisher: Walter de Gruyter GmbH & Co. KG
DOI: 10.1515/hsz-2022-0116

Widespread use of unconventional targeting signals in mitochondrial ribosome proteins.

Author(s): Yury S. Bykov; Tamara Flohr; Felix Boos; Naama Zung; Johannes M. Herrmann; Maya Schuldiner
Published in: The EMBO Journal, Issue 1, 2022, Page(s) e109519, ISSN 1460-2075
Publisher: EMBO Press
DOI: 10.15252/embj.2021109519

A systematic proximity ligation approach to studying protein-substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Author(s): Nir Cohen, Naama Aviram, Maya Schuldiner
Published in: EMBO Journal, 2023, ISSN 1460-2075
Publisher: EMBO Press
DOI: 10.15252/embj.2022113385

The Fast and the Furious: Golgi Contact Sites

Author(s): Yotam David, Ines Castro, Maya Schuldiner
Published in: Contact, 2021, Page(s) 1-15, ISSN 2515-2564
Publisher: SAGE publishing
DOI: 10.1177/25152564211034424

Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions

Author(s): Eden Yifrach, Duncan Holbrook-Smith, Jérôme Bürgi, Alaa Othman, Miriam Eisenstein, Carlo Wt van Roermund, Wouter Visser, Asa Tirosh, Markus Rudowitz, Chen Bibi, Shahar Galor, Uri Weill, Amir Fadel, Yoav Peleg, Ralf Erdmann, Hans R Waterham, Ronald J A Wanders, Matthias Wilmanns, Nicola Zamboni, Maya Schuldiner, Einat Zalckvar
Published in: Molecular Systems Biology, 2022, ISSN 1744-4292
Publisher: Nature Publishing Group
DOI: 10.15252/msb.202211186

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