Targeting the Plant Cysteine Oxidases to Regulate Plant Stress Tolerance

Project Information

PCOMOD

Grant agreement ID: 864888

DOI

10.3030/864888

EC signature date 5 February 2020

Start date 1 April 2020

End date 31 December 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 995 253,00

EU contribution

€ 1 995 253,00

Coordinated by

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Structures of Arabidopsis thaliana oxygen-sensing plant cysteine oxidases 4 and 5 enable targeted manipulation of their activity

Author(s): Mark D. White, Laura Dalle Carbonare, Mikel Lavilla Puerta, Sergio Iacopino, Martin Edwards, Kate Dunne, Elisabete Pires, Colin Levy, Michael A. McDonough, Francesco Licausi, Emily Flashman
Published in: Proceedings of the National Academy of Sciences, Issue 117/37, 2020, Page(s) 23140-23147, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2000206117

Emerging roles for thiol dioxygenases as oxygen sensors

Author(s): Dona M. Gunawardana, Karen C. Heathcote, Emily Flashman
Published in: The FEBS Journal, 2021, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.16147

Targeting Plant Cysteine Oxidase Activity for Improved Submergence Tolerance

Author(s): Leah J Taylor-Kearney; Emily Flashman
Published in: The Plant Journal, Issue 1365313X, 2021, ISSN 1365-313X
Publisher: Wiley
DOI: 10.1111/tpj.15605

Plant Cysteine Oxidase Oxygen-Sensing Function Is Conserved in Early Land Plants and Algae

Author(s): Leah J. Taylor-Kearney; Samuel Madden; Jack Wilson; William K. Myers; Dona M. Gunawardana; Elisabete Pires; Philip Holdship; Anthony Tumber; Rosalind E. M. Rickaby; Emily Flashman
Published in: ACS Bio & Med Chem Au, Issue 26942437, 2022, ISSN 2694-2437
Publisher: American Chemical Society
DOI: 10.1021/acsbiomedchemau.2c00032

Oxygen-sensing mechanisms across eukaryotic kingdoms and their roles in complex multicellularity

Author(s): Emma U. Hammarlund, Emily Flashman, Sofie Mohlin, Francesco Licausi
Published in: Science, Issue 370/6515, 2020, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.aba3512

Identification of novel plant cysteine oxidase inhibitors from a yeast chemical genetic screen

Author(s): Mikel Lavilla-Puerta, Rebecca Latter, Francesca Bellè, Tiziana Cervelli, Alvaro Galli, Pierdomenico Perata, Andrea Chini, Emily Flashman, Beatrice Giuntoli
Published in: Journal of Biological Chemistry, Issue 299, 2024, Page(s) 105366, ISSN 0021-9258
Publisher: American Society for Biochemistry and Molecular Biology Inc.
DOI: 10.1016/j.jbc.2023.105366

Contrasted NCED gene expression across conifers with rising and peaking abscisic acid responses to drought

Author(s): Gabriele Rizzuto, Dapeng Wang, Jinhui Chen, Tin Hang Hung, Anne Charlott Fitzky, Emily Flashman, John J. MacKay
Published in: Plant Stress, Issue 14, 2025, Page(s) 100574, ISSN 2667-064X
Publisher: Elsevier
DOI: 10.1016/j.stress.2024.100574

Measuring ROS and redox markers in plant cells

Author(s): Salma Akter, Mohammad Shahneawz Khan, Edward N. Smith, Emily Flashman
Published in: RSC Chemical Biology, Issue 2/5, 2021, Page(s) 1384-1401, ISSN 2633-0679
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1cb00071c

N-terminal cysteine acetylation and oxidation patterns may define protein stability

Author(s): Karen C. Heathcote, Thomas P. Keeley, Matti Myllykoski, Malin Lundekvam, Nina McTiernan, Salma Akter, Norma Masson, Peter J. Ratcliffe, Thomas Arnesen, Emily Flashman
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-49489-2

Measuring plant cysteine oxidase interactions with substrates using intrinsic tryptophan fluorescence

Author(s): Dona M. Gunawardana, Daisy A. Southern, Emily Flashman
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-83508-y

Destined for destruction: The role of methionine aminopeptidases and plant cysteine oxidases in N-degron formation

Author(s): Andrea Fuentes-Terrón, Rebecca Latter, Samuel Madden, Isabel Manrique-Gil, Jessenia Estrada, Noelia Arteaga, Inmaculada Sánchez-Vicente, Oscar Lorenzo, Emily Flashman
Published in: Plant Physiology, Issue 197, 2025, ISSN 0032-0889
Publisher: American Society of Plant Biologists
DOI: 10.1093/plphys/kiae667

Book chapters (1)

Kinetic Measurements to Investigate the Oxygen-Sensing Properties of Plant Cysteine Oxidases

Author(s): Anna Dirr, Dona M. Gunawardana, Emily Flashman
Published in: Methods in Molecular Biology, Oxygen Sensing, 2023, Page(s) 207-230
Publisher: Springer US
DOI: 10.1007/978-1-0716-3080-8_13